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Total 2124 results found since Jan 2013.
Primary Prevention of Allergy - Is It Feasible?
Allergy Asthma Immunol Res. 2023 Jul;15(4):419-436. doi: 10.4168/aair.2023.15.4.419.ABSTRACTThe allergy epidemic has been attributed to environmental influences related to urbanization and the modern lifestyle. In this regard, various theories exploring the role of microbes (hygiene, old friends, microbiota, and biodiversity hypotheses), and the epithelial barrier (epithelial, dual allergen exposure and vitamin D hypotheses) have been proposed. These hypotheses have guided clinical studies that led to the formulation of intervention strategies during the proposed window of opportunity dubbed as the "first thousand days." T...
Source: Allergy, Asthma and Immunology Research - July 20, 2023 Category: Allergy & Immunology Authors: Pauline Poh-Lin Chan Ng Elizabeth Huiwen Tham Bee-Wah Lee Source Type: research
Association of endocrine disrupting chemicals exposure with human chorionic gonadotropin concentrations in pregnancy
DISCUSSION: Higher exposure to several EDCs during pregnancy was associated with a lower hCG; and despite the small effect sizes, still indicating that the exposure may negatively affect production or secretion of hCG by the placenta. Our results provide the impetus for future experimental studies to investigate the placenta as a target organ for adverse effects of EDCs.PMID:37459690 | DOI:10.1016/j.envint.2023.108091
Source: Environment International - July 17, 2023 Category: Environmental Health Authors: Arash Derakhshan Huan Shu Maarten A C Broeren Andreas Kortenkamp Christian H Lindh Barbara Demeneix Robin P Peeters Carl-Gustaf Bornehag Tim I M Korevaar Source Type: research
Pharmacological Action of Baicalin on Gestational Diabetes Mellitus in Pregnant Animals Induced by Streptozotocin via AGE-RAGE Signaling Pathway
CONCLUSION: Baicalin demonstrated the potential impact on the embryo's development via the AGE-RAGE signaling pathway in STZ-induced GDM pregnant animals.PMID:37436545 | DOI:10.1007/s12010-023-04586-8
Source: Applied Biochemistry and Biotechnology - July 12, 2023 Category: Biochemistry Authors: Shuqiong Qiu Xiaojie Wu Qingke Wu Xin Jin Huirong Li Rupak Roy Source Type: research
Antibiotic use during pregnancy is linked to offspring gut microbial dysbiosis, barrier disruption, and altered immunity along the gut-lung axis
Eur J Immunol. 2023 Jul 10:e2350394. doi: 10.1002/eji.202350394. Online ahead of print.ABSTRACTAntibiotic use during pregnancy is associated with increased asthma risk in children. Since approximately 25% of women use antibiotics during pregnancy, it is important to identify the pathways involved in this phenomenon. We investigate how mother-to-offspring transfer of antibiotic-induced gut microbial dysbiosis influences immune system development along the gut-lung axis. Using a mouse model of maternal antibiotic exposure during pregnancy, we immunophenotyped offspring in early life and after asthma induction. In early life,...
Source: European Journal of Immunology - July 11, 2023 Category: Allergy & Immunology Authors: Moumen M Alhasan Oliver H ölsken Claudia Duerr Sofia Helfrich Nora Branzk Alina Philipp Dominik Leitz Julia Duerr Yahia Almousa Gabriela Barrientos William W Mohn Stefanie Gamradt Melanie L Conrad Source Type: research
