The role of kaempferol in gynaecological malignancies: progress and perspectives
Kaempferol, a flavonoid derived from various herbs such as cocoyam, propolis, and grapefruit, has garnered interest due to its numerous pharmacological benefits, including anti-inflammatory, antioxidant, and anti-diabetic properties. Kaempferol has been shown to possess notable anti-tumour bioactivity, indicating potential for treating gynaecological malignancies. To date, numerous studies have demonstrated the potential of kaempferol to induce tumour cell apoptosis, inhibit proliferation, and prevent metastasis and invasion in several gynaecological malignancies, including breast, ovarian and endometrial cancers. However,...
Source: Frontiers in Pharmacology - December 4, 2023 Category: Drugs & Pharmacology Source Type: research
Effects of microcapsules with turmeric and green propolis supplementation on inflammatory markers in hemodialysis patients
This study aimed to evaluate the effects of microcapsules with turmeric and propolis supplementation on inflammatory markers in patients with CKD undergoing hemodialysis (HD). (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - December 1, 2023 Category: Nutrition Authors: I.K. Britto, L.F. Cardozo, H. Couto, B.R. de Paiva, J.S. de Brito, K.T. Teixeira, L. Alvarenga, T.R. Chermut, P.E.C. Leite, V.P. Delgado, A.A. Berretta, M. Ribeiro-Alves, M. Ribeiro, D. Mafra Source Type: research
Efficacy of Bee Products (Anzer Honey, Pollen and Propolis) in Detection and Healing of Damage Induced by Antidiabetic Drug Vildagliptin/Metformin Hydrochloride in Healthy Human Pancreatic Cells: Cytotoxic, Genotoxic and Biochemical Studies
ConclusionThis study can contribute to other studies testing the healing properties of natural products against the side effects of oral antidiabetics in human cells. In particular, Anzer honey, pollen and propolis can be used as additional foods to maintain cell viability and improve heal damage and can be evaluated against side effects in other drug studies. (Source: Journal of Huazhong University of Science and Technology -- Medical Sciences --)
Source: Journal of Huazhong University of Science and Technology -- Medical Sciences -- - December 1, 2023 Category: Research Source Type: research
Molecules, Vol. 28, Pages 7812: Anti-Trypanosoma cruzi Potential of Vestitol Isolated from Lyophilized Red Propolis
ta Marcolan Valverde
Saulo Fehelberg Pinto Braga
Paula Melo de Abreu Vieira
Viviane Martins Rebello dos Santos
Chagas disease (CD) is a worldwide public health problem, and the drugs available for its treatment have severe limitations. Red propolis is a natural extract known for its high content of phenolic compounds and for having activity against T. cruzi. The aim of this study was to investigate the trypanocidal potential of red propolis to isolate, identify, and indicate the mode of action of the bioactive compounds. The results revealed that the total phenolic content was 15.4 mg GAE/g, and flavonoids were 7...
Source: Molecules - November 28, 2023 Category: Chemistry Authors: Lucas Resende Dutra Sousa Tatiane Roquete Amparo Gustavo Henrique Bianco de Souza Aline Tonhela Ferraz K átia da Silva Fonseca Amanda Scofield de Azevedo Andr éa Mendes do Nascimento Ângela Leão Andrade Jana ína Brandão Seibert Thalita Marcolan Valv Tags: Article Source Type: research
The influence of propolis plus Hyoscyamus niger L. against COVID-19: A phase II, multicenter, placebo-controlled, randomized trial
Phytother Res. 2023 Nov 22. doi: 10.1002/ptr.8047. Online ahead of print.ABSTRACTThe incubation period of COVID-19 symptoms, along with the proliferation and high transmission rate of the SARS-CoV-2 virus, is the cause of an uncontrolled epidemic worldwide. Vaccination is the front line of prevention, and antiinflammatory and antiviral drugs are the treatment of this disease. In addition, some herbal therapy approaches can be a good way to deal with this disease. The aim of this study was to evaluate the effect of propolis syrup with Hyoscyamus niger L. extract in hospitalized patients with COVID-19 with acute disease cond...
Source: Cell Research - November 22, 2023 Category: Cytology Authors: Morteza Kosari Farzin Khorvash Mohammad Kazem Sayyah Maryam Ansari Chaharsoughi Ahmad Najafi Mansooreh Momen-Heravi Mohammad Karimian Hossein Akbari Mehdi Noureddini Mahmoud Salami Amir Ghaderi Javad Amini Mahabadi Seyed Peyman Khamechi Somayeh Yeganeh Ha Source Type: research
Histologic evaluation of vital pulp therapy using propolis and platelet-rich plasma (PRP): Evidence from a canine model
Conclusions: The findings suggest that propolis might be a favorable substitute for MTA in DPC procedures, as it produced comparable results to MTA in reducing inflammation and enhancing calcification. (Source: Journal of Dental Materials and Techniques)
Source: Journal of Dental Materials and Techniques - November 21, 2023 Category: Dentistry Source Type: research
Floral visitation, phytochemical and biological activities of bioproducts from Tetragonisca angustula (Hymenoptera, Apidae, Meliponini): a review
Chem Biodivers. 2023 Nov 20:e202301451. doi: 10.1002/cbdv.202301451. Online ahead of print.ABSTRACTTetragonisca angustula (Latreille, 1811) is an indigenous neotropical stingless bee, popularly known as "Jataí", with a wide distribution in the Brazilian territory. T. angustula produces other derivatives such as propolis, geopropolis, fermented (saburá pollen), cerumen and resins, which are important in folk medicine. In this review, the objective was to gather research on the main plant species visited by T. angustula, as well as studies that verified the chemical composition and biological properties of T. angustula bio...
Source: Chemistry and Biodiversity - November 20, 2023 Category: Biochemistry Authors: Nair Silva Mac êdo Zildene de Sousa Silveira Ângella Eduarda da Silva Sousa D ébora Menezes Dantas Amanda Lins Bispo Monteiro Helcio Silva Dos Santos Francisco Assis Bezerra da Cunha Source Type: research
Floral visitation, phytochemical and biological activities of bioproducts from Tetragonisca angustula (Hymenoptera, Apidae, Meliponini): a review
Chem Biodivers. 2023 Nov 20:e202301451. doi: 10.1002/cbdv.202301451. Online ahead of print.ABSTRACTTetragonisca angustula (Latreille, 1811) is an indigenous neotropical stingless bee, popularly known as "Jataí", with a wide distribution in the Brazilian territory. T. angustula produces other derivatives such as propolis, geopropolis, fermented (saburá pollen), cerumen and resins, which are important in folk medicine. In this review, the objective was to gather research on the main plant species visited by T. angustula, as well as studies that verified the chemical composition and biological properties of T. angustula bio...
Source: Chemistry and Biodiversity - November 20, 2023 Category: Biochemistry Authors: Nair Silva Mac êdo Zildene de Sousa Silveira Ângella Eduarda da Silva Sousa D ébora Menezes Dantas Amanda Lins Bispo Monteiro Helcio Silva Dos Santos Francisco Assis Bezerra da Cunha Source Type: research
Starch nanoparticles containing phenolic compounds from green propolis: Characterization and evaluation of antioxidant, antimicrobial and digestibility properties
This study investigated the production of nanoparticles through nanoprecipitation using cassava and potato starches as carriers to stabilize phenolic compounds (PC) from green propolis extract (PE). Additionally, the antioxidant and antimicrobial activities of PC stabilized with starch nanoparticles (SNPs), as well as their release under gastrointestinal conditions were investigated. PE exhibited antioxidant and antibacterial properties, especially PE3 (PE produced using sonication by 20 min and stirring at 30 °C for 24 h) had the highest concentrations of p-coumaric acid, rutin, kaempferol and quercetin. SNPs displayed b...
Source: International Journal of Biological Macromolecules - November 17, 2023 Category: Biochemistry Authors: Maria Ja ízia Dos Santos Alves Matheus Henrique Oliveira de Sousa Neusa Fernandes de Moura Karina Cesca Silvani Verruck Alcilene Rodrigues Monteiro Germ án Ayala Valencia Source Type: research
