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Total 80126 results found since Jan 2013.
Referral odyssey plot to visualize causes of surgical delay in mesial temporal lobe epilepsy with hippocampal sclerosis
Epilepsy Behav. 2023 Sep 14;147:109434. doi: 10.1016/j.yebeh.2023.109434. Online ahead of print.ABSTRACTThe "odyssey plot" was used to visualize referral delays in epilepsy surgery. Participants were 36 patients (19 males; 13-67 years, median 27 years) with mesial temporal lobe epilepsy with hippocampal sclerosis (HS) who underwent resection surgery. The "referral odyssey plot" included five clinical episodes: seizure onset (T1), first visits to a non-epileptologist (T2) and to an epileptologist (T3), first admission to our epilepsy monitoring unit (EMU) (T4), and resection surgery (T5). For each patient, we identified the...
Source: Epilepsy and Behaviour - September 16, 2023 Category: Neurology Authors: Kazutoshi Konomatsu Yosuke Kakisaka Makoto Ishida Temma Soga Kazushi Ukishiro Shin-Ichiro Osawa Kazutaka Jin Masashi Aoki Nobukazu Nakasato Source Type: research
Risk of suicide and religious or spiritual beliefs in Brazilian adult patients with epilepsy
DISCUSSION: A high number of patients with epilepsy exhibited suicide risk, with epilepsy-related variables, the presence of anxiety, and perceived lower belongingness and social support from religiosity or spirituality anxiety being associated with a higher risk. The social support provided by religiosity/spirituality may be a non-clinical factor associated with suicidal behavior. Suicide in epilepsy is associated with a complex interaction of multidimensional factors.PMID:37716329 | DOI:10.1016/j.yebeh.2023.109414
Source: Epilepsy and Behaviour - September 16, 2023 Category: Neurology Authors: Yasmin Meneguci Petrarca Gl ória M A S Tedrus Source Type: research
Hypothalamic hamartoma surgery in a setting with limited resources
CONCLUSION: Hypothalamic hamartoma surgery is feasible even in centers with limited resources if a close collaboration exists between the epileptology and neurosurgery teams. Careful planning based on the expertise of the team members and the available resources is required to foster success.PMID:37716328 | DOI:10.1016/j.yebeh.2023.109439
Source: Epilepsy and Behaviour - September 16, 2023 Category: Neurology Authors: Ali A Asadi-Pooya Mohamad S Masoudi Bita Hashemi Seyedarad Mosalamiaghili Masoume Nazeri Khatereh Fazelian Source Type: research
Reliability and validation of the Chinese version of the epilepsy surgery satisfaction questionnaire
CONCLUSIONS: The C-ESSQ-19 has proven to be a reliable and valid self-rated questionnaire for assessing the satisfaction of Chinese mainland epilepsy patients with surgery.PMID:37716327 | DOI:10.1016/j.yebeh.2023.109438
Source: Epilepsy and Behaviour - September 16, 2023 Category: Neurology Authors: Qun Yu Yu-Qi Ying Si-Xuan Jiang Zheng-Yan-Ran Xu Mei-Juan Lan Yi Guo Source Type: research
Co-production of online educational resources for adolescent and young adult females with epilepsy
CONCLUSION: Our team utilized co-production with a diverse group of partners to create educational materials that met the interests of adolescent and young adult females with epilepsy. This is a structured and reproducible methodology that could inform future educational intervention development in epilepsy.PMID:37716326 | DOI:10.1016/j.yebeh.2023.109420
Source: Epilepsy and Behaviour - September 16, 2023 Category: Neurology Authors: Medha Parulekar Traci M Kazmerski Danielle Gordon Tahniat Syed Janet F R Waters Anne C Van Cott Laura Kirkpatrick Source Type: research
Seizure-related stress and arousal responses mediate a relationship between anxiety trait and state in epilepsy
CONCLUSIONS: These findings elucidate the epilepsy-specific stress and arousal characteristics and their roles in mediating traits and state anxiety. These results may reflect the long-term clinical course and unique emotion recognition tendencies in epilepsy.PMID:37716325 | DOI:10.1016/j.yebeh.2023.109442
Source: Epilepsy and Behaviour - September 16, 2023 Category: Neurology Authors: Hironobu Nakamura Genichi Sugihara Keiko Hara Motoki Inaji Masahiro Noha Ichiro Takumi Masako Watanabe Hidehiko Takahashi Taketoshi Maehara Hitoshi Yamamoto Shunsuke Takagi Source Type: research
Prevalence and predictors of vitamin D deficiency among adults with epilepsy: A cross-sectional study
CONCLUSION: Vitamin D deficiency among PWE is prevalent in our local population, suggesting that regular screening should be considered for those at risk. Early identification would allow intervention to reduce the risk of future complications.PMID:37716324 | DOI:10.1016/j.yebeh.2023.109432
Source: Epilepsy and Behaviour - September 16, 2023 Category: Neurology Authors: Ching Soong Khoo Mohd Fadzli Shukor Juen Kiem Tan Michelle Maryanne Tan Li Ling Yong Siti Zaleha Sahibulddin Siti Hajar Mat Desa Norasyikin A Wahab Rozita Hod Hui Jan Tan Source Type: research
Sevoflurane-induced hypotension causes cognitive dysfunction and hippocampal inflammation in mice
Behav Brain Res. 2023 Sep 14:114672. doi: 10.1016/j.bbr.2023.114672. Online ahead of print.ABSTRACTSevoflurane commonly adopted for anesthetic in clinical practice, however, its influences on cerebral blood flow and cognitive function remain controversial. Herein, the sevoflurane-induced hypotension on arterial blood pressure, cerebral blood flow, cognitive function, and hippocampal inflammation was investigated in mice. A significant decrease in arterial blood pressure and cerebral blood flow was indicated by the sevoflurane anesthesia treatment. Moreover, sevoflurane-induced hypotension was associated with the impaired c...
Source: Behavioural Brain Research - September 16, 2023 Category: Neurology Authors: Yuelian Luo Jiayi Liu Yu Hong Shuling Peng Shiyu Meng Source Type: research
Effect of auditory deprivation on adaptive locomotion: Interaction with lower visual field occlusion
This study aimed to investigate whether auditory deprivation affects adaptive locomotion. In particular, we aimed to elucidate the role of the auditory sense in obstacle avoidance by manipulating the visual field, which provides crucial sensory information for movement control. Sixteen participants approached a 15-cm obstacle located 6m away and stepped over it under four different conditions that combined two factors: the hearing condition controlled by wearing earmuffs with and without holes, and the lower visual field condition controlled by carrying opaque white and transparent boards. Spatiotemporal variables during t...
Source: Behavioural Brain Research - September 16, 2023 Category: Neurology Authors: Ryota Sakurai Yuka Miura Kentaro Kodama Masahiro Fujimoto Source Type: research
Nonlinear Neural Patterns Are Revealed In High Frequency Functional Near Infrared Spectroscopy Analysis
Brain Res Bull. 2023 Sep 14:110759. doi: 10.1016/j.brainresbull.2023.110759. Online ahead of print.ABSTRACTFunctional Near Infrared Spectroscopy (fNIRS) is a useful tool for measuring hemoglobin concentration. Linear theory of the hemodynamic response function supports low frequency analysis ( < 0.2 Hz). However, we hypothesized that nonlinearities, arising from the complex neurovascular interactions sustaining vasomotor tone, may be revealed in higher frequency components of fNIRS signals. To test this hypothesis, we simulated nonlinear hemodynamic models to explore how blood flow autoregulation changes may alter evoke...
Source: Brain Research Bulletin - September 16, 2023 Category: Neurology Authors: Ameer Ghouse Diego Candia Rivera Gaetano Valenza Source Type: research
Elevated CRP and TNF- α levels are associated with blunted neural oscillations serving fluid intelligence
DISCUSSION: Elevated inflammatory markers such as CRP and TNF-α were associated with aberrant neural oscillations in regions important for Gf. Linking inflammatory markers with regional neural oscillations may hold promise in identifying mechanisms of cognitive and psychiatric disorders.PMID:37716379 | DOI:10.1016/j.bbi.2023.09.012
Source: Brain, Behavior, and Immunity - September 16, 2023 Category: Neurology Authors: Sarah M Dietz Mikki Schantell Rachel K Spooner Megan E Sandal Amirsalar Mansouri Yasra Arif Hannah J Okelberry Jason A John Ryan Glesinger Pamela E May Elizabeth Heinrichs-Graham Adam J Case Matthew C Zimmerman Tony W Wilson Source Type: research
P2X < sub > 7 < /sub > R influences tau aggregate burden in human tauopathies and shows distinct signalling in microglia and astrocytes
Brain Behav Immun. 2023 Sep 14:S0889-1591(23)00275-1. doi: 10.1016/j.bbi.2023.09.011. Online ahead of print.ABSTRACTThe purinoceptor P2X7R is a promising therapeutic target for tauopathies, including Alzheimer's disease (AD). Pharmacological inhibition or genetic knockdown of P2X7R ameliorates cognitive deficits and reduces pathological tau burden in mice that model aspects of tauopathy, including mice expressing mutant human frontotemporal dementia (FTD)-causing forms of tau. However, disagreements remain over which glial cell types express P2X7R and therefore the mechanism of action is unresolved. Here, we show that P2X7...
Source: Brain, Behavior, and Immunity - September 16, 2023 Category: Neurology Authors: Paula Beltran-Lobo Martina M Hughes Claire Troakes Cara L Croft Huzefa Rupawala Daniel Jutzi Marc-David Ruepp Maria Jimenez-Sanchez Michael S Perkinton Michael Kassiou Todd E Golde Diane P Hanger Alexei Verkhratsky Beatriz G Perez-Nievas Wendy Noble Source Type: research
Omega-3 polyunsaturated fatty acids and the psychiatric post-acute sequelae of COVID-19: A one-year retrospective cohort analysis of 33,908 patients
CONCLUSION: Omega-3 PUFAs may require re-evaluation as a preventive strategy against adverse mental health outcomes post-COVID-19 in placebo-controlled clinical trials.PMID:37716377 | DOI:10.1016/j.bbi.2023.09.008
Source: Brain, Behavior, and Immunity - September 16, 2023 Category: Neurology Authors: Ting-Hui Liu Chung-Han Ho Daniel Tzu-Li Chen Jheng-Yan Wu Po-Yu Huang Chih-Cheng Lai Kuang-Yang Hsieh Kuan-Pin Su Source Type: research
CircNCOA4 knockdown attenuates OGD-induced neuron injury through miR-338-5p/PDE4B axis
Exp Brain Res. 2023 Sep 16. doi: 10.1007/s00221-023-06702-w. Online ahead of print.ABSTRACTCircular RNAs (circRNAs) have been revealed to be involved in the pathology of acute ischemic stroke (AIS). Herein, we aimed to study the role and mechanism of circNCOA4 in ischemic stroke. The neuron-like cell line SK-N-SH of the experiment group was cultured in oxygen-glucose deprivation (OGD) condition. Cell viability and apoptosis were evaluated by cell counting kit-8 and flow cytometry. The oxidative damage and endoplasmic reticulum stress (ERS) were analyzed by measuring the production of reactive oxygen species (ROS), malondia...
Source: Brain Research - September 16, 2023 Category: Neurology Authors: Danyang Wang Sai Xiao Xiaoming Li Wenbo Qi Source Type: research
Sevoflurane-induced hypotension causes cognitive dysfunction and hippocampal inflammation in mice
Behav Brain Res. 2023 Sep 14:114672. doi: 10.1016/j.bbr.2023.114672. Online ahead of print.ABSTRACTSevoflurane commonly adopted for anesthetic in clinical practice, however, its influences on cerebral blood flow and cognitive function remain controversial. Herein, the sevoflurane-induced hypotension on arterial blood pressure, cerebral blood flow, cognitive function, and hippocampal inflammation was investigated in mice. A significant decrease in arterial blood pressure and cerebral blood flow was indicated by the sevoflurane anesthesia treatment. Moreover, sevoflurane-induced hypotension was associated with the impaired c...
Source: Brain Research - September 16, 2023 Category: Neurology Authors: Yuelian Luo Jiayi Liu Yu Hong Shuling Peng Shiyu Meng Source Type: research
