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Nutrition: Antidoxidants
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Total 54860 results found since Jan 2013.
Feasibility and acceptability of miracle fruit application prior to the consumption of sour-tasting foods as a weight-loss strategy in adults with diabetes or prediabetes: A randomized crossover trial
Appetite. 2023 Sep 17:107046. doi: 10.1016/j.appet.2023.107046. Online ahead of print.ABSTRACTMiracle fruit (MF) has emerged as a promising option for healthy noncaloric sweeteners due to its sour-to-sweet taste-modifying effects and high antioxidant activity. We aimed to examine the feasibility and acceptability of using MF as a weight-loss strategy for individuals with diabetes or prediabetes. Fifty Korean-American men and women (25 participants each) aged 45-75 years with diabetes or prediabetes were recruited in this study. They participated in a randomized placebo-controlled crossover trial where they took the assigne...
Source: Appetite - September 19, 2023 Category: Nutrition Authors: Sung Eun Choi Taehwan Park Source Type: research
Physiological and metabolomic analyses reveal that Fe < sub > 3 < /sub > O < sub > 4 < /sub > nanoparticles ameliorate cadmium and arsenic toxicity in Panax notoginseng
This study provides insights into using nanoparticles to improve potential active ingredients of medicinal plants in metal (loid)-contaminated areas.PMID:37726032 | DOI:10.1016/j.envpol.2023.122578
Source: Environmental Pollution - September 19, 2023 Category: Environmental Health Authors: Tianquan Lu Xiaoning Wang Xianliang Cui Jifang Li Jin Xu Peng Xu Jinpeng Wan Source Type: research
Byrsonima sericea Ethanol Extract Protected PC12 Cells from the Oxidative Stress and Apoptosis Induced by 6-Hydroxydopamine
This study aimed to evaluate the cytoprotective activity of the B. sericea ethanolic extract (BSEE) against the cytotoxicity induced by 6-hydroxydopamine (6-OHDA) in PC12 cells, an in vitro model of parkinsonism. The identification of phenolic compounds in the extract by HPLC-DAD revealed the presence of geraniin, rutin, isoquercetin, kaempferol 3-O-β-rutinoside, and quercetin. The BSEE (75-300 µg/mL) protected PC12 cells from toxicity induced by 6-OHDA (25 µg/mL), protected cell membrane integrity and showed antioxidant activity. BSEE was able to decrease nitrite levels, glutathione depletion, and protect cells from 6-...
Source: Neurochemical Research - September 19, 2023 Category: Neuroscience Authors: Albert Layo Costa de Assis Patricia de Ara újo Rodrigues Selene Maia de Morais Ana Livya Moreira Rodrigues Jessica Maria Pessoa Gomes Tyciane de Souza Nascimento Alfaete Vieira Oliveira Mayara Sandrielly Soares de Aguiar Geanne Matos de Andrade Source Type: research
Exploring the Synthetic and Antioxidant Potential of 1,2-Disubstituted Benzimidazoles using Et3NHHSO4 Ionic Liquid Catalyst
Chem Biodivers. 2023 Sep 17:e202301159. doi: 10.1002/cbdv.202301159. Online ahead of print.ABSTRACTAn [Et3NH][HSO4] ionic-liquid catalyzed, intermolecular C-N bond formation for 1,2-disubstituted benzimidazole synthesis was achieved by the reaction of OPD and substituted aldehydes at ambient reaction conditions. Operational simplicity, use of easily available substrate and reagents, good yield in short reaction time, simple work-up, and column chromatographic free synthesis are remarkable features of this new protocol. The applicability of [Et3NH][HSO4] ionic-liquid as a green and inexpensive catalyst with good recyclabili...
Source: Chemistry and Biodiversity - September 18, 2023 Category: Biochemistry Authors: Nusrat Sahiba Pankaj Teli Priyadarshi Meena Shikha Agarwal Source Type: research
Oxidative stress may be a contributing factor in fibromyalgia patients' pain mechanisms
CONCLUSIONS: Reactive oxygen species have several negative impacts on the human body. As a result of the measurements we analyzed, the relationship between FM and oxidative stress should be studied in terms of disease progression and may help improve the treatment process.PMID:37721351 | DOI:10.4081/reumatismo.2023.1550
Source: Reumatismo - September 18, 2023 Category: Rheumatology Authors: H Beyaztas S Aktas E M Guler E Ata Source Type: research
Tert-Butyl Hydroperoxide induces Ferroptosis of Bone Mesenchymal Stem cells by repressing the Prominin2/BACH1/ROS axis
CONCLUSION: Our findings revealed a mechanism that the prominin2/BACH1/ROS axis participates in BMSCs ferroptosis and the strengthening of this axis is promising to subsist BMSCs after explantation.PMID:37721001 | DOI:10.1152/ajpcell.00224.2023
Source: American Journal of Physiology. Cell Physiology - September 18, 2023 Category: Cytology Authors: Yuzhu Xu Pan Fan Xuanfei Xu Lei Liu Lele Zhang Xi Li Jiadong Wang Yuao Tao Xiaolong Li Dandan Xu Xiaohui Wang Yan Zhou Yuntao Wang Source Type: research
β-Glucan Regulates Lipopolysaccharide Induced Genotoxic Damage to The Liver through The Induction of BRCA1 Protein Expression
CONCLUSION: The results manifested that the βG is a strong inducer of the BRCA1 protein expression in the LPSinduced hepatic stress and the protein constitutes the key component of a βG mediated liver protection against an LPS-induced genotoxic and pathological damage.PMID:37718767 | DOI:10.22074/cellj.2023.1989382.1226
Source: Cancer Control - September 18, 2023 Category: Cancer & Oncology Authors: G özde Aydoğan Kılıç Mojahed Alsafi Source Type: research
Fe-NPs and Zn-NPs: Advancing Aquaculture Performance Through Nanotechnology
Biol Trace Elem Res. 2023 Sep 18. doi: 10.1007/s12011-023-03850-6. Online ahead of print.ABSTRACTAquaculture is a growing industry facing several challenges, including disease control, water quality management, and sustainable feed production. One potential solution to these challenges is the use of trace elements such as iron (Fe) and zinc (Zn), either in their conventional form or as nanoparticles (NPs). Aquatic animals need these micronutrients for normal growth, physiological processes, and overall health. In marine species, iron boosts development, immunity, and disease resistance. At the same time, zinc enhances meta...
Source: Biological Trace Element Research - September 18, 2023 Category: Biology Authors: Farkhanda Asad Navaira Batool Aiman Nadeem Shehar Bano Noshaba Anwar Rafia Jamal Shahbaz Ali Source Type: research
Biochar supported nano core-shell (TiO < sub > 2 < /sub > /CoFe < sub > 2 < /sub > O < sub > 4 < /sub > ) for wastewater treatment
Environ Res. 2023 Sep 16:117169. doi: 10.1016/j.envres.2023.117169. Online ahead of print.ABSTRACTThe porous structure of biochar, its large surface area, and its anti-oxidant properties are extensively used for pollutant removal strategies. The literature to date has reported that the biochar assisted metal-oxide core-shells have a dominating degradation ability under solar irradiation. Therefore, this study is significantly focused on cinnamon biochar as an active anti-oxidant agent incorporated in titania-cobalt ferrite nanocore-shell (Biochar/TiO2/CoFe2O4) structures for the first time in wastewater treatment against c...
Source: Environmental Research - September 18, 2023 Category: Environmental Health Authors: Sultan Alomairy Lalitha Gnanasekaran Saravanan Rajendran Walaa F Alsanie Source Type: research
Climbazole causes cell apoptosis and lipidosis in the liver of grass carp
In this study, grass carp (Ctenopharyngodon idella) and liver cell lines (L8824 cells) were treated with climbazole at concentrations ranging from 0.2 to 20 μg/L for 42 days in vivo and 24 h in vitro to evaluate the effects on the liver, respectively. Pathological, biochemical, and gene transcription and expression analyses were conducted to examine the hepatotoxicity. Our results showed that climbazole significantly decreased the hepatosomatic index, caused cell apoptosis in vivo and in vitro, and finally accumulated lipids in the liver. Beside, climbazole increased ROS levels, reduced Nrf2 and Keap1 mRNA and protein lev...
Source: Aquatic Toxicology - September 18, 2023 Category: Toxicology Authors: Zhi-Jie Lu Wen-Jun Shi Fang-Zhou Gao Dong-Dong Ma Jin-Ge Zhang Si-Ying Li Xiao-Bing Long Qian-Qian Zhang Guang-Guo Ying Source Type: research
Tert-Butyl Hydroperoxide induces Ferroptosis of Bone Mesenchymal Stem cells by repressing the Prominin2/BACH1/ROS axis
CONCLUSION: Our findings revealed a mechanism that the prominin2/BACH1/ROS axis participates in BMSCs ferroptosis and the strengthening of this axis is promising to subsist BMSCs after explantation.PMID:37721001 | DOI:10.1152/ajpcell.00224.2023
Source: Am J Physiol Cell Ph... - September 18, 2023 Category: Cytology Authors: Yuzhu Xu Pan Fan Xuanfei Xu Lei Liu Lele Zhang Xi Li Jiadong Wang Yuao Tao Xiaolong Li Dandan Xu Xiaohui Wang Yan Zhou Yuntao Wang Source Type: research
In silico and in vitro evaluation of a safety profile of a cosmetic ingredient: 4-methoxychalcone (4-MC)
Toxicol In Vitro. 2023 Sep 16:105696. doi: 10.1016/j.tiv.2023.105696. Online ahead of print.ABSTRACTChalcone is an important scaffold within medicinal and cosmetic chemistry. The structure enables multiple modifications which may result in obtaining compounds with desirable bioactivity. One of the chalcone derivatives, 4-methoxychalcone is a known cosmetic ingredient indexed in Cosing database as an antioxidant, bleaching, and skin conditioning substance. We investigated its in silico and in vitro safety profile. In silico study using Derek Nexus showed its potential of skin sensitisation, equivocal nature of chromosome da...
Source: Toxicology in Vitro - September 18, 2023 Category: Toxicology Authors: Agnieszka Gunia-Krzy żak Justyna Popi ół Karolina S łoczyńska Dorota Żelaszczyk Katarzyna Orze ł Paulina Koczurkiewicz-Adamczyk Katarzyna W ójcik-Pszczoła Patryk Kasza Magda Borczuch-Kosta ńska El żbieta Pękala Source Type: research
Ligustilide-loaded liposome ameliorates mitochondrial impairments and improves cognitive function via the PKA/AKAP1 signaling pathway in a mouse model of Alzheimer's disease
CONCLUSION: Liposome packaging for LIG is relatively biosafe and can overcome the instability of LIG. LIG alleviates mitochondrial dysfunctions and cognitive impairment via the PKA/AKAP1 signaling pathway. Our results provide experimental evidence that LIG-LPs may be a promising agent for AD therapy.PMID:37718506 | DOI:10.1111/cns.14460
Source: CNS Neuroscience and Therapeutics - September 18, 2023 Category: Neuroscience Authors: Qi Zhang Xiangxiang Zhang Bing Yang Yan Li Xue-Heng Sun Xiang Li Ping Sui Yi-Bin Wang Shu-Yu Tian Chun-Yan Wang Source Type: research
Air nanobubble water improves plant uptake and tolerance toward cadmium in phytoremediation
This study found that diluted air NBs (25% concentration) boosted cadmium uptake of A. philoxeroides by 17.39%. They also enhanced growth (25-50%) and photosynthetic pigments (10-20%) even at low cadmium levels (0.1 mM). Furthermore, the incorporation of 25% air NBs has been demonstrated to significantly amplify the performance of key antioxidant enzymes, such as superoxide dismutase and catalase, alongside heightened levels of crucial antioxidants such as malondialdehyde. This heightened activity of antioxidant defenses offers a compelling explanation for the potential amelioration of cadmium toxicity and concurrent enhan...
Source: Environmental Pollution - September 18, 2023 Category: Environmental Health Authors: Dajiang Yan Shan Xue Zhibin Zhang Guodong Xu Yanhao Zhang Jianan Gao Wen Zhang Source Type: research
Protective effect of cornuside on OGD/R injury in SH-SY5Y cells and its underlying mechanism
In this study, we treated SH-SY5Y cells with OGD/R to simulated ischemia/reperfusion (I/R) injury. Using high-throughput transcriptome sequencing, differentially expressed genes were analyzed in the OGD/R group versus the OGD/R + Cornuside (10 μmol/L) group to explore the neuroprotective mechanisms of Cornuside. The differentially expressed genes were mainly enriched in apoptosis signaling pathway, cell cycle, DNA damage and repair, and p38/JNK MAPK and p53 signaling pathways. The results showed that OGD/R significantly reduced the survival of SH-SY5Y cells, induced apoptosis, disrupted the nucleus, promoted the release o...
Source: Brain Research - September 18, 2023 Category: Neurology Authors: Xinyu Wang Chao Yan Chaoyun Wang Xiaoyan Xu Zhihao Liu Wang Xin Jianwei Gong Source Type: research
