New mineralocorticoid-receptor antagonist passes in phase 2 study
Patients treated with the drug, known only as BAY94-8862 at the moment, had a significantly lower risk of hyperkalemia than patients treated with spironolactone, as well as a lower risk of worsening renal failure. The drug also reduced BNP levels as much as spironolactone. (Source: theHeart.org)
Source: theHeart.org - May 30, 2013 Category: Cardiology Source Type: news
Serelaxin Reduces Dyspnea in HF-PEF PatientsSerelaxin Reduces Dyspnea in HF-PEF Patients
Like the overall trial, which reported no improvement in cardiovascular death or hospitalization for heart or renal failure through day 60, there was no significant treatment effect in patients with HF-PEF or HF-REF. Heartwire (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 28, 2013 Category: Consumer Health News Tags: Cardiology News Source Type: news
Serelaxin reduces dyspnea in HFpEF patients in first 24 hours: RELAX-AHF analysis
Like the overall trial, which reported no improvement in cardiovascular death or hospitalization for heart or renal failure through day 60, there was no significant treatment effect in patients with HFpEF or HFrEF. (Source: theHeart.org)
Source: theHeart.org - May 27, 2013 Category: Cardiology Source Type: news
Serelaxin reduces dyspnea in HF-PEF patients in first 24 hours: RELAX-AHF analysis
Like the overall trial, which reported no improvement in cardiovascular death or hospitalization for heart or renal failure through day 60, there was no significant treatment effect in patients with HF-PEF or HF-REF. (Source: theHeart.org)
Source: theHeart.org - May 27, 2013 Category: Cardiology Source Type: news
Digoxin toxicity: check the magnesium level!
3 out of 5 stars
Digoxin Toxicity with Normal Digoxin and Serum Potassium Levels: Beware of Magnesium, the Hidden Malefactor. Rao MPR et al. J Emerg Med 2013 May 16 [Epub ahead of print]
Abstract
This case report from Oman describes at 66-year-old woman (inexplicably described as “elderly”) who presented to hospital with one day of nausea, vomiting, abdominal distress, and palpitations. Her medications included furosemide, spironolactone, digoxin, carvedilol, lisinopril, metformin, and calcium. Initial EKGs showed evidence of junctional tachycardia and digoxin effect.
The treating physicians initially consider...
Source: The Poison Review - May 23, 2013 Category: Toxicology Authors: Leon Tags: Medical digitalis digoxin toxicity hypomagnesemia magnesium potassium Source Type: news
Widespread But Neglected Disease Leptospirosis A Significant Health Threat In Africa
The newest public health threat in Africa, scientists have found, is coming from a previously unknown source: the banded mongoose. Leptospirosis, the disease is called. And the banded mongoose carries it. Leptospirosis is the world's most common illness transmitted to humans by animals. It's a two-phase disease that begins with flu-like symptoms. If untreated, it can cause meningitis, liver damage, pulmonary hemorrhage, renal failure and death... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 16, 2013 Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news
Widespread but neglected disease a health threat in Africa, Virginia Tech researchers say
(Virginia Tech) Virginia Tech researchers have identified leptospirosis as a significant health threat in Botswana. The world's most common disease transmitted to humans by animals, according to the World Health Organization, leptospirosis is a two-phase disease that begins with flu-like symptoms but can cause meningitis, liver damage, pulmonary hemorrhage, renal failure, and even death if untreated. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 14, 2013 Category: Global & Universal Source Type: news
Human disease leptospirosis identified in new species, the banded mongoose, in Africa
(National Science Foundation) Leptospirosis is the world's most common illness transmitted to humans by animals. It's a two-phase disease that begins with flu-like symptoms. If untreated, it can cause meningitis, liver damage, pulmonary hemorrhage, renal failure and death. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 14, 2013 Category: Global & Universal Source Type: news
Organophosphate poisoning-induced acute renal failure - Cavari Y, Landau D, Sofer S, Leibson T, Lazar I.
BACKGROUND: Acute kidney injury as a direct complication of organophosphate poisoning has rarely been described and its etiology is unclear. CASE: A 17-year-old adolescent girl was admitted to the pediatric intensive care unit after a suicidal attempt with... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - May 11, 2013 Category: Global & Universal Tags: Poisoning Source Type: news
Acetaminophen (paracetamol) causing renal failure: Report on 3 pediatric cases - Le Vaillant J, Pellerin L, Brouard J, Eckart P.
Renal failure secondary to acetaminophen poisoning is rare and occurs in approximately 1-2 % of patients with acetaminophen overdose. The pathophysiology is still being debated, and renal acetaminophen toxicity consists of acute tubular necrosis, without ... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - May 2, 2013 Category: Global & Universal Tags: Age: Adolescents Source Type: news
What Causes Hypercalcemia?
Discussion
Calcium homeostasis is regulated by mechanisms involving the absorption from the gastrointestinal tract, bone deposition and resorption, and renal excretion. To review Vitamin D homeostasis click here.
Serum calcium is found in three forms: free (47%), protein bound (43%) and diffusable calcium complexes (10%). The protein binding proteins are albumin (80%) and globulin (20%). The free calcium is the most important biologically. Acidosis also increases free calcium and alkalosis decreases free calcium.
Problems associated with hypercalcemia include nausea, emesis, abdominal pain, constipation, polyuria, dehydra...
Source: PediatricEducation.org - March 25, 2013 Category: Pediatrics Authors: Donna M. D'Alessandro, M.D. Tags: Uncategorized Source Type: news
Study Finds Fewer Complications After Off-Pump Bypass Surgery Versus On-Pump For High-Risk Patients
Bypass surgery done without a heart-lung machine, known as off-pump, may provide better post-operative outcomes than on-pump bypass surgery for high-risk patients, according to research presented at the American College of Cardiology's 62nd Annual Scientific Session. In the first study to look specifically at on-pump versus off-pump bypass surgery among patients deemed to be at high operative risk, researchers examined the primary endpoint of patients' combined outcomes of all-cause death, stroke, heart attack or renal failure requiring new hemodialysis within 30 days of their procedure... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 14, 2013 Category: Consumer Health News Tags: Cardiovascular / Cardiology Source Type: news
Missed and Erroneous Diagnoses Common in Primary Care Visits Missed and Erroneous Diagnoses Common in Primary Care Visits
Diagnostic errors are common and include missed diagnosis of pneumonia, decompensated congestive heart failure, and acute renal failure. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 26, 2013 Category: Consumer Health News Tags: Internal Medicine News Source Type: news
Changing the face of Midaortic Syndrome treatment to save Sofia
The American Journal of Transplantation recently published a paper, documenting a first-of-its-kind treatment for midaortic syndrome, as performed by Khashayar Vakili, MD, of Boston Children’s Department of Surgery and Heung Bae Kim, MD, director of Boston Children’s Pediatric Transplant Center.
In the following blog Marcus Groff, father of the patient described in the Journal of Transplantation, writes about his daughter’s revolutionary surgery at Boston Children’s.
Sofia
Two years ago my wife and I were anxiously waiting outside the NICU of our local hospital at four in the morning. Inside, our...
Source: Thrive, Children's Hospital Boston - February 25, 2013 Category: Pediatrics Authors: Guest Blogger Tags: All posts Diseases & conditions Heart conditions Our patients’ stories Heung Bae Kim kidney transplant midaortic syndrome Midaortic Syndrome and Renovascular Hypertension (MAS/RVH) Program our patients' stories Pediatric Transplant Cen Source Type: news
SynCardia Total Artificial Heart Patient with End-Stage Renal Failure Recovers Kidney Function after Two Months of Support
20-Year-Old Tiernee Gonzalez Begins Producing Urine Day Before Scheduled Surgery to Implant Permanent Catheter
TUCSON, Ariz., Feb. 21, 2013 -- (Healthcare Sales & Marketing Network) -- At only 20 years old, Tiernee Gonzalez has been battling two major ... Devices, CardiologySynCardia Systems, temporary Total Artificial Heart, heart failure (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - February 21, 2013 Category: Pharmaceuticals Source Type: news
