Cross-Sectional Study of Soil-Transmitted Helminthiases in Black Belt Region of Alabama, USA
Emerg Infect Dis. 2023 Dec;29(12):2461-2470. doi: 10.3201/eid2912.230751.ABSTRACTWe conducted a cross-sectional study to determine the prevalence of soil-transmitted helminthiases (STH) in areas of rural Alabama, USA, that have sanitation deficits. We enrolled 777 children; 704 submitted stool specimens and 227 a dried blood spot sample. We microscopically examined stool specimens from all 704 children by using Mini-FLOTAC for helminth eggs. We tested a subset by using molecular techniques: real-time PCR analysis for 5 STH species, TaqMan Array Cards for enteric helminths, and digital PCR for Necator americanus hookworm. W...
Source: Emerging Infectious Diseases - November 21, 2023 Category: Infectious Diseases Authors: Claudette Poole Troy Barker Richard Bradbury Drew Capone Amy Hutson Chatham Sukwan Handali Eduardo Rodriguez Yvonne Qvarnstrom Joe Brown Source Type: research
Cross-Sectional Study of Soil-Transmitted Helminthiases in Black Belt Region of Alabama, USA
Emerg Infect Dis. 2023 Dec;29(12):2461-2470. doi: 10.3201/eid2912.230751.ABSTRACTWe conducted a cross-sectional study to determine the prevalence of soil-transmitted helminthiases (STH) in areas of rural Alabama, USA, that have sanitation deficits. We enrolled 777 children; 704 submitted stool specimens and 227 a dried blood spot sample. We microscopically examined stool specimens from all 704 children by using Mini-FLOTAC for helminth eggs. We tested a subset by using molecular techniques: real-time PCR analysis for 5 STH species, TaqMan Array Cards for enteric helminths, and digital PCR for Necator americanus hookworm. W...
Source: Emerging Infectious Diseases - November 21, 2023 Category: Infectious Diseases Authors: Claudette Poole Troy Barker Richard Bradbury Drew Capone Amy Hutson Chatham Sukwan Handali Eduardo Rodriguez Yvonne Qvarnstrom Joe Brown Source Type: research
Micro (nano) plastics uptake, toxicity and detoxification in plants: Challenges and prospects
Ecotoxicol Environ Saf. 2023 Nov 16;268:115676. doi: 10.1016/j.ecoenv.2023.115676. Online ahead of print.ABSTRACTPlastic pollution has emerged as a global challenge affecting ecosystem health and biodiversity conservation. Terrestrial environments exhibit significantly higher plastic concentrations compared to aquatic systems. Micro/nano plastics (MNPs) have the potential to disrupt soil biology, alter soil properties, and influence soil-borne pathogens and roundworms. However, limited research has explored the presence and impact of MNPs on aquaculture systems. MNPs have been found to inhibit plant and seedling growth and...
Source: Ecotoxicology and Environmental Safety - November 18, 2023 Category: Environmental Health Authors: Zahra Dehghanian Behnam Asgari Lajayer Zahra Biglari Quchan Atigh Shahnoush Nayeri Mohammad Ahmadabadi Leila Taghipour Venkatramanan Senapathi Tess Astatkie G W Price Source Type: research
Micro (nano) plastics uptake, toxicity and detoxification in plants: Challenges and prospects
Ecotoxicol Environ Saf. 2023 Nov 16;268:115676. doi: 10.1016/j.ecoenv.2023.115676. Online ahead of print.ABSTRACTPlastic pollution has emerged as a global challenge affecting ecosystem health and biodiversity conservation. Terrestrial environments exhibit significantly higher plastic concentrations compared to aquatic systems. Micro/nano plastics (MNPs) have the potential to disrupt soil biology, alter soil properties, and influence soil-borne pathogens and roundworms. However, limited research has explored the presence and impact of MNPs on aquaculture systems. MNPs have been found to inhibit plant and seedling growth and...
Source: Ecotoxicology and Environmental Safety - November 18, 2023 Category: Environmental Health Authors: Zahra Dehghanian Behnam Asgari Lajayer Zahra Biglari Quchan Atigh Shahnoush Nayeri Mohammad Ahmadabadi Leila Taghipour Venkatramanan Senapathi Tess Astatkie G W Price Source Type: research
Spread of the Zoonotic Nematode Baylisascaris procyonis into a Naive Raccoon Population
We present evidence for the roundworm spreading into a naive raccoon population through natural dispersal of infected raccoons. We sampled 181 raccoons from Saxony-Anhalt, a German federal state containing contact zones of different raccoon populations, two of which were previously free of the parasite. We screened the raccoons for roundworms and used microsatellite-based assignment tests to determine the genetic origin of the raccoons and their parasites. We detected roundworms in 16 of 45 raccoons sampled in a previously roundworm-free area in the northern part of the state. The largest proportion of the genetic ancestry...
Source: EcoHealth - November 16, 2023 Category: Environmental Health Source Type: research
An unusual finding: Biliary ascariasis in a pregnant patient managed conservatively-a case report
CONCLUSION: This case report emphasizes the importance of considering biliary ascariasis in pregnant patients with biliary symptoms. Timely diagnosis, utilizing imaging modalities, and initiating conservative management with anti-helminthic therapy can lead to successful treatment outcomes. Increased awareness and understanding of this condition can aid clinicians in providing optimal care to similar patients.PMID:37811107 | PMC:PMC10553149 | DOI:10.1097/MS9.0000000000001205 (Source: Annals of Medicine)
Source: Annals of Medicine - October 9, 2023 Category: Internal Medicine Authors: Shailendra Katwal Rabindra Oli Amrit Bhusal Sushmita Bhandari Astha Ghimire Roshani Lama Source Type: research
Antiparasitic activity of ivermectin: Four decades of research into a "wonder drug"
Eur J Med Chem. 2023 Sep 27;261:115838. doi: 10.1016/j.ejmech.2023.115838. Online ahead of print.ABSTRACTParasitic diseases still pose a serious threat to human and animal health, particularly for millions of people and their livelihoods in low-income countries. Therefore, research into the development of effective antiparasitic drugs remains a priority. Ivermectin, a sixteen-membered macrocyclic lactone, exhibits a broad spectrum of antiparasitic activities, which, combined with its low toxicity, has allowed the drug to be widely used in the treatment of parasitic diseases affecting humans and animals. In addition to its ...
Source: European Journal of Medicinal Chemistry - October 4, 2023 Category: Chemistry Authors: Micha ł Sulik Micha ł Antoszczak Adam Huczy ński Dietmar Steverding Source Type: research
Antiparasitic activity of ivermectin: Four decades of research into a "wonder drug"
Eur J Med Chem. 2023 Sep 27;261:115838. doi: 10.1016/j.ejmech.2023.115838. Online ahead of print.ABSTRACTParasitic diseases still pose a serious threat to human and animal health, particularly for millions of people and their livelihoods in low-income countries. Therefore, research into the development of effective antiparasitic drugs remains a priority. Ivermectin, a sixteen-membered macrocyclic lactone, exhibits a broad spectrum of antiparasitic activities, which, combined with its low toxicity, has allowed the drug to be widely used in the treatment of parasitic diseases affecting humans and animals. In addition to its ...
Source: European Journal of Medicinal Chemistry - October 4, 2023 Category: Chemistry Authors: Micha ł Sulik Micha ł Antoszczak Adam Huczy ński Dietmar Steverding Source Type: research
Prevalence and intensity of soil-transmitted helminth infections in Uganda: Results from population-based prevalence surveys in five districts
by Benjamin Tinkitina, Prudence Beinamaryo, Moses Adriko, Betty Nabatte, Moses Arinaitwe, Alfred Mubangizi, Paul Emerson, Sanjaya Dhakal, Kristin M. Sullivan
BackgroundSoil-transmitted helminth (STH) infections are caused by roundworms (Ascaris lumbricoides), whipworms (Trichuris trichiura), and hookworms (Necator americanus andAncylostoma duodenale). In Uganda, baseline surveys conducted during the late 1990s and early 2000s suggested STH infections were common, with prevalence>50% among surveyed schoolchildren. In 2003, a national program was launched with mass preventative chemotherapy (PC) and health education for chil...
Source: PLoS Neglected Tropical Diseases - September 26, 2023 Category: Tropical Medicine Authors: Benjamin Tinkitina Source Type: research
Implementation and Outcomes of an Empiric Ivermectin Strongyloides Treatment Protocol for Patients Receiving High-Dose Corticosteroids for Severe COVID-19
Am J Trop Med Hyg. 2023 Jul 17;109(3):650-655. doi: 10.4269/ajtmh.23-0121. Print 2023 Sep 6.ABSTRACTStrongyloides stercoralis is a parasitic roundworm that is present worldwide and can cause lifelong, often asymptomatic, infection. Immunosuppression, particularly by corticosteroids, is a risk factor for hyperinfection syndrome and disseminated strongyloidiasis-severe disease states that can lead to septic shock and death. Our institution implemented a strongyloidiasis screening and empiric ivermectin treatment protocol for inpatients receiving high-dose corticosteroids for severe COVID-19. Among 487 COVID-19 admissions tre...
Source: The American Journal of Tropical Medicine and Hygiene - September 7, 2023 Category: Tropical Medicine Authors: Benjamin Swart Aileen Ahiskali Jack M Wolf Megan Shaughnessy Source Type: research
Implementation and Outcomes of an Empiric Ivermectin Strongyloides Treatment Protocol for Patients Receiving High-Dose Corticosteroids for Severe COVID-19
Am J Trop Med Hyg. 2023 Jul 17;109(3):650-655. doi: 10.4269/ajtmh.23-0121. Print 2023 Sep 6.ABSTRACTStrongyloides stercoralis is a parasitic roundworm that is present worldwide and can cause lifelong, often asymptomatic, infection. Immunosuppression, particularly by corticosteroids, is a risk factor for hyperinfection syndrome and disseminated strongyloidiasis-severe disease states that can lead to septic shock and death. Our institution implemented a strongyloidiasis screening and empiric ivermectin treatment protocol for inpatients receiving high-dose corticosteroids for severe COVID-19. Among 487 COVID-19 admissions tre...
Source: Am J Trop Med Hyg - September 7, 2023 Category: Infectious Diseases Authors: Benjamin Swart Aileen Ahiskali Jack M Wolf Megan Shaughnessy Source Type: research
Implementation and Outcomes of an Empiric Ivermectin Strongyloides Treatment Protocol for Patients Receiving High-Dose Corticosteroids for Severe COVID-19
Am J Trop Med Hyg. 2023 Jul 17;109(3):650-655. doi: 10.4269/ajtmh.23-0121. Print 2023 Sep 6.ABSTRACTStrongyloides stercoralis is a parasitic roundworm that is present worldwide and can cause lifelong, often asymptomatic, infection. Immunosuppression, particularly by corticosteroids, is a risk factor for hyperinfection syndrome and disseminated strongyloidiasis-severe disease states that can lead to septic shock and death. Our institution implemented a strongyloidiasis screening and empiric ivermectin treatment protocol for inpatients receiving high-dose corticosteroids for severe COVID-19. Among 487 COVID-19 admissions tre...
Source: The American Journal of Tropical Medicine and Hygiene - September 7, 2023 Category: Tropical Medicine Authors: Benjamin Swart Aileen Ahiskali Jack M Wolf Megan Shaughnessy Source Type: research
Implementation and Outcomes of an Empiric Ivermectin Strongyloides Treatment Protocol for Patients Receiving High-Dose Corticosteroids for Severe COVID-19
Am J Trop Med Hyg. 2023 Jul 17;109(3):650-655. doi: 10.4269/ajtmh.23-0121. Print 2023 Sep 6.ABSTRACTStrongyloides stercoralis is a parasitic roundworm that is present worldwide and can cause lifelong, often asymptomatic, infection. Immunosuppression, particularly by corticosteroids, is a risk factor for hyperinfection syndrome and disseminated strongyloidiasis-severe disease states that can lead to septic shock and death. Our institution implemented a strongyloidiasis screening and empiric ivermectin treatment protocol for inpatients receiving high-dose corticosteroids for severe COVID-19. Among 487 COVID-19 admissions tre...
Source: Am J Trop Med Hyg - September 7, 2023 Category: Infectious Diseases Authors: Benjamin Swart Aileen Ahiskali Jack M Wolf Megan Shaughnessy Source Type: research
