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PaSTe. Blockade of the Lipid Phenotype of Prostate Cancer as Metabolic Therapy: A Theoretical Proposal
CONCLUSION: We conclude that this regimen deserves to be preclinically evaluated because of its clinical potential for the treatment of prostate cancer.PMID:37287286 | DOI:10.2174/0929867330666230607104441 (Source: Current Medicinal Chemistry)
Source: Current Medicinal Chemistry - June 8, 2023 Category: Chemistry Authors: Adriana Romo-Perez Guadalupe Dom ínguez-Gómez Alma Ch ávez-Blanco Aurora Gonz ález-Fierro Jos é Correa-Basurto Alfonso Due ñas-González Source Type: research

The impact of CYP2C19 genotype on phenoconversion by concomitant medication
Conclusion: This study suggests that the differential outcome of CYP2C19-mediated DDIs between genotypes are primarily dictated by basal CYP2C19 activity, that may in part be predicted by CYP2C19 genotype but likely also depends on disease-related factors. (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - June 8, 2023 Category: Drugs & Pharmacology Source Type: research

Avoiding incompatible drug pairs in central-venous catheters of patients receiving critical care: an algorithm-based analysis and a staff survey
ConclusionsAlthough incompatibilities were common, the staff rarely felt unsafe when administering drugs. Knowledge deficits correlated well with the incompatibilities identified. All recommendations were fully accepted. (Source: European Journal of Clinical Pharmacology)
Source: European Journal of Clinical Pharmacology - June 7, 2023 Category: Drugs & Pharmacology Source Type: research