Filtered By:
Condition: Hyperactivity

This page shows you your search results in order of relevance. This is page number 5.

Order by Relevance | Date

Total 310 results found since Jan 2013.

Genetic variability of SRC family kinases and its association with platelet hyperreactivity and clinical outcomes: a systematic review.
CONCLUSIONS: Src family kinases are one of the most important signal transmitters in platelets. Some receptors have well documented interactions with SFKs, while other have not been examined in humans or data about its association originate from single studies. Further studies are necessary to confirm the findings and reduce false-positive associations. PMID: 29237371 [PubMed - as supplied by publisher]
Source: Current Pharmaceutical Design - December 12, 2017 Category: Drugs & Pharmacology Authors: Milanowski L, Rasul F, Natalia GS, Eyileten C, Siller-Matula J, Postula M Tags: Curr Pharm Des Source Type: research

Decompressive Craniectomy for Traumatic Brain Injury: Postoperative Cerebral Hemodynamic Evaluation
Conclusion: There is a wide heterogeneity of postoperative cerebral hemodynamic findings among TBI patients who underwent DC, including hemodynamic heterogeneity between their cerebral hemispheres. DC was proved to be effective for the treatment of cerebral oligoemia. Our data support the concept of heterogeneous nature of the pathophysiology of the TBI and suggest that DC as the sole treatment modality is insufficient. Introduction Decompressive craniectomy (DC) may effectively decrease intracranial pressure (ICP) and increase cerebral perfusion pressure (CPP) in traumatic brain injury (TBI) patients with refracto...
Source: Frontiers in Neurology - April 11, 2019 Category: Neurology Source Type: research

Decompressive Craniectomy for Traumatic Brain Injury: Postoperative TCD Cerebral Hemodynamic Evaluation
Conclusion: There is a wide heterogeneity of postoperative cerebral hemodynamic findings among TBI patients who underwent DC, including hemodynamic heterogeneity between their cerebral hemispheres. DC was proved to be effective for the treatment of cerebral oligoemia. Our data support the concept of heterogeneous nature of the pathophysiology of the TBI and suggest that DC as the sole treatment modality is insufficient. Introduction Decompressive craniectomy (DC) may effectively decrease intracranial pressure (ICP) and increase cerebral perfusion pressure (CPP) in traumatic brain injury (TBI) patients with refracto...
Source: Frontiers in Neurology - April 11, 2019 Category: Neurology Source Type: research

Subclinical Atherosclerosis in Primary Sj ögren's Syndrome: Does Inflammation Matter?
Conclusions The markers of endothelial activation and damage and of chronic inflammation investigated until now failed to result predictors of subclinical atherosclerosis or to be associated with increased risk of CV events in SS patients. This may suggest that other mechanisms are implicated with increased prevalence of subclinical atherosclerosis in SS or that these biomarkers exert a different mechanism in the pathogenesis of endothelial damage and in the induction of atherosclerosis. Surely, the relationship between the disease itself and inflammatory and immune dysfunction factors is quite complex and still to be cla...
Source: Frontiers in Immunology - April 16, 2019 Category: Allergy & Immunology Source Type: research

Why is Clinical fMRI in a Resting State?
Conclusions Despite some perceived impediments to expanding clinical rs-fMRI use, neuroradiologists were generally enthusiastic about rs-fMRI in research and clinical applications, believing that their current workplace MRI systems are suitable for rs-fMRI acquisition. Many of the concerns associated with using rs-fMRI in clinical contexts are related to: (1) developing better methods for minimizing physiological noise effects, (2) improving methods for detecting the spatial characteristics of clinically-relevant brain processing systems in individual patients, and (3) overcoming remaining standardization, training, and r...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

Is Aberrant Reno-Renal Reflex Control of Blood Pressure a Contributor to Chronic Intermittent Hypoxia-Induced Hypertension?
This study demonstrated unaltered vascular conductance in response to lumbar sympathetic stimulation in CIH-exposed rats. Aortic compliance was increased and estimated blood volume was unchanged in CIH-exposed rats. Increased blood pressure was related to an increase in cardiac output, which was confirmed by echocardiography (Lucking et al., 2014). It is suggested therefore that hypertension in the CIH model can be evoked by over-excitation of the cardiac arm of sympathetic nervous system (SNS), even before mechanisms of enhanced peripheral vasoconstriction and endothelial dysfunction are initiated (Naghshin et al., 2009)....
Source: Frontiers in Physiology - April 23, 2019 Category: Physiology Source Type: research

Exploring blood microbial communities and their influence on human cardiovascular disease
CONCLUSION: Proteobacteria and Actinobacteria were shown to be independent markers of the risk of CVD. This finding is evidence for the new concept of the role played by blood microbiota dysbiosis in CVD. However, the association between blood microbiota and CVD is still inconsistent. Thus, more deep investigations are required in future to fully understand the role of the bacteria community in causing and preventing CVD.PMID:35293034 | DOI:10.1002/jcla.24354
Source: Atherosclerosis - March 16, 2022 Category: Cardiology Authors: Ikram Khan Imran Khan Zhou Jianye Zhang Xiaohua Murad Khan Mian Gul Hilal Mian Adnan Kakakhel Arshad Mehmood An Lizhe Li Zhiqiang Source Type: research

Association between history of attention-deficit/hyperactivity disorder diagnosis and cardiovascular disease in U.S. adults.
Conclusions: In a nationally representative sample of U.S. adults, we found a significant, positive association between a history of ADHD diagnosis and CVD. Further investigation is needed to replicate our findings and determine the underlying mechanisms. (PsycInfo Database Record (c) 2022 APA, all rights reserved)
Source: Health Psychology - July 18, 2022 Category: Psychiatry & Psychology Source Type: research

30 Days to Better Sleep: Snoring and Sleepiness Equals Sleep Apnea
In reviewing the articles in this blog series, you may have become convinced that the only thing that affects sleep is not sleeping as part of insomnia. However, there are many other sleep disorders that can contribute to difficulty sleeping and waking refreshed. One of the major contributors to excessive sleepiness during the day is trouble breathing at night, best characterized by sleep apnea. Sleep apnea occurs when the upper airway collapses during sleep. Tissues in the airway, from the nose past the soft palate to the base of the tongue, may obstruct the flow of air. When this occurs, this obstruction may be partial ...
Source: About Sleep Disorders - January 23, 2013 Category: Sleep Medicine Source Type: news

Effect of Reduced Sympathetic Hyperactivity on Cardiovascular Risk Factors in Kidney Transplantation Patients
Abstract: Background: Hyperactivity of the sympathetic nervous system caused by chronic kidney disease has detrimental effects on hypertension and cardiovascular morbidity. Kidney transplantation does not ameliorate sympathetic nerve overactivity; however, bilateral nephrectomy eliminates it. The aim of the study was to evaluate the effect of bilateral nephrectomy on risk factors for cardiovascular morbidity and mortality in long-term follow-up. Material and Methods: We studied 24 kidney recipients aged 44 ± 13 years who had undergone native bilateral nephrectomy. The control group included 17 recipients with preserve...
Source: Transplantation Proceedings - May 1, 2013 Category: Transplant Surgery Authors: M. Boratyńska, A.M. Zoń, M. Obremska, K. Pocza̧tek, M. Protasiewicz, M. Magott, M. Klinger Tags: Renal Transplantation Source Type: research

Adderall® (Amphetamine-Dextroamphetamine) Toxicity
This article discusses our present understanding of Adderall® intoxication and examines 3 dogs presented to our practice after ingestion of large amounts of the drug.
Source: Topics in Companion Animal Medicine - February 1, 2013 Category: Veterinary Research Authors: Kevin T. Fitzgerald, Alvin C. Bronstein Source Type: research

Effects of unilateral stereotactic posterior striatotomy on harmaline‐induced tremor in rats
Although long known and the most prevalent movement disorder, pathophysiology of essential tremor (ET) remains controversial. The most accepted hypothesis is that it is caused by a dysfunction of the olivocerebellar system. Vilela Filho et al. [2001; Stereotact Funct Neurosurg 77:149–150], however, reported a patient with unilateral hand ET that was completely relieved after a stroke restricted to the contralateral posterior putamen and suggested that ET could be the clinical manifestation of posterior putamen hyperactivity. The present study was designed to evaluate this hypothesis in the most often used model of ET, ha...
Source: Journal of Neuroscience Research - July 19, 2013 Category: Neuroscience Authors: Osvaldo Vilela‐Filho, Fernando P. Ferraz, Breno A. Barros, Luciana O. Silva, Suzana F. Anunciação, Joaquim T. Souza, Delson J. Silva, Mauricio B. Leite, Ingrid B. Atayde, Paulo C. Ragazzo, Paula G. Barreto, Mariana A. Nobrega, Maisa R. Araujo, Mayra R Tags: Research Article Source Type: research

Adderall® (Amphetamine-Dextroamphetamine) Toxicity
This article discusses our present understanding of Adderall® intoxication and examines 3 dogs presented to our practice after ingestion of large amounts of the drug.
Source: Topics in Companion Animal Medicine - February 1, 2013 Category: Veterinary Research Authors: Kevin T. Fitzgerald, Alvin C. Bronstein Source Type: research

Abstract 241: Splenic T Regulatory Lymphocytes Are Reduced in Genetically Hypertensive Rats Associated with Central Sympathoexcitation Poster Session I
Conclusion: Our findings indicate that splenic Tregs are reduced in SHRSP at both prehypertensive and established hypertensive stages. These alterations may contribute to the development and maintenance of hypertension. Central sympathoinhibition increases the reduced splenic Tregs in SHRSP suggesting interaction between sympathetic hyperactivity and Tregs.
Source: Hypertension - October 30, 2013 Category: Cardiology Authors: Katsuki, M., Hirooka, Y., Kishi, T., Sunagawa, K. Tags: Poster Session I Source Type: research

Cardiovascular risks and management during Attention Deficit Hyperactivity Disorder treatment with methylphenidate.
Abstract Attention Deficit Hyperactivity Disorder (ADHD) is one of the most common of the pediatric neuropsychiatric disorders. Methylphenidate is an important element of therapeutic strategies for ADHD. Clinicians are interested in the safety of methylphenidate. Because this drug raises heart rate and blood pressure, concerns have been raised about its cardiovascular safety. Concerns were based on case reports of sudden cardiac death in methylphenidate users, plausible pharmacological pathways involving well-established stimulant effects on heart rate and blood pressure. Until recently, data were limited to a num...
Source: Archives de Pediatrie - December 2, 2013 Category: Pediatrics Authors: Bange F, Le Heuzey MF, Acquaviva E, Delorme R, Mouren MC Tags: Arch Pediatr Source Type: research