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Cancer: Prostate Cancer

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Total 76 results found since Jan 2013.

Erectile Dysfunction in Individuals with Neurologic Disability: A Hospital-based, Cross-sectional Study
Conclusion: The occurence of erectile dysfunction is significantly more prevalent among neurologically disabled men, particularly those with lesions below S2–S4, than among men without neurologic disability. Considering the prevalence of erectile dysfunction among neurologically disabled men, sexual functioning should be regularly evaluated during acute and long-term rehabilitation, and any existing sexual dysfunction should be addressed in the treatment plan. Introduction Penile erection is a neurovascular event characterized by the dilation of arteries that cause the corpora cavernosa and corpora spongiosum of the peni...
Source: Innovations in Clinical Neuroscience - February 1, 2016 Category: Neuroscience Authors: ICN Online Editor Tags: Current Issue Medical Issues Neurologic Systems and Symptoms Neurology Neuromuscular Disease Original Research Neurogenic SD; Erectile Dysfunction; sexual health; Quality of life Source Type: research

Emerging trends in non-communicable disease mortality in South Africa, 1997 - 2010.
CONCLUSIONS: NCDs contribute to premature mortality in SA, threatening socioeconomic development. While NCD mortality rates have decreased slightly, it is necessary to strengthen prevention and healthcare provision and monitor emerging trends in cause-specific mortality to inform these strategies if the target of 2% annual decline is to be achieved. PMID: 27138667 [PubMed - as supplied by publisher]
Source: South African Medical Journal - May 5, 2016 Category: African Health Tags: S Afr Med J Source Type: research

Canagliflozin Inhibits Human Endothelial Cell Proliferation and Tube Formation
In conclusion, the present study identified canagliflozin as a potent inhibitor of human EC proliferation. The anti-proliferative action of canagliflozin is observed in ECs isolated from both the venous and arterial circulation, and is partly due to the blockade of cyclin A expression. In addition, this study found that canagliflozin inhibits tube formation in cultured ECs and mouse aortic rings. Notably, these actions are specific for canagliflozin and not seen with other SGLT2 inhibitors. The ability of canagliflozin to exert these pleiotropic effects on EC function may contribute to both the adverse and salutary actions...
Source: Frontiers in Pharmacology - April 15, 2019 Category: Drugs & Pharmacology Source Type: research

Dairy foods and health: an umbrella review of observational studies.
In conclusions, dairy may be part of a healthy diet; however, additional studies exploring confounding factors are needed to ascertain the potential detrimental effects. PMID: 31199182 [PubMed - as supplied by publisher]
Source: International Journal of Food Sciences and Nutrition - June 16, 2019 Category: Nutrition Tags: Int J Food Sci Nutr Source Type: research

Impact of Comorbidities on Lung Cancer Screening Evaluation
CONCLUSION: Patient and procedure-level factors may alter the benefits of lung cancer screening. Data concerning individual risk factors and high-risk complications should therefore be incorporated into diagnostic algorithms to optimize clinical benefit and minimize harm. Further study and validation of the risk factors identified herein are warranted.PMID:35641376 | DOI:10.1016/j.cllc.2022.03.012
Source: Clinical Prostate Cancer - May 31, 2022 Category: Cancer & Oncology Authors: Eric M Robinson Benjamin Y Liu Keith Sigel Chung Yin Juan Wisnivesky Minal S Kale Source Type: research

Cheese consumption and multiple health outcomes: an umbrella review and updated meta-analysis of prospective studies
Adv Nutr. 2023 Jun 14:S2161-8313(23)01328-5. doi: 10.1016/j.advnut.2023.06.007. Online ahead of print.ABSTRACTThis umbrella review aims to provide a systematic and comprehensive overview of current evidence from prospective studies on the diverse health effects of cheese consumption. We searched PubMed, Embase, and Cochrane Library to identify meta-analyses/pooled analyses of prospective studies examining the associations between cheese consumption and major health outcomes from inception to August 31, 2022. We reanalyzed and updated previous meta-analyses and performed de novo meta-analyses with recently published prospec...
Source: Adv Data - June 16, 2023 Category: Epidemiology Authors: Mingjie Zhang Xiaocong Dong Zihui Huang Xue Li Yue Zhao Yingyao Wang Huilian Zhu Aiping Fang Edward L Giovannucci Source Type: research

Could Antibodies or Hormones Slow Brain Damage from Alzheimer’s?
Scientists have discovered that certain antibodies may help slow the progression of Alzheimer’s disease. Dr. Patricia Salinas of University College London, UK, and her team focused on a protein called Dkk1, present in raised levels in the brains of people with Alzheimer’s disease. Using brain samples from mice, the team looked at the progressive disintegration of synapses in the hippocampus when exposed to a protein called amyloid-beta, thought to be central to the development of Alzheimer’s disease. “Synaptic loss mediated by amyloid-beta in early stages of the disease might contribute to cognitive...
Source: Psych Central - June 1, 2013 Category: Psychiatry Authors: Jane Collingwood Tags: Aging Alzheimer's Disorders General Seniors Abnormal Deposits Alzheimer S Disease Antibodies Brain Area Brain Damage Cognitive Decline Cognitive Impairments Disintegration Dr Patricia Dr Simon Hippocampus Journal Of Neurosc Source Type: news

Plasma testosterone, obesity, metabolic syndrome and diabetes.
Abstract The frequency of diabetes and/or metabolic syndrome rises concurrently with that of body mass index (BMI). In adult men, plasma testosterone level changes evolve inversely to that of BMI. Plasma total testosterone, sex hormone-binding globulin (SHBG) and free testosterone are significantly lower in adult men with a clinical and biological pattern of metabolic syndrome (MetS) than in those without such a pattern. After adjustment for confounding factors, diabetes type 2 (DT2) remains associated with a significant decrease of plasma testosterone level. The androgenic blockade, used as a treatment for dissem...
Source: Presse Medicale - November 21, 2013 Category: Journals (General) Authors: Prévost G, Eas F, Kuhn JM Tags: Presse Med Source Type: research

Adiponectin as a routine clinical biomarker.
Abstract Adiponectin is a protein synthesized and secreted predominantly by adipocytes into the peripheral blood. However, circulating adiponectin level is inversely related with body weight, especially visceral fat accumulation. The mechanism of this paradoxical relation remains obscure. Low circulating adiponectin concentrations (hypoadiponectinemia; <4 μg/mL) are associated with a variety of diseases, including dysmetabolism (type 2 diabetes, insulin resistance, hypertension, dyslipidemia, metabolic syndrome, hyperuricemia), atherosclerosis (coronary artery disease, stroke, peripheral artery disease), slee...
Source: Clin Med Res - January 1, 2014 Category: Research Authors: Kishida K, Funahashi T, Shimomura I Tags: Best Pract Res Clin Endocrinol Metab Source Type: research

Fruits And Vegetables May Not Prevent Cancer
BOSTON (CBS) – Who hasn’t heard that eating a lot of fruits and vegetables can help you fend off cancer? Dr. Walter Willett, a leading expert on nutrition and health at the Harvard School of Public Health, says your diet may play less of a role in cancer prevention as originally thought. “As better data have come along,” he says, “the benefits for cancer don’t look nearly as impressive.” And fat doesn’t appear to be as bad as once thought for promoting cancer either. “There had been a strong belief that fat in our diet was the major cause of breast cancer, colon cancer, prostate cancer and oth...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - June 5, 2014 Category: Consumer Health News Authors: deanreddington Tags: Health Local News Seen On WBZ-TV Syndicated Local Watch Listen Cancer Dr. Mallika Marshall Dr. Walter Willett Fruit Vegetables Source Type: news

Risk of New‐onset Diabetes after Androgen Deprivation Therapy for Prostate Cancer in the Asian Population
ConclusionsThere was increased risk of new‐onset DM after ADT for prostate cancer in the Asian population. Regular screening of DM can be considered after the initiation of ADT, especially in patients with known history of dyslipidemia and impaired fasting glucose.
Source: Journal of Diabetes - September 1, 2014 Category: Endocrinology Authors: Jeremy Yuen Chun Teoh, Peter Ka Fung Chiu, Samson Yun Sang Chan, Darren Ming Chun Poon, Ho‐Yuen Cheung, Simon See Ming Hou, Chi‐Fai Ng Tags: Original Article Source Type: research

Risk of Acute Myocardial Infarction after Androgen Deprivation Therapy for Prostate Cancer in the Chinese Population
Conclusions‐ There was increased risk of AMI after ADT for prostate cancer in the Chinese population.‐ Hyperlipidemia and poor ECOG performance status were also significant risk factors for developing AMI.‐ The risk of AMI should be considered while deciding on ADT, especially in patients with history of hyperlipidemia and relatively poor ECOG performance status.Prostate cancer, androgen deprivation therapy, myocardial infarction, Asian population
Source: BJU International - October 18, 2014 Category: Urology & Nephrology Authors: Jeremy Yuen Chun Teoh, Samson Yun Sang Chan, Peter Ka Fung Chiu, Darren Ming Chun Poon, Ho Yuen Cheung, Simon See Ming Hou, Chi‐Fai Ng Tags: Urological Oncology Source Type: research

Androgen deprivation therapy and cardiovascular risk in chinese patients with nonmetastatic carcinoma of prostate.
Conclusion. ADT in Chinese patients with nonmetastatic prostate cancer with no previously documented cardiovascular disease was associated with subsequent development of cardiovascular events. PMID: 24803931 [PubMed]
Source: Journal of Oncology - November 17, 2014 Category: Cancer & Oncology Tags: J Oncol Source Type: research

Abstract A12: Cancer communication in African American churches
Conclusion: Cancer was a frequent topic for disease-focused messages in African-American churches. In addition, three of the five most frequent disease topics matched the leading causes of death in the African-American community. The match was not as close in regards to leading causes of cancer death. Breast and prostate cancer information was frequently found; however, despite the high rates of mortality associated with lung cancer, colorectal cancer, and leukemia/lymphoma, information on these cancers was present much less frequently. No pancreatic cancer messages were found. Disease related information was seen that inc...
Source: Cancer Epidemiology Biomarkers and Prevention - November 13, 2014 Category: Cancer & Oncology Authors: Harmon, B. E., Chastain, E., Chock, M., Wirth, M., Hebert, J. R. Tags: Cancer Communications: Poster Presentations - Proffered Abstracts Source Type: research