Scientists Identify Strategy to Prevent Renal Failure, Also Hit on Opportunities to Improve Cancer Treatment (Roswell Park Cancer Institute)
Acute kidney injury (AKI), also known as acute renal failure, is one of the main contributors to death and disability worldwide, yet no preventive treatment for the condition has been established. In a new study published in the journal Cell Death and Differentiation, a team of researchers led by scientists from Roswell Park Cancer Institute (RPCI) reports that they have identified 10 genes whose inhibition appears to protect kidney cells. The findings point the way to strategies for preventing ... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - November 23, 2015 Category: Cancer & Oncology Source Type: news

Kitchen Tox: beware of the durian
ThamKC/shutterstock.com 3 out of 5 stars Durian Induced Hyperkalaemia. Leo CLB et al. Med J Malaysia 2011 Mar;66:66-67. Full Text Durian, a spiky, coconut-sized fruit native to Malaysia and grown throughout southeast Asia, is known for its distinctive aroma that some have compared to ripe Limburger cheese. The Oxford Companion to Food notes that others have compared the smell of durian to “the civet cat, sewage, stale vomit, onions, and cheese; while one disaffected visitor to Indonesia declared that the eating of the flesh was not much different from having to consume used surgical swabs.” Anthony Bourdain...
Source: The Poison Review - November 18, 2015 Category: Toxicology Authors: Leon Tags: Medical durian hyperkalemia kitchen toxicology potassium Source Type: news

Research yields potential treatment approach for glycogen storage disease
Contact: Sarah AveryPhone: 919-660-1306Email: sarah.avery@duke.edu FOR IMMEDIATE RELEASE on Wednesday, Nov. 18, 2015 DURHAM, N.C. and SINGAPORE – Researchers from the Duke-NUS Graduate Medical School Singapore (Duke-NUS) and Duke Medicine have identified a potential treatment strategy for an often-fatal inherited glycogen storage disease. E-published ahead of print recently in the Journal of Hepatology, the study provides much-needed hope for the management of glycogen storage disease Ia, known as GSDIa or von Gierke disease, a genetic metabolic disorder that requires lifelong dietary therapy.  Patients with the disorde...
Source: DukeHealth.org: Duke Health Features - November 18, 2015 Category: Pediatrics Tags: Duke Medicine Source Type: news

TASER(®) electronic control device-induced rhabdomyolysis and renal failure: a case report - Gleason JB, Ahmad I.
Many law enforcement agencies around the United States are employing the use of TASER(®) electronic control devices (TASER(®) International Inc.) to subdue combative suspects. Since its inception the TASER(®) has had a temporal association with reports ... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - November 15, 2015 Category: Global & Universal Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Lupin launches generic PhosLo capsules in US market
Lupin has launched Calcium Acetate capsules, used in treating hyperphosphatemia in end stage renal failure, in the US after getting approval from United States Food and Drug Administration (USFDA). (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - October 26, 2015 Category: Pharmaceuticals Source Type: news

TCT 2015: Medtronic touts CoreValve TAVI real-world registry data
Update: Added data from study of new patient populations Medtronic (NYSE:MDT) said today it released the 1st real-world registry study of its CoreValve transcatheter aortic valve implant, reporting outcomes in-line with its clinical trials of the device. The medtech giant also released new data from 3 studies focusing on new patient populations with significant comorbidities today. Data from all of the CoreValve studies was presented at the annual Transcatheter Cardiovascular Therapeutics conference in San Franscisco. The 6,160-patient Society of Thoracic Surgeons and American College of Cardiology TVT registry study repo...
Source: Mass Device - October 13, 2015 Category: Medical Equipment Authors: Fink Densford Tags: Cardiac Implants Cardiovascular Catheters Clinical Trials Medtronic TCT 2015 Source Type: news

Acute Kidney Injury in Neonates
Acute kidney injury in the neonate is due to a myriad of causes, often resulting in death from ultimate renal failure. Outcomes for the infant are dependent on underlying cause, degree of injury, and response to treatment. Improved outcomes can be seen with prompt recognition and appropriate treatment of the neonate who develops acute kidney injury. (Source: NeoReviews recent issues)
Source: NeoReviews recent issues - October 1, 2015 Category: Pediatrics Authors: Yanik, M., Askenazi, D., Ambalavanan, N. Tags: Pediatric Drug Labeling Update Articles Source Type: news

Case report: use of ECMO in colchicine poisoning
Colchicum autumnale (Autumn crocus) 3.5 out of 5 stars Extracorporeal life support in the treatment of colchicine poisoning. Boisramé-Helms J et al. Clin Toxicol 2015;53:827-829. Abstract Colchicine toxicity occurs roughly in 3 phases. During the initial 24 hours, severe gastrointestinal symptoms — nausea, vomiting, and diarrhea — can cause hypotension and shock if fluid losses are not adequately replaced. During the second phase, severe toxicity can manifest with pancytopenia, sepsis, rhabdomyolysis, and renal failure. In addition, within days after ingestion, patients can develop cardiogenic shock and sudden cardia...
Source: The Poison Review - September 11, 2015 Category: Toxicology Authors: Leon Tags: Medical autumn crocus colchicine poisoning colchicum autumnale ECLS ECMO extracorporeal life support extracorporeal membrane oxygenation Source Type: news

A rare case of acute renal failure related to amanita proxima ingestion - Mancini A, Assisi F, Balestreri S, Angelini P, Bozzi M, Cuzzola C, Davanzo F, Giancaspro V, Laraia E, Nisi MT, Proscia A, Tarantino G, Vitale O, Petrarulo F.
OBJECTIVE: The first cases of acute renal tubulopathy related to Amanita proxima poisoning were described in 1994; the mushroom contains a toxin responsible for the allenic-norleucine syndrome, characterised by a kidney damage that occur earlier than in Co... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - September 10, 2015 Category: Global & Universal Tags: Home and Consumer Product Safety Source Type: news

Renal Failure: Symptoms, Causes & Treatment
Renal failure is divided into Chronic Renal Failure and Acute Renal Failure. The information below concerns the basics of renal failure. Acute renal failure means a person's kidneys suddenly lose their ability to filter waste products from their blood. When a person's kidneys stop working, fluids and waste products build up in their body, which can cause issues that may be fatal. (Source: Disabled World)
Source: Disabled World - July 17, 2015 Category: Disability Tags: Health and Disability Source Type: news

Renal Failure: Symptoms, Causes and Treatment
Information regarding the basics of renal failure, a condition when the kidneys lose the ability to filter waste products from the blood (Source: Disabled World)
Source: Disabled World - July 17, 2015 Category: Disability Tags: Health and Disability Source Type: news

Hospital readmissions for sepsis are highly common, extremely costly
UCLA Health Sciences Dr. Dong Chang The Affordable Care Act created several national initiatives aimed at reducing hospital readmission rates for heart attacks, congestive heart failure and other common high-risk conditions. But there is still no national program intended to address sepsis, a potentially life-threatening illness caused by infection. Now, a new UCLA study found that sepsis accounts for roughly the same percentage of hospital readmissions in California as heart attacks and congestive heart failure — and that it costs the health care system more than both of them combined. The research, conducted by the U...
Source: UCLA Newsroom: Health Sciences - July 8, 2015 Category: Universities & Medical Training Source Type: news

Life Is Not a Premortality Condition, and Death Is Not Treatment Failure
"Medical research is making such astounding progress that soon none of us will be well." --Aldous Huxley In my last blog post I discussed the importance of dying well and with dignity -- at home, at peace, sent off by a loving family, not in an impersonal and hectic hospital environment, among strangers, your failing body tortured by painful procedures and probed by ubiquitous tubes in a futile effort to cheat death. This week my issue is living well and without unnecessary fear of disease. Mark Cuban provides the perfect example of how excessive heath concerns are unhealthy. He is a brilliant Internet, entertainment, a...
Source: Healthy Living - The Huffington Post - April 22, 2015 Category: Consumer Health News Source Type: news

Life Is Not a Premortality Condition, and Death Is Not Treatment Failure
"Medical research is making such astounding progress that soon none of us will be well." --Aldous Huxley In my last blog post I discussed the importance of dying well and with dignity -- at home, at peace, sent off by a loving family, not in an impersonal and hectic hospital environment, among strangers, your failing body tortured by painful procedures and probed by ubiquitous tubes in a futile effort to cheat death. This week my issue is living well and without unnecessary fear of disease. Mark Cuban provides the perfect example of how excessive heath concerns are unhealthy. He is a brilliant Internet, entertainment, a...
Source: Science - The Huffington Post - April 22, 2015 Category: Science Source Type: news

PPIs Linked to Kidney Failure in Seniors
(MedPage Today) -- Older patients taking proton pump inhibitors had doubled risk for renal failure. (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - April 19, 2015 Category: Gastroenterology Source Type: news