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Drug: Aspirin

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Total 985 results found since Jan 2013.

The chronic rhinosinusitis practice parameter
Ann Allergy Asthma Immunol. 2023 Sep;131(3):307-310. doi: 10.1016/j.anai.2022.12.022. Epub 2022 Dec 17.ABSTRACTThe Allergy-Immunology Joint Task Force on Practice Parameters has published the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) guidelines for the medical management of chronic rhinosinusitis with nasal polyposis (CRSwNP). The practice parameter provides evidence-based guidelines on the use of intranasal corticosteroids (INCS) and biologics for CRSwNP, and aspirin therapy after desensitization (ATAD) for the management of aspirin-exacerbated respiratory disease (AERD). Evidence on surge...
Source: Annals of Allergy, Asthma and Immunology - September 5, 2023 Category: Allergy & Immunology Authors: So Lim Kim Matthew A Rank Anju Tripathi Peters Source Type: research

Respiratory Exposure Tests in Aspirin Exacerbated Respiratory Disease
AbstractPurpose of reviewControlled oral provocation test with aspirin is considered the “gold standard” for diagnosing hypersensitivity to NSAIDs (non-steroid anti-inflammatory drugs). Newer techniques of respiratory exposure tests, bronchial and nasal respectively, have been nonetheless developed, as they are safer, less likely to cause a systemic reaction, and less time-consuming than the oral provocation test with aspirin (acetyl-salicylic acid). These tests are also particularly useful when oral challenge testing is contraindicated. The aim of this paper is to review and update the detailed protocols of bronchial ...
Source: Current Treatment Options in Allergy - August 30, 2023 Category: Allergy & Immunology Source Type: research

Use of nonsteroidal anti ‐inflammatory drugs and poor olfaction in women
ConclusionLong-term regular use of aspirin or ibuprofen was associated with poor olfaction among women who never regularly used other types of NSAIDs. These preliminary findings warrant independent confirmation.
Source: International Forum of Allergy and Rhinology - August 8, 2023 Category: Allergy & Immunology Authors: Keran W. Chamberlin, Chenxi Li, Zhehui Luo, Aimee A. D'Aloisio, Jayant M. Pinto, Dale P. Sandler, Honglei Chen Tags: ORIGINAL ARTICLE Source Type: research

Long-term efficacy of anti-IL-4 receptor antibody in a patient with aspirin-exacerbated respiratory disease and IgG4-related disease
Aspirin-exacerbated respiratory disease (AERD) and IgG4-related disease (IgG4RD) share a common pathway of Th2-mediated immune mechanism; there have been several cases of IgG4RD developed in patients with asth...
Source: Allergy, Asthma and Clinical Immunology - August 5, 2023 Category: Allergy & Immunology Authors: Hyun-Seob Jeon, Jae-Hyuk Jang, Youngsoo Lee and Hae-Sim Park Tags: Case report Source Type: research

Lower serum 15-HETE level predicts nasal ILC2 accumulation during COX-1 inhibition in AERD
Aspirin-exacerbated respiratory disease (AERD) is associated with high levels of cysteinyl leukotrienes, prostaglandin D2, and low levels of prostaglandin E2. Further, 15-hydroxyeicosatetraenoic acid (15-HETE) levels may have predictive value in therapeutic outcomes of aspirin desensitization. Accumulation of nasal group 2 innate lymphoid cells (ILC2s) has been demonstrated during COX-1 inhibition in AERD, although the relationships between tissue ILC2 accumulation, reaction symptom severity, and novel lipid biomarkers are unknown.
Source: Journal of Allergy and Clinical Immunology - August 2, 2023 Category: Allergy & Immunology Authors: Jana H. Badrani, Kellen Cavagnero, Jacqueline J. Eastman, Alex S. Kim, Allyssa Strohm, Carol Yan, Adam Deconde, Bruce L. Zuraw, Andrew A. White, Sandra C. Christiansen, Taylor A. Doherty Tags: Brief report Source Type: research

Lower serum 15-HETE predicts nasal ILC2 accumulation during COX-1 inhibition in AERD
Aspirin exacerbated respiratory disease (AERD) is associated with high levels of cysteinyl leukotrienes, prostaglandin D2 (PGD2), and low levels of prostaglandin E2 (PGE2). Further, 15-hydroxyeicosatetraenoic acid (15-HETE) levels may have predictive value in aspirin desensitization therapeutic outcomes. Accumulation of nasal group 2 innate lymphoid cells (ILC2s) has been demonstrated during COX-1 inhibition in AERD though the relationships between tissue ILC2 accumulation, reaction symptom severity, and novel lipid biomarkers is unknown.
Source: Journal of Allergy and Clinical Immunology - August 2, 2023 Category: Allergy & Immunology Authors: Jana H. Badrani, Kellen Cavagnero, Jacqueline J. Eastman, Alex S. Kim, Allyssa Strohm, Carol Yan, Adam Deconde, Bruce L. Zuraw, Andrew A. White, Sandra C. Christiansen, Taylor A. Doherty Source Type: research

Optimizing the timing of biologic and surgical therapy for patients with refractory chronic rhinosinusitis with nasal polyposis (CRSwNP)
ConclusionIn CRSwNP patients, combined ESS and biologic therapy results in a significant and sustained decrease in polyp burden compared to biologic therapy alone. Larger studies are warranted to further examine the impact of combined therapy.This article is protected by copyright. All rights reserved
Source: International Forum of Allergy and Rhinology - July 28, 2023 Category: Allergy & Immunology Authors: Emily Garvey, Bita Naimi, Alexander Duffy, Paavali Hannikainen, Chase Kahn, Douglas Farquhar, Marc Rosen, Mindy Rabinowitz, Elina Toskala, Gurston Nyquist Tags: ORIGINAL ARTICLE Source Type: research

Eosinophilic Granulomatosis with Polyangiitis Presenting as Aspirin Exacerbated Respiratory Disease
Ann Allergy Asthma Immunol. 2023 Jul 22:S1081-1206(23)00519-7. doi: 10.1016/j.anai.2023.07.014. Online ahead of print.NO ABSTRACTPMID:37487803 | DOI:10.1016/j.anai.2023.07.014
Source: Annals of Allergy, Asthma and Immunology - July 24, 2023 Category: Allergy & Immunology Authors: Sabrina D Herzberg Alyssa M Bosso Neel R Sangal John V Bosso Source Type: research

Eosinophilic granulomatosis with polyangiitis presenting as aspirin –exacerbated respiratory disease
Eosinophilic granulomatosis with polyangiitis (EGPA) is a multisystem disorder causing granulomatous inflammation of both small- and medium-sized arteries with hypereosinophilia and eosinophilic systemic tissue infiltration. EGPA can involve the lungs, sinuses, kidneys, heart, nervous system, intestinal tract, or skin.1 Onset is usually between the third and fifth decades of life with the following 3 stages: the prodromal stage with atopic diseases, that is, allergic rhinitis and asthma; the eosinophilic stage where organs become infiltrated with eosinophils and peripheral blood hypereosinophilia; and the final vasculitic ...
Source: Annals of Allergy, Asthma and Immunology - July 22, 2023 Category: Allergy & Immunology Authors: Sabrina D. Herzberg, Alyssa M. Bosso, Neel R. Sangal, John V. Bosso Tags: Letters Source Type: research

The Effect of Corticosteroids on Sinus Microbiota in Chronic Rhinosinusitis Patients with Nasal Polyposis
CONCLUSION: In this pilot study, both treatment options were effective to improve symptoms in the short-term but not in the long-term, and were not linked to any clear sinus microbiota response. As a result, this study supports the avoidance of systemic antibiotics without evidence of active infection.PMID:37475202 | DOI:10.1177/19458924231183848
Source: American Journal of Rhinology and Allergy - July 21, 2023 Category: ENT & OMF Authors: Yousif Alammar Simon Rousseau Martin Desrosiers Marc A Tewfik Source Type: research