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Utility of psychotherapy assessed with Kessler scale in a population of cancer patients undergoing systemic oncological treatment: a mono-institutional experience
CONCLUSIONS: The use of the K10 test is helpful in monitoring the degree of psychological distress of patients facing the diagnosis of cancer and who are about to start oncological treatment. Psychotherapy is effective in reducing the distress of these patients just a few months after starting treatment.PMID:37699600 | DOI:10.21037/cco-23-54
Source: Clinical Breast Cancer - September 12, 2023 Category: Cancer & Oncology Authors: Pasquale Vitale Ida Bocchino Vincenzo De Falco Gelsomina Auletta Ilaria Di Giovanni Marco Bocchetti Annunziata Auriemma Roberto Conchiglia Raffaele Addeo Source Type: research

The Influence of the Preoperative Albumin to Alkaline Phosphatase Ratio on Overall Survival in Post-Radical Surgery for Colorectal Cancer and the Construction of a Nomogram Prediction Model
CONCLUSIONS: Preoperative AAPR level was a good predictor of postoperative survival in patients undergoing laparoscopic radical CRC surgery, and AAPR <.495 was an independent risk factor for decreased postoperative OS.PMID:37698898 | DOI:10.1177/00031348231200674
Source: The American Surgeon - September 12, 2023 Category: Surgery Authors: Wenliang Jiang Feng Xun Zhenchi Li Yong Xia Haoran Hu Yujun Liu Zhibin Zhao Honggang Wang Source Type: research

Survival outcome in early onset metastatic colorectal cancer: a multicenter matched-pair analysis
Conclusion Our study suggests that younger patients benefit at least to the same magnitude or even more from mCRC-treatment than patients aged 50 or above.PMID:37699362 | DOI:10.1159/000533429
Source: Cancer Control - September 12, 2023 Category: Cancer & Oncology Authors: Bernhard Doleschal Dora Nieders üß-Beke Patrick Kirchweger Andreas Petzer Josef Thaler Holger Rumpold Source Type: research

Lymph Node Metastases and Associated Recurrence-Free Survival in Microsatellite Stable and Unstable Colon Cancer
CONCLUSIONS: In MSI colon cancer, LNMs are 50 % less prevalent, but the factors associated with LNM are like those in MSS colon cancer. The improved prognosis traditionally associated with early-stage MSI colon cancers dissipates with four or more LNMs. These findings should be taken into consideration by clinicians selecting the most appropriate course of treatment for MSI colon cancer.PMID:37700171 | DOI:10.1245/s10434-023-14270-0
Source: Ann Oncol - September 12, 2023 Category: Cancer & Oncology Authors: Lynn Hakki Asama Khan Mithat Gonen Zsofia Stadler Neil H Segal Jinru Shia Maria Widmar Iris H Wei J Joshua Smith Emmanouil P Pappou Garrett M Nash Philip B Paty Julio Garcia-Aguilar Martin R Weiser Source Type: research

The predictive value of advanced lung cancer inflammation index for short-term outcomes and prognosis of colorectal cancer patients who underwent radical surgery
CONCLUSION: Lower ALI was associated with more postoperative complications, worse OS, and DFS for CRC patients who underwent radical surgery. Furthermore, ALI was an independent risk factor for overall complications, OS, and DFS. Surgeons should pay close attention to patients with low ALI before surgery and make clinical strategies cautiously.PMID:37700210 | DOI:10.1007/s10147-023-02410-1
Source: Clinical Lung Cancer - September 12, 2023 Category: Cancer & Oncology Authors: Bin Zhang Zi-Wei Li Yue Tong Chao Yuan Xiao-Yu Liu Zheng-Qiang Wei Wei Zhang Dong Peng Source Type: research

Utility of psychotherapy assessed with Kessler scale in a population of cancer patients undergoing systemic oncological treatment: a mono-institutional experience
CONCLUSIONS: The use of the K10 test is helpful in monitoring the degree of psychological distress of patients facing the diagnosis of cancer and who are about to start oncological treatment. Psychotherapy is effective in reducing the distress of these patients just a few months after starting treatment.PMID:37699600 | DOI:10.21037/cco-23-54
Source: Clinical Lung Cancer - September 12, 2023 Category: Cancer & Oncology Authors: Pasquale Vitale Ida Bocchino Vincenzo De Falco Gelsomina Auletta Ilaria Di Giovanni Marco Bocchetti Annunziata Auriemma Roberto Conchiglia Raffaele Addeo Source Type: research

Predictive and Prognostic Role of Neutrophil to Lymphocyte Ratio in Rectal Cancer: A Case Control Study with Propensity Score Analysis
Conclusions: Overall, a pretherapeutic high NLR ( 2.58) was not found to predict survival or response do neoadjuvant therapy in patients with rectal cancer. However, a higher NLR may be associated with worse outcomes in advanced colorectal cancer.PMID:37698002 | DOI:10.21614/chirurgia.2023.v.118.i.4.p.399
Source: Cancer Control - September 12, 2023 Category: Cancer & Oncology Authors: Constantin Simiras Stefan Morarasu Delia-Maria Simiras Stefan Iacob Wee Liam Ong Ana Maria Musina Natalia Velenciuc Cristian Ene Roata Sorinel Lunca Gabriel-Mihail Dimofte Source Type: research

GRECCAR 14 - a multicentric, randomized, phase II-III study evaluating the tailored management of locally advanced rectal carcinoma after a favourable response to induction chemotherapy: study protocol
CONCLUSION: If GRECCAR 14 demonstrates the ability to tailor TNT for LARC, this could lead to changes in clinical practice.PMID:37697712 | DOI:10.1111/codi.16740
Source: Cancer Control - September 12, 2023 Category: Cancer & Oncology Authors: Philippe Rouanet Florence Castan Thibault Mazard Claire Lemanski Stephanie Nougaret Emmanuel Deshayes Patrick Chalbos Sophie Gourgou Christophe Taoum GRECCAR, PRODIGE study group Source Type: research

A novel cuproptosis-related gene prognostic signature in colon adenocarcinoma
This study plans to establish a survival prognosis model for colon adenocarcinoma (COAD) patients based on cuproptosis-related genes (CRGs). We investigated the genetic alterations of CRGs in COAD based on The Cancer Genome Atlas database and validated in the GSE41328 dataset. Our results showed that LIPT1, PDHA1, GLS, and CDKN2A had significantly higher expression in COAD tissues than in normal tissues, while FDX1, DLD, and MTF1 had significantly lower expression in COAD tissues than in normal tissues (|(log2(fold change))| > 2, p < 0.05). DLD (hazard ratio (HR): 0.658; 95% confidence interval (CI): 0.445, 0.974; p ...
Source: Canadian Journal of Physiology and Pharmacology - September 12, 2023 Category: Drugs & Pharmacology Authors: Yongqin Su Kun Zhang Source Type: research

Are 7.5gy ×2 fractions more efficient than 6gy×3 in exclusive postoperative endometrial cancer brachytherapy? a clinical and dosimetrical analysis
CONCLUSION: Considering the lack of vaginal relapses and similar LVT over time, 7.5Gy×2fractions seem more efficient in terms of patient comfort, workload, and cost. This is the first study using dosimetry parameters to compare effectivity of schedules. Larger series are needed to confirm the present results.PMID:37699447 | DOI:10.1016/j.radonc.2023.109909
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - September 12, 2023 Category: Radiology Authors: Faegheh Noorian Rosa Abellana Yaowen Zhang Antonio Herreros Clara Baltrons Vallentina Lancellota Luca Tagliaferri Sebastia Sabater Aureli Torne Angeles Rovirosa Source Type: research

Predicting Trifluridine/Tipiracil Treatment Outcomes in Refractory Metastatic Colorectal Cancer Patients: A Multicenter Exploratory Analysis
CONCLUSION: With regard to the results of the previously conducted trials, the study concludes that indolent disease, good general condition, and absence of liver metastases are positive predictive factors for TTP treatment.PMID:37699377 | DOI:10.1159/000533567
Source: Oncology - September 12, 2023 Category: Cancer & Oncology Authors: Juraj Prejac Tomislav Omr čen Jasna Radi ć Eduard Vrdoljak Ana Fr öbe Stjepko Ple ština Source Type: research

Impact of oophorectomy on survival and improving nutritional status in ovarian metastasis from colorectal adenocarcinoma
CONCLUSIONS: Oophorectomy for ovarian metastasis from colorectal cancers was safely performed. It improved the patients' symptoms and nutritional status and may result in improved prognosis.PMID:37699374 | DOI:10.1159/000533599
Source: Oncology - September 12, 2023 Category: Cancer & Oncology Authors: Yusuke Miyagawa Masato Kitazawa Shigeo Tokumaru Satoshi Nakamura Makoto Koyama Yuta Yamamoto Satoru Miyazaki Nao Hondo Yuji Soejima Source Type: research

Survival outcome in early onset metastatic colorectal cancer: a multicenter matched-pair analysis
Conclusion Our study suggests that younger patients benefit at least to the same magnitude or even more from mCRC-treatment than patients aged 50 or above.PMID:37699362 | DOI:10.1159/000533429
Source: Oncology - September 12, 2023 Category: Cancer & Oncology Authors: Bernhard Doleschal Dora Nieders üß-Beke Patrick Kirchweger Andreas Petzer Josef Thaler Holger Rumpold Source Type: research

The predictive value of advanced lung cancer inflammation index for short-term outcomes and prognosis of colorectal cancer patients who underwent radical surgery
CONCLUSION: Lower ALI was associated with more postoperative complications, worse OS, and DFS for CRC patients who underwent radical surgery. Furthermore, ALI was an independent risk factor for overall complications, OS, and DFS. Surgeons should pay close attention to patients with low ALI before surgery and make clinical strategies cautiously.PMID:37700210 | DOI:10.1007/s10147-023-02410-1
Source: Clinical Colorectal Cancer - September 12, 2023 Category: Cancer & Oncology Authors: Bin Zhang Zi-Wei Li Yue Tong Chao Yuan Xiao-Yu Liu Zheng-Qiang Wei Wei Zhang Dong Peng Source Type: research

Erratum: FOLFOXIRI Plus Cetuximab or Bevacizumab as First-Line Treatment of BRAFV600E-Mutant Metastatic Colorectal Cancer: The Randomized Phase II FIRE-4.5 (AIO KRK0116) Study
J Clin Oncol. 2023 Sep 12:JCO2301858. doi: 10.1200/JCO.23.01858. Online ahead of print.NO ABSTRACTPMID:37699171 | DOI:10.1200/JCO.23.01858
Source: Clinical Colorectal Cancer - September 12, 2023 Category: Cancer & Oncology Source Type: research