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Total 80126 results found since Jan 2013.

The effects of sensorimotor and linguistic information on the basic-level advantage
Cognition. 2023 Sep 16;241:105606. doi: 10.1016/j.cognition.2023.105606. Online ahead of print.ABSTRACTThe basic-level advantage is one of the best-known effects in human categorisation. Traditional accounts argue that basic-level categories present a maximally informative or entry level into a taxonomic organisation of concepts in semantic memory. However, these explanations are not fully compatible with most recent views on the structure of the conceptual system such as linguistic-simulation accounts, which emphasise the dual role of sensorimotor (i.e., perception-action experience of the world) and linguistic distributi...
Source: Cognition - September 18, 2023 Category: Neurology Authors: Rens van Hoef Louise Connell Dermot Lynott Source Type: research

Persian version of the Chalder Fatigue Questionnaire and Multidimensional Fatigue Symptom Inventory-Short Form: psychometric properties in Iranian chronic stroke survivors
CONCLUSIONS: The results of this study showed that the CFQ and MFSI-SF have high reliability and validity for chronic stroke survivors.PMID:37723098 | DOI:10.1080/10749357.2023.2175421
Source: Topics in Stroke Rehabilitation - September 18, 2023 Category: Neurology Authors: Soheila Fallah Ghorban Taghizadeh Zahra Parnain Moslem Cheraghifard Parvaneh Taghavi Azar Sharabiani Mahin Yousefi Mohammad Taghi Joghataei Ali Gholizade Source Type: research

Impact of rehabilitation adherence and depressive symptoms on post-stroke self-care ability and quality of life: a longitudinal study
CONCLUSION: Both depressive symptoms and rehabilitation adherence behavior impacted the rehabilitation effect among patients who are recovering from a stroke.PMID:37722691 | DOI:10.1080/10749357.2023.2259652
Source: Topics in Stroke Rehabilitation - September 18, 2023 Category: Neurology Authors: Jeng Wang Wen-Yu Kuo Min-Chi Chen Chen-Yin Chen Source Type: research

The effects of sensorimotor and linguistic information on the basic-level advantage
Cognition. 2023 Sep 16;241:105606. doi: 10.1016/j.cognition.2023.105606. Online ahead of print.ABSTRACTThe basic-level advantage is one of the best-known effects in human categorisation. Traditional accounts argue that basic-level categories present a maximally informative or entry level into a taxonomic organisation of concepts in semantic memory. However, these explanations are not fully compatible with most recent views on the structure of the conceptual system such as linguistic-simulation accounts, which emphasise the dual role of sensorimotor (i.e., perception-action experience of the world) and linguistic distributi...
Source: Cognition - September 18, 2023 Category: Neurology Authors: Rens van Hoef Louise Connell Dermot Lynott Source Type: research

Secondary surgical procedures following motor nerve injuries
CONCLUSIONS: Secondary surgical procedures are a valuable option for functional reconstruction after nerve injury.PMID:37721574 | DOI:10.1007/s00115-023-01543-y
Source: Der Nervenarzt - September 18, 2023 Category: Neurology Authors: Johannes Heinzel Cosima Prahm Henrik Lauer Adrien Daigeler Helene Hurth Martin Schuhmann Jonas Kolbenschlag Source Type: research

Corrigendum to "Understanding the role of the hematopoietic niche in Huntington's disease's phenotypic expression: In vivo evidence using a parabiosis model" Neurobiol Dis. 2023 May;180:106091. doi:10.1016/j.nbd.2023.106091. Epub 2023 Mar 24
Neurobiol Dis. 2023 Sep 16:106289. doi: 10.1016/j.nbd.2023.106289. Online ahead of print.NO ABSTRACTPMID:37722998 | DOI:10.1016/j.nbd.2023.106289
Source: Neurobiology of Disease - September 18, 2023 Category: Neurology Authors: Marie Rieux Melanie Alpaugh Shireen Salem Alberto Siddu Martine Saint-Pierre H élèna L Denis Heike Rohweder Frank Herrmann Chantal Bazenet Steve Lacroix Francesca Cicchetti Source Type: research

Secondary surgical procedures following motor nerve injuries
CONCLUSIONS: Secondary surgical procedures are a valuable option for functional reconstruction after nerve injury.PMID:37721574 | DOI:10.1007/s00115-023-01543-y
Source: Der Nervenarzt - September 18, 2023 Category: Neurology Authors: Johannes Heinzel Cosima Prahm Henrik Lauer Adrien Daigeler Helene Hurth Martin Schuhmann Jonas Kolbenschlag Source Type: research

Resveratrol ameliorates diabetic encephalopathy through PDE4D/PKA/Drp1 signaling
This study illustrated the role of PDE4D in DE and investigated whether resveratrol protected against DE via inhibiting PDE4D. db/db male mice and hippocampus cell line (HT22) were used to investigate the role of PDE4D and the protective effect of resveratrol on cognitive function under high glucose (HG). PDE4D overexpression or knockdown lentivirus and PKA specific inhibitor H89 were used to further identify the indispensable role of PDE4D/PKA signaling pathway in resveratrol's amelioration effect of neurotoxicity. Resveratrol attenuated cognitive impairment in db/db mice, reduced PDE4D protein, restored the impaired mito...
Source: Brain Research - September 18, 2023 Category: Neurology Authors: Yanjuan Cao Wen Sun Chang Liu Zihui Zhou Zongli Deng Mingjie Zhang Meng Yan Xiaoxing Yin Xia Zhu Source Type: research

Comparison of three DREADD agonists acting on Gq-DREADDs in the ventral tegmental area to alter locomotor activity in tyrosine hydroxylase:Cre male and female rats
CONCLUSIONS: Large individual variability was observed in both DREADD agonist behavioral effects and receptor expression. These results suggest further basic research would facilitate the utility of these chemogenetic tools for behavioral neuroscience research.PMID:37722510 | DOI:10.1016/j.bbr.2023.114674
Source: Brain Research - September 18, 2023 Category: Neurology Authors: Hannah L Robinson Katherine L Nicholson Keith L Shelton Peter J Hamilton Matthew L Banks Source Type: research

Protective effect of cornuside on OGD/R injury in SH-SY5Y cells and its underlying mechanism
In this study, we treated SH-SY5Y cells with OGD/R to simulated ischemia/reperfusion (I/R) injury. Using high-throughput transcriptome sequencing, differentially expressed genes were analyzed in the OGD/R group versus the OGD/R + Cornuside (10 μmol/L) group to explore the neuroprotective mechanisms of Cornuside. The differentially expressed genes were mainly enriched in apoptosis signaling pathway, cell cycle, DNA damage and repair, and p38/JNK MAPK and p53 signaling pathways. The results showed that OGD/R significantly reduced the survival of SH-SY5Y cells, induced apoptosis, disrupted the nucleus, promoted the release o...
Source: Brain Research - September 18, 2023 Category: Neurology Authors: Xinyu Wang Chao Yan Chaoyun Wang Xiaoyan Xu Zhihao Liu Wang Xin Jianwei Gong Source Type: research

Clinical and surgical outcome of endoscopic third ventriculostomy (ETV) and ventriculoperitoneal shunt (VPS) in patients with Long-Standing Overt Ventriculomegaly in Adults (LOVA): a systematic review
DISCUSSION: This meta-analysis confirmed the efficacy of EVT and VPS in symptomatic patients with LOVA, reporting a roughly 84% of postoperative clinical improvement or halt of progression of symptoms. A higher rate of surgical complications was observed in patients treated with VPS compared with patients treated with ETV. In addition, roughly 18% of patients treated with ETV required a further VPS. These findings should be considered when advising LOVA patients regarding the management of hydrocephalus.PMID:37722694 | DOI:10.1080/01616412.2023.2257461
Source: Neurological Research - September 18, 2023 Category: Neurology Authors: Nicola Montemurro Source Type: research

Subjective cognitive decline exhibits alterations of resting-state phase-amplitude coupling in precuneus
CONCLUSIONS: The SCD group demonstrated reduced theta-gamma PAC in the precuneus.SIGNIFICANCE: Subjective perception of cognitive decline is reflected by objective alterations of brain function.PMID:37722986 | DOI:10.1016/j.clinph.2023.08.015
Source: Clinical Neurophysiology - September 18, 2023 Category: Neurology Authors: Chia-Hsiung Cheng Chun-Che Hung Yi-Ping Chao Rui Nouchi Pei-Ning Wang Source Type: research

Comparison of three DREADD agonists acting on Gq-DREADDs in the ventral tegmental area to alter locomotor activity in tyrosine hydroxylase:Cre male and female rats
CONCLUSIONS: Large individual variability was observed in both DREADD agonist behavioral effects and receptor expression. These results suggest further basic research would facilitate the utility of these chemogenetic tools for behavioral neuroscience research.PMID:37722510 | DOI:10.1016/j.bbr.2023.114674
Source: Behavioural Brain Research - September 18, 2023 Category: Neurology Authors: Hannah L Robinson Katherine L Nicholson Keith L Shelton Peter J Hamilton Matthew L Banks Source Type: research

Mitophagy-dependent mitochondrial ROS mediates 2,5-hexanedione-induced NLRP3 inflammasome activation in BV2 microglia
In conclusion, our data indicated that HD triggered activation of NLRP3 inflammasome through mitophagy-dependent mtROS production, offering an important insight for the immunopathogenesis of environmental toxins-induced neuroinflammation and neurotoxicity.PMID:37722613 | DOI:10.1016/j.neuro.2023.09.008
Source: Neurotoxicology - September 18, 2023 Category: Neurology Authors: Wenqiong Wang Rui Chang Yan Wang Liyan Hou Qingshan Wang Source Type: research

Resveratrol ameliorates diabetic encephalopathy through PDE4D/PKA/Drp1 signaling
This study illustrated the role of PDE4D in DE and investigated whether resveratrol protected against DE via inhibiting PDE4D. db/db male mice and hippocampus cell line (HT22) were used to investigate the role of PDE4D and the protective effect of resveratrol on cognitive function under high glucose (HG). PDE4D overexpression or knockdown lentivirus and PKA specific inhibitor H89 were used to further identify the indispensable role of PDE4D/PKA signaling pathway in resveratrol's amelioration effect of neurotoxicity. Resveratrol attenuated cognitive impairment in db/db mice, reduced PDE4D protein, restored the impaired mito...
Source: Brain Research Bulletin - September 18, 2023 Category: Neurology Authors: Yanjuan Cao Wen Sun Chang Liu Zihui Zhou Zongli Deng Mingjie Zhang Meng Yan Xiaoxing Yin Xia Zhu Source Type: research