Genetic mutations may be linked to infertility, early menopause
(Washington University School of Medicine) A new study from Washington University School of Medicine in St. Louis identifies a specific gene's previously unknown role in fertility. When the gene is missing in fruit flies, roundworms, zebrafish and mice, the animals are infertile or lose their fertility unusually early but appear otherwise healthy. Analyzing genetic data in people, the researchers found an association between mutations in this gene and early menopause. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 31, 2020 Category: International Medicine & Public Health Source Type: news

Helminth infections common in Medieval Europe, grave study finds
(PLOS) Although helminth infections--including tapeworms and roundworms--are among the world's top neglected diseases, they are no longer endemic in Europe. However, researchers reporting in PLOS Neglected Tropical Diseases report that these infections were common in Medieval Europe, according to grave samples analyzed from across the continent. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - August 27, 2020 Category: Infectious Diseases Source Type: news

Tinkering with roundworm proteins offers hope for anti-aging drugs
(The Korea Advanced Institute of Science and Technology (KAIST)) KAIST researchers have been able to dial up and down creatures' lifespans by altering the activity of proteins found in roundworm cells that tell them to convert sugar into energy when their cellular energy is running low. Humans also have these proteins, offering up the intriguing possibilities for developing longevity-promoting drugs. These new findings were published on July 1 in Science Advances. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 31, 2020 Category: International Medicine & Public Health Source Type: news

Mother roundworms have ultra-protective instincts
(University of Iowa) University of Iowa biologists have learned animals can alert future offspring of dangers they will encounter when born. In studies with roundworms and mouse cells, researchers showed how mothers pass chemical signals to their unfertilized eggs, where the warning is stored in the egg cells and passed to offspring after birth. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 18, 2020 Category: International Medicine & Public Health Source Type: news

Molecular switch plays crucial role in learning from negative experiences
(KU Leuven) Neurobiologists at KU Leuven have discovered how the signalling molecule Neuromedin U plays a crucial role in our learning process. The protein allows the brain to recall negative memories and, as such, learn from the past. The findings of their study on roundworms have been published in the journal Nature Communications. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - April 29, 2020 Category: Biology Source Type: news

Brain cells protect muscles from wasting away
(University of California - Berkeley) Several processes in the roundworm C. elegans boost the stress response in cells, incidentally making worms resistant to a high-fat diet and extending their lifespan. UC Berkeley researchers have found another: cells called glia that release a hormone that boosts the unfolded protein response in the endoplasmic reticulum of the worm's cells, effectively doubling lifespan. This could lead to interventions to tune up peripheral cells, such as muscle cells, and prevent age-related deterioration in humans. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 21, 2020 Category: International Medicine & Public Health Source Type: news

Could a probiotic prevent or reverse Parkinson's?
Scientists recently tested probiotics in a roundworm model of Parkinson ’s. A particular bacterium had a protective effect and improved symptoms. (Source: Parkinson's Disease News From Medical News Today)
Source: Parkinson's Disease News From Medical News Today - January 23, 2020 Category: Neurology Tags: Parkinson's Disease Source Type: news

Medical News Today: Could a probiotic prevent or reverse Parkinson's?
Scientists recently tested probiotics in a roundworm model of Parkinson ’s. A particular bacterium had a protective effect and improved symptoms. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - January 23, 2020 Category: Consumer Health News Tags: Parkinson's Disease Source Type: news

Plants found to speak roundworm's language
(Boyce Thompson Institute) Nematodes are tiny, ubiquitous roundworms that infect plant roots, causing more than $100 billion in crop damage worldwide each year. New research has found that plants enter into a 'chemical dialog' with the worms to repel infestations, providing insights into how farmers could fight these pests. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - January 10, 2020 Category: Biology Source Type: news

Medical News Today: Even 'dead,' this probiotic may be effective against inflammation
A new study in roundworms and elderly mice suggests that even the inactivated form of a probiotic bacterium could reduce inflammation and promote health. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - December 10, 2019 Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news

Surprising study finds people who were under 'mild stress' as children live LONGER
A new study from the University of Michigan has found that roundworms that produced more radical molecules early in development lived longer than worms that produced fewer. (Source: the Mail online | Health)
Source: the Mail online | Health - December 4, 2019 Category: Consumer Health News Source Type: news

Public-private partnership launched to develop new drugs for roundworm infections
(Drugs for Neglected Diseases Initiative) Public-private partnership launched to develop new drugs for roundworm infections. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - November 28, 2019 Category: Infectious Diseases Source Type: news

Doctor plucks a 'swimming' parasitic worm from a man's eye
The patient, known only as Mr Yan, 54, from the city of Ningbo, China, was infected with the Thelazia callipaeda roundworm species, which are usually carried by cats and dogs. (Source: the Mail online | Health)
Source: the Mail online | Health - November 25, 2019 Category: Consumer Health News Source Type: news

How One Neuron Regulates Two Separate Behaviors
A major sensory neuron in roundworms distinguishes proprioception from harmful touch by sending out local or whole-cell signals, respectively. (Source: The Scientist)
Source: The Scientist - November 14, 2019 Category: Science Tags: News & Opinion Source Type: news

Medical News Today: New three-sexed roundworm species has 'extreme arsenic resistance'
Scientists have found a new ringworm species that has three sexes and is resistant to 500 times the arsenic concentration that would kill a human. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - October 2, 2019 Category: Consumer Health News Tags: Veterinary Source Type: news

Researchers look at a compound that can extend the lifespan of worms
This study reveals a new life-extension... (Source: NaturalNews.com)
Source: NaturalNews.com - September 18, 2019 Category: Consumer Health News Source Type: news

Gene that controls egg development in worms could one day be 'included in food additives'
A team at the Hebrew University of Jerusalem analysed the DNA of roundworms. Like humans, the animals contain 20,000 genes. They found the gene ogr-2 controls egg maturation. (Source: the Mail online | Health)
Source: the Mail online | Health - September 10, 2019 Category: Consumer Health News Source Type: news

Featured Review: Treating school children with drugs to kill soil - transmitted worms
In 2015 Cochrane published a review on this topic, which has now been updated to include six new trials, additional data from included trials, and addresses comments and criticisms.Global Advocacy organisations claim routine deworming of all school children at regular intervals with deworming drugs in areas where helminth infection is common has substantive health and societal effects beyond the removal of worms.This interview with David Taylor Robinson, Professor of Public Health and Policy, Honorary Consultant in Child Public Health at The University of Liverpool, tells us a little more about this review.What is dewormin...
Source: Cochrane News and Events - September 10, 2019 Category: Information Technology Authors: Katie Abbotts Source Type: news

Oldest Known Parasites Found in Ancient Puma Feces
Researchers isolate roundworm DNA from animal excrement that is about 17,000 years old. (Source: The Scientist)
Source: The Scientist - August 28, 2019 Category: Science Tags: News & Opinion Source Type: news

Oldest parasite DNA yet recorded found in prehistoric puma poo
Coprolite reveals felines in southern Andes had roundworm 17,000 years ago, long before humans got thereThe compact, gnarled and knobbly specimen looks like a root of ginger. In fact, it ’s 17,000-year-old puma poo, and it contains the oldest parasite DNA yet recorded.The team of researchers behind the discovery say the finding not only confirms that the felines were prowling around the Andes towards the end of the last ice age, but reveals that they were infested with roundworm long before humans and their animals turned up.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - August 27, 2019 Category: Science Authors: Nicola Davis Tags: Science Fossils Genetics Argentina Biology Americas World news Source Type: news

World Health Organisation ’s New Effort Can Help End Neglected Tropical Diseases
In the Solomon Islands, approximately 40 percent of the population of 550,000 could have active Trachoma. Credit: Catherine Wilson/IPS.By Ifeanyi NsoforABUJA, Aug 19 2019 (IPS) Recently, the World Health Organisation (WHO) launched global consultations for a new Roadmap on how to eliminate Neglected Tropical Diseases (NTDs). The roadmap would help achieve universal health coverage by 2030, address health emergencies and promote healthier populations. This intervention is unprecedented because it could begin to reverse the neglect and inequities that the 17 main NTDs bring. Many NTDs are debilitating and red...
Source: IPS Inter Press Service - Health - August 19, 2019 Category: International Medicine & Public Health Authors: Ifeanyi Nsofor Tags: Development & Aid Global Headlines Health Source Type: news

Worm pheromones protect major crops
(Boyce Thompson Institute) Protecting crops from pests and pathogens without using toxic pesticides has been a longtime goal of farmers. Researchers at Boyce Thompson Institute have found that compounds from an unlikely source - microscopic soil roundworms - could achieve this aim. As described in research published in Journal of Phytopathology, these compounds helped protect major crops from various pathogens, and thus have potential to save billions of dollars and increase agricultural sustainability around the world. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - July 25, 2019 Category: Biology Source Type: news

Genome research shows that the body controls the integrity of heritable genomes
(University of Cologne) Writing in Developmental Cell, scientists at the University of Cologne presented new findings that challenge established concepts of genetic inheritance. They have proven that somatic cells of the roundworm C. elegans influence heredity. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - July 24, 2019 Category: International Medicine & Public Health Source Type: news

An AI technology to reveal the characteristics of animal behavior only from the trajectory
(Osaka University) Recording the movements of people and animals has become easy because of small GPS devices and video cameras. However, the reasons for such movements remain difficult to infer. Yamazaki and colleagues have developed a flexible artificial intelligence technology to understand the movement of animals, ranging from roundworms in petri dishes to penguins in the Antarctic Ocean. This method may make it easier to understand animal movements as well as their underlying brain activities. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - July 16, 2019 Category: Biology Source Type: news

Stored in Synapses: How Scientists Completed a Map of the Roundworm ’s Brain
Redrawing neural connections led to new clues about sex differences in scientists ’ favorite model organism. (Source: NYT Health)
Source: NYT Health - July 3, 2019 Category: Consumer Health News Authors: Knvul Sheikh Tags: Worms Nerves and Nervous System Brain Biology and Biochemistry Nature (Journal) Einstein, Albert, College of Medicine Scott Emmons your-feed-science Source Type: news

First Complete Wiring Diagram of an Animal's Nervous System
July 3, 2019—(BRONX, NY)—In a study published online today in Nature, researchers at Albert Einstein College of Medicine describe the first complete wiring diagram of the nervous system of an animal, the roundworm Caenorhabditis elegans, used by scientists worldwide as a model organism. The study includes adults of both sexes and reveals substantial differences between them. (Source: Einstein News)
Source: Einstein News - July 3, 2019 Category: Universities & Medical Training Source Type: news

First Complete Wiring Diagram of an Animal's Nervous System
July 3, 2019—(BRONX, NY)—In a study published online today inNature, researchers at Albert Einstein College of Medicine describe the first complete wiring diagram of the nervous system of an animal, the roundworm Caenorhabditis elegans, used by scientists worldwide as a model organism. The study includes adults of both sexes and reveals substantial differences between them. (Source: Einstein News)
Source: Einstein News - July 3, 2019 Category: Universities & Medical Training Source Type: news

Perfect timing: Making the 'switch' from juvenile to adult
(University of Rochester Medical Center) Very little is known about how the onset of puberty is controlled in humans, but the discovery of a new gene in the roundworm C. elegans could be the 'missing link' that determines when it's time to make this juvenile-to-adult transition. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 3, 2019 Category: International Medicine & Public Health Source Type: news

Gruesome footage shows a 1ft WORM being pulled from a woman's bowels
The woman, known only as Ms Yang, 41, had been battling abdominal pain for a decade. After multiple trips to hospital, doctors in East China's Zhejiang Province discovered the roundworm on June 14. (Source: the Mail online | Health)
Source: the Mail online | Health - June 18, 2019 Category: Consumer Health News Source Type: news

Long-lived roundworms helped identify new anti-aging compounds among FDA approved drugs
(Gero) Researchers from Gero, Skolkovo Institute of Science and Technology (Skoltech), Moscow Institute of Physics and Technology (MIPT), and University of Arkansas for Medical Sciences (UAMS) collaborated to derive a transcriptomic signature of aging, which they confirmed using large transcriptomic databases. They discovered that aging in nematodes is partially programmed and can be therapeutically reversed by a number of FDA-approved drugs. The study is published in Scientific Reports. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - May 22, 2019 Category: International Medicine & Public Health Source Type: news

Long-lived roundworms help identify new anti-aging compounds among the FDA approved drugs
(Moscow Institute of Physics and Technology) Researchers from Gero, Skolkovo Institute of Science and Technology (Skoltech), Moscow Institute of Physics and Technology (MIPT), and University of Arkansas for Medical Sciences (UAMS) collaborated to derive a transcriptomic signature of aging, which they confirmed using large transcriptomic databases. They discovered that aging in nematodes is partially programmed and can be therapeutically reversed by a number of FDA-approved drugs. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - May 22, 2019 Category: International Medicine & Public Health Source Type: news

C. elegans roundworms 'harvest' an essential coenzyme from the bacteria they consume
(Massachusetts General Hospital) A study conducted in C.elegans nematode roundworms may lead to improved treatment of a rare human genetic disorder that causes severe neurological symptoms leading to death in early childhood. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 26, 2019 Category: International Medicine & Public Health Source Type: news

Discovery of life-extension pathway in worms demonstrates new way to study aging
(Scripps Research Institute) An enzyme-blocking molecule can extend the lifespan of Caenorhabditis elegans roundworms by as much as 45 percent, largely by modulating a cannabinoid biological pathway, according to a study from scientists at Scripps Research. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - March 25, 2019 Category: International Medicine & Public Health Source Type: news

Experiments with roundworms suggest alternatives for the treatment of schizophrenia
(Funda ç ã o de Amparo à Pesquisa do Estado de S ã o Paulo) Researchers used C. elegans as an animal model to investigate the importance of certain human genes for the treatment of schizophrenia. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 19, 2019 Category: International Medicine & Public Health Source Type: news

Rice U. study highlights danger of vitamin B12 deficiency
(Rice University) Using roundworms, one of Earth's simplest animals, Rice University bioscientists have found the first direct link between a diet containing too little vitamin B12 and an increased risk of infection by two potentially deadly pathogens. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - March 13, 2019 Category: Cancer & Oncology Source Type: news

Long-lived parents produce better quality offspring
(University of East Anglia) New research shows that long-lived parents produce better quality offspring.Researchers studied a gene associated with ageing in roundworms. They found that by reducing this gene's expression, they could not only more than double the worm's lifespan - but also improve the fitness of its offspring.The findings support an emerging new theory that we have genes that age us, and that shutting down these genes in later life could one day help us stay younger and healthier for longer. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - March 4, 2019 Category: International Medicine & Public Health Source Type: news

Inside the brains of hungry worms, researchers find clues about how they hunt
(Rockefeller University) When looking for food, the roundworm C. elegans searches the same area for up to 20 minutes before trying its luck at more distant locales. New research on the worm's brain explains how this behavior arises at the level of molecules and cells. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 26, 2019 Category: International Medicine & Public Health Source Type: news

The smell of food controls cellular recycling and affects life expectancy
(University of Cologne) The smell of food affects physiology and aging. That is the result of research conducted on the model organism of the roundworm by a research team led by Professor Thorsten Hoppe at the Cluster of Excellence for Aging Research (CECAD). Surprisingly, this relationship is due to a single pair of olfactory neurons. The results have now been published in Nature Metabolism. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 20, 2019 Category: International Medicine & Public Health Source Type: news

University of Konstanz develops first genetic switch for C. elegans
(University of Konstanz) With their first ever RNA-based inducible system for switching on genes in the roundworm Caenorhabditis elegans, two researchers from the University of Konstanz have closed a significant gap in the research on and usage of genetic switches. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 30, 2019 Category: International Medicine & Public Health Source Type: news

New findings on genes that drive male-female brain differences, timing of puberty
(Columbia University) Columbia University researchers have discovered a group of genes in roundworms that control the onset of puberty and induce sex differences in neural structures that raise new questions of whether differences in male and female behavior are hardwired in our brains. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 2, 2019 Category: International Medicine & Public Health Source Type: news

Antibiotic could protect against neurodegenerative diseases during aging
(eLife) An antibiotic, minocycline, can increase the lifespan of roundworms by preventing the build-up of proteins during aging, a study in the open-access journal eLife reports. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 28, 2018 Category: International Medicine & Public Health Source Type: news

Study documents paternal transmission of epigenetic memory via sperm
(University of California - Santa Cruz) Studies of human populations and animal models suggest that a father's experiences such as diet or environmental stress can influence the health and development of his descendants. How these effects are transmitted across generations, however, remains mysterious. A new study in the roundworm C. elegans documents the transmission via sperm of epigenetic marks that are both necessary and sufficient to guide proper development of germ cells in the offspring. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - October 17, 2018 Category: Biology Source Type: news

Teen Youngest Person in History of IDWeek to Present Teen Youngest Person in History of IDWeek to Present
The 13-year-old scientist turned heads at the conference with a newsworthy abstract that examines levels of roundworm contamination in public parks.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 7, 2018 Category: Consumer Health News Tags: Infectious Diseases News Source Type: news

In a tiny worm, a close-up view of where genes are working
(Princeton University, Engineering School) A team at Princeton's Lewis-Sigler Institute for Integrative Genomics has produced new resources for research involving the roundworm C. elegans: a comprehensive view of which genes are active in each of the four major tissues of adult worms, as well as a tool for predicting gene activity across 76 more specific cell types. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - September 18, 2018 Category: Biology Source Type: news

Man almost goes blind after he was infected with roundworm parasite from eating raw chicken sushi
A Japanese man who ate uncooked chicken sashimi went to hospital with chest pain, where doctors diagnosed him with a parasitic illness which had caused growths to appear in his lungs and liver. (Source: the Mail online | Health)
Source: the Mail online | Health - August 23, 2018 Category: Consumer Health News Source Type: news

Signaling cascade that repairs damaged nerve cells characterized
(Nagoya University) Through a study of roundworm nerve cells with severed axons, researchers at Nagoya University showed that a signaling cascade that normally functions in promoting the phagocytosis of apoptotic cells also acts in inducing axon regeneration. The findings shed light on a fundamental feature of nerve repair, which is limited in the central nervous system in humans, and thus could pave the way towards treatments for brain and spinal cord injuries. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 23, 2018 Category: International Medicine & Public Health Source Type: news

Researchers look to worms for a new model of a peripheral nervous system disease
(Scripps Research Institute) Scientists have discovered that a microscopic roundworm develops similar nerve damage to human patients when their muscle cells are genetically engineered to produce TTR proteins. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 7, 2018 Category: International Medicine & Public Health Source Type: news

Mosquito screening useful in monitoring lymphatic filariasis re-emergence
(PLOS) To ensure elimination of the Wuchereria bancrofti, a parasitic roundworm that causes lymphatic filariasis, public health workers must follow up mass drug administration with careful monitoring for recurrence. To that end, a study published this week in PLOS Neglected Tropical Diseases analyzes the effectiveness of mosquito screening as a tool to gauge parasite presence. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - July 26, 2018 Category: Infectious Diseases Source Type: news

Nitric oxide tells roundworms to avoid bad bacteria
(eLife) Nitric oxide gas produced by a type of harmful bacteria lets roundworms know to stay away from it, says a new study published in eLife. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 17, 2018 Category: International Medicine & Public Health Source Type: news