Chronic renal failure and an increased risk of osteoporosis
According to researchers in Italy, patients who had chronic renal failure and chronic treatment with anticoagulants or antiepileptic medications were at a higher risk for osteoporosis.
Healio (Source: Society for Endocrinology)
Source: Society for Endocrinology - February 16, 2016 Category: Endocrinology Source Type: news
Medtronic wins expanded PMA for CoreValve
The FDA cleared expanded indications for Medtronic‘s (NYSE:MDT) CoreValve TAVR devices, now cleared for use in patients with end-stage renal disease and those with low-grade, low-flow aortic stenosis.
Medtronic won approval from the FDA to modify the CoreValve’s labeling in November which included both its CoreValve and CoreValve Evolut R systems.
The changes to the labeling were approved based on Medtronic’s CoreValve U.S. expanded use study of high and very-high-risk subjects at need for aortic valve replacements, according to an email FierceMedicalDevices received from a Medtronic spokesperson.
Data from theÂ...
Source: Mass Device - February 4, 2016 Category: Medical Equipment Authors: Fink Densford Tags: Cardiac Implants Cardiovascular Food & Drug Administration (FDA) Regulatory/Compliance Replacement Heart Valves Medtronic Source Type: news
MassDevice.com +3 | The top 3 medtech stories for February 1, 2016
Say hello to MassDevice +3, a bite-sized view of the top three medtech stories of the day. This feature of MassDevice.com’s coverage highlights our 3 biggest and most influential stories from the day’s news to make sure you’re up to date on the headlines that continue to shape the medical device industry.
3. Medtronic gets into renal care with Bellco acquisition
Medtronic said that it acquired renal care products make Bellco for an indisclosed amount and plans to fold it into a newly created renal care solutions division.
Fridley, Minn.-based Medtronic said Mirandola, Italy-based Bellco makes devi...
Source: Mass Device - February 1, 2016 Category: Medical Equipment Authors: MassDevice Tags: News Well Plus 3 Source Type: news
Medtronic gets into renal care with Bellco acquisition
Medtronic (NYSE:MDT) said today that it acquired renal care products make Bellco for an undisclosed amount and plans to fold it into a newly created renal care solutions division.
Fridley, Minn.-based Medtronic said Mirandola, Italy-based Bellco makes devices designed to treat end-stage renal failure, multiple organ failure and sepsis, including dialyzers and chronic and acute dialysis machines. The products are on the market in more than 50 nations, Medtronic said.
“ESRD patients require dialysis for the remainder of their lives, or until a viable kidney transplant becomes available. We believe Medtronic’s ...
Source: Mass Device - February 1, 2016 Category: Medical Equipment Authors: Brad Perriello Tags: Dialysis Mergers & Acquisitions Wall Street Beat Bellco Medtronic Renal Source Type: news
Extracorporeal treatment for digoxin toxicity: just say no
3 out of 5 stars
Extracorporeal treatment for digoxin poisoning: systematic review and recommendations from the EXTRIP Workgroup. Mowry JB et al. Clin Toxicol 2016 Feb;54:103-14.
Abstract
“Forced diuresis, and hemodialysis are ineffective in enhancing the elimination of digoxin because of its large volume of distribution (4-10 L/kg), which makes it relatively inaccessible to these techniques.” Goldfrank’s Toxicologic Emergencies (Tenth Edition, 2015)
That one sentence from the latest edition of Goldfrank’s tells you all you need to know about the use of extracorporeal treatment (ECTR)  in digoxin...
Source: The Poison Review - January 28, 2016 Category: Toxicology Authors: Leon Tags: Medical digoxin toxicity extracorporeal treatment extrip Fab fragment hemodialysis hemoperfusion Source Type: news
Review of synthetic cannabinoids out-of-date as soon as it’s published
3 out of 5 stars
A systematic review of adverse events arising from the use of synthetic cannabinoids and their associated treatment. Tait RJ et al. Clin Toxicol 2016 Jan;54:1-13.
Abstract
This paper review clinical literature related to use of synthetic cannabinoids (SCs) through the end of 2015. Although it seems comprehensive, and cites 108 references, it is of course already at least 18 months out-of-date. The number of cases involving exposure to SC surged during 2015. For example, although the authors of this paper identified 22 deaths associated with SCs, according to CDC data in the first 6 months of 2015 alone ...
Source: The Poison Review - January 20, 2016 Category: Toxicology Authors: Leon Tags: Medical K2 spice synthetic cannabinoids systematic review Source Type: news
Teach Providers to Appreciate the Small Parts of the Job
When the public thinks or hears about firefighting, what typically comes to mind are all the big jobs: multi-alarm fires, extrications, hazardous materials mitigations, collapsed structure and confined space rescues—the kinds of calls we worry about but also somewhat ironically look forward to.
This all looks a little different on the medical side. Although many of the things we encounter in suppression can certainly be dramatic and critically important, there are many more opportunities to save or change the course of a life on the EMS end of things. That’s not to belittle or to trivialize the importance of fire suppr...
Source: JEMS Administration and Leadership - January 18, 2016 Category: Emergency Medicine Authors: Neal Richmond, MD Tags: Leadership & Professionalism Columns Source Type: news
A lethal danger in the home: turpentine poisoning - Güzel A, Açıkgöz M.
Turpentine is an oleoresin obtained from various species of pine. In turpentine poisoning, various signs and symptoms of toxicity may develop, including hematuria, renal failure, loss of vision, chest pain, vomiting, severe coughing, gastroesophageal hemor... (Source: SafetyLit)
Source: SafetyLit - January 11, 2016 Category: Global & Universal Tags: Home and Consumer Product Safety Source Type: news
LIRA-RENAL: Liraglutide Safe in Diabetes With Renal FailureLIRA-RENAL: Liraglutide Safe in Diabetes With Renal Failure
Data from the LIRA-RENAL study detailing use of liraglutide in patients with type 2 diabetes and moderate kidney disease have been published. Medscape Medical News (Source: Medscape Diabetes Headlines)
Source: Medscape Diabetes Headlines - December 24, 2015 Category: Endocrinology Tags: Diabetes & Endocrinology News Source Type: news
An In Vitro Murine Model of Vascular Smooth Muscle Cell Mineralization
Vascular calcification (VC) is seen ubiquitously in aging blood vessels and prematurely in disease states like renal failure. It is thought to be driven by a number of systemic and local factors that lead to extra-osseous deposition of mineral in the vascular wall and valves as a common endpoint. The response of resident vascular smooth muscle cell to these dystrophic signals appears to be important in this process. Whilst in vivo models allow the observation of global changes in a pro-calcific environment, identifying the specific cells and mechanisms involved has been largely garnered from in vitro experiments, which pro...
Source: Springer protocols feed by Molecular Medicine - December 22, 2015 Category: Molecular Biology Source Type: news
Reduction of contrast medium volume and radiation dose in CTA scans
Researchers have shown that a CTA scan (a scan of the arteries) can be performed with a contrast medium volume reduction of up to 75% and up to 50% reduction in radiation dose. CT scans using contrast medium are the third most common cause of acute renal failure and renal insufficiency as a result of hospital treatments. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - December 21, 2015 Category: Science Source Type: news
Medical News Today: Could testosterone therapy benefit men with type 2 diabetes?
Researchers have established a link between testosterone, type 2 diabetes, obesity and renal failure, leading them to ask if testosterone could be a metabolic hormone. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 30, 2015 Category: Consumer Health News Tags: Diabetes Source Type: news
Quantitation of Parathyroid Hormone in Serum or Plasma by Liquid Chromatography-Tandem Mass Spectrometry
Parathyroid hormone (PTH), an 84 amino acid peptide hormone, is an important regulator of calcium homeostasis. Quantitation of PTH in serum is useful for the diagnosis of primary hyperparathyroidism, hypoparathyroidism, and for monitoring osteodystrophy in patients with renal failure. The biological activity of PTH arises from binding of PTH (N terminus) to its target receptor (D’Amour et al., Kidney Int 68: 998–1007, 2005). Several C-terminal and N-terminal fragments circulate in normal subjects. Recent studies have demonstrated that accurate quantitation of PTH fragments may be of clinical value. In this chap...
Source: Springer protocols feed by Imaging/Radiology - November 27, 2015 Category: Radiology Source Type: news
