Oxygen desaturation in a transgender man: initial concerns and recommendations regarding the practice of chest binding: a case report
ConclusionIn the clinical narrative, a healthy patient was observed to have prolonged oxygen desaturation after induction of anesthesia. Laryngospasm was suspected clinically owing to the sudden absence of end-tidal carbon dioxide. Prolonged oxygen desaturation despite appropriate interventions suggests the contribution of additional factors. We speculate that the presence of a chest binder intraoperatively predisposed the patient to more rapid oxygen desaturation less responsive to typical therapy. A chest binder would introduce mechanical restriction to the patient ’s breathing owing to its inherent design to compress....
Source: Journal of Medical Case Reports - September 4, 2022 Category: General Medicine Source Type: research

71-Year-Old Man With a New Heart Murmur
A 71-year-old man with a history of hypertension, hyperlipidemia, and bicuspid aortic valve endocarditis treated with prosthetic valve replacement in 2012 presented to the internal medicine clinic for his annual physical examination. His home medications included aspirin (81 mg), pantoprazole (40 mg), paroxetine (37.5 mg), rosuvastatin (20 mg), and terazosin (10 mg) daily. Review of systems was notable for increasing exertional and supine shortness of breath. He also reported occasional chest discomfort on the right side with and without exertion. (Source: Mayo Clinic Proceedings)
Source: Mayo Clinic Proceedings - September 1, 2022 Category: Internal Medicine Authors: Zeynep I. Seckin, Goyal Umadat, Richard O. White Tags: Residents ’ clinic Source Type: research

Correction to: Hepatitis C viral clearance with coadministration of crushed sofosbuvir/velpatasvir and high-dose pantoprazole after liver transplantation
Am J Health Syst Pharm. 2022 Aug 30:zxac220. doi: 10.1093/ajhp/zxac220. Online ahead of print.NO ABSTRACTPMID:36039904 | DOI:10.1093/ajhp/zxac220 (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - August 30, 2022 Category: Drugs & Pharmacology Source Type: research

Correction to: Hepatitis C viral clearance with coadministration of crushed sofosbuvir/velpatasvir and high-dose pantoprazole after liver transplantation
Am J Health Syst Pharm. 2022 Aug 30:zxac220. doi: 10.1093/ajhp/zxac220. Online ahead of print.NO ABSTRACTPMID:36039904 | DOI:10.1093/ajhp/zxac220 (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - August 30, 2022 Category: Drugs & Pharmacology Source Type: research

Impact of insufficient doses of medications on < em > Helicobacter pylori < /em > eradication: a retrospective observational study
CONCLUSION: Among the BQT regimens, PPIs and/or antibiotics, especially pantoprazole and metronidazole, are often prescribed at insufficient doses, compromising the success of H. pylori eradication.PMID:35860966 | DOI:10.1080/00325481.2022.2105094 (Source: Postgraduate Medicine)
Source: Postgraduate Medicine - July 21, 2022 Category: Internal Medicine Authors: Xiaoye Shi Chunmei Wang Fanjun Meng Shaoze Ma Guangqin Xu Tingwei Liu Xiaozhong Guo Hongyu Li Xingshun Qi Source Type: research

IJERPH, Vol. 19, Pages 8739: Dose-Dependent Proton Pump Inhibitor Exposure and Risk of Type 2 Diabetes: A Nationwide Nested Case & ndash;Control Study
Conclusions: A dose-dependent increased risk of T2DM was found among patients with UGID using higher doses of PPIs compared with those with lower doses of these drugs. Further studies are necessary to investigate the underlying pathophysiology of PPIs and T2DM. (Source: International Journal of Environmental Research and Public Health)
Source: International Journal of Environmental Research and Public Health - July 18, 2022 Category: Environmental Health Authors: Hsin-Ya Kuo Chih-Sung Liang Shih-Jen Tsai Tzeng-Ji Chen Che-Sheng Chu Mu-Hong Chen Tags: Article Source Type: research

Esophagitis after Clozapine Use in a 61-Year-Old Woman with Refractory Schizophrenia
We report here an unusual association of severe esophagitis with clozapine use.PMID:35693728 | PMC:PMC9187460 | DOI:10.1155/2022/7033038 (Source: Case Reports in Psychiatry)
Source: Case Reports in Psychiatry - June 13, 2022 Category: Psychiatry Authors: Sung Min Ma Junghyun Lim Chunsu Jiang Luminita Luca Source Type: research