Filtered By:
Cancer: Colorectal Cancer
This page shows you your search results in order of date. This is page number 10.
Order by Relevance | Date
Total 40091 results found since Jan 2013.
Modeling Tumor Growth Using Partly Conditional Survival Models: A Case Study in Colorectal Cancer
CONCLUSION: The PC modeling approach offers flexible characterization of associations between longitudinal covariates, such as serially assessed tumor burden, and survival time. It can be applied to a variety of data of this nature and used as clinical trials are ongoing to incorporate new disease assessment information as it is accumulated, as indicated by an example from colorectal cancer.PMID:37713655 | DOI:10.1200/CCI.22.00203
Source: Clinical Colorectal Cancer - September 15, 2023 Category: Cancer & Oncology Authors: Jessica R Flynn Michael Curry Binsheng Zhao Hao Yang Laurent Dercle Antonio Tito Fojo Dana E Connors Lawrence H Schwartz Mithat G önen Chaya S Moskowitz Source Type: research
Global burden of early-onset colorectal cancer among people aged 40-49 years from 1990 to 2019 and predictions to 2030
CONCLUSION: The current and future burden of EO-CRC among people aged 40-49 years is heavy. Substantial variation exists in disease burden across regions and countries. Urgent screening actions and policies are needed.PMID:37712957 | DOI:10.1007/s00432-023-05395-6
Source: Clinical Colorectal Cancer - September 15, 2023 Category: Cancer & Oncology Authors: Xiaowei Tang Jieyu Peng Shu Huang Huan Xu Ping Wang Jiao Jiang Wei Zhang Xiaomin Shi Lei Shi Xiaolin Zhong Muhan L ü Source Type: research
The microRNA-4766/VEGFA axis mediates macrophage M2-type polarization to inhibit colorectal cancer proliferation and migration
CONCLUSION: Restoring miR-4766 expression to inhibit VEGFA expression promised to be a potential strategy to suppress CRC development.PMID:37713737 | DOI:10.1016/j.prp.2023.154767
Source: Pathology, Research and Practice - September 15, 2023 Category: Pathology Authors: Chen Chen Zhiguo Huang Xinyu Tan Ruolong Wang Jia Liu Mu Zhang Source Type: research
Chronic exposure to low-dose deltamethrin can lead to colon tissue injury through PRDX1 inactivation-induced mitochondrial oxidative stress injury and gut microbial dysbiosis
CONCLUSION: Chronic exposure to DLM, even at small doses, can cause damage to the colon tissue, which cannot be ignored. The production and use of pesticides such as DLM should be strictly regulated during agricultural production.PMID:37714033 | DOI:10.1016/j.ecoenv.2023.115475
Source: Ecotoxicology and Environmental Safety - September 15, 2023 Category: Environmental Health Authors: Rulan Ma Tuanhe Sun Xueni Wang Kaijie Ren Tianhao Min Xin Xie Dangdang Wang Kang Li Yong Zhang Kun Zhu Caijing Mo Chengxue Dang Yong Yang Hao Zhang Source Type: research
Retracted Functional characterization of the nitrogen permease regulator ‑like‑2 candidate tumor suppressor gene in colorectal cancer cell lines
Mol Med Rep. 2023 Nov;28(5):201. doi: 10.3892/mmr.2023.13088. Epub 2023 Sep 15.ABSTRACTFollowing the publication of this paper, it was drawn to the Editor's attention by a concerned reader that certain of the microscopic images shown in Fig. 1C on p. 3489 and the invasion assay images shown in Fig. 5 on p. 3491 were strikingly similar to data appearing in different form in other articles written by different authors at different research institutes. Moreover, unexpected similarities were identified comparing between a pair of the flow cytometric assay data panels in Fig. 4 on p. 3490, considering that these data were inten...
Source: Molecular Medicine - September 15, 2023 Category: Molecular Biology Authors: Ai-Yun Liu Ming-Na Liu Feng-Hua Pei Jing Chen Xin-Hong Wang Dan Liu Ya-Ju Du Bing-Rong Liu Source Type: research
Extent of Lymph Node Harvest: A Retrospective Cohort Comparison of Intracorporeal Versus Extracorporeal Anastomosis in Right Hemicolectomy
Conclusions: In our experience, ICA has higher lymph node harvest in comparison to ECA. This may improve outcomes and options for adjuvant therapies in malignant indications.PMID:37713300 | DOI:10.1089/lap.2023.0246
Source: Adv Data - September 15, 2023 Category: Epidemiology Authors: Katlin Mallette Christopher M Schlachta Jeffrey Hawel Ahmad Elnahas Nawar A Alkhamesi Source Type: research
Correlation between High Incidence of Colorectal Neoplastic Polyps and High-risk Adenomas in Patients with Diabetes Mellitus: A Retrospective Study
CONCLUSION: This study demonstrated that patients with DM, age ≥ 50 years, male gender, alcohol consumption, and a first-degree relative with a history of CRC should undergo regular endoscopic screening and colonic polypectomy.PMID:37711116 | DOI:10.2174/1871530323666230913105743
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - September 15, 2023 Category: Endocrinology Authors: Chuan-Yu Zheng Wa Zhong Ji-Hao Xu Yu-Hong Yuan Nai-Zhao Chen Wei-Ling Liang Qi-Kui Chen Yu Lai Source Type: research
Activated MKK3/MYC crosstalk impairs dabrafenib response in BRAFV600E colorectal cancer leading to resistance
Biomed Pharmacother. 2023 Sep 13;167:115480. doi: 10.1016/j.biopha.2023.115480. Online ahead of print.ABSTRACTColorectal cancer (CRC) patients with BRAF mutations develop resistance to BRAF inhibitors at a very early stage. Understanding the molecular mechanisms involved in BRAF inhibitor resistance is critical for the development of novel therapeutic opportunities for this subtype of CRC patients. CRC cells bearing BRAF mutations are mostly sensitive to the abrogation of Mitogen-Activated Protein Kinase Kinase 3 (MKK3), a specific activator of p38MAPKs signaling, suggesting that BRAF alterations might addict CRC cells to ...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 15, 2023 Category: Drugs & Pharmacology Authors: Angelina Pranteda Valentina Piastra Martina Serra Roberta Bernardini Federica Lo Sardo Silvia Carpano Maria Grazia Diodoro Armando Bartolazzi Michele Milella Giovanni Blandino Gianluca Bossi Source Type: research
Natural products and mitochondrial allies in colorectal cancer therapy
Biomed Pharmacother. 2023 Sep 13;167:115473. doi: 10.1016/j.biopha.2023.115473. Online ahead of print.ABSTRACTColorectal cancer (CRC) is a globally prevalent malignancy with a high potential for metastasis. Existing cancer treatments have limitations, including drug resistance and adverse effects. Researchers are striving to develop effective therapies to address these challenges. Impressively, contemporary research has discovered that many natural products derived from foods, plants, insects, and marine invertebrates can suppress the progression, metastasis, and invasion of CRC. In this review, we conducted a comprehensiv...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 15, 2023 Category: Drugs & Pharmacology Authors: Feng Wei Qing Nian Maoyuan Zhao Yueqiang Wen Yi Yang Jundong Wang Zhelin He Xiaoyan Chen Xiang Yin Jian Wang Xiao Ma Yu Chen Peimin Feng Jinhao Zeng Source Type: research
Effects of obesity, and of weight loss following bariatric surgery, on methylation of DNA from the rectal mucosa and in cell-free DNA from blood
CONCLUSION: BS reversed LINE1, POMC and LEP methylation in the rectal mucosa of patients with obesity to levels similar to those in individuals without obesity. These findings support current evidence of effects of BS-induced weight loss on reversibility of DNA methylation in other tissues. The DNA methylation changes in the rectal mucosa shows promise as a biomarker for objective assessment of effects of weight loss interventions on risk of cancer and other diseases.PMID:37714902 | DOI:10.1038/s41366-023-01384-4
Source: Cancer Control - September 15, 2023 Category: Cancer & Oncology Authors: Khalil ElGendy Fiona C Malcomson Sorena Afshar Michael D Bradburn John C Mathers Source Type: research
Effect of perioperative airway management on postoperative outcomes of colorectal cancer patients with sarcopenia
CONCLUSION: The perioperative airway management program implemented at our center was easy to perform and can effectively improve short-term postoperative outcomes in colorectal cancer patients with sarcopenia.PMID:37713967 | DOI:10.1016/j.ejon.2023.102418
Source: European Journal of Oncology Nursing - September 15, 2023 Category: Nursing Authors: Tingting Xie Liyuan Li Xiangxiang Yang Xiaofen Wu Minmin Wang Weizhe Chen Qiantong Dong Xiaolei Chen Jiang Li Source Type: research
Manganese-based nanoparticles for chemodynamic therapy of gastrointestinal cancer
CONCLUSION: MSN@Mn-GOx nanoparticles have good chemodynamic properties and a strong anti-tumor effect and provide a potential therapeutic option for gastric cancer.PMID:37712282 | DOI:10.12122/j.issn.1673-4254.2023.08.22
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: X Lin M Huang J Chen X Zhou Z Zhong W Lu X Huang T Liu Source Type: research
Metformin inhibits self-renewal of colorectal cancer stem cells by inhibiting mitochondrial oxidative phosphorylation
CONCLUSION: Metformin reduces mitochondrial oxidative phosphorylation and ROS levels by inhibiting mitochondrial complex Ⅰ, thereby suppressing Wnt signaling pathway to reduce selfrenewal ability of colorectal CSCs.PMID:37712263 | DOI:10.12122/j.issn.1673-4254.2023.08.03
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: C Yan S Liu Q Song Y Hu Source Type: research
The microRNA-4766/VEGFA axis mediates macrophage M2-type polarization to inhibit colorectal cancer proliferation and migration
CONCLUSION: Restoring miR-4766 expression to inhibit VEGFA expression promised to be a potential strategy to suppress CRC development.PMID:37713737 | DOI:10.1016/j.prp.2023.154767
Source: Cell Research - September 15, 2023 Category: Cytology Authors: Chen Chen Zhiguo Huang Xinyu Tan Ruolong Wang Jia Liu Mu Zhang Source Type: research
