Intensive versus Usual Control of Hypertension in the Prevention of Cardiovascular and Renal Outcomes: A Cumulative Meta-Analysis of Randomized Controlled Trials

Conclusion: The findings of this study suggest that IBP control plays a beneficial role in the prevention of some major cardiovascular events, including myocardial infarction, stroke, and albuminuria.Kidney Blood Press Res
Source: Kidney and Blood Pressure Research - Category: Urology & Nephrology Source Type: research

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WEDNESDAY, Oct. 16, 2019 (American Heart Association News) -- Many people know treating high blood pressure reduces the odds of a heart attack, stroke or heart failure. Now, a new study suggests another added benefit: a lower risk of lesions in the...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
AbstractRecent FindingsEssential hypertension is the main determinant of cardiovascular morbidity and mortality worldwide. During the last decades, several antihypertensive drug therapies have been introduced and tested in clinical trials, both as monotherapies and combination therapies. The current recommended therapeutic approaches effectively reduce the lifetime risk of experiencing major cardiovascular outcomes and disabling comorbidities, such as myocardial infarction, stroke, and congestive heart failure. On the basis of multiple proofs, antihypertensive therapy is currently recommended for improving event-free survi...
Source: Current Hypertension Reports - Category: Primary Care Source Type: research
When counseling patients regarding the potential benefits of parathyroidectomy for primary hyperparathyroidism (PHPT), surgeons discuss the possible short-term and long-term consequences of operation. The short-term benefits may include alleviation of fatigue, bone aches, depressed mood, and frequent urination. While it is extremely rewarding to improve these symptoms, it is the long-term benefits that may be truly life-altering and potentially lifesaving. The organs most likely to be negatively affected by PHPT are the bones, kidneys, brain, and heart. Medical students everywhere still learn about the effects of this dise...
Source: JAMA Surgery - Category: Sports Medicine Source Type: research
Hypertension is a major risk factor for the development of cardiovascular disease morbidity and mortality worldwide. Stroke, heart failure, myocardial infarction, and peripheral arterial disease are all outcomes associated with hypertension in adults. Hypertension is also considered to be a major cause of poorer disability-adjusted life-years. The prevalence of hypertension in adults has been debated in part because the definition of hypertension has changed over time. The association between blood pressure and cardiovascular disease is a continuous one, making the establishment of a cut point for hypertension difficult. H...
Source: JAMA Pediatrics - Category: Pediatrics Source Type: research
Fitbit or Apple Watch for running? Garmin or Misfit for swimming? Sleep Cycle or Sleep as Android for sleep tracking? What about measuring heart rate, blood pressure, or tracking how to cut out stress from your life? Dozens of gadgets on the healthcare wearable market promise you a healthier lifestyle, but it’s easy to go astray in the jungle of digital health gadgets. Let me show you my top choices when it comes to health wearables and trackers. Guidance in the health wearable universe By now, I have tested and used more than a hundred devices and gadgets that measure health parameters or vital signs. Thus,...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Health Sensors & Trackers Portable Diagnostics activity fitness fitness trackers Health 2.0 Healthcare Innovation meditation mental health Personalized medicine sleep sleep optimization sleep tracking stress technology wear Source Type: blogs
CONCLUSIONS: Cancer patients are vulnerable to comorbidity related to heart and cerebral disease. The influence of comorbidities on prognosis is noticeable and specific both for the type of cancer and comorbidities. PMID: 31562288 [PubMed - as supplied by publisher]
Source: Aging - Category: Biomedical Science Authors: Tags: Aging (Albany NY) Source Type: research
One of the earliest Cochrane Reviews on high blood pressure was first published in 1998, investigating treatments for the elderly. It was substantively updated for a second time in June 2019 and we asked the lead author, Vijaya Musini, from the University of British Columbia in Vancouver Canada to tell us about the evidence.High blood pressure or hypertension, which is defined as systolic blood pressure of 140 mm of mercury or more, or diastolic blood pressure of 90 mm of mercury or more, increases with age, particularly in those over 60. It raises the risk of heart attack and stroke, with systolic hypertension, which is m...
Source: Cochrane News and Events - Category: Information Technology Authors: Source Type: news
In this study, researchers studied 438,952 participants in the UK Biobank, who had a total of 24,980 major coronary events - defined as the first occurrence of non-fatal heart attack, ischaemic stroke, or death due to coronary heart disease. They used an approach called Mendelian randomisation, which uses naturally occurring genetic differences to randomly divide the participants into groups, mimicking the effects of running a clinical trial. People with genes associated with lower blood pressure, lower LDL cholesterol, and a combination of both were put into different groups, and compared against those without thes...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
We examined human lung tissue from COPD patients and normal control subjects, and found a substantial increase in p16-expressing alveolar cells in COPD patients. Using a transgenic mouse deficient for p16, we demonstrated that lungs of mice lacking p16 were structurally and functionally resistant to CS-induced emphysema due to activation of IGF1/Akt regenerative and protective signaling. Fat Tissue Surrounds Skeletal Muscle to Accelerate Atrophy in Aging and Obesity https://www.fightaging.org/archives/2019/09/fat-tissue-surrounds-skeletal-muscle-to-accelerate-atrophy-in-aging-and-obesity/ Researchers her...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
We describe the prevalence, hazard ratios (HRs), and population-attributable fractions (PAFs) for cardiovascular disease and mortality associated with a cluster of behavioural factors (ie, tobacco use, alcohol, diet, physical activity, and sodium intake), metabolic factors (ie, lipids, blood pressure, diabetes, obesity), socioeconomic and psychosocial factors (ie, education, symptoms of depression), grip strength, and household and ambient pollution. Associations between risk factors and the outcomes were established using multivariable Cox frailty models and using PAFs for the entire cohort, and also by countries grouped ...
Source: The Lancet - Category: General Medicine Source Type: research
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