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Total 101973 results found since Jan 2013.
Male kidney-specific BMAL1 knockout mice are protected from Potassium-deficient, high salt diet-induced blood pressure increases
Am J Physiol Renal Physiol. 2023 Sep 14. doi: 10.1152/ajprenal.00126.2023. Online ahead of print.ABSTRACTThe circadian clock protein BMAL1 is a transcription factor that impacts kidney function, including blood pressure (BP) control. Previously, we showed that male, but not female, kidney-specific cadherin Cre positive BMAL1 knockout mice (KS-BMAL1 KO) exhibit lower BP compared to littermate controls. The goal of this study was to determine the BP phenotype and immune response in male KS-BMAL1 KO in response to a low potassium, high salt diet (LKHS). BP, renal inflammatory markers and immune cells were measured in male mic...
Source: Am J Physiol Renal P... - September 14, 2023 Category: Urology & Nephrology Authors: G Ryan Crislip Hannah M Costello Alexandria Juffre Kit-Yan Cheng I Jeanette Lynch Jermaine G Johnston Charles B Drucker Phillip Bratanatawira Annanya Agarwal Victor M Mendez Ryanne S Thelwell Lauren G Douma Charles S Wingo Abdel A Alli Yogesh M Scindia Mi Source Type: research
Dietary Effects of Selenium Nanoparticles on Growth Performance, Survival Rate, Chemical Composition, and Muscle Bioaccumulation of Nile Tilapia (Oreochromis niloticus)
This study evaluated the effect of selenium nanoparticles on growth performance, survival rate, chemical composition, and bioaccumulation of selenium in the muscle of Nile tilapia (Oreochromis niloticus). Fish with an average weight of 33.1 ± 1.0 g were distributed in 12 fiberglass tanks and fed for 56 days with different levels of selenium nanoparticles, 0, 0.5, 1, and 2 mg/kg of diet, considered as control, T1, T2, and T3, respectively. Body weight increase (BWI), specific growth rate (SGR), and food conversion ratio (FCR) were significantly influenced by 2 mg/kg of selenium nanoparticles compared to the other treatment...
Source: Biological Trace Element Research - September 14, 2023 Category: Biology Authors: Shervin Sheikh Fariborz Ghojaghi Afshin Ghelichi Sarah Jorjani Source Type: research
Idiopathic pulmonary fibrosis (IPF): disease pathophysiology, targets, and potential therapeutic interventions
In this study, we focus on the IPF and COVID-19 pathogenesis and the potential role of Apigenin in addressing disease progression.PMID:37707699 | DOI:10.1007/s11010-023-04845-6
Source: Molecular and Cellular Biochemistry - September 14, 2023 Category: Biochemistry Authors: Pritha Saha Priti Talwar Source Type: research
Exploring diet-induced promoter hypomethylation and PDK4 overexpression: implications for type 2 diabetes mellitus
CONCLUSIONS: These findings suggest that T2DM can be induced by high-carbohydrate and high-MSG diets. However, the sole consumption of high MSG did not lead to the development of T2DM. Further research should focus on conducting long-term studies to fully comprehend the impact of a high MSG diet on individuals with pre-existing T2DM.PMID:37707772 | DOI:10.1007/s11033-023-08794-7
Source: Molecular Biology Reports - September 14, 2023 Category: Molecular Biology Authors: Sulistyo Emantoko Dwi Putra Farizky Martriano Humardani Lisa Thalia Mulyanata Lady Theresa Adeodata Tanaya Heru Wijono Hikmawan Wahyu Sulistomo Dini Kesuma Risma Ikawaty Source Type: research
Isoxanthohumol improves obesity and glucose metabolism via inhibiting intestinal lipid absorption with a bloom of Akkermansia muciniphila in mice
CONCLUSIONS: Our study demonstrated that IX prevents obesity and enhances glucose metabolism by inhibiting dietary fat absorption. This mechanism is linked to suppressing pancreatic lipase activity and shifts in microbial composition, notably an increase in A. muciniphila. These highlight new treatment strategies for preventing metabolic syndrome by boosting the gut microbiota with food components.PMID:37709134 | DOI:10.1016/j.molmet.2023.101797
Source: Molecular Medicine - September 14, 2023 Category: Molecular Biology Authors: Yoshiyuki Watanabe Shiho Fujisaka Yoshitomo Morinaga Shiro Watanabe Allah Nawaz Hideki Hatta Tomonobu Kado Ayumi Nishimura Muhammad Bilal Muhammad Rahil Aslam Keiko Honda Yoshimi Nakagawa Samir Softic Kenichi Hirabayashi Takashi Nakagawa Yoshinori Nagai K Source Type: research
Enrichment of sialic acid-containing casein glycomacropeptide in protein hydrolysates using phenylboronic acid-functionalized mesoporous silica nanoparticles
Talanta. 2023 Sep 9;267:125174. doi: 10.1016/j.talanta.2023.125174. Online ahead of print.ABSTRACTGlycomacropeptide (GMP) is a bioactive peptide of high value, rich in glycosylation sites and with physiological and dietary therapeutic value. The enrichment and detection of GMP facilitates the accurate quantification and the identification of adulteration of GMP in food products. In GMP, sialic acid is an abundant glycosyl group and is mainly located at the end of the sugar chain. Here, we propose a novel GMP enrichment strategy based on the affinity of sialic acid for phenylboronic acid groups that shift with environmental...
Source: Talanta - September 14, 2023 Category: Chemistry Authors: Chenhui Lu Haodong Wei Lizhi Xu Wen-Long Wang Cheng Yang Xueli Shi Hui Gao Yong-Wei Feng Jianzhong Zhou Yi Zhang Source Type: research
Estimating the Jordanian population dietary exposure to pesticides residues: An exploratory deterministic approach
This study uses a deterministic approach as a screening method to determine the population's likelihood of daily dietary exposure to pesticide residues and identify pesticides that require further investigation. We investigated the data from surveillance programs to assess pesticide contamination in food. We also obtained data about the population's estimated consumption of different food items. The daily exposure to pesticide residues through food was estimated with two scenarios (Lu et al., 2006): the lower bound (LB) scenario and (Luo and Zhang, 2009) the upper bound (UB) scenario. The data provided the concentration of...
Source: Food and Chemical Toxicology - September 14, 2023 Category: Food Science Authors: Nour Abdo Muath Y Muheisen Source Type: research
A 90-day feeding study of genetically modi fied maize LP007-1 in wistar han RCC rats
Food Chem Toxicol. 2023 Sep 12:114026. doi: 10.1016/j.fct.2023.114026. Online ahead of print.ABSTRACTLP007-1 is a variety of insect-resistant and herbicide-tolerant maize containing the modified cry1Ab, cry2Ab, vip3Aa and cp4-epsps genes. The food safety assessment of the maize LP007-1 was conducted in Wistar Han RCC rats by a 90-days feeding study. Maize grains from both LP007-1 or its corresponding non-genetically modified control maize AX808 were incorporated into rodent diets at 25% and 50% concentrations by mass and administered to rats (n = 10/sex/group) for 90 days. A commercialized rodent diet was fed to an additi...
Source: Food and Chemical Toxicology - September 14, 2023 Category: Food Science Authors: Qinghong Zhou Shufei Li Miao Zhao Yinghua Liu Ning He Xiaoli Zhou Dianming Zhou Zhiyong Qian Source Type: research
Low concentrations of perfluoroalkyl acids (PFAAs) in municipal drinking water associated with serum PFAA concentrations in Swedish adolescents
In conclusion, PFAA exposure from low-level contaminated DW must be considered in risk assessment for adolescents.PMID:37708812 | DOI:10.1016/j.envint.2023.108166
Source: Environment International - September 14, 2023 Category: Environmental Health Authors: Jennifer Nystr öm-Kandola Lutz Ahrens Anders Glynn Gunnar Johanson Jonathan P Benskin Irina Gyllenhammar Sanna Lignell Carolina Vogs Source Type: research
Factors associated with academic performance in adolescents from La Rioja (Spain): lifestyle habits, health indicators, and sociodemographic factors
CONCLUSIONS: interventions aimed at combating academic failure should take into account the aforementioned associated factors, with special emphasis on the most vulnerable groups such as males, those with lower socioeconomic status, and those who follow unhealthy lifestyle habits.PMID:37705442 | DOI:10.20960/nh.04599
Source: Nutricion Hospitalaria - September 14, 2023 Category: Nutrition Authors: Ra úl Jiménez Boraita Josep Mar ía Dalmau Torres Esther Gargallo Ibort Daniel Arriscado Alsina Source Type: research
Protective effect of dietary micronutrients on gastric cancer risk among Jordanians
CONCLUSIONS: our data support favorable effects of dietary consumption of some vitamins and minerals against GC risk.PMID:37705441 | DOI:10.20960/nh.04547
Source: Nutricion Hospitalaria - September 14, 2023 Category: Nutrition Authors: Sabika Allehdan Shatha S Hammad Razan M Alatrash Tareq Al-Jaberi Ahmad Hushki Shirin Yacoub Mohammad Dahoud Tahra Elobeid Reema Tayyem Tayyem Source Type: research
Effect of various dietary fructose concentrations on the gallstone formation process in mice
CONCLUSION: changes in plasma, liver and bile lipids were only observed at very high fructose concentrations diets. We conclude that fructose apparently does not alter the gallstone formation process in our experimental model.PMID:37705438 | DOI:10.20960/nh.04610
Source: Nutricion Hospitalaria - September 14, 2023 Category: Nutrition Authors: Reginald Del Pozo Iribarren Lorena Mardones Marcelo Villagr án Katia Mu ñoz Luciano Troncoso Maximiliano Mellado Mirna Mu ñoz Source Type: research
Comparative Effectiveness of Behavioral Interventions for Cardiovascular Risk Reduction in Latinos: A Systematic Review
CONCLUSION: Existing evidence is mixed. Future research should assess the effectiveness of understudied treatment modalities (including nurse-led, mobile health, and family-based interventions) in reducing CVD risk in Latinos.PMID:37707966 | DOI:10.1097/JCN.0000000000000806
Source: The Journal of Cardiovascular Nursing - September 14, 2023 Category: Nursing Authors: Leah V Estrada Jasmine Solano Meghan Reading Turchioe Yamnia I Cortes Billy A Caceres Source Type: research
Genetic variants in CD36: emerging role in oral fat perception and food preferences
Nutr Hosp. 2023 Sep 1. doi: 10.20960/nh.04711. Online ahead of print.ABSTRACTCD36 is a receptor involved in physiologic, metabolic and pathologic processes. Due to its affinity for long-chain fatty acids, it has been postulated as a taste receptor of fatty taste. In this review, the emerging genetic evidence linking CD36 to oral fat perception is analyzed. A systematic literature search was conducted in PubMed, published articles from 2000 to 2022 were considered. Multiple studies have shown an association of some genetic variants in CD36 with fat foods preferences and it has been suggested that these variants can modify o...
Source: Nutricion Hospitalaria - September 14, 2023 Category: Nutrition Authors: Mayra Alejandra Enciso Ram írez Zyanya Reyes Castillo Elia Herminia Vald és Miramontes Source Type: research
High Maternal Adiposity During Pregnancy Programs an Imbalance in the Lipidome and Predisposes to Diet-induced Hepatosteatosis in the Offspring
CONCLUSION: High maternal adiposity during pregnancy programs a susceptibility to diet-induced hepatosteatosis.PMID:37706282 | DOI:10.1042/BSR20231060
Source: Bioscience Reports - September 14, 2023 Category: Biomedical Science Authors: Taylor B Scheidl Jessica L Wager Larissa G Baker Amy L Brightwell Katrina M Melan Sebastian Larion Ousseynou Sarr T R Regnault Stefan J Urbanski Jennifer Thompson Source Type: research
