The impact of CYP2C19 genotype on phenoconversion by concomitant medication

Conclusion: This study suggests that the differential outcome of CYP2C19-mediated DDIs between genotypes are primarily dictated by basal CYP2C19 activity, that may in part be predicted by CYP2C19 genotype but likely also depends on disease-related factors.
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research