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Specialty: Urology & Nephrology
Condition: Hypertension

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Total 232 results found since Jan 2013.

Kidney dysfunction is associated with risk of cardiovascular events in middle-aged and elderly population with hypertension: A  5-year community-based cohort study in China
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CONCLUSION: Moderate to severe kidney dysfunction was an independent risk predictor of CVD events. Among subjects with hypertension or poorly controlled blood pressure level, the presence of CKD significantly increased the risks of CVD events and stroke.
. PMID: 31983380 [PubMed - as supplied by publisher]
Source: Clinical Nephrology - January 26, 2020 Category: Urology & Nephrology Authors: Gu X, Fang X, Ji X, Tang Z, Wang C, Guan S, Wu X, Liu H, Zhang Z Tags: Clin Nephrol Source Type: research

Selected cardiovascular risk factors in early stages of chronic kidney disease
AbstractCardiovascular diseases, including hypertension, congestive heart failure, myocardial infarction, stroke and atherosclerosis, are common in patients with chronic kidney disease. Aside from the standard biomarkers, measured to determine cardiovascular risk, new ones have emerged: markers of oxidative stress, apoptosis, inflammation, vascular endothelium dysfunction, atherosclerosis, organ calcification and fibrosis. Unfortunately, their utility for routine clinical application remains to be elucidated. A causal relationship between new markers and cardiovascular diseases in patients with chronic kidney disease remai...
Source: International Urology and Nephrology - January 17, 2020 Category: Urology & Nephrology Source Type: research

The association between CHA2DS2-VASc score and erectile dysfunction: a cross-sectional study
Conclusion: CHA2DS2-VASc score can be used to detect Erectile dysfunction in patients who are admitted to the cardiology outpatient clinics.
Source: International Braz J Urol - December 20, 2019 Category: Urology & Nephrology Source Type: research

Impact of Cardio-Renal-Metabolic Comorbidities on Cardiovascular Outcomes and Mortality in Type 2 Diabetes Mellitus.
CONCLUSION: In T2DM patients, CKD presence was associated with higher risk of modified MACE, HF, and ACM. This may have risk-stratification implications for T2DM patients based on background CKD and highlights the potential importance of novel renoprotective strategies. PMID: 31812955 [PubMed - as supplied by publisher]
Source: American Journal of Nephrology - December 5, 2019 Category: Urology & Nephrology Authors: Cherney DZI, Repetto E, Wheeler DC, Arnold SV, MacLachlan S, Hunt PR, Chen H, Vora J, Kosiborod M Tags: Am J Nephrol Source Type: research

Potassium binding for conservative and preservative management of chronic kidney disease
In conclusion, there are new well tolerated and effective K+-binding agents for acutely and chronically managing hyperkalemia.
Source: Current Opinion in Nephrology and Hypertension - November 29, 2019 Category: Urology & Nephrology Tags: NOVEL THERAPEUTIC APPROACHES IN NEPHROLOGY AND HYPERTENSION: Edited by Kamyar Kalantar-Zadeh and Ekamol Tantisattamo Source Type: research

Prevention and treatment of stroke in patients with chronic kidney disease: an overview of evidence and current guidelines
Chronic Kidney Disease (CKD) is strongly associated with an increased risk of stroke, small vessel disease, and vascular dementia. Common vascular factors for stroke, such as hypertension, diabetes, and atrial fibrillation, are more prevalent in CKD patients, accounting for this association. However, factors unique to these patients, such as uraemia, oxidative stress, mineral and bone abnormalities, as well as dialysis-related factors are also believed to contribute to risk. Despite improvements in stroke treatment and survival in the general population, the rate of improvement in patients with CKD, especially those who ar...
Source: Kidney International - October 17, 2019 Category: Urology & Nephrology Authors: Dearbhla M. Kelly, Peter M. Rothwell Tags: Review Source Type: research

Chronic disease burdens of incident U.S.  dialysis patients, 1996 - 2015
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DISCUSSION: Mortality and cardiovascular disease burden have declined for dialysis patients in the United States despite an aging population that is increasingly hypertensive and diabetic. Comorbid disease burdens among HD and PD patients have diverged over time, with PD patients having fewer comorbid conditions.
. PMID: 31599226 [PubMed - as supplied by publisher]
Source: Clinical Nephrology - October 9, 2019 Category: Urology & Nephrology Authors: McGill RL, Bragg-Gresham JL, He K, Lacson EK, Miskulin DC, Saran R Tags: Clin Nephrol Source Type: research

Serum lipoprotein(a) and risk of hemorrhagic stroke among incident peritoneal dialysis patients: a large study from a single center in China.
Conclusions: Among patients with incident PD, a higher serum Lp(a) level may predict a lower risk of hemorrhagic stroke. PMID: 31498021 [PubMed - in process]
Source: Renal Failure - September 10, 2019 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

The Renal Molecular Clock: Broken by Aging and Restored by Exercise.
Abstract The mammalian circadian clock governs physiological, endocrine, and metabolic responses coordinated in a 24h rhythmic pattern by the suprachiasmatic nucleus (SCN) of the anterior hypothalamus. The SCN also dictates circadian rhythms in peripheral tissues like the kidney. The kidney has several important physiological functions including removing waste and filtering the blood, regulation of: fluid volume, blood osmolarity, blood pressure and calcium metabolism, all of which are under tight control of the molecular/circadian clock. Normal aging has a profound influence on both renal function, central and pe...
Source: Am J Physiol Renal P... - August 27, 2019 Category: Urology & Nephrology Authors: Schmitt EE, Johnson EC, Yusifova M, Bruns DR Tags: Am J Physiol Renal Physiol Source Type: research

The Case | Severe hypertension and hyperkalemia in a kidney transplant recipient
A 55-year-old man with a history of end-stage renal disease due to autosomal dominant polycystic kidney disease and bilateral nephrectomy without adrenalectomy underwent his first kidney transplantation after 6 years of hemodialysis. The patient had no history of donor-specific antibodies. The donor was described as a 69-year-old man with a history of active smoking and  aortic valvulopathy who died of a stroke without cardiac arrest or collapse. Maintenance immunosuppressive therapy consisted of low-dose tacrolimus and everolimus.
Source: Kidney International - July 19, 2019 Category: Urology & Nephrology Authors: Vincent Dupont, Charlotte Colosio, Marguerite Hureaux, Laetitia Mokri, Betoul Schvartz, Vincent Vuiblet, Antoine Braconnier, Rosa Vargas-Poussou, Philippe Rieu Tags: Make Your Diagnosis Source Type: research

Free 25-Vitamin D Is Correlated with Cardiovascular Events in Prevalent Hemodialysis Patients but Not with Markers of Renal Mineral Bone Disease
In conclusion, our study shows that free vitamin D serum concentrations are independently associated with major cardiovascular events in chronic kidney disease patients on dialysis.Kidney Blood Press Res
Source: Kidney and Blood Pressure Research - June 14, 2019 Category: Urology & Nephrology Source Type: research

Intensive versus Usual Control of Hypertension in the Prevention of Cardiovascular and Renal Outcomes: A Cumulative Meta-Analysis of Randomized Controlled Trials
Conclusion: The findings of this study suggest that IBP control plays a beneficial role in the prevention of some major cardiovascular events, including myocardial infarction, stroke, and albuminuria.Kidney Blood Press Res
Source: Kidney and Blood Pressure Research - May 10, 2019 Category: Urology & Nephrology Source Type: research

Stroke and renal artery stenosis from Takayasu's arteritis diagnosed in a 57-year-old male patient.
We report a case of a 57-year-old male patient with late diagnosis of TA and various related complications including stroke in the left middle cerebral artery territory, predominant left renal artery stenosis, and hypertension with discrepancy of blood pressure between two arms due to predominant left subclavian artery stenosis. Thus, physicians should keep in their mind this late presentation after the age of 40 years. The aim is to increase the awareness of this condition because of early diagnosis and the timely introduction of treatment can lead to improved outcomes in this poorly understood clinical enigma. PMID:...
Source: Saudi Journal of Kidney Diseases and Transplantation - April 30, 2019 Category: Urology & Nephrology Authors: Ur Rahman SS, Al Shehri A, Al Ghamdi M, Al Shareef M Tags: Saudi J Kidney Dis Transpl Source Type: research

The Impact of APOL1 on Chronic Kidney Disease and Hypertension
This article reviews relationships between mild to moderate essential hypertension and chronic kidney disease with a focus on the role of APOL1 in development of hypertension. Available evidence strongly supports that APOL1 renal-risk variants associate with glomerulosclerosis in African Americans, which then causes secondary hypertension, not with essential hypertension per se.
Source: Advances in Chronic Kidney Disease - April 24, 2019 Category: Urology & Nephrology Source Type: research

Recent evidence for direct oral anticoagulants in chronic kidney disease
Purpose of review The direct oral anticoagulants (DOACs) have emerged as an effective and safe alternative to vitamin K antagonists (VKAs) for stroke and venous thromboembolism (VTE) prevention. However, patients with chronic kidney disease (CKD) experience an increase in the risk of both thromboembolism and bleeding, and the risk–benefit profile of DOACs, particularly in advanced CKD remains a source of ongoing debate. This review summarizes the recent evidence on the effects of DOACs in CKD across a range of clinical indications including newly emerging indications. Recent findings Data on early-to-moderate stage ...
Source: Current Opinion in Nephrology and Hypertension - April 4, 2019 Category: Urology & Nephrology Tags: EPIDEMIOLOGY AND PREVENTION: Edited by Navdeep Tangri Source Type: research