Hydroxyethyl Starch for Blood Volume Linked to Renal FailureHydroxyethyl Starch for Blood Volume Linked to Renal Failure
A systematic review excluding questionable literature reveals the potential harm of using hydroxyethyl starch in resuscitation fluids. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 19, 2013 Category: Consumer Health News Tags: Critical Care News Source Type: news

Gambia: 18 - Year Old Youth Seeks Assistance for Overseas Treatment
[Foroyaa]Kumana Corrah is an 18 year old youth who was referred to the Nephrology unit of the Royal Victoria Teaching Hospital with diagnosis of chronic renal failure (MRC No: 2010/24900). (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - February 18, 2013 Category: African Health Source Type: news

Post-Infarction Cardiac Remodeling in Chronic Kidney DiseasePost-Infarction Cardiac Remodeling in Chronic Kidney Disease
A novel animal model for cardiorenal syndrome suggests that renin activity is responsible for adverse ventricular remodeling after myocardial infarction associated with renal failure. Laboratory Investigation (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 15, 2013 Category: Consumer Health News Tags: Pathology & Lab Medicine Journal Article Source Type: news

MMWR: synthetic pot suspected in cases of kidney failure
4.5 out of 5 stars Acute Kidney Injury Associated with Synthetic Cannabinoid Use — Multiple States, 2012. MMWR 2013 Feb 15;62:93-98. Full Text About a year ago, TPR posted that several cases of acute renal failure following the use of synthetic cannabinoids had been reported in Wyoming. After this, the story seemed to drop off the map, and we were unable to obtain any additional information despite several calls to the Wyoming Department of Health. The current issue of MMWR contains at important update. Following an alert issued after the 4 Wyoming cases were reported, 12 additional cases were detected in several st...
Source: The Poison Review - February 15, 2013 Category: Toxicology Authors: Leon Tags: Medical acute renal failure blueberry spice kidney injury synthetic cannabinoid Wyoming Source Type: news

Dual renin angiotensin system blockade: too many cons
Any benefit of dual blockade of the renin angiotensin system is limited to its effects on surrogate endpoints, and outweighed by an excessive risk for adverse events such as hypotension, hyperkalemia, and renal failure, argue hypertension experts. (Source: MedWire News - Heart Failure)
Source: MedWire News - Heart Failure - February 4, 2013 Category: Cardiology Source Type: news

Dual renin angiotensin system blockade: too many cons
Any benefit of dual blockade of the renin angiotensin system is limited to its effects on surrogate endpoints, and outweighed by an excessive risk for adverse events such as hypotension, hyperkalemia, and renal failure, argue hypertension experts. (Source: MedWire News - Hypertension)
Source: MedWire News - Hypertension - February 3, 2013 Category: Cardiology Source Type: news

Dual renin angiotensin system blockade: too many cons
Any benefit of dual blockade of the renin angiotensin system is limited to its effects on surrogate endpoints, and outweighed by an excessive risk for adverse events such as hypotension, hyperkalemia, and renal failure, argue hypertension experts. (Source: MedWire News - Heart Failure)
Source: MedWire News - Heart Failure - February 3, 2013 Category: Cardiology Source Type: news

No Benefit to Dual RAS Blockade in Meta-AnalysisNo Benefit to Dual RAS Blockade in Meta-Analysis
In fact, combined ACE-inhibitor and ARB therapy, given for a variety of disorders, was associated with increased risks of hyperkalemia, hypotension, and renal failure as well as drug withdrawal due to adverse effects. Researchers are hoping their results are the final nail in the coffin for dual RAS blockade. Heartwire (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 30, 2013 Category: Consumer Health News Tags: Cardiology News Source Type: news

No benefit to dual RAS blockade in meta-analysis
In fact, combined ACE-inhibitor and ARB therapy, given for a variety of disorders, was associated with increased risks of hyperkalemia, hypotension, and renal failure as well as drug withdrawal due to adverse effects. Researchers are hoping their results are the final nail in the coffin for dual RAS blockade. (Source: theHeart.org)
Source: theHeart.org - January 29, 2013 Category: Cardiology Source Type: news

Treating Amanita phalloides poisoning: is silibinin superior to chicken dung?
Milk thistle 2.5 out of 5 stars Amanita phalloides poisoning and treatment with silibinin in the Australian Capital Territory and New South Wales. Roberts DM et al. Med J Aust 3013 Jan 21;198:43-47 Abstract In one of his published works, the second-century Roman physician Galen related an anecdotal method of treating mushroom poisoning: I have heard of a physician of Mysia who administered Fowl’s dung to persons suffering form fungus poisoning, and I myself have experimented with the remedy. I have used finally powdered dung mixed with water or mixed with honey and vinegar The patients immediately on drinking the ...
Source: The Poison Review - January 25, 2013 Category: Toxicology Authors: Leon Tags: Medical amanita phalloides Australia milk thistle mushroom poisoning silibinin silymarin Source Type: news

What factors need to be considered when dosing patients on renal replacement therapies?
Source: South West Medicines Information and Training Area: Evidence > Medicines Q & A There are a number of factors that need to be considered when dosing patients on renal replacement therapy (RRT). Consider the drug, the patient and the type of RRT. Alteration of drug dosage is only necessary if renal clearance exceeds 25% of total body clearance. Drugs which are cleared by the kidneys are usually dialysed, and vice versa, although there are some anomalies. Dose adjustment for RRT is only necessary for drugs that require dose adjustment because of the presence of renal failure. No RRT is as effective as the n...
Source: NeLM - Medicines Q and A - January 22, 2013 Category: Drugs & Pharmacology Source Type: news

Renal Failure Hikes Mortality with LVADs (CME/CE)
(MedPage Today) -- Among patients receiving a left ventricular assist device (LVAD) for end-stage heart failure, developing acute renal failure after implantation predicted a lower likelihood of surviving the next year, a single-center study showed. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - January 2, 2013 Category: Cardiology Source Type: news

RAGE Splicing Variants in Mammals
The receptor for advanced glycation end products (RAGE) is a multiligand receptor of environmental stressors which plays key roles in pathophysiological processes, including immune/inflammatory disorders, Alzheimer’s disease, diabetic arteriosclerosis, tumorigenesis, and metastasis. Besides the full-length RAGE protein in humans nearly 20 natural occurring RAGE splicing variants were described on mRNA and protein level. These naturally occurring isoforms are characterized by either N-terminally or C-terminally truncations and are discussed as possible regulators of the full-length RAGE receptor either by competitive ...
Source: Springer protocols feed by Protein Science - January 1, 2013 Category: Biochemistry Source Type: news

Nephrology: Images in Clinical Medicine
Editor: V. Dimov, M.D., Assistant Professor at University of ChicagoCalciphylaxis is a syndrome of systemic medial calcification of arteries leading to tissue necrosis. Lancet, 3/3014.Bladder Stone. NEJM, 06/2012.Fordyce ' s Angiokeratomas. NEJM, 03/2012.Patent Urachus. NEJM, 10/2011.Renal Tuberculosis. NEJM, 09/2011.Agitation Associated with Acute Bladder Obstruction. NEJM, 10/2010.Bladder Diverticula. NEJM, 08/2010.Abdominal “Knocking” Due to Calcifications in a Continent Urinary Diversion. NEJM, 04/2010.Renal Failure from Vitamin C after Transplantation. NEJM, 01/2008.Green Urine. NEJM, 03/2008.Crystalluria from Acy...
Source: Clinical Cases and Images - August 22, 2009 Category: General Medicine Tags: Images Nephrology Source Type: news