The impact of common co-morbidities (as measured using the Charlson index) on hip fracture risk in elderly men: a population-based cohort study - Reyes C, Estrada P, Nogues X, Orozco P, Cooper C, Díez-Pérez A, Formiga F, Mácias JG, Prieto-Alhambra D.
We used a large population-based health care database to determine the impact of common co-morbidities on hip fracture risk amongst elderly men. We demonstrated that diabetes, chronic obstructive pulmonary disease, renal failure, HIV infection, dementia, a... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - April 4, 2014 Category: Global & Universal Tags: Age: Elder Adults Source Type: news
Ceftriaxone Linked to Renal Failure in ChildrenCeftriaxone Linked to Renal Failure in Children
A retrospective study has linked therapeutic doses of ceftriaxone with renal failure in kids and has suggested that early treatment can be effective in recovery. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 24, 2014 Category: Consumer Health News Tags: Pediatrics News Source Type: news
TPR Podcast Episode #3: Kaboom! – Exploding Toxicology
Episode 3 kaboom v2Episode 3: Kaboom! – Exploding Tox
Written by Theresa Kim
Outline
1) “Wax” or “dab”
2) Meth lab explosions
3) Smoking stool syndrome
4) Ingestion of fireworks
5) Nitropatch
6) Bonus topic related to the prior discussion of Hunan hand and food related tox
Wax or Dab
A nearly pure form of THC called “wax” or “dab” can be extracted from marijuana using a volatile hydrocarbon solvent (usually butane)
Name derived from the wax-like quality of the final product
Numerous reports of explosions at home “wax” labs
Legal in Colorad...
Source: The Poison Review - March 24, 2014 Category: Toxicology Authors: LeonThe Poison Review Tags: Podcast Source Type: news
New Pradaxa Lawsuit on Wrongful Death: Now, AttorneyOne Can Provide...
A new lawsuit was filed on March 19, by a widow in Pennsylvania Eastern District Court alleging that her husband died from renal failure and intracerebral hemorrhage caused by Pradaxa. In light of...(PRWeb March 21, 2014)Read the full story at http://www.prweb.com/releases/2014/03/prweb11694663.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - March 22, 2014 Category: Pharmaceuticals Source Type: news
Hemodialysis Adequacy and Sexual Dysfunction in CRFHemodialysis Adequacy and Sexual Dysfunction in CRF
This study investigates the issue in women with chronic renal failure. BMC Urology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 18, 2014 Category: Consumer Health News Tags: Nephrology Journal Article Source Type: news
Right bundle branch block: an uncommon cardiotoxic manifestation of hair dye poisoning-a case report - Balasubramanian D, Subramanian S, Thangaraju P, Shanmugam K.
Hair dye poisoning has been rising in incidence in the recent years. Apart from the commoner manifestations of upper airway edema, rhabdomyolysis and acute renal failure, cardiac toxicity, convulsions and sudden cardiac death are relatively rare complicati... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - March 15, 2014 Category: Global & Universal Tags: Poisoning Source Type: news
Enzyme Kinetics, Inhibition, and Regioselectivity of Aldehyde Oxidase
The aldehyde oxidase (AO) enzyme family plays an increasing role in drug development. However, a number of compounds that are AO substrates have failed in the clinic because the clearance or toxicity is underestimated by preclinical species. Human AO is much more active than rodent AO, and dogs do not have functional AO. While AOs normally make non-reactive metabolites such as lactams, the metabolic products often have much lower solubility that can lead to renal failure. While an endogenous substrate for the oxidation reaction is not known, electron acceptors for the reductive part of the reaction include oxygen and nitri...
Source: Springer protocols feed by Pharmacology/Toxicology - February 14, 2014 Category: Drugs & Pharmacology Source Type: news
6 Pearls About Metformin and Lactic Acidosis
3.5 out of 5 stars
Metformin accumulation: Lactic acidosis and high plasmatic metformin levels in a retrospective case series of 66 patients on chronic therapy. Vecchio S et al. Clin Toxicol 2014 Feb;52:129-135.
Abstract
Metformin is frequently used alone or in combination to treat type 2 diabetes. It lowers blood glucose by decreasing hepatic gluconeogenesis, predominantly by inhibiting mitochondrial respiratory chain complex I. The drug is eliminated mainly by the kidneys, and acute or chronic renal insufficiency may allow accumulation of the drug with increasing levels.
A small percentage of patients on metformin devel...
Source: The Poison Review - February 13, 2014 Category: Toxicology Authors: Leon Tags: Medical glucophage lactic acidosis MALA metabolic acidosis metformin Source Type: news
How Is Uremic Pruritus Treated?How Is Uremic Pruritus Treated?
What is the latest on managing this frequent complication of renal failure? Medscape Pharmacists (Source: Medscape Pharmacist Headlines)
Source: Medscape Pharmacist Headlines - February 12, 2014 Category: Drugs & Pharmacology Tags: Nephrology Ask the Expert Source Type: news
Martin Barratt obituary
Paediatric nephrologist whose research led to the improved treatment of common childhood kidney diseasesMartin Barratt, who has died aged 77 from a progressive form of muscular dystrophy, was professor of paediatric nephrology at the Institute of Child Health, London, and consultant nephrologist at Great Ormond Street Hospital for Children. He was one of the first to establish a specialist service for children with kidney diseases in Britain, developing a model of interdisciplinary care that was later adopted by many other centres throughout the world. His research led to improved understanding and treatment of many common...
Source: Guardian Unlimited Science - February 3, 2014 Category: Science Authors: Michael Levin Tags: theguardian.com Children Obituaries Medical research Hospitals NHS Science Source Type: news
Haemolytic uremic syndrome following fire ant bites - Lee YC, Wang JS, Shiang JC, Tsai MK, Deng KT, Chang MY, Wang HH, Ho LC, Chen YT, Hung SY.
BACKGROUND: Haemolytic-uremic syndrome (HUS) is a severe, life-threatening disease with symptoms such as haemolytic anaemia, renal failure, and a low platelet count. Possible aetiology includes bacterial infections, medication, post-hematopoietic cell tran... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - January 24, 2014 Category: Global & Universal Tags: Non-Human Animals and Insects Source Type: news
Emergency department visits in Colorado associated with smoking synthetic cannabinoids
3 out of 5 stars
Severe Illness Associated with Reported Use of Synthetic Marijuana — Colorado, August-September 2013. MMWR 2013 Dec 13;62:1016-1017.
Full Text
In August and September of this year, it became apparent to the Colorado Department of Public Health and Environment (CDPHE) that there was a significant increase in the number of patients visiting emergency departments after smoking synthetic marijuana products. Therefore, the Department sent out a request to all EDs in the state to report patients seen on or after August 21 with altered mental status after using any form of synthetic marijuana.
To study this pr...
Source: The Poison Review - December 13, 2013 Category: Toxicology Authors: Leon Tags: Medical colorado crazy clown denver spice synthetic cannabinoid Source Type: news
Acute Kidney Injury With TDF and NSAID Co-administrationAcute Kidney Injury With TDF and NSAID Co-administration
What is the frequency of acute renal failure in HIV-infected patients after co-administration of tenofovir and NSAIDs? HIV Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 2, 2013 Category: Consumer Health News Tags: HIV/AIDS Journal Article Source Type: news
TAVI Better Than Surgery for Diabetics (CME/CE)
(MedPage Today) -- Diabetic patients whose aortic stenosis was treated with transcatheter aortic valve implantation rather than surgery had lower risks of mortality and renal failure in the first year after treatment, a researchers reported. (Source: MedPage Today State Required CME)
Source: MedPage Today State Required CME - December 1, 2013 Category: Consumer Health News Source Type: news
Campbell’s Soup, American Heart Association Accused Of Misleading Customers
function cbs_video_wnplayer_9536378_start() {
var WNVideoCanvas_vid9536378 = new WNVideoWidget("WNVideoCanvas", "WNVideoCanvas_vid9536378", "1");
//Playback options
WNVideoCanvas_vid9536378.SetVariable("widgetId", 9536378);
WNVideoCanvas_vid9536378.SetVariable("addThisDivId", "WNVideoCanvas_vid9536378_addThis");
WNVideoCanvas_vid9536378.SetVariable("incanvasAdDivId", "WNVideoCanvas_vid9536378_adDiv");
WNVideoCanvas_vid9536378.SetVariable("clipId", "9536378");
// Controls options
WNVideoCanvas_vid9536378.SetVariable("isMute", "false");
WNVideoCanvas_vid9536378.SetVariable("isAutoStart", "false");
WNVid...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - November 16, 2013 Category: Consumer Health News Authors: deanreddington Tags: Health Local News Seen On WBZ-TV Syndicated Local Watch Listen Adam Levitt American Heart Association Campbell's Soup Dr. William Weintraub Joan Salge Blake Paula Ebben Sodium Source Type: news
