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Vaccination: Vaccines
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Erratum to "Maternal Immunization During the Second Trimester with BNT162b2 mRNA Vaccine Induces a Robust IgA Response in Human Milk: A Prospective Cohort Study" The American Journal of Clinical Nutrition volume 118 (2023) 572-578/Article Number
Am J Clin Nutr. 2023 Sep 14:S0002-9165(23)66126-X. doi: 10.1016/j.ajcnut.2023.09.002. Online ahead of print.NO ABSTRACTPMID:37717944 | DOI:10.1016/j.ajcnut.2023.09.002
Source: Am J Clin Nutr - September 17, 2023 Category: Nutrition Authors: Aya Kigel Sharon Vanetik Laurence Mangel Gal Friedman Chen Nozik Camilla Terracina David Taussig Yael Dror Hadar Samra Dror Mandel Ronit Lubetzky Yariv Wine Source Type: research
Active inoculation with an inactivated Coxsackievirus A2 vaccine induces neutralizing antibodies and protects mice against lethal infection
In conclusion, our findings suggest that this experimental inactivated CVA2 vaccine is a promising component of polyvalent vaccines related to HFMD in the near future.PMID:37718187 | DOI:10.1016/j.vaccine.2023.08.083
Source: Vaccine - September 17, 2023 Category: Allergy & Immunology Authors: Yuexia Wang Wangquan Ji Dong Li Tiantian Sun Peiyu Zhu Junwei Li Liang Zhang Yu Zhang Haiyan Yang Shuaiyin Chen Yuefei Jin Guangcai Duan Source Type: research
Protocol for a living evidence synthesis on variants of concern and COVID-19 vaccine effectiveness
DISCUSSION: Evidence generated from our living evidence synthesis will be used to inform policy making, modelling, and prioritization of future research on the effectiveness of COVID-19 vaccines against VOC.PMID:37718186 | DOI:10.1016/j.vaccine.2023.09.012
Source: Vaccine - September 17, 2023 Category: Allergy & Immunology Authors: Nicole Shaver Melanie Katz Gideon Darko Asamoah Lori-Ann Linkins Wael Abdelkader Andrew Beck Alexandria Bennett Sarah E Hughes Maureen Smith Mpho Begin Doug Coyle Thomas Piggott Benjamin M Kagina Vivian Welch Caroline Colijn David J D Earn Khaled El Emam Source Type: research
An mRNA-based reverse-vaccinology strategy to stimulate the immune response against Nipah virus in humans using fusion glycoproteins
Acta Biochim Pol. 2023 Sep 17. doi: 10.18388/abp.2020_6721. Online ahead of print.ABSTRACTThe zoonotic pathogen, Nipah virus, is considered a potential healthcare threat due to its high mortality rates and detrimental symptoms like encephalitis. Ribavirin, an antiviral drug helps in overcoming the number of casualties and reducing the mortality rate, but no long-lasting solution has been proposed yet putting global health security in jeopardy. Given the cognizance of mRNA-based vaccines as safe and efficacious preventative strategies against pathogens, the current study has utilized the reverse-vaccinology approach coupled...
Source: Acta Biochim Pol - September 17, 2023 Category: Biochemistry Authors: Muhammad Naveed Sarmad Mehmood Tariq Aziz Muhammad Hammad Arif Urooj Ali Faisal Nouroz Christos Zacharis Metab Alharbi Abdulrahman Alshammari Abdullah F Alasmari Source Type: research
Erratum to "Maternal Immunization During the Second Trimester with BNT162b2 mRNA Vaccine Induces a Robust IgA Response in Human Milk: A Prospective Cohort Study" The American Journal of Clinical Nutrition volume 118 (2023) 572-578/Article Number
Am J Clin Nutr. 2023 Sep 14:S0002-9165(23)66126-X. doi: 10.1016/j.ajcnut.2023.09.002. Online ahead of print.NO ABSTRACTPMID:37717944 | DOI:10.1016/j.ajcnut.2023.09.002
Source: The American Journal of Clinical Nutrition - September 17, 2023 Category: Nutrition Authors: Aya Kigel Sharon Vanetik Laurence Mangel Gal Friedman Chen Nozik Camilla Terracina David Taussig Yael Dror Hadar Samra Dror Mandel Ronit Lubetzky Yariv Wine Source Type: research
Baseline immune states (BIS) associated with vaccine responsiveness and factors that shape the BIS
Semin Immunol. 2023 Sep 15;70:101842. doi: 10.1016/j.smim.2023.101842. Online ahead of print.ABSTRACTVaccines are among the greatest inventions in medicine, leading to the elimination or control of numerous diseases, including smallpox, polio, measles, rubella, and, most recently, COVID-19. Yet, the effectiveness of vaccines varies among individuals. In fact, while some recipients mount a robust response to vaccination that protects them from the disease, others fail to respond. Multiple clinical and epidemiological factors contribute to this heterogeneity in responsiveness. Systems immunology studies fueled by advances in...
Source: Seminars in Immunology - September 17, 2023 Category: Allergy & Immunology Authors: Djamel Nehar-Belaid Mark Sokolowski Sathyabaarathi Ravichandran Jacques Banchereau Damien Chaussabel Duygu Ucar Source Type: research
Erratum to "Maternal Immunization During the Second Trimester with BNT162b2 mRNA Vaccine Induces a Robust IgA Response in Human Milk: A Prospective Cohort Study" The American Journal of Clinical Nutrition volume 118 (2023) 572-578/Article Number
Am J Clin Nutr. 2023 Sep 14:S0002-9165(23)66126-X. doi: 10.1016/j.ajcnut.2023.09.002. Online ahead of print.NO ABSTRACTPMID:37717944 | DOI:10.1016/j.ajcnut.2023.09.002
Source: Am J Clin Nutr - September 17, 2023 Category: Nutrition Authors: Aya Kigel Sharon Vanetik Laurence Mangel Gal Friedman Chen Nozik Camilla Terracina David Taussig Yael Dror Hadar Samra Dror Mandel Ronit Lubetzky Yariv Wine Source Type: research
Quantification of camelid cytokine mRNA expression in PBMCs by microfluidic qPCR technology
Dev Comp Immunol. 2023 Sep 15:105061. doi: 10.1016/j.dci.2023.105061. Online ahead of print.ABSTRACTCamelids are economically and socially important in several parts of the world and might carry pathogens with epizootic or zoonotic potential. However, biological research in these species is limited due to lack of reagents. Here, we developed RT-qPCR assays to quantify a panel of camelid innate and adaptive immune response genes, which can be monitored in a single run. The assays were validated with PHA, PMA-ionomycin, and Poly I:C-stimulated PBMCs from alpaca, dromedary camel and llama, including normalization by multiple ...
Source: Developmental and Comparative Immunology - September 17, 2023 Category: Allergy & Immunology Authors: Jordi Rodon Nigeer Te Maria Ballester Joaquim Segal és J úlia Vergara-Alert Albert Bensaid Source Type: research
Erratum to "Maternal Immunization During the Second Trimester with BNT162b2 mRNA Vaccine Induces a Robust IgA Response in Human Milk: A Prospective Cohort Study" The American Journal of Clinical Nutrition volume 118 (2023) 572-578/Article Number
Am J Clin Nutr. 2023 Sep 14:S0002-9165(23)66126-X. doi: 10.1016/j.ajcnut.2023.09.002. Online ahead of print.NO ABSTRACTPMID:37717944 | DOI:10.1016/j.ajcnut.2023.09.002
Source: The American Journal of Clinical Nutrition - September 17, 2023 Category: Nutrition Authors: Aya Kigel Sharon Vanetik Laurence Mangel Gal Friedman Chen Nozik Camilla Terracina David Taussig Yael Dror Hadar Samra Dror Mandel Ronit Lubetzky Yariv Wine Source Type: research
Baseline immune states (BIS) associated with vaccine responsiveness and factors that shape the BIS
Semin Immunol. 2023 Sep 15;70:101842. doi: 10.1016/j.smim.2023.101842. Online ahead of print.ABSTRACTVaccines are among the greatest inventions in medicine, leading to the elimination or control of numerous diseases, including smallpox, polio, measles, rubella, and, most recently, COVID-19. Yet, the effectiveness of vaccines varies among individuals. In fact, while some recipients mount a robust response to vaccination that protects them from the disease, others fail to respond. Multiple clinical and epidemiological factors contribute to this heterogeneity in responsiveness. Systems immunology studies fueled by advances in...
Source: Seminars in Immunology - September 17, 2023 Category: Allergy & Immunology Authors: Djamel Nehar-Belaid Mark Sokolowski Sathyabaarathi Ravichandran Jacques Banchereau Damien Chaussabel Duygu Ucar Source Type: research
TWiV 1045: Less Lassa, CRISPR RNA viruses
TWiV reviews a Lassa virus mRNA vaccine that confers protection against disease without inducing neutralizing antibodies, and a CRISPR-based method for engineering the genome of RNA viruses. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Brianne Barker, and Angela Mingarelli Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Research assistant position in Rosenfeld Lab CBER/FDA (pdf) Virologist Bob Lamb dies (Northwestern Now) Lassa virus mRNA vaccine (Nat Commun) CRISPR engineering of RNA vi...
Source: This Week in Virology - MP3 Edition - September 17, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
Examining the Influence of Imbalanced Social Contact Matrices in Epidemic Models
Am J Epidemiol. 2023 Sep 15:kwad185. doi: 10.1093/aje/kwad185. Online ahead of print.ABSTRACTTransmissible infections such as those caused by SARS-CoV-2 spread according to who contacts whom. Therefore, many epidemic models incorporate contact patterns through contact matrices. Contact matrices can be generated from social contact survey data. However, the resulting matrices are often imbalanced, such that the total number of contacts reported by group A with group B do not match those reported by group B with group A. We examine the theoretical influence of imbalanced contact matrices on the estimated basic reproduction n...
Source: Am J Epidemiol - September 16, 2023 Category: Epidemiology Authors: Mackenzie Hamilton Jesse Knight Sharmistha Mishra Source Type: research
Decoding the invasive nature of a tropical pathogen of concern: The invasive non-Typhoidal Salmonella strains causing host-restricted extraintestinal infections worldwide
Microbiol Res. 2023 Sep 12;277:127488. doi: 10.1016/j.micres.2023.127488. Online ahead of print.ABSTRACTInvasive-Non-Typhoidal Salmonella (iNTS) are the major cause of health concern in the low-income, under-developed nations in Africa and Asia that lack proper sanitation facilities. Around 5% of the NTS cases give rise to invasive, extraintestinal diseases leading to focal infections like osteomyelitis, meningitis, osteoarthritis, endocarditis and neonatal sepsis. iNTS serovars like S. Typhimurium, S. Enteritidis, S. Dublin, S. Choleraesuis show a greater propensity to become invasive than others which hints at the geneti...
Source: Cell Research - September 16, 2023 Category: Cytology Authors: Dipasree Hajra Abhilash Vijay Nair Dipshikha Chakravortty Source Type: research
