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Total 2491 results found since Jan 2013.

Prenatal dietary exposure to chemicals and allergy or respiratory diseases in children in the EDEN mother-child cohort
CONCLUSION: Prenatal dietary exposure to chemicals was associated with risk of allergic rhinitis or wheezing up to age 8 y. A few chemicals were associated with other allergic and respiratory diseases. Larger prospective studies are needed to confirm these findings.PMID:37734145 | DOI:10.1016/j.envint.2023.108195
Source: Environment International - September 21, 2023 Category: Environmental Health Authors: Manel Ghozal Manik Kadawathagedara Rosalie Delvert Karine Adel-Patient Muriel Tafflet Isabella Annesi-Maesano Am élie Crépet V éronique Sirot Marie Aline Charles Barbara Heude Blandine de Lauzon-Guillain Source Type: research

Born to wheeze or learned when we were young: maternal and environmental factors influence atopic risk
Trans Am Clin Climatol Assoc. 2023;133:181-192.ABSTRACTThe prevalence of atopic diseases is increasing globally, particularly in children. Heritable genetics can partially explain risk of disease. Evidence also points to acquired genetic material, in the form of the microbiome, as an important factor in disease pathogenesis. The acquisition of the microbiome dynamically changes in response to differences in lifestyle and environmental factors. Also, in utero, maternal and environmental factors influence atopic risk for allergic rhinitis, eczema, asthma, and food allergy. Combining the analytical power of omics, we focus on...
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Authors: Patricia W Finn David L Perkins Source Type: research

Born to wheeze or learned when we were young: maternal and environmental factors influence atopic risk
Trans Am Clin Climatol Assoc. 2023;133:181-192.ABSTRACTThe prevalence of atopic diseases is increasing globally, particularly in children. Heritable genetics can partially explain risk of disease. Evidence also points to acquired genetic material, in the form of the microbiome, as an important factor in disease pathogenesis. The acquisition of the microbiome dynamically changes in response to differences in lifestyle and environmental factors. Also, in utero, maternal and environmental factors influence atopic risk for allergic rhinitis, eczema, asthma, and food allergy. Combining the analytical power of omics, we focus on...
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Authors: Patricia W Finn David L Perkins Source Type: research

Born to wheeze or learned when we were young: maternal and environmental factors influence atopic risk
Trans Am Clin Climatol Assoc. 2023;133:181-192.ABSTRACTThe prevalence of atopic diseases is increasing globally, particularly in children. Heritable genetics can partially explain risk of disease. Evidence also points to acquired genetic material, in the form of the microbiome, as an important factor in disease pathogenesis. The acquisition of the microbiome dynamically changes in response to differences in lifestyle and environmental factors. Also, in utero, maternal and environmental factors influence atopic risk for allergic rhinitis, eczema, asthma, and food allergy. Combining the analytical power of omics, we focus on...
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Authors: Patricia W Finn David L Perkins Source Type: research

Born to wheeze or learned when we were young: maternal and environmental factors influence atopic risk
Trans Am Clin Climatol Assoc. 2023;133:181-192.ABSTRACTThe prevalence of atopic diseases is increasing globally, particularly in children. Heritable genetics can partially explain risk of disease. Evidence also points to acquired genetic material, in the form of the microbiome, as an important factor in disease pathogenesis. The acquisition of the microbiome dynamically changes in response to differences in lifestyle and environmental factors. Also, in utero, maternal and environmental factors influence atopic risk for allergic rhinitis, eczema, asthma, and food allergy. Combining the analytical power of omics, we focus on...
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Authors: Patricia W Finn David L Perkins Source Type: research

Expert opinion on management of moderate-to-severe atopic dermatitis in Qatar
J Dermatolog Treat. 2023 Dec;34(1):2251622. doi: 10.1080/09546634.2023.2251622.ABSTRACTAtopic dermatitis (AD), a chronic-relapsing inflammatory skin disorder, manifests with intense itching and eczematous lesions impairing quality of life. A heterogeneous population, and regional clinical practices for treating AD warrant the development of guidelines in Qatar. Therefore, guidelines for the management of moderate-to-severe AD in Qatar have been developed and discussed. Experts, including dermatologists and immunologists, used the Delphi technique for developing guidelines. Consensus was defined as ≥75% agreement or disag...
Source: Journal of Dermatological Treatment - September 13, 2023 Category: Dermatology Authors: Martin Steinhoff Mehdi Adeli Hassan Riad Mohamed Allam Ahmad Hazem Ra'ed Alsmadi Adel Mohamed Kamal Waad Ibrahim Maryam Ali Al-Nesf Source Type: research

Born to wheeze or learned when we were young: maternal and environmental factors influence atopic risk
Trans Am Clin Climatol Assoc. 2023;133:181-192.ABSTRACTThe prevalence of atopic diseases is increasing globally, particularly in children. Heritable genetics can partially explain risk of disease. Evidence also points to acquired genetic material, in the form of the microbiome, as an important factor in disease pathogenesis. The acquisition of the microbiome dynamically changes in response to differences in lifestyle and environmental factors. Also, in utero, maternal and environmental factors influence atopic risk for allergic rhinitis, eczema, asthma, and food allergy. Combining the analytical power of omics, we focus on...
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Authors: Patricia W Finn David L Perkins Source Type: research

Born to wheeze or learned when we were young: maternal and environmental factors influence atopic risk
Trans Am Clin Climatol Assoc. 2023;133:181-192.ABSTRACTThe prevalence of atopic diseases is increasing globally, particularly in children. Heritable genetics can partially explain risk of disease. Evidence also points to acquired genetic material, in the form of the microbiome, as an important factor in disease pathogenesis. The acquisition of the microbiome dynamically changes in response to differences in lifestyle and environmental factors. Also, in utero, maternal and environmental factors influence atopic risk for allergic rhinitis, eczema, asthma, and food allergy. Combining the analytical power of omics, we focus on...
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Authors: Patricia W Finn David L Perkins Source Type: research

Born to wheeze or learned when we were young: maternal and environmental factors influence atopic risk
Trans Am Clin Climatol Assoc. 2023;133:181-192.ABSTRACTThe prevalence of atopic diseases is increasing globally, particularly in children. Heritable genetics can partially explain risk of disease. Evidence also points to acquired genetic material, in the form of the microbiome, as an important factor in disease pathogenesis. The acquisition of the microbiome dynamically changes in response to differences in lifestyle and environmental factors. Also, in utero, maternal and environmental factors influence atopic risk for allergic rhinitis, eczema, asthma, and food allergy. Combining the analytical power of omics, we focus on...
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Authors: Patricia W Finn David L Perkins Source Type: research

Expert opinion on management of moderate-to-severe atopic dermatitis in Qatar
J Dermatolog Treat. 2023 Dec;34(1):2251622. doi: 10.1080/09546634.2023.2251622.ABSTRACTAtopic dermatitis (AD), a chronic-relapsing inflammatory skin disorder, manifests with intense itching and eczematous lesions impairing quality of life. A heterogeneous population, and regional clinical practices for treating AD warrant the development of guidelines in Qatar. Therefore, guidelines for the management of moderate-to-severe AD in Qatar have been developed and discussed. Experts, including dermatologists and immunologists, used the Delphi technique for developing guidelines. Consensus was defined as ≥75% agreement or disag...
Source: Journal of Dermatological Treatment - September 13, 2023 Category: Dermatology Authors: Martin Steinhoff Mehdi Adeli Hassan Riad Mohamed Allam Ahmad Hazem Ra'ed Alsmadi Adel Mohamed Kamal Waad Ibrahim Maryam Ali Al-Nesf Source Type: research

Topical treatments for atopic dermatitis (eczema): systematic review and network meta-analysis of randomized trials
Source: Journal of Allergy and Clinical Immunology - September 6, 2023 Category: Allergy & Immunology Authors: Derek K. Chu, Alexandro W.L. Chu, Daniel G. Rayner, Gordon H. Guyatt, Juan Jos é Yepes-Nuñez, Luis Gomez-Escobar, Lucia C. Pérez-Herrera, Juan Pablo Díaz Martinez, Romina Brignardello-Petersen, Behnam Sadeghirad, Melanie M. Wong, Renata Ceccacci, Iren Source Type: research

Systemic treatments for atopic dermatitis (eczema): systematic review and network meta-analysis of randomized trials
Source: Journal of Allergy and Clinical Immunology - September 5, 2023 Category: Allergy & Immunology Authors: Alexandro W.L. Chu, Melanie M. Wong, Daniel G. Rayner, Gordon H. Guyatt, Juan Pablo D íaz Martinez, Renata Ceccacci, Irene X. Zhao, Eric McMullen, Archita Srivastava, Jason Wang, Aaron Wen, Fang Chi Wang, Romina Brignardello-Petersen, Ariel Izcovich, Pau Source Type: research

Dupilumab strengthens HSV-1 specific immune responses in atopic dermatitis
CONCLUSION: Our findings suggest that dupilumab may improve the HSV-1-specific immune response in AD due to an increased type I immune response and a reduction of HSV-1-specific IgE.PMID:37660986 | DOI:10.1016/j.jaci.2023.08.024
Source: Herpes - September 3, 2023 Category: Infectious Diseases Authors: Stephan Traidl Leonard Harries Petra Kienlin Gabriele Begemann Lennart M Roesner Thomas Werfel Source Type: research

Maternal atopic conditions and autism spectrum disorder: a systematic review
The objective of this study is to systematically review observational studies that investigate whether a maternal history of atopic disease (asthma, allergy, or eczema/atopic dermatitis) is associated with a diagnosis of ASD in offspring. A search was conducted in Ovid MEDLINE, PsycINFO, and Embase databases for relevant articles up to November 2021; this was later updated in January 2022. Observational studies published in peer-reviewed journals were included. Data were synthesized an d qualitatively analyzed according to the specific atopic condition. Quality assessment was done using the Newcastle–Ottawa Scale. Nine a...
Source: European Child and Adolescent Psychiatry - September 3, 2023 Category: Psychiatry Source Type: research

Dupilumab strengthens HSV-1 specific immune responses in atopic dermatitis
Impaired viral clearance in a subgroup of atopic dermatitis (AD) patients can lead to severe herpes simplex virus (HSV) infections named eczema herpeticum (EH). We recently identified a type 2 skewed viral immune response in EH patients. Clinical data suggest a reduced incidence of EH in AD patients treated with dupilumab, however, immunological investigations of this phenomenon are still lacking.
Source: Journal of Allergy and Clinical Immunology - September 1, 2023 Category: Allergy & Immunology Authors: Stephan Traidl, Leonard Harries, Petra Kienlin, Gabriele Begemann, Lennart M. Roesner, Thomas Werfel Source Type: research