Electrospinning-netting of spider-inspired polycaprolactone/collagen nanofiber-nets incorporated with Propolis extract for enhanced wound healing applications
In this study, a composite of polycaprolactone/collagen (PCLC) nano-fiber/nets (NFNs) was fabricated using benign solvents (acetic acid and formic acid) via the electro-spinning/netting (ESN) technique, harnessing the regenerative potential of collagen as a biological macromolecule. Additionally, to enhance the natural attributes of the NFNs structure, Propolis extract, renowned for its wound healing properties, was incorporated. Five ESN solutions were prepared: PCL, PCLC, PCLC/Pro 5 %, PCLC/Pro 10 %, and PCLC/Pro 15 %. NaCl salt was introduced into all ESN solutions to improve nanonets formation. FE-SEM imaging demonstra...
Source: International Journal of Biological Macromolecules - April 9, 2024 Category: Biochemistry Authors: Seyed Mohammad Doodmani Afsaneh Bagheri Ozra Natouri Abbas Nobakht Solmaz Saghebasl Source Type: research
Exploring the antibiofilm effects on < em > Escherichia coli < /em > biofilm associated with colon cancer and anticancer activities on HCT116 cell line of bee products
Biofouling. 2024 Apr 7:1-10. doi: 10.1080/08927014.2024.2338106. Online ahead of print.ABSTRACTThe association between dysbiotic microbiota biofilm and colon cancer has recently begun to attract attention. In the study, the apitherapeutic effects of bee products (honey, bee venom, royal jelly, pollen, perga and propolis) obtained from the endemic Yığılca ecotype of Apis mellifera anatoliaca were investigated. Antibiofilm activity were performed by microplate assay using crystal violet staining to measure adherent biofilm biomass of Escherichia coli capable of forming biofilms. Bee venom showed the highest inhibition eff...
Source: Biofouling - April 8, 2024 Category: Molecular Biology Authors: Ay şegül Akkoyunlu G örkem Dülger Source Type: research
Exploring the antibiofilm effects on < em > Escherichia coli < /em > biofilm associated with colon cancer and anticancer activities on HCT116 cell line of bee products
Biofouling. 2024 Apr 7:1-10. doi: 10.1080/08927014.2024.2338106. Online ahead of print.ABSTRACTThe association between dysbiotic microbiota biofilm and colon cancer has recently begun to attract attention. In the study, the apitherapeutic effects of bee products (honey, bee venom, royal jelly, pollen, perga and propolis) obtained from the endemic Yığılca ecotype of Apis mellifera anatoliaca were investigated. Antibiofilm activity were performed by microplate assay using crystal violet staining to measure adherent biofilm biomass of Escherichia coli capable of forming biofilms. Bee venom showed the highest inhibition eff...
Source: Biofouling - April 8, 2024 Category: Molecular Biology Authors: Ay şegül Akkoyunlu G örkem Dülger Source Type: research
Exploring the antibiofilm effects on < em > Escherichia coli < /em > biofilm associated with colon cancer and anticancer activities on HCT116 cell line of bee products
Biofouling. 2024 Apr 7:1-10. doi: 10.1080/08927014.2024.2338106. Online ahead of print.ABSTRACTThe association between dysbiotic microbiota biofilm and colon cancer has recently begun to attract attention. In the study, the apitherapeutic effects of bee products (honey, bee venom, royal jelly, pollen, perga and propolis) obtained from the endemic Yığılca ecotype of Apis mellifera anatoliaca were investigated. Antibiofilm activity were performed by microplate assay using crystal violet staining to measure adherent biofilm biomass of Escherichia coli capable of forming biofilms. Bee venom showed the highest inhibition eff...
Source: Biofouling - April 8, 2024 Category: Molecular Biology Authors: Ay şegül Akkoyunlu G örkem Dülger Source Type: research
Exploring the antibiofilm effects on < em > Escherichia coli < /em > biofilm associated with colon cancer and anticancer activities on HCT116 cell line of bee products
Biofouling. 2024 Apr 7:1-10. doi: 10.1080/08927014.2024.2338106. Online ahead of print.ABSTRACTThe association between dysbiotic microbiota biofilm and colon cancer has recently begun to attract attention. In the study, the apitherapeutic effects of bee products (honey, bee venom, royal jelly, pollen, perga and propolis) obtained from the endemic Yığılca ecotype of Apis mellifera anatoliaca were investigated. Antibiofilm activity were performed by microplate assay using crystal violet staining to measure adherent biofilm biomass of Escherichia coli capable of forming biofilms. Bee venom showed the highest inhibition eff...
Source: Biofouling - April 8, 2024 Category: Molecular Biology Authors: Ay şegül Akkoyunlu G örkem Dülger Source Type: research
Exploring the antibiofilm effects on < em > Escherichia coli < /em > biofilm associated with colon cancer and anticancer activities on HCT116 cell line of bee products
Biofouling. 2024 Apr 7:1-10. doi: 10.1080/08927014.2024.2338106. Online ahead of print.ABSTRACTThe association between dysbiotic microbiota biofilm and colon cancer has recently begun to attract attention. In the study, the apitherapeutic effects of bee products (honey, bee venom, royal jelly, pollen, perga and propolis) obtained from the endemic Yığılca ecotype of Apis mellifera anatoliaca were investigated. Antibiofilm activity were performed by microplate assay using crystal violet staining to measure adherent biofilm biomass of Escherichia coli capable of forming biofilms. Bee venom showed the highest inhibition eff...
Source: Biofouling - April 8, 2024 Category: Molecular Biology Authors: Ay şegül Akkoyunlu G örkem Dülger Source Type: research
Exploring the antibiofilm effects on < em > Escherichia coli < /em > biofilm associated with colon cancer and anticancer activities on HCT116 cell line of bee products
Biofouling. 2024 Apr 7:1-10. doi: 10.1080/08927014.2024.2338106. Online ahead of print.ABSTRACTThe association between dysbiotic microbiota biofilm and colon cancer has recently begun to attract attention. In the study, the apitherapeutic effects of bee products (honey, bee venom, royal jelly, pollen, perga and propolis) obtained from the endemic Yığılca ecotype of Apis mellifera anatoliaca were investigated. Antibiofilm activity were performed by microplate assay using crystal violet staining to measure adherent biofilm biomass of Escherichia coli capable of forming biofilms. Bee venom showed the highest inhibition eff...
Source: Biofouling - April 8, 2024 Category: Molecular Biology Authors: Ay şegül Akkoyunlu G örkem Dülger Source Type: research
Exploring the antibiofilm effects on < em > Escherichia coli < /em > biofilm associated with colon cancer and anticancer activities on HCT116 cell line of bee products
Biofouling. 2024 Apr 7:1-10. doi: 10.1080/08927014.2024.2338106. Online ahead of print.ABSTRACTThe association between dysbiotic microbiota biofilm and colon cancer has recently begun to attract attention. In the study, the apitherapeutic effects of bee products (honey, bee venom, royal jelly, pollen, perga and propolis) obtained from the endemic Yığılca ecotype of Apis mellifera anatoliaca were investigated. Antibiofilm activity were performed by microplate assay using crystal violet staining to measure adherent biofilm biomass of Escherichia coli capable of forming biofilms. Bee venom showed the highest inhibition eff...
Source: Biofouling - April 8, 2024 Category: Molecular Biology Authors: Ay şegül Akkoyunlu G örkem Dülger Source Type: research
Preventive effect of propolis on cognitive decline in Alzheimer's disease model mice
Neurobiol Aging. 2024 Mar 13;139:20-29. doi: 10.1016/j.neurobiolaging.2024.03.002. Online ahead of print.ABSTRACTBrazilian green propolis (propolis) is a chemically complex resinous substance that is a potentially viable therapeutic agent for Alzheimer's disease. Herein, propolis induced a transient increase in intracellular Ca2+ concentration ([Ca2+]i) in Neuro-2A cells; moreover, propolis-induced [Ca2+]i elevations were suppressed prior to 24-h pretreatment with amyloid-β. To reveal the effect of [Ca2+]i elevation on impaired cognition, we performed memory-related behavioral tasks in APP-KI mice relative to WT mice at 4...
Source: Neurobiology of Aging - April 7, 2024 Category: Geriatrics Authors: Ryo Inagaki Tohru Yamakuni Takashi Saito Takaomi C Saido Shigeki Moriguchi Source Type: research
Phytochemical Profile, Antioxidant, Enzyme Inhibition, Acute Toxicity, In Silico Molecular Docking and Dynamic Analysis of Apis mellifera Propolis as Antidiabetic Supplement
This study aims to identification of phytochemical profile of Apis mellifera propolis and explore potential of its anti-diabetic activity through inhibition on α-amylase (α-AE), α-glucosidase(α-GE) and finally identified the novel antidiabetic compounds from propolis. Apis mellifera propolis extract (AMPE) exhibited elevated polyphenol 33.26 ± 0.17 (mg GAE/g) and flavonoid (15.45 ± 0.13 mg RE/g), while its also indicated moderate strong antioxidant activity (EC50 793.09 ±1.94 µg/ml). This study found that AMPE displayed promising α-AE and α-GE inhibition through in vitro study. Based on LC-MS/MS screening, 18 uni...
Source: Chemistry and Biodiversity - April 7, 2024 Category: Biochemistry Authors: Putri Hawa Syaifie Delfritama Ibadillah Muhammad Miftah Jauhar Rikania Reninta Sri Ningsih Donny Ramadhan Adzani Gaisani Arda Dhecella Winy Cintya Ningrum Nofa Mardia Ningsih Kaswati Nurul Taufiqu Rochman Etik Mardliyati Source Type: research
Preventive effect of propolis on cognitive decline in Alzheimer's disease model mice
Neurobiol Aging. 2024 Mar 13;139:20-29. doi: 10.1016/j.neurobiolaging.2024.03.002. Online ahead of print.ABSTRACTBrazilian green propolis (propolis) is a chemically complex resinous substance that is a potentially viable therapeutic agent for Alzheimer's disease. Herein, propolis induced a transient increase in intracellular Ca2+ concentration ([Ca2+]i) in Neuro-2A cells; moreover, propolis-induced [Ca2+]i elevations were suppressed prior to 24-h pretreatment with amyloid-β. To reveal the effect of [Ca2+]i elevation on impaired cognition, we performed memory-related behavioral tasks in APP-KI mice relative to WT mice at 4...
Source: Neurobiology of Aging - April 7, 2024 Category: Geriatrics Authors: Ryo Inagaki Tohru Yamakuni Takashi Saito Takaomi C Saido Shigeki Moriguchi Source Type: research
Preventive effect of propolis on cognitive decline in Alzheimer's disease model mice
Neurobiol Aging. 2024 Mar 13;139:20-29. doi: 10.1016/j.neurobiolaging.2024.03.002. Online ahead of print.ABSTRACTBrazilian green propolis (propolis) is a chemically complex resinous substance that is a potentially viable therapeutic agent for Alzheimer's disease. Herein, propolis induced a transient increase in intracellular Ca2+ concentration ([Ca2+]i) in Neuro-2A cells; moreover, propolis-induced [Ca2+]i elevations were suppressed prior to 24-h pretreatment with amyloid-β. To reveal the effect of [Ca2+]i elevation on impaired cognition, we performed memory-related behavioral tasks in APP-KI mice relative to WT mice at 4...
Source: Neurobiology of Aging - April 7, 2024 Category: Geriatrics Authors: Ryo Inagaki Tohru Yamakuni Takashi Saito Takaomi C Saido Shigeki Moriguchi Source Type: research
Molecules, Vol. 29, Pages 1643: Physicochemical Characterization, Antioxidant, and Proliferative Activity of Colombian Propolis Extracts: A Comparative Study
This study aimed to analyze propolis extracts&rsquo; phytochemical, physicochemical, and biological activities from four different biogeographic zones of the Huila region (Colombia). The raw material samples were collected by the scraping method and the ethanolic extracts (EEPs) were obtained by cold maceration with ethanol (96%). The physicochemical and sensory characterization was carried out according to the protocols recommended by the Brazilian Ministry of Agriculture and the main components of the EEPs were identified by LC-HRMS analysis. The determination of total phenols and flavonoids was carried out using...
Source: Molecules - April 6, 2024 Category: Chemistry Authors: Diana Marcela Buitrago Sandra J. Perdomo Francisco Arturo Silva Willy Cely-Veloza Gloria In és Lafaurie Tags: Article Source Type: research
Comparative effectiveness of Propolis with chlorhexidine mouthwash on gingivitis – a randomized controlled clinical study
To assess and compare the effectiveness of propolis mouthwash with chlorhexidine mouthwash in the reduction of plaque and gingivitis. (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - April 6, 2024 Category: Complementary Medicine Authors: Shilpa Gunjal and Deepak Gowda Sadashivappa Pateel Tags: Research Source Type: research
Evaluation of the antinociceptive activities of natural propolis extract derived from stingless bee < em > Trigona thoracica < /em > in mice
CONCLUSIONS: : APE from Trigona thoracica, containing p-coumaric acid and caffeic acid, exhibited antinociceptive effects, which supports its potential use in targeting the prevention or reversal of central and peripheral sensitization that may produce clinical pain conditions.PMID:38557655 | DOI:10.3344/kjp.23318 (Source: Korean Journal of Pain)
Source: Korean Journal of Pain - April 1, 2024 Category: Anesthesiology Authors: Nurul Alina Muhamad Suhaini Mohd Faeiz Pauzi Siti Norazlina Juhari Noor Azlina Abu Bakar Jee Youn Moon Source Type: research
