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Total 517 results found since Jan 2013.

Treatment of eosinophilic esophagitis with diets: an update.
Authors: Lucendo AJ, Molina-Infante J Abstract Eosinophilic esophagitis (EoE) is a chronic inflammatory esophageal disease triggered and maintained predominantly by food antigens. It represents a unique form of non-IgE mediated food allergy, largely dependent upon delayed, cell-mediated hypersensitivity. First-line therapies for EoE consist on drugs with anti-inflammatory effect (mainly including topic steroids and proton pump inhibitors) and dietary therapy. An elimination diet that avoids the consumption of food triggers currently remains the only therapy targeting the cause of EoE. Currently, available food alle...
Source: Minerva Gastroenterologica e Dietologica - November 27, 2019 Category: Gastroenterology Tags: Minerva Gastroenterol Dietol Source Type: research

Usefulness of Nasal Endoscopy for Diagnosing Patients With Chronic Rhinosinusitis: A Meta-Analysis.
PMID: 31775519 [PubMed - as supplied by publisher]
Source: American Journal of Rhinology and Allergy - November 26, 2019 Category: ENT & OMF Authors: Kim DH, Seo Y, Kim KM, Lee S, Hwang SH Tags: Am J Rhinol Allergy Source Type: research

Association of asthma control with allergic rhinitis severity in adult patients
Conclusions: Allergic rhinitis is common comorbidity of asthma that interrelated to asthma control. Identifiable allergens could be detected AR in asthma by SPT. Therefore, reduction of allergens exposure could become preventive approach for asthma patients with AR.
Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: Damayanti, T., Anggraini, D., Liza, F., Wiyono, W. Tags: Allergy and immunology Source Type: research

Comparison of steroid ‐releasing stents vs nonabsorbable packing as middle meatal spacers
ConclusionIn this study, nonabsorbable packing materials showed significant superior middle meatal spacing capacities as evidenced by greater middle turbinate medialization capability at the first postoperative visit. Additionally, patients with this type of packing saw improvements in their SNOT ‐22 scores at the 20‐day postoperative visit. This study showed that there was no significant improvement in postoperative outcomes with drug‐eluting stents when compared to nonabsorbable packing.
Source: International Forum of Allergy and Rhinology - November 18, 2019 Category: Allergy & Immunology Authors: Jordan W. Rawl, Robert A. McQuitty, Mashfee H. Khan, Lara K. Reichert, Yong ‐Fang Kuo, Mohamad R. Chaaban Tags: ORIGINAL ARTICLE Source Type: research

M302 development of ige mediated milk allergy post 4-food elimination in a patient with eosinophilic esophagitis
Patient is a 9-year-old male with a history of moderate/severe atopic dermatitis, allergic rhinitis and eosinophilic esophagitis (EoE). He initially presented to an outside gastroenterologist at 3 years of age due to poor growth and picky eating. He had an endoscopy performed, which demonstrated esophageal eosinophilia. At the time of EoE diagnosis, patient was without IgE mediated food allergies, specifically tolerating dairy products regularly without symptoms. His initial management of eosinophilic esophagitis included the 4-food elimination diet.
Source: Annals of Allergy, Asthma and Immunology - October 31, 2019 Category: Allergy & Immunology Authors: T. Sarin Source Type: research

M175 omalizumab prophylaxis for endoscopy-associated dermographism
Symptomatic dermographism is an inducible form of urticaria that is often difficult to treat. In antihistamine refractory symptomatic dermographism, omalizumab has demonstrated to be efficacious in case reports.
Source: Annals of Allergy, Asthma and Immunology - October 31, 2019 Category: Allergy & Immunology Authors: W. Blackwell, D. Khan Source Type: research

Predictors of efficacy for combination oral and topical corticosteroids to treat patients with chronic rhinosinusitis with nasal polyps
ConclusionIn treatment of CRSwNP with prednisone and budesonide irrigations, pretreatment endoscopy was not informative of treatment response. Pretreatment SNOT ‐22 and comorbid asthma may be more predictive.
Source: International Forum of Allergy and Rhinology - October 13, 2019 Category: Allergy & Immunology Authors: Madison V. Epperson, Katie M. Phillips, David S. Caradonna, Stacey T. Gray, Ahmad R. Sedaghat Tags: ORIGINAL ARTICLE Source Type: research

Can an otorhinolaryngological visit induce the suspect of allergic rhinitis in children?
In conclusion this real-life study showed that during an ORL visit it is possible to suspect AR in children with turbinate hypertrophy, familial atopy, nasal pale mucosa, adenoid enlargement, and asthma comorbidity. PMID: 31594289 [PubMed - as supplied by publisher]
Source: European Annals of Allergy and Clinical Immunology - October 10, 2019 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Odontogenic sinusitis is a common cause of unilateral sinus disease with maxillary sinus opacification
ConclusionODS caused nearly 50% of all USD cases with maxillary sinus opacification on CT, and was the most common individual etiology. ODS was frequently associated with anterior ethmoid and frontal sinus disease on CT, and middle meatal purulence on nasal endoscopy.
Source: International Forum of Allergy and Rhinology - September 16, 2019 Category: Allergy & Immunology Authors: Zaahir Turfe, Abid Ahmad, Edward I. Peterson, John R. Craig Tags: ORIGINAL ARTICLE Source Type: research

Chronic Rhinosinusitis with Nasal Polyps in Older Adults: Clinical Presentation, Pathophysiology, and Comorbidity
AbstractPurpose of ReviewChronic rhinosinusitis and nasal polyps (CRSwNP) is a common condition that significantly affects patients ’ life. This work aims to provide an up-to-date overview of CRSwNP in older adults, focusing on its aging-related clinical presentations, pathophysiology, and comorbidity associations including asthma.Recent FindingsRecent large population-based studies using nasal endoscopy have shown that CRSwNP is a mostly late-onset disease. Age-related changes in physiologic functions, including nasal epithelial barrier dysfunction, may underlie the incidence and different clinical presentations of CRSw...
Source: Current Allergy and Asthma Reports - September 4, 2019 Category: Allergy & Immunology Source Type: research

Sublingual immunotherapy and omalizumab cured allergic chronic rhinosinusitis and asthma: coincidence or synergistic effect?
A 21-year-old man with chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP) and comorbid asthma the last ten years was referred for allergy evaluation. The diagnosis of CRSwNP was based on the patient ’s symptomatology (nasal congestion, atypical facial pain, hyposmia/anosmia), nasal endoscopy, and the objective evidence of mucosal inflammation (complete opacification of the paranasal sinuses on CT-scan that revealed marked mucosal thickening with partial opacification of right maxillary sinus, near complete opacification of left maxillary sinus, and complete opacification of right and left frontal and anterior ethmoi...
Source: Annals of Allergy, Asthma and Immunology - August 20, 2019 Category: Allergy & Immunology Authors: George N. Konstantinou, Elisavet Kaitalidou, Nikos Skoulikaris Tags: Challenging Clinical Cases Source Type: research

Sinus irrigation penetration after balloon sinuplasty vs functional endoscopic sinus surgery in a cadaveric model
ConclusionIrrigation improved in all sinuses following balloon sinuplasty and FESS. There was further improvement to the maxillary sinus after FESS; however, there was no difference in irrigation to the frontal sinuses following FESS compared to balloon sinuplasty. Extended frontal sinus approaches such as the Modified Lothrop procedure should be considered if more extensive access for irrigation is required.
Source: International Forum of Allergy and Rhinology - July 22, 2019 Category: Allergy & Immunology Authors: Oliver Gantz, Arman Danielian, Alison Yu, Elisabeth H. Ference, Edward C. Kuan, Bozena Wrobel Tags: ORIGINAL ARTICLE Source Type: research

Eosinophilic esophagitis during sublingual and oral allergen immunotherapy
Purpose of review The aim of this review is to discuss the current evidence regarding the development of eosinophilic esophagitis (EoE) in individuals undergoing oral and sublingual immunotherapy (SLIT) for both food and environmental allergens. Cumulative incidence of EoE in patients on allergen immunotherapy for peanut, milk, and egg is estimated. Recent findings De novo development of EoE in patients undergoing oral and SLIT has been demonstrated on the scale of case reports and prospective randomized trials. However, few individuals with EoE-like symptoms during immunotherapy undergo endoscopy, and the long-term o...
Source: Current Opinion in Allergy and Clinical Immunology - June 27, 2019 Category: Allergy & Immunology Tags: PHARMACOTHERAPY AND EVIDENCE BASED MEDICINE: Edited by Enrico Compalati and Ignacio J. Ansotegui Source Type: research

Long ‐term outcomes of endoscopic sinus surgery in the management of adult chronic rhinosinusitis
ConclusionsTen ‐year prospective outcomes of ESS for CRS demonstrate that the initial clinically significant improvements in QOL seen 6 months postoperatively are durable over the long term. Over 75% of patients reported clinically significant long‐term QOL and HUV improvement. HUV returned to normal. Revision surgery rate was 17% and worse postoperative endoscopy scores within 18 months of initial ESS were associated with higher likelihood of revision surgery. Most patients would pursue ESS again and recommend the procedure to other patients considering this treatment option.
Source: International Forum of Allergy and Rhinology - June 16, 2019 Category: Allergy & Immunology Authors: Timothy L. Smith, Rodney J. Schlosser, Jess C. Mace, Jeremiah A. Alt, Daniel M. Beswick, Adam S. DeConde, Kara Y. Detwiller, Jose L. Mattos, Zachary M. Soler Tags: ORIGINAL ARTICLE Source Type: research

Minimally symptomatic patients with eosinophilic esophagitis should still be actively treated-CON
To frame the reader's mind on the topic discussed in this article, I would like to start by presenting a hypothetical (or not so hypothetical) patient case. A 12-year-old boy presents with abdominal pain and nausea and occasional vomiting for the past year. He is seen by a gastroenterology specialist, who performs an upper endoscopy that reveals linear furrowing of the esophagus and 50 eosinophils per high-power field in the proximal esophagus and 40 eosinophils per high-power field in the distal esophagus.
Source: Annals of Allergy, Asthma and Immunology - May 31, 2019 Category: Allergy & Immunology Authors: Jay Adam Lieberman Tags: Pro/Con Debates Source Type: research