Pantoprazole
(Source: Reactions Weekly)
Source: Reactions Weekly - February 1, 2024 Category: Drugs & Pharmacology Source Type: research
Pantoprazole and Vonoprazan Performed Well in Preventing Peptic Ulcer Recurrence in Low-Dose Aspirin Users
ConclusionsFor patients with a history of PU receiving LDA, pantoprazole and vonoprazan might be the optimal choices to prevent PU recurrence and GI hemorrhage.Graphical Abstract (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - January 22, 2024 Category: Gastroenterology Source Type: research
Correction to: Up-regulation of autophagy is a mechanism of resistance to chemotherapy and can be inhibited by pantoprazole to increase drug sensitivity
(Source: Cancer Chemotherapy and Pharmacology)
Source: Cancer Chemotherapy and Pharmacology - January 19, 2024 Category: Cancer & Oncology Source Type: research
In vitro interactions of proton pump inhibitors and azoles against pathogenic fungi
DiscussionThe results suggested that PPIs combined with azoles has the potential to enhance the susceptibilities of azoles against multiple pathogenic fungi and could be a promising strategy to overcome azole resistance issues. However, further investigations are warranted to study the combinational efficacy in more isolates and more species, to investigate the underlying mechanism of interaction and to evaluate the potential for concomitant use of these agents in human. (Source: Frontiers in cellular and infection microbiology)
Source: Frontiers in cellular and infection microbiology - January 17, 2024 Category: Microbiology Source Type: research
Trend analysis of proton pump inhibitor consumption and expenditure: The real-world evidence
ConclusionWithin this analysis, we provide an illustrative representation of the prescribing trends for PPIs within a European context. Omeprazole, rabeprazole and lansoprazole appear to be the cheapest drugs compared to pantoprazole and esomeprazole. However, the results show that the most widely used PPIs, despite their therapeutic equivalence, are precisely the high-cost ones, thus generating higher expenditure for central governments.Graphical Abstract (Source: Indian Journal of Gastroenterology)
Source: Indian Journal of Gastroenterology - January 17, 2024 Category: Gastroenterology Source Type: research
A Retrospective Study Comparing the Effect of Conventional Coagulation Parameters Vs. Thromboelastography-Guided Blood Product Utilization in Patients With Major Gastrointestinal Bleeding
CONCLUSION: This study revealed that TEG is not superior to conventional coagulation parameters in limiting the volume of blood product transfusion in major GIB patients in ICU settings.PMID:38189039 | PMC:PMC10769601 | DOI:10.14740/jocmr5022 (Source: Clin Med Res)
Source: Clin Med Res - January 8, 2024 Category: Research Authors: Chhabindra Nepal Ojbindra Kc Manisha Koirala Ananta Subedi Rakshya Sharma Srinadh Annangi Suha Jabak Said Chaaban Source Type: research
A Retrospective Study Comparing the Effect of Conventional Coagulation Parameters Vs. Thromboelastography-Guided Blood Product Utilization in Patients With Major Gastrointestinal Bleeding
CONCLUSION: This study revealed that TEG is not superior to conventional coagulation parameters in limiting the volume of blood product transfusion in major GIB patients in ICU settings.PMID:38189039 | PMC:PMC10769601 | DOI:10.14740/jocmr5022 (Source: Clin Med Res)
Source: Clin Med Res - January 8, 2024 Category: Research Authors: Chhabindra Nepal Ojbindra Kc Manisha Koirala Ananta Subedi Rakshya Sharma Srinadh Annangi Suha Jabak Said Chaaban Source Type: research
A Retrospective Study Comparing the Effect of Conventional Coagulation Parameters Vs. Thromboelastography-Guided Blood Product Utilization in Patients With Major Gastrointestinal Bleeding
CONCLUSION: This study revealed that TEG is not superior to conventional coagulation parameters in limiting the volume of blood product transfusion in major GIB patients in ICU settings.PMID:38189039 | PMC:PMC10769601 | DOI:10.14740/jocmr5022 (Source: Clin Med Res)
Source: Clin Med Res - January 8, 2024 Category: Research Authors: Chhabindra Nepal Ojbindra Kc Manisha Koirala Ananta Subedi Rakshya Sharma Srinadh Annangi Suha Jabak Said Chaaban Source Type: research
Organ-specific immune-mediated reactions to polyethylene glycol and polysorbate excipients: three case reports
In this report, we present 3 cases of drug-related AP, AIN and DILI. The first case involved a patient with AP to lacosamide and to the excipient polysorbate 80 in pantoprazole. The second case involved a patient with DILI secondary to polyethylene glycol (PEG) excipients and amoxicillin-clavulanate. In case 3, AIN was considered to be the result of sensitization to excipients. Diagnoses were made using causality algorithms and the LTT. The LTT is a useful tool for helping diagnose drug-related AP and DILI, and it can be used to identify the specific drug or excipient causing the ADR. These cases highlight the importance o...
Source: Frontiers in Pharmacology - January 3, 2024 Category: Drugs & Pharmacology Source Type: research
Pantoprazole
(Source: Reactions Weekly)
Source: Reactions Weekly - January 1, 2024 Category: Drugs & Pharmacology Source Type: research
