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Condition: Cirrhosis
Infectious Disease: Hepatitis

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Total 22 results found since Jan 2013.

The Paradoxical Protective Effect of Liver Steatosis on Severity and Functional Outcome of Ischemic Stroke
Conclusions: Our study shows that a higher burden of liver steatosis seems to be associated with less severe stroke and better functional outcome after ischemic stroke or TIA. Introduction Non-alcoholic fatty liver disease (NAFLD) is a spectrum of diseases from simple steatosis to steatohepatitis with varying degree of fibrosis, and liver cirrhosis (1, 2). NAFLD is becoming the most common chronic liver disease worldwide including Korea, affecting approximately 25% of the general population (3, 4). NAFLD is closely associated with obesity, insulin resistance, and type 2 diabetes mellitus, and is even recognized as ...
Source: Frontiers in Neurology - April 11, 2019 Category: Neurology Source Type: research

Ischemic stroke in liver cirrhosis: epidemiology, risk factors, and in-hospital outcomes
Conclusion Ischemic stroke was often observed in patients with cirrhosis, and it significantly increased the in-hospital mortality. The association of inflammation, coagulation disorders, and viral hepatitis with development of ischemic stroke in liver cirrhosis should be further evaluated in prospective cohort studies.
Source: European Journal of Gastroenterology and Hepatology - December 22, 2017 Category: Gastroenterology Tags: Original Articles: Liver Cirrhosis Source Type: research

Impact of virus clearance for the development of hemorrhagic stroke in chronic hepatitis C
In conclusion, HCV clearance reduced the development of intracerebral hemorrhagic stroke. In particular, HCV clearance reduced intracerebral hemorrhagic stroke to about one‐fourth in cirrhotic patients. J. Med. Virol. © 2013 Wiley Periodicals, Inc.
Source: Journal of Medical Virology - October 24, 2013 Category: Virology Authors: Yasuji Arase, Mariko Kobayashi, Yusuke Kawamura, Fumitaka Suzuki, Yoshiyuki Suzuki, Norio Akuta, Masahiro Kobayashi, Hitomi Sezaki, Satoshi Saito, Tetsuya Hosaka, Kenji Ikeda, Hiromitsu Kumada, Tetsuro Kobayashi Tags: Research Article Source Type: research

Risk of gallstones in patients with obstructive sleep apnea: a nationwide observational cohort study
ConclusionThe study shows a strong association between OSA and gallstones. Moreover, our findings suggest the requirement for survey and health education for gallstones in OSA and further studies to verify whether the treatment of OSA can reduce the risk of gallstones.
Source: Sleep and Breathing - July 7, 2018 Category: Respiratory Medicine Source Type: research

Risk of gallstones in patients with obstructive sleep apnea: a nationwide observational cohort study.
CONCLUSION: The study shows a strong association between OSA and gallstones. Moreover, our findings suggest the requirement for survey and health education for gallstones in OSA and further studies to verify whether the treatment of OSA can reduce the risk of gallstones. PMID: 29980983 [PubMed - as supplied by publisher]
Source: Sleep and Breathing - July 7, 2018 Category: Sleep Medicine Authors: Chen CH, Lin CL, Hsu CY, Kao CH Tags: Sleep Breath Source Type: research

HCV, but not HIV, is a risk factor for cerebral small vessel disease
Conclusions: This tissue-based analysis of cerebral arteriolar disease demonstrates that HCV constitutes an independent risk, in addition to African American race, hypertension, and cART. Further study is needed to understand what aspects of HCV and cART contribute to cerebrovascular neuropathogenesis.
Source: Neurology Neuroimmunology and Neuroinflammation - September 4, 2014 Category: Neurology Authors: Morgello, S., Murray, J., Van Der Elst, S., Byrd, D. Tags: Other cerebrovascular disease/ Stroke, HIV Article Source Type: research

Ten-point plan to tackle liver disease published
"Doctors call for tougher laws on alcohol abuse to tackle liver disease crisis," The Guardian reports. But this is just one of 10 recommendations for tackling the burden of liver disease published in a special report in The Lancet.The report paints a grim picture of an emerging crisis in liver disease in the UK, saying it is one of the few countries in Europe where liver disease and deaths have actually increased rapidly over the last 30 years. It concludes with 10 recommendations to tackle the burden of liver disease.The media has approached the recommendations from many different angles, with many sources only ...
Source: NHS News Feed - November 27, 2014 Category: Consumer Health News Tags: Food/diet Lifestyle/exercise QA articles Source Type: news

Donor risk factors in orthotopic liver transplant: analysis of the OPTN/UNOS registry.
This study of the United Network for Organ Sharing registry data analyzed reputed donor factors using the post-MELD data and evaluated them further in HCV positive and HCV negative recipients with hepatic cirrhosis to develop a modified DRI (mDRI). We found that HCV negative cirrhotic recipients have generally higher tolerance against inferior qualities of donors than HCV positive cirrhotic patients. In addition, the results revealed the post-MELD prognostic factors that should be considered in the donor procurement processes. The group of "all recipients" and the subset of HCV positive cirrhotic recipients showed a simila...
Source: Clinical Transplants - November 20, 2015 Category: Transplant Surgery Tags: Clin Transpl Source Type: research

Frequency of Cardiovascular Events and Effect on Survival in Liver Transplant Recipients for Cirrhosis Due to Alcoholic or Nonalcoholic Steatohepatitis.
CONCLUSIONS: Cardiovascular events occurred with similar frequency in transplant recipients for nonalcoholic steatohepatitis or alcoholic cirrhosis. Patient survival was affected in both groups, but male patients with concomitant hepatitis C virus infection remained at higher risk for a cardiovascular event after liver transplant. Development of a cardiac evaluation protocol for liver transplant recipients could help monitor these patients. PMID: 26581602 [PubMed - as supplied by publisher]
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - November 17, 2015 Category: Transplant Surgery Authors: Piazza NA, Singal AK Tags: Exp Clin Transplant Source Type: research

Relation Between Hepatitis C Virus Exposure and Risk of Osteoporosis: A Nationwide Population-Based Study
Abstract: The effect of hepatitis C virus (HCV) exposure on bone mineral density without advanced liver disease remains debated. Thus, we assessed the relation between HCV exposure and the risk of osteoporosis. From 2000 to 2011, patients aged>20 years with HCV exposure were identified from the Longitudinal Health Insurance Database 2000. Of the 51,535 sampled patients, 41,228 and 10,307 patients were categorized as the comparison and the HCV exposure cohorts, respectively. The overall incidence of osteoporosis in the HCV exposure cohort was higher than in the comparison cohort (8.27 vs 6.19 per 1000 person-years; crude ha...
Source: Medicine - November 1, 2015 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Imaging of a Fatal Air Embolism from ERCP (P4.363)
CONCLUSIONS: Though most of the occurrences in relation to ERCP are portal venous air embolisms, which are absorbed spontaneously, serious and sometimes fatal complications have occurred including arterial air embolisms causing multiorgan damage including cerebral infarcts. Case history, pertinent imaging and pathological findings are discussed to bring awareness of this rare complication of ERCP and emphasize its early recognition. Disclosure: Dr. Jens has nothing to disclose. Dr. Lee has nothing to disclose. Dr. Ibrahimi has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Jens, W., Lee, A., Ibrahimi, M. Tags: Cerebrovascular Case Reports Source Type: research

Prognostic value of viral eradication for major adverse cardiovascular events in hepatitis C cirrhotic patients
Conclusion In patients with compensated HCV-related cirrhosis, Asian ethnic origin, arterial hypertension, smoking and low serum albumin are independent predictive factors of cardiovascular events, while a sustained virological response is associated with a decreased rate of cardiovascular events.
Source: American Heart Journal - November 9, 2017 Category: Cardiology Source Type: research

IJERPH, Vol. 15, Pages 513: Association between Inflammatory Bowel Disease and Cholelithiasis: A Nationwide Population-Based Cohort Study
g Kao We assessed the subsequent risk of cholelithiasis development in patients with inflammatory bowel diseases (IBDs) such as Crohn’s disease (CD) or ulcerative colitis (UC). We identified 8186 patients who aged ≥20 years and were diagnosed with IBD between 2000 and 2010 as the study cohort. A total of 8186 patients without IBD were selected by frequency-matching according to age, sex, comorbidities, and the index date of diagnosis, and they were identified as the control cohort. To measure the incidence of cholelithiasis, all patients were followed up until the end of 2011. The risk of developing cholelithiasis,...
Source: International Journal of Environmental Research and Public Health - March 14, 2018 Category: Environmental Health Authors: Chien-Hua Chen Cheng-Li Lin Chia-Hung Kao Tags: Article Source Type: research

Liver Transplant in Hemoglobin SC Disease and Autoimmune Hepatitis: A Case Report
We report a case of a 50-year-old man with sickle cell disease genotype SC (HbSC) and cirrhosis secondary to autoimmune hepatitis who underwent liver transplant. His postoperative course included upper extremity deep vein thrombosis, pulmonary embolus, stroke via a patent foramen ovale after a line removal, and posterior reversible encephalopathy syndrome. Fortunately, he is alive with a functioning graft at 10 months after liver transplant. This case highlights the feasibility of liver transplant in sickle cell disease given the support of meticulous multidisciplinary care and the unique aspects of autoimmune hepatitis an...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - January 4, 2022 Category: Transplant Surgery Authors: Ahyoung Kim Naziheh Assarzadegan Robert A Anders Kiyoko Oshima Shruti Chaturvedi Sharon Weeks Ruhail Kohli Sophie Lanzkron Ahmet Gurakar Jacqueline Garonzik-Wang Po-Hung Chen Source Type: research