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Condition: Stroke
Infectious Disease: Hepatitis

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Total 168 results found since Jan 2013.

Platelet-Secreted MicroRNA-223 Promotes Endothelial Cell Apoptosis Induced by Advanced Glycation End Products via Targeting the Insulin-like Growth Factor 1 Receptor.
In conclusion, our study presents the first evidence, to our knowledge, that platelet-released miR-223 promotes advanced glycation end product-induced vascular endothelial cell apoptosis via targeting insulin-like growth factor 1 receptor. PMID: 24307738 [PubMed - as supplied by publisher]
Source: Journal of Immunology - December 4, 2013 Category: Allergy & Immunology Authors: Pan Y, Liang H, Liu H, Li D, Chen X, Li L, Zhang CY, Zen K Tags: J Immunol Source Type: research

Antivirals for HCV improve kidney and cardiovascular diseases in diabetic patients
(Wiley) Researchers from Taiwan reveal that antiviral therapy for hepatitis C virus (HCV) improves kidney and cardiovascular outcomes for patients with diabetes. Results of the study published in Hepatology, a journal of the American Association for the Study of Liver Diseases, show that incidences of kidney disease, stroke, and heart attack were lower in patients treated with pegylated interferon and ribavirin compared to HCV patients not treated with antivirals or diabetic patients not infected with the virus.
Source: EurekAlert! - Infectious and Emerging Diseases - December 11, 2013 Category: Infectious Diseases Source Type: news

Table of Contents
Abstract Long QT syndrome more likely in patients with HIV, hepatitis C Long‐term treatments for obesity yield results with lifestyle changes Interaction of valproic acid with two drugs Topiramate study signals possible treatment for cocaine dependence Adjunctive modafinil improves depression, lessens fatigue D‐cycloserine, exposure therapy promising for treating PTSD Gabapentin results bode well for alcohol treatment by MDs Vortioxetine shows efficacy in treating major depression Better trials needed for SSRIs in stroke recovery Drug Safety Communication
Source: The Brown University Psychopharmacology Update - February 12, 2014 Category: Psychiatry Source Type: research

What Causes Ataxia?
Discussion Coordination and balance problems are caused by various problems affecting the central and peripheral nervous system. Normal development of a child or weakness of a child are commonly mistaken for true ataxia. Ataxia specifically refers to “…impairment of the coordination of movement without loss of muscle strength.” If it is purely due to abnormalities of the cerebellum then there should be no changes in mental status, sensation or weakness. Sometimes it is difficult to determine if there are abnormalities in other areas. For example, Guillian-Barre often presents with difficulty or clumsy wal...
Source: PediatricEducation.org - March 31, 2014 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

A Case Of Hemophagocytic Lymphohistiocytosis Syndrome In A Patient With Multiple Sclerosis On Fingolimod Therapy. (P2.206)
CONCLUSIONS:As far as we know, this syndrome has never been reported in fingolimod treated patients. EBV reactivation may have been the triggering factor of HLH in our patient. Whether fingolimod contributed to HLH, through a direct mechanism, or indirectly favoring EBV reactivation, remains unknown. Our case highlights the diagnostic challenge of HLH and the need of monitoring and reporting serious adverse events in patients exposed to new IMD. Study Supported by:Disclosure: Dr. Abreu has received personal compensation for activities with Bayer Pharmaceuticals Corporation, Novartis, and Biogen Idec. Dr. Peixoto has nothin...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Abreu, P., Peixoto, C., Carvalho, C., Santos, L., Sarmento, A., Jose Sa, M. Tags: MS and CNS Inflammatory Disease: Treatment Safety Source Type: research

Association between nutrition and the evolution of multimorbidity: The importance of fruits and vegetables and whole grain products
Summary: Background & aims: Multimorbidity is a common health status. The impact of nutrition on the development of multimorbidity remains to be determined. The aim of this study is to determine the association between foods, macronutrients and micronutrients and the evolution of multimorbidity.Methods: Data from 1020 Chinese who participated in the Jiangsu longitudinal Nutrition Study (JIN) were collected in 2002 (baseline) and 2007 (follow-up). Three-day weighted food records and status for 11 chronic diseases was determined using biomedical measures (hypertension, diabetes, hypercholesterolemia and anemia) or self-repor...
Source: Clinical Nutrition - July 24, 2013 Category: Nutrition Authors: Guillaume Ruel, Zumin Shi, Shiqi Zhen, Hui Zuo, Edeltraut Kröger, Caroline Sirois, Jean-Frédéric Lévesque, Anne W. Taylor Tags: Original Articles Source Type: research

Annals of Internal Medicine tip sheet for June 17, 2014
(American College of Physicians) The June 17, 2014, issue of Annals of Internal Medicine includes the following articles: 'To prevent stroke in women, start young' and 'Liver cancer screening may not increase survival in chronic hepatitis C.'
Source: EurekAlert! - Cancer - June 16, 2014 Category: Cancer & Oncology Source Type: news

Glycyrrhizin protects brain against ischemia-reperfusion injury in mice through HMGB1-TLR4-IL-17A signaling pathway.
Abstract High mobility group box 1 (HMGB1)-Toll-like receptor 4 (TLR4) signaling has been recently found to induce interleukin (IL)-17A secretion in drug-induced hepatitis and myocardial I/R injury. The purpose of this study is to evaluate whether HMGB1-TLR4 signaling could induce IL-17A secretion and lead to brain I/R injury. We also sought to investigate whether glycyrrhizin elucidated its neuroprotective effects through HMGB1-TLR4-IL-17A signaling pathway. Various biochemical estimations, neurological status, and assessment of cerebral infarct size were carried out 72h after middle cerebral artery occlusion (MC...
Source: Brain Research - August 8, 2014 Category: Neurology Authors: Zhang J, Wu Y, Weng Z, Zhou T, Feng T, Lin Y Tags: Brain Res Source Type: research

Environmental chemicals mediated the effect of old housing on adult health problems: US NHANES, 2009-2010.
Abstract Housing conditions affect occupants continuously, and health interventions have shown a positive association between housing investment or improvement and occupant's health. However, the sources of the housing problems were less understood. Since it was observed that lead dust and chloroanisoles released from housing (materials) as indoor pollutants affected child's health, we now aimed to examine the relationships among built year, environmental chemicals and individual health in adults in a national and population-based setting. Data were retrieved from the US National Health and Nutrition Examination S...
Source: Environmental Science and Pollution Research International - August 21, 2014 Category: Environmental Health Authors: Shiue I, Bramley G Tags: Environ Sci Pollut Res Int Source Type: research

HCV, but not HIV, is a risk factor for cerebral small vessel disease
Conclusions: This tissue-based analysis of cerebral arteriolar disease demonstrates that HCV constitutes an independent risk, in addition to African American race, hypertension, and cART. Further study is needed to understand what aspects of HCV and cART contribute to cerebrovascular neuropathogenesis.
Source: Neurology Neuroimmunology and Neuroinflammation - September 4, 2014 Category: Neurology Authors: Morgello, S., Murray, J., Van Der Elst, S., Byrd, D. Tags: Other cerebrovascular disease/ Stroke, HIV Article Source Type: research

CDC National Health Report: Leading Causes of Morbidity and Mortality and Associated Behavioral Risk and Protective Factors-United States, 2005-2013.
This report reviews population health in the United States and provides an assessment of recent progress in meeting high-priority health objectives. The health status indicators described in this report were selected because of their direct relation to the leading causes of death and other substantial sources of morbidity and mortality and should be the focus of prevention efforts. REPORTING PERIOD COVERED: Data are reported starting in 2005 (or the earliest available year since 2005) through the current data year. Because data sources and specific indicators vary regarding when data are available, the most recent yea...
Source: MMWR Surveill Summ - October 31, 2014 Category: Epidemiology Authors: Johnson NB, Hayes LD, Brown K, Hoo EC, Ethier KA Tags: MMWR Surveill Summ Source Type: research

Ten-point plan to tackle liver disease published
"Doctors call for tougher laws on alcohol abuse to tackle liver disease crisis," The Guardian reports. But this is just one of 10 recommendations for tackling the burden of liver disease published in a special report in The Lancet.The report paints a grim picture of an emerging crisis in liver disease in the UK, saying it is one of the few countries in Europe where liver disease and deaths have actually increased rapidly over the last 30 years. It concludes with 10 recommendations to tackle the burden of liver disease.The media has approached the recommendations from many different angles, with many sources only ...
Source: NHS News Feed - November 27, 2014 Category: Consumer Health News Tags: Food/diet Lifestyle/exercise QA articles Source Type: news

Clinical Reasoning: A 28-year-old man with progressive gait disturbance and encephalopathy
A 28-year-old man with sickle cell disease presented with 7 months of difficulty walking. Initial examination 3 months prior to admission to our hospital was thought to be consistent with a polyneuropathy. He was areflexic, was unable to stand on toes or heels with decreased sensation on the left foot to light touch and vibration, had difficulty with heel to shin, and was unable to perform tandem gait. Laboratory tests revealed anemia (hemoglobin 7.2 g/dL) and elevated creatinine (1.49 g/dL). HIV, antinuclear antibodies, antineutrophil cytoplasmic antibodies, hepatitis serologies, rapid plasma reagin, thyroid-stimulating h...
Source: Neurology - December 8, 2014 Category: Neurology Authors: Massaro, A. M., Pruitt, A. Tags: Stroke in young adults, MRI, Gait disorders/ataxia, All Oncology RESIDENT AND FELLOW SECTION Source Type: research

Syphilis on the Rise: Diagnosis, Treatment, and Prevention
This article focuses on identifying high-risk patients and diagnosis and treatment options for syphilis infection.
Source: The Journal for Nurse Practitioners - January 1, 2015 Category: Nursing Authors: Jennifer Klein, Mary McLaud, Deanna Rogers Tags: Feature Article Source Type: research

What is the Remission Rate for Antithyroid Drug Treatment for Hyperthyroidism in Children?
Discussion The thyroid gland secrets two hormones – T4 which is a prohormone and T3 which is the biologically active hormone. Receptors for T3 are found in nearly all body tissues. T3 regulates metabolism and energy production. Organs most affected are the heart, liver and central nervous system as well as growth of the fetus and child. Hyperthyroidism is common with a prevalence rate of about 1-2% for women and 0.2% for men. The most common cause of thyrotoxicosis is Grave’s disease where autoantibodies to thyroid stimulating hormone (TSH) exist. These autoantibodies attach to thyroid tissue TSH receptors and...
Source: PediatricEducation.org - January 26, 2015 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news