Implementation and Outcomes of an Empiric Ivermectin Strongyloides Treatment Protocol for Patients Receiving High-Dose Corticosteroids for Severe COVID-19
Am J Trop Med Hyg. 2023 Jul 17;109(3):650-655. doi: 10.4269/ajtmh.23-0121. Print 2023 Sep 6.ABSTRACTStrongyloides stercoralis is a parasitic roundworm that is present worldwide and can cause lifelong, often asymptomatic, infection. Immunosuppression, particularly by corticosteroids, is a risk factor for hyperinfection syndrome and disseminated strongyloidiasis-severe disease states that can lead to septic shock and death. Our institution implemented a strongyloidiasis screening and empiric ivermectin treatment protocol for inpatients receiving high-dose corticosteroids for severe COVID-19. Among 487 COVID-19 admissions tre...
Source: Am J Trop Med Hyg - September 7, 2023 Category: Infectious Diseases Authors: Benjamin Swart Aileen Ahiskali Jack M Wolf Megan Shaughnessy Source Type: research
Implementation and Outcomes of an Empiric Ivermectin Strongyloides Treatment Protocol for Patients Receiving High-Dose Corticosteroids for Severe COVID-19
Am J Trop Med Hyg. 2023 Jul 17;109(3):650-655. doi: 10.4269/ajtmh.23-0121. Print 2023 Sep 6.ABSTRACTStrongyloides stercoralis is a parasitic roundworm that is present worldwide and can cause lifelong, often asymptomatic, infection. Immunosuppression, particularly by corticosteroids, is a risk factor for hyperinfection syndrome and disseminated strongyloidiasis-severe disease states that can lead to septic shock and death. Our institution implemented a strongyloidiasis screening and empiric ivermectin treatment protocol for inpatients receiving high-dose corticosteroids for severe COVID-19. Among 487 COVID-19 admissions tre...
Source: The American Journal of Tropical Medicine and Hygiene - September 7, 2023 Category: Tropical Medicine Authors: Benjamin Swart Aileen Ahiskali Jack M Wolf Megan Shaughnessy Source Type: research
Implementation and Outcomes of an Empiric Ivermectin Strongyloides Treatment Protocol for Patients Receiving High-Dose Corticosteroids for Severe COVID-19
Am J Trop Med Hyg. 2023 Jul 17;109(3):650-655. doi: 10.4269/ajtmh.23-0121. Print 2023 Sep 6.ABSTRACTStrongyloides stercoralis is a parasitic roundworm that is present worldwide and can cause lifelong, often asymptomatic, infection. Immunosuppression, particularly by corticosteroids, is a risk factor for hyperinfection syndrome and disseminated strongyloidiasis-severe disease states that can lead to septic shock and death. Our institution implemented a strongyloidiasis screening and empiric ivermectin treatment protocol for inpatients receiving high-dose corticosteroids for severe COVID-19. Among 487 COVID-19 admissions tre...
Source: Am J Trop Med Hyg - September 7, 2023 Category: Infectious Diseases Authors: Benjamin Swart Aileen Ahiskali Jack M Wolf Megan Shaughnessy Source Type: research
Implementation and Outcomes of an Empiric Ivermectin Strongyloides Treatment Protocol for Patients Receiving High-Dose Corticosteroids for Severe COVID-19
Am J Trop Med Hyg. 2023 Jul 17;109(3):650-655. doi: 10.4269/ajtmh.23-0121. Print 2023 Sep 6.ABSTRACTStrongyloides stercoralis is a parasitic roundworm that is present worldwide and can cause lifelong, often asymptomatic, infection. Immunosuppression, particularly by corticosteroids, is a risk factor for hyperinfection syndrome and disseminated strongyloidiasis-severe disease states that can lead to septic shock and death. Our institution implemented a strongyloidiasis screening and empiric ivermectin treatment protocol for inpatients receiving high-dose corticosteroids for severe COVID-19. Among 487 COVID-19 admissions tre...
Source: The American Journal of Tropical Medicine and Hygiene - September 7, 2023 Category: Tropical Medicine Authors: Benjamin Swart Aileen Ahiskali Jack M Wolf Megan Shaughnessy Source Type: research
Implementation and Outcomes of an Empiric Ivermectin Strongyloides Treatment Protocol for Patients Receiving High-Dose Corticosteroids for Severe COVID-19
Am J Trop Med Hyg. 2023 Jul 17;109(3):650-655. doi: 10.4269/ajtmh.23-0121. Print 2023 Sep 6.ABSTRACTStrongyloides stercoralis is a parasitic roundworm that is present worldwide and can cause lifelong, often asymptomatic, infection. Immunosuppression, particularly by corticosteroids, is a risk factor for hyperinfection syndrome and disseminated strongyloidiasis-severe disease states that can lead to septic shock and death. Our institution implemented a strongyloidiasis screening and empiric ivermectin treatment protocol for inpatients receiving high-dose corticosteroids for severe COVID-19. Among 487 COVID-19 admissions tre...
Source: Am J Trop Med Hyg - September 7, 2023 Category: Infectious Diseases Authors: Benjamin Swart Aileen Ahiskali Jack M Wolf Megan Shaughnessy Source Type: research
eIF4E as a molecular wildcard in metazoans RNA metabolism
Biol Rev Camb Philos Soc. 2023 Aug 8. doi: 10.1111/brv.13005. Online ahead of print.ABSTRACTThe evolutionary origin of eukaryotes spurred the transition from prokaryotic-like translation to a more sophisticated, eukaryotic translation. During this process, successive gene duplication of a single, primordial eIF4E gene encoding the mRNA cap-binding protein eukaryotic translation initiation factor 4E (eIF4E) gave rise to a plethora of paralog genes across eukaryotes that underwent further functional diversification in RNA metabolism. The ability to take different roles is due to eIF4E promiscuity in binding many partner prot...
Source: Biological Reviews of the Cambridge Philosophical Society - August 8, 2023 Category: Biology Authors: Greco Hern ández Paula Vazquez-Pianzola Source Type: research
eIF4E as a molecular wildcard in metazoans RNA metabolism
Biol Rev Camb Philos Soc. 2023 Aug 8. doi: 10.1111/brv.13005. Online ahead of print.ABSTRACTThe evolutionary origin of eukaryotes spurred the transition from prokaryotic-like translation to a more sophisticated, eukaryotic translation. During this process, successive gene duplication of a single, primordial eIF4E gene encoding the mRNA cap-binding protein eukaryotic translation initiation factor 4E (eIF4E) gave rise to a plethora of paralog genes across eukaryotes that underwent further functional diversification in RNA metabolism. The ability to take different roles is due to eIF4E promiscuity in binding many partner prot...
Source: Biological Reviews of the Cambridge Philosophical Society - August 8, 2023 Category: Biology Authors: Greco Hern ández Paula Vazquez-Pianzola Source Type: research
Evaluation of the immunoprotective effects of eight recombinant proteins from Baylisascaris schroederi in mice model
Baylisascaris schroederi is the most common and harmful intestinal parasitic nematode of giant pandas, causing ascariasis. Although drug deworming is the main measure to control ascariasis in captive giant pandas... (Source: Parasites and Vectors)
Source: Parasites and Vectors - July 28, 2023 Category: Microbiology Authors: Lang Xiong, Ling Chen, Yanxin Chen, Nengxing Shen, Ruiqi Hua and Guangyou Yang Tags: Research Source Type: research
Exploration of Parascaris species in three different Equus populations in China
The roundworms, Parascaris spp., are important nematode parasites of foals and were historically model organisms in the field of cell biology, leading to many important discoveries. According to karyotype, ascari... (Source: Parasites and Vectors)
Source: Parasites and Vectors - June 15, 2023 Category: Microbiology Authors: Mengchao Zhou, Yaxian Lu, Lei Han, Maolin Lu, Chunyu Guan, Jie Yu, Hetong Liu, Denghui Chen, Hongjia Li, Yuling Yang, Lu Zhang, Lihong Tian, Quan Liu and Zhijun Hou Tags: Research Source Type: research
Baylisascaris procyonis Roundworm Infection in Child with Autism Spectrum Disorder, Washington, USA, 2022
We describe a case of Baylisascaris procyonis roundworm infection in a child in Washington, USA, with autism spectrum disorder. Environmental assessment confirmed nearby raccoon habitation and B. procyonis eggs. B. procyonis infections should be considered a potential cause of human eosinophilic meningitis, particularly among young children and persons with developmental delays.PMID:37209678 | DOI:10.3201/eid2906.230290 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - May 20, 2023 Category: Infectious Diseases Authors: Beth A Lipton Hanna N Oltean Roger B Capron Arran Hamlet Susan P Montgomery Rebecca J Chancey Victoria J L Konold Katherine E Steffl Source Type: research
Baylisascaris procyonis Roundworm Infection in Child with Autism Spectrum Disorder, Washington, USA, 2022
B. A. Lipton et al. (Source: Emerging Infectious Diseases Journal)
Source: Emerging Infectious Diseases Journal - May 10, 2023 Category: Infectious Diseases Source Type: research
Seroprevalence and associated risk factors of strongyloidiasis in indigenous communities and healthcare professionals from Brazil
by Vamilton Alvares Santar ém, Fernando Rodrigo Doline, João Henrique Farinhas dos Santos, Isabella Braghin Ferreira, Bruna Barroso Gomes, Dirce Mary Correa Meisel, Leandro Meneguelli Biondo, Susana Angélica Zevallos Lescano, Ronaldo Cesar Borges Gryschek, Rogério Giuffrida, Andrea Pires dos Santos, Louise Bach Kmetiuk, F abiana Martins de Paula, Alexander Welker BiondoStrongyloides stercoralis, a pathogenic roundworm, is considered endemic in several tropical and subtropical areas worldwide. Indigenous populations have the highest soil-transmitted helminthiases-related mortality rates, but the prevalence and risk fact...
Source: PLoS Neglected Tropical Diseases - April 27, 2023 Category: Tropical Medicine Authors: Vamilton Alvares Santar ém Source Type: research
Further studies on the morphology of Baylisascaris transfuga (Rudolphi, 1819) (Nematoda: Ascaridomorpha: Ascarididae) from the polar bear Ursus maritimus Phipps (Carnivora: Ursidae)
Syst Parasitol. 2023 Apr 4. doi: 10.1007/s11230-023-10087-3. Online ahead of print.ABSTRACTBaylisascaris transfuga (Rudolphi, 1819) is a common parasitic nematode in the digestive tract of various species of bears worldwide, with great veterinary significance. However, our present knowledge on the morphology of B. transfuga remains insufficient. In the present study, the detailed morphology of B. transfuga was studied using light and scanning electron microscopy (SEM), based on specimens collected from the polar bear Ursus maritimus Phipps (Carnivora: Ursidae) in the Shijiazhuang Zoo, China. The results revealed some morph...
Source: Systematic Parasitology - April 4, 2023 Category: Parasitology Authors: Liang Li Hui-Xia Chen Source Type: research
Further studies on the morphology of Baylisascaris transfuga (Rudolphi, 1819) (Nematoda: Ascaridomorpha: Ascarididae) from the polar bear Ursus maritimus Phipps (Carnivora: Ursidae)
Syst Parasitol. 2023 Apr 4. doi: 10.1007/s11230-023-10087-3. Online ahead of print.ABSTRACTBaylisascaris transfuga (Rudolphi, 1819) is a common parasitic nematode in the digestive tract of various species of bears worldwide, with great veterinary significance. However, our present knowledge on the morphology of B. transfuga remains insufficient. In the present study, the detailed morphology of B. transfuga was studied using light and scanning electron microscopy (SEM), based on specimens collected from the polar bear Ursus maritimus Phipps (Carnivora: Ursidae) in the Shijiazhuang Zoo, China. The results revealed some morph...
Source: Systematic Parasitology - April 4, 2023 Category: Parasitology Authors: Liang Li Hui-Xia Chen Source Type: research
Small bowel obstruction caused by massive ascariasis: two case reports
CONCLUSION: The type of surgery undertaken is determined by the results of the laparotomy. If the bowel was found to be intact and the obstruction was at the ileum level, milking worms to the cecum can be done with caution to avoid trauma to the bowel wall. Primary anastomosis after resection of a necrotic bowel segment and removal of the worm bolus is a suitable method for treatment of the ascariasis obstruction.PMID:36923774 | PMC:PMC10010792 | DOI:10.1097/MS9.0000000000000224 (Source: Annals of Medicine)
Source: Annals of Medicine - March 16, 2023 Category: Internal Medicine Authors: Abdullahi Y Ali Abdishakur Mohamed Abdi Ervin Mambet Source Type: research
