Filtered By:
Condition: Pregnancy
This page shows you your search results in order of date. This is page number 5.
Order by Relevance | Date
Total 2124 results found since Jan 2013.
Antibiotic use during pregnancy is linked to offspring gut microbial dysbiosis, barrier disruption, and altered immunity along the gut-lung axis
Eur J Immunol. 2023 Jul 10:e2350394. doi: 10.1002/eji.202350394. Online ahead of print.ABSTRACTAntibiotic use during pregnancy is associated with increased asthma risk in children. Since approximately 25% of women use antibiotics during pregnancy, it is important to identify the pathways involved in this phenomenon. We investigate how mother-to-offspring transfer of antibiotic-induced gut microbial dysbiosis influences immune system development along the gut-lung axis. Using a mouse model of maternal antibiotic exposure during pregnancy, we immunophenotyped offspring in early life and after asthma induction. In early life,...
Source: European Journal of Immunology - July 11, 2023 Category: Allergy & Immunology Authors: Moumen M Alhasan Oliver H ölsken Claudia Duerr Sofia Helfrich Nora Branzk Alina Philipp Dominik Leitz Julia Duerr Yahia Almousa Gabriela Barrientos William W Mohn Stefanie Gamradt Melanie L Conrad Source Type: research
Associations of gestational and early-life exposure to toxic metals and fluoride with a diagnosis of food allergy or atopic eczema at 1 year of age
In conclusion, our results indicate that gestational cadmium exposure might be associated with food allergy at 1 year of age and, possibly, early-life exposure to fluoride with atopic eczema. Further prospective and mechanistic studies are needed to establish causality.PMID:37422976 | DOI:10.1016/j.envint.2023.108071
Source: Environment International - July 9, 2023 Category: Environmental Health Authors: Mariza Kampouri Klara Gustin Mia Str åvik Malin Barman Anna Sandin Ann-Sofie Sandberg Agnes E Wold Marie Vahter Maria Kippler Source Type: research
Pharmacological Studies on the Ca < sup > 2+ < /sup > Influx Pathways in Platelet-Activating Factor (PAF)-Induced Mouse Urinary Bladder Smooth Muscle Contraction
In this study, we examined the Ca2+ influx pathways involved in PAF-induced BTI and OC in the mouse UBSM. PAF (10-6 M) induced BTI and OC in mouse UBSM. However, the PAF-induced BTI and OC were completely suppressed by extracellular Ca2+ removal. PAF-induced BTI and OC frequencies were markedly suppressed by voltage-dependent Ca2+ channel (VDCC) inhibitors (verapamil (10-5 M), diltiazem (10-5 M), and nifedipine (10-7 M)). However, these VDCC inhibitors had a minor effect on the PAF-induced OC amplitude. The PAF-induced OC amplitude in the presence of verapamil (10-5 M) was strongly suppressed by SKF-96365 (3 × 10-5 M), an...
Source: Biological and Pharmaceutical Bulletin - July 2, 2023 Category: Drugs & Pharmacology Authors: Ge Liu Keisuke Obara Kento Yoshioka Yoshio Tanaka Source Type: research
Pregnant Patients with a Documented History of Penicillin Allergy and Associated Maternal and Neonatal Outcomes at a Tertiary Care Center
Conclusion Pregnant patients who are labeled as having a penicillin allergy are more likely to have postpartum endometritis, and neonates born to mothers who are labeled as having a penicillin allergy are more likely to have a postnatal hospital stay lasting more than 72 hours. There were no other significant differences seen in pregnant patients and their newborns whether they were labeled as having a penicillin allergy history or not. However, pregnant individuals with a penicillin allergy documented in their medical record were significantly more likely to receive alternative non-β lactam antibiotics, and may have ...
Source: American Journal of Perinatology - June 19, 2023 Category: Perinatology & Neonatology Authors: Azmy, Veronica Lundsberg, Lisbet S. Culhane, Jennifer Kwah, Jason Partridge, Caitlin Son, Moeun Tags: Original Article Source Type: research
Prenatal exposure to phthalates and gender-specific play behavior at seven years of age in the SELMA study
CONCLUSION: Our findings suggest associations of prenatal exposure to DINP with decreased masculine play behavior in boys while the results for girls were not fully conclusive.PMID:37331180 | DOI:10.1016/j.envint.2023.108029
Source: Environment International - June 18, 2023 Category: Environmental Health Authors: Fatih Özel Marlene Stratmann Christian Lindh Chris Gennings Carl-Gustaf Bornehag Jo ëlle Rüegg Source Type: research
How to Stay Safe From Wildfire Smoke
This week, many people who live in the U.S. have woken up to hazy skies. Wildfire smoke from Eastern Canada continues to trail down the East Coast and as far west as Minnesota. State and local authorities have issued air-quality warnings throughout the affected regions, and it could be days before they’re lifted.
Wildfire pollution may be a new threat to some of these regions, but with global temperatures climbing, it could be more common in the future. Here’s what to know about staying safe until the smoke clears.
[time-brightcove not-tgx=”true”]
Adjust your day if you’re most at risk
Becau...
Source: TIME: Health - June 7, 2023 Category: Consumer Health News Authors: Haley Weiss Tags: Uncategorized healthscienceclimate Public Health Source Type: news
FDA Approves Pfizer ’ s New RSV Vaccine for Older Adults
After decades of having no vaccines to fight respiratory syncytial respiratory (RSV), the U.S. now has two—both aimed at protecting older adults.
On May 31, the U.S. Food and Drug Administration (FDA) approved the second RSV vaccine in the world. The first, from the pharmaceutical company GSK, gained FDA approval earlier in May for adults age 60 and older. The newest vaccine, made by Pfizer, will also target people in the same age group.
RSV causes respiratory disease that can affect everyone, but elderly adults and young babies typically experience the most severe illness. Between 60,000 and 160,000 American seniors...
Source: TIME: Health - May 31, 2023 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized Drugs healthscienceclimate Source Type: news
Antibiotic choice for Group B Streptococcus prophylaxis in mothers with reported penicillin allergy and associated newborn outcomes
To evaluate the choice of antibiotic used for intrapartum Group B Streptococcus (GBS) prophylaxis in pregnant individuals with reported penicillin allergies compared to those without reported penicillin allerg...
Source: BMC Pregnancy and Childbirth - May 30, 2023 Category: OBGYN Authors: Josephine B. Snider, Leena B. Mithal, Jason H. Kwah, Nathaniel J. Rhodes and Moeun Son Tags: Research Source Type: research
Pregnancy in Primary Immunodeficiency Diseases: the PREPI Study
– Primary immunodeficiencies (PID) are a heterogeneous group of rare inborn immunity defects. As management has greatly improved, morbi-mortality is reduced in this population, while our knowledge on pregnancy unfolding and outcome remains scarce.
Source: Journal of Allergy and Clinical Immunology - May 18, 2023 Category: Allergy & Immunology Authors: Elise Mallart, Ugo Fran çoise, Marine Driessen, Stéphane Blanche, Olivier Lortholary, Agnès Lefort, Marion Caseris, Alain Fischer, Nizar Mahlaoui, Caroline Charlier, for the PREPI study group Source Type: research
Why It Took So Long to Finally Get an RSV Vaccine
Respiratory syncytial virus (RSV) can dangerously compromise breathing, especially for infants and the elderly. But there has been no vaccine to prevent it—until today. On May 3, the U.S. Food and Drug Administration (FDA) approved the first vaccine against RSV, from GlaxoSmithKline (GSK), to prevent respiratory disease in people ages 60 and older. The Centers for Disease Control’s vaccine committee will make formal recommendations in June about who should receive the vaccine, but GSK says it currently has enough doses to vaccinate eligible people beginning this fall.
In studies involving 25,000 people that GSK...
Source: TIME: Health - May 3, 2023 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized Drugs healthscienceclimate Source Type: news
Association between prenatal antimicrobial use and offspring attention deficit hyperactivity disorder
ConclusionsMaternal prenatal antifungal use and frequent prenatal antibiotic use are associated with an increased risk of ADHD in offspring at age 10. These findings highlight the importance of the prenatal environment and the need for careful use of antimicrobials.
Source: PLoS One - May 3, 2023 Category: Biomedical Science Authors: Jennifer K. Straughen Source Type: research
Over 90% of Childhood BCG Vaccine-Induced Keloids in Japan Occur in Women
ConclusionTo our knowledge, this is the largest report in the literature on childhood-onset keloids. There was overall female predominance in childhood-onset keloids, and even more significant female predominance in BCG-induced keloids.
Source: Dermatology and Therapy - May 1, 2023 Category: Dermatology Source Type: research
