Retraction Note: MicroRNA-93-5p promotes epithelial-mesenchymal transition in gastric cancer by repressing tumor suppressor AHNAK expression
(Source: Cancer Cell International)
Source: Cancer Cell International - April 30, 2024 Category: Cancer & Oncology Authors: Erdong Shen, Xin Wang, Xin Liu, Mingyue Lv, Liang Zhang, Guolian Zhu and Zhe Sun Tags: Retraction Note Source Type: research

Retraction Note: Circular RNA ITCH suppressed prostate cancer progression by increasing HOXB13 expression via spongy miR-17-5p
(Source: Cancer Cell International)
Source: Cancer Cell International - April 30, 2024 Category: Cancer & Oncology Authors: Xuegang Wang, Rong Wang, Zhun Wu and Peide Bai Tags: Retraction Note Source Type: research

Exosome-mediated secretion of miR-127-3p regulated by RAB27A accelerates metastasis in renal cell carcinoma
The exosome-mediated extracellular secretion of miRNAs occurs in many cancers, and RAB27A is a potent regulator of exosome secretion. For metastatic renal cell carcinoma (RCC), this study examines the mechanis... (Source: Cancer Cell International)
Source: Cancer Cell International - April 29, 2024 Category: Cancer & Oncology Authors: Dae Hyun Song, Jong Sil Lee, Jeong-Hee Lee, Dong Chul Kim, Jung Wook Yang, Min Hye Kim, Ji Min Na, Hyun-kyung Cho, Jiyun Yoo and Hyo Jung An Tags: Research Source Type: research

Identification of SUMOylation-related biomarkers in papillary thyroid carcinoma
This study identifies biomarkers linked to SUMOylation in papillary thyroid carcinoma ... (Source: Cancer Cell International)
Source: Cancer Cell International - April 27, 2024 Category: Cancer & Oncology Authors: Xiang Li, Zigang Ding and Yun Tong Tags: Research Source Type: research

Antitumor mechanisms and future clinical applications of the natural product triptolide
Triptolide (TPL) is a compound sourced from Tripterygium wilfordii Hook. F., a traditional Chinese medicinal herb recognized for its impressive anti-inflammatory, anti-angiogenic, immunosuppressive, and antitu... (Source: Cancer Cell International)
Source: Cancer Cell International - April 27, 2024 Category: Cancer & Oncology Authors: Shiwei Bao, Mei Yi, Bo Xiang and Pan Chen Tags: Review Source Type: research

Retraction Note: Circular RNA circ_0000517 regulates hepatocellular carcinoma development via miR-326/IGF1R axis
(Source: Cancer Cell International)
Source: Cancer Cell International - April 27, 2024 Category: Cancer & Oncology Authors: Shuwei He, Jianzeng Yang, Shitao Jiang, Yuan Li and Xingmin Han Tags: Retraction Note Source Type: research

circ-TFRC downregulation suppresses ovarian cancer progression via miR-615-3p/IGF2 axis regulation
Ovarian cancer (OC) is a malignancy among female globally. Circular RNAs (circRNAs) are a family of circular endogenous RNAs generated from selective splicing, which take part in many traits. Former investigat... (Source: Cancer Cell International)
Source: Cancer Cell International - April 27, 2024 Category: Cancer & Oncology Authors: Zhongxin Yan, Changling Duan, Xi Li, Hao Wang, Shanji Li, Xuexin Zhou and Yi Miao Tags: Research Source Type: research

Human P2X7 receptor variants Gly150Arg and Arg276His polymorphisms have differential effects on risk association and cellular functions in pancreatic cancer
The purinergic P2X7 receptor (P2X7R) plays an important role in the crosstalk between pancreatic stellate cells (PSCs) and cancer cells, thus promoting progression of pancreatic ductal adenocarcinoma (PDAC). S... (Source: Cancer Cell International)
Source: Cancer Cell International - April 25, 2024 Category: Cancer & Oncology Authors: Lara Magni, Haoran Yu, Nynne M. Christensen, Mette H. Poulsen, Alexander Frueh, Ganga Deshar, Astrid Z. Johansen, Julia S. Johansen, Stephan A. Pless, Niklas R. J ørgensen and Ivana Novak Tags: Research Source Type: research

CDCA5-EEF1A1 interaction promotes progression of clear cell renal cell carcinoma by regulating mTOR signaling
Cell division cycle associated 5 (CDCA5) plays ontogenetic role in various human cancers. However, its specific function and regulatory mechanism in ccRCC remain uncertain. (Source: Cancer Cell International)
Source: Cancer Cell International - April 24, 2024 Category: Cancer & Oncology Authors: Xun Wang, An Shi, Jie Liu, Wen Kong, Yiran Huang, Wei Xue, Fan Yang and Jiwei Huang Tags: Research Source Type: research

PPP2R1A silencing suppresses LUAD progression by sensitizing cells to nelfinavir-induced apoptosis and pyroptosis
Lung adenocarcinoma is a major public health problem with the low 5-year survival rate (15%) among cancers. Aberrant alterations of meiotic genes, which have gained increased attention recently, might contribu... (Source: Cancer Cell International)
Source: Cancer Cell International - April 23, 2024 Category: Cancer & Oncology Authors: Yating Liu, Lianlian Ouyang, Shiyao Jiang, Lu Liang, Yuanbing Chen, Chao Mao, Yiqun Jiang and Li Cong Tags: Research Source Type: research

C6orf15 promotes liver metastasis via WNT/ β-catenin signalling in colorectal cancer
Colon cancer ranks third among global tumours and second in cancer-related mortality, prompting an urgent need to explore new therapeutic targets. C6orf15 is a novel gene that has been reported only in Sjogren... (Source: Cancer Cell International)
Source: Cancer Cell International - April 23, 2024 Category: Cancer & Oncology Authors: Jiankang Yu, Jian Sun, Jingtong Tang, Jiayu Xu, Guanru Qian and Jianping Zhou Tags: Research Source Type: research

Toxoplasma gondii suppresses proliferation and migration of breast cancer cells by regulating their transcriptome
Breast cancer is the most common cancer in women worldwide. Toxoplasma gondii (T. gondii) has shown anticancer activity in breast cancer mouse models, and exerted beneficial effect on the survival of breast cance... (Source: Cancer Cell International)
Source: Cancer Cell International - April 23, 2024 Category: Cancer & Oncology Authors: Hengming Ye, Xiaotao Zhou, Bike Zhu, Tiantian Xiong, Weile Huang, Feng He, Hui Li, Lihua Chen, Luying Tang and Zefang Ren Tags: Research Source Type: research

Unravelling immune microenvironment features underlying tumor progression in the single-cell era
The relationship between the immune cell and tumor occurrence and progression remains unclear. Profiling alterations in the tumor immune microenvironment (TIME) at high resolution is crucial to identify factor... (Source: Cancer Cell International)
Source: Cancer Cell International - April 22, 2024 Category: Cancer & Oncology Authors: Qilian Du, Qi An, Jiajun Zhang, Chao Liu and Qinyong Hu Tags: Review Source Type: research

High LGALS3 expression induced by HCP5/hsa-miR-27b-3p correlates with poor prognosis and tumor immune infiltration in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is widely recognized for its unfavorable prognosis. Increasing evidence has revealed that LGALS3 has an essential function in initiating and developing several malignancies in hu... (Source: Cancer Cell International)
Source: Cancer Cell International - April 20, 2024 Category: Cancer & Oncology Authors: Yinghui Ren, Yongmei Qian, Qicheng Zhang, Xiaoping Li, Mingjiang Li, Wei Li, Pan Yang, Hengchang Ren, Hongxia Li, Yiqi Weng, Dengwen Li, Ke Xu and Wenli Yu Tags: Research Source Type: research

Sparassis latifolia and exercise training as complementary medicine mitigated the 5-fluorouracil potent side effects in mice with colorectal cancer: bioinformatics approaches, novel monitoring pathological metrics, screening signatures, and innovative management tactic
Prompt identification and assessment of the disease are essential for reducing the death rate associated with colorectal cancer (COL). Identifying specific causal or sensitive components, such as coding RNA (c... (Source: Cancer Cell International)
Source: Cancer Cell International - April 18, 2024 Category: Cancer & Oncology Authors: Navid Abedpoor, Farzaneh Taghian, Khosro Jalali Dehkordi and Kamran Safavi Tags: Research Source Type: research