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Total 2124 results found since Jan 2013.

Maternal atopic conditions and autism spectrum disorder: a systematic review
The objective of this study is to systematically review observational studies that investigate whether a maternal history of atopic disease (asthma, allergy, or eczema/atopic dermatitis) is associated with a diagnosis of ASD in offspring. A search was conducted in Ovid MEDLINE, PsycINFO, and Embase databases for relevant articles up to November 2021; this was later updated in January 2022. Observational studies published in peer-reviewed journals were included. Data were synthesized an d qualitatively analyzed according to the specific atopic condition. Quality assessment was done using the Newcastle–Ottawa Scale. Nine a...
Source: European Child and Adolescent Psychiatry - September 3, 2023 Category: Psychiatry Source Type: research

FDA Approves First RSV Vaccine for Pregnancy FDA Approves First RSV Vaccine for Pregnancy
The vaccine can be given after 32 weeks of pregnancy and is designed to protect infants from respiratory syncytial virus from birth to 6 months of age.Medscape Medical News
Source: Medscape Allergy Headlines - August 23, 2023 Category: Allergy & Immunology Tags: Infectious Diseases News Alert Source Type: news

The influence of air pollution on gestational age at delivery and birthweight in patients with or without respiratory allergy: A nested case –control study
ConclusionsAir pollutant concentrations, especially SO2, negatively influenced birthweight. The impact of this association was much stronger and more relevant in the group of women with respiratory allergies.
Source: Acta Obstetricia et Gynecologica Scandinavica - August 21, 2023 Category: OBGYN Authors: Irene Bartha, Miguel De  La Fuente, Nuria Martinez‐Sanchez, María De La Calle, Elena Martin Boado, José Luis Bartha Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Maternal vitamin D –related metabolome and offspring risk of asthma outcomes
Vitamin D deficiency in childhood has been associated with various adverse health consequences as 25-hydroxyvitamin D (25(OH)D) possesses a range of immune regulatory properties with potential implications for proneness to respiratory infection, allergies, and asthma.1,2 Studies have further shown that 25(OH)D deficiency during pregnancy may affect fetal immune programming, consequently increasing the risk of asthma in early childhood.3,4 Therefore, we recently performed an intervention study in the Copenhagen Prospective Studies on Asthma in Childhood 2010 (COPSAC2010) cohort,5 which showed beneficial effects of high-dose...
Source: Journal of Allergy and Clinical Immunology - August 7, 2023 Category: Allergy & Immunology Authors: Min Kim, Nicklas Brustad, Mina Ali, G özde Gürdeniz, Morten Arendt, Augusto A. Litonjua, Craig E. Wheelock, Rachel S. Kelly, Yulu Chen, Nicole Prince, Feng Guo, Xiaobo Zhou, Jakob Stokholm, Klaus Bønnelykke, Scott T. Weiss, Hans Bisgaard, Jessica Lasky Source Type: research

Maternal vitamin D-related metabolome and offspring risk of asthma outcomes
In two independent birth cohorts, high-does vitamin D exposure during pregnancy reduced a risk of developing recurrent wheeze and acute wheeze exacerbations in offspring via sphingomyelin enriched metabolic profile.
Source: Journal of Allergy and Clinical Immunology - August 7, 2023 Category: Allergy & Immunology Authors: Min Kim, Nicklas Brustad, Mina Ali, G özde Gürdeniz, Morten Arendt, Augusto A. Litonjua, Craig E. Wheelock, Rachel S. Kelly, Yulu Chen, Nicole Prince, Feng Guo, Xiaobo Zhou, Jakob Stokholm, Klaus Bønnelykke, Scott T. Weiss, Hans Bisgaard, Jessica Lasky Source Type: research

Evidence-based use of antihistamines for treatment of allergic conditions
Ann Allergy Asthma Immunol. 2023 Jul 28:S1081-1206(23)00524-0. doi: 10.1016/j.anai.2023.07.019. Online ahead of print.ABSTRACTAvailable since the 1940s, H1-antihistamines are mainstay treatments for allergic conditions such as allergic rhinitis and urticaria. They function as inverse agonists that bind to the H1 receptor to inhibit histamine-induced inflammation. The older, first-generation drugs are no longer recommended for patient use due to their well documented negative side effect profile. Evidence has been accumulating to support a newer generation of H1-antihistamines in oral and intranasal formulations, including ...
Source: Annals of Allergy, Asthma and Immunology - July 30, 2023 Category: Allergy & Immunology Authors: Sophia Linton Lubnaa Hossenbaccus Anne K Ellis Source Type: research

Di(2-ethylhexyl) phthalate mediates IL-33 production via aryl hydrocarbon receptor and is associated with childhood allergy development
ConclusionsCord blood IL-33 level was correlated to childhood allergy and associated with maternal DEHP exposure. IL-33 might be a potential target to assess the development of DEHP-related childhood allergic disease. Flavonoids might be the natural antidotes for DEHP.
Source: Frontiers in Immunology - July 21, 2023 Category: Allergy & Immunology Source Type: research

Primary Prevention of Allergy - Is It Feasible?
Allergy Asthma Immunol Res. 2023 Jul;15(4):419-436. doi: 10.4168/aair.2023.15.4.419.ABSTRACTThe allergy epidemic has been attributed to environmental influences related to urbanization and the modern lifestyle. In this regard, various theories exploring the role of microbes (hygiene, old friends, microbiota, and biodiversity hypotheses), and the epithelial barrier (epithelial, dual allergen exposure and vitamin D hypotheses) have been proposed. These hypotheses have guided clinical studies that led to the formulation of intervention strategies during the proposed window of opportunity dubbed as the "first thousand days." T...
Source: Allergy, Asthma and Immunology Research - July 20, 2023 Category: Allergy & Immunology Authors: Pauline Poh-Lin Chan Ng Elizabeth Huiwen Tham Bee-Wah Lee Source Type: research