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Condition: Pregnancy
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Total 2124 results found since Jan 2013.
Placental Extract and Exosomes Derived from Pregnant Mice Attenuate the Development of Experimental Autoimmune Encephalomyelitis
In this study, we assessed the potential therapeutic effects of PE and exosomes obtained from pregnant mice in experimental autoimmune encephalomyelitis (EAE) mouse models. C57BL/6 mice, 8 to 12 weeks of age, were prepared and administered PE, exosomes, and glatiramer acetate (GA), as an FDA-approved treatment for multiple sclerosis (MS), after EAE induction. Thereafter, the therapeutic effects of treatment were evaluated by measuring the clinical courses of the mice as well as determining the number of regulatory T (Treg) cells using flow cytometry, cytokine levels, and microRNA-326 expression via real-time PCR. GA, PE, a...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 14, 2023 Category: Allergy & Immunology Authors: Morteza Motallebnezhad Shirin Taghizadeh Tayebe Aghaie Maryam Azimi Ali-Akbar Salari Mahmoud Bozorgmehr Elahe Safari Reza Falak Mir-Hadi Jazayeri Source Type: research
25 Years of translational research in the Copenhagen Prospective Studies on Asthma in Childhood (COPSAC)
The Copenhagen Prospective Studies on Asthma in Childhood (COPSAC) mother-child cohorts have provided a foundation of 25 years of research on the origins, prevention, and natural history of childhood asthma and related disorders. COPSAC ’s approach is characterized by clinical translational research with longitudinal deep phenotyping and exposure assessments from pregnancy, in combination with multi-omic data layers and embedded randomized controlled trials. One trial showed that fish oil supplementation during pregnancy prevente d childhood asthma and identified pregnant women with the highest benefits from supplementat...
Source: Journal of Allergy and Clinical Immunology - January 14, 2023 Category: Allergy & Immunology Authors: Hans Bisgaard, Bo Chawes, Jakob Stokholm, Marianne Mikkelsen, Ann-Marie Malby Schoos, Klaus B ønnelykke Tags: Review article Source Type: research
Safety and savings from penicillin allergy de-labelling in pregnancy: good stewardship, good cents
Studies have shown that 80-95% of pregnant patients who report a penicillin allergy can be safely de-labelled. A pencillin allergy has been associated with poor obstetric outcomes, low rates of appropriate antibiotic prescribing and additional healthcare system costs. In a cohort of patients in British Columbia, Canada, who underwent penicillin de-labelling in pregnancy we present safety data and calculations of the lifetime savings following de-labelling.
Source: American Journal of Obstetrics and Gynecology - January 13, 2023 Category: OBGYN Authors: Atkinson A, Zhang BY, Mak R, Paquette V, Dionne F, Watt M, Erdle S, Van schalkwyk J, Wong T, Poliquin V, Elwood C Source Type: research
Prevalence and Influencing Factors of Food Allergy in Global Context: A Meta-Analysis
Conclusion: There were geographical differences in the prevalence of FA. Identification and nursing of FA high-risk populations should be strengthened to improve the quality of life.Int Arch Allergy Immunol
Source: International Archives of Allergy and Immunology - January 12, 2023 Category: Allergy & Immunology Source Type: research
Cost of developing and implementing an antepartum penicillin allergy referral program
This study aimed to estimate the cost of developing and implementing our allergy verification program.
Source: American Journal of Obstetrics and Gynecology - January 1, 2023 Category: OBGYN Authors: Martina S. Burn, Xiao Xu, Jane Liao, Jason Kwah, Moeun Son Tags: Oral Concurrent Session 6 - Medical Complications Source Type: research
Allergy evaluation in syphilis positive pregnant individuals with penicillin allergy: A cost effectiveness analysis
In this study, we evaluated allergy evaluation for PCN-allergic, syphilis-positive pregnant individuals as a means to prevent potential anaphylaxis with PCN exposure.
Source: American Journal of Obstetrics and Gynecology - January 1, 2023 Category: OBGYN Authors: Megha Arora, Uma Doshi, Sarina R. Chaiken, Helen Samuel, Aaron B. Caughey Tags: Poster Session I Source Type: research
Allergic maternal inflammation in rats programs offspring oxytocin and vasopressin innervation in social brain regions
Exposure to inflammatory perturbations, such as infection or allergy, during pregnancy increases the offspring ’s risk for neurodevelopmental disorders. Rodent models enable us to investigate the neural mechanisms that may underlie behavioral changes in offspring exposed to inflammation in utero. Our lab has demonstrated that a rat model of allergic maternal immune activation (MIA) induces behavior in offs pring resembling that found in neurodevelopmental disorders, including decreased juvenile social play.
Source: American Journal of Obstetrics and Gynecology - January 1, 2023 Category: OBGYN Authors: Sophia Costantine, Michaela R. Breach, Habib Akouri, Kathryn M. Lenz Tags: Poster Session II Source Type: research
