Macamide, a component of maca (Lepidium meyenii Walp) lipophilic extract, enhances myogenic differentiation via AKT/p38 signaling and attenuates dexamethasone-induced muscle atrophy
In this study, maca roots of various colors (yellow, red, or black) were extracted using different polar solvents (PE, HEX, or BuOH) to compare their effects on muscle differentiation. Among them, the red maca lipophilic extract, which showed the most effectiveness, was chosen for further investigation. Our results show that RMLE enhances muscle differentiation by inducing MyoD-E2A heterodimerization through the activation of the AKT/p38 pathway. Additionally, RMLE attenuated dexamethasone-induced muscle atrophy by inhibiting nuclear translocation of FoxO3a and expression of E3-ligase (MAFbx and MURF1) in vitro and in vivo...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - February 10, 2024 Category: Drugs & Pharmacology Authors: Jongbeom Chae Dongyup Hahn Ju-Ock Nam Source Type: research
Seroprevalence of reproductive and infectious diseases in cattle: the case of Madre de Dios in the Peruvian southeastern tropics
The objective of this study was to determine the seroprevalence of reproductive and infectious diseases in tropical cattle in the Tambopata and Tahuamanu Provinces in the department of Madre de Dios, Peru.SAMPLE: 156 bovines from 7 cattle farms were sampled. These farms used exclusive grazing for food and natural mating for reproduction and did not have sanitary or vaccination programs.METHODS: The serum of blood samples was subjected to ELISA with commercial kits for the detection of antibodies against Neospora caninum, Mycobacterium avium subsp paratuberculosis (MAP), Leptospira interrogans, pestivirus bovine viral diarr...
Source: Herpes - February 9, 2024 Category: Infectious Diseases Authors: Silvia E Le ón Trinidad Christian Barrantes Bravo Shefferson Feijoo Narvasta Ethel Huam án Fuertes Gustavo Ampuero Trigoso Francys Canto S áenz Hurley A Quispe-Ccasa Source Type: research
Seroprevalence of reproductive and infectious diseases in cattle: the case of Madre de Dios in the Peruvian southeastern tropics
The objective of this study was to determine the seroprevalence of reproductive and infectious diseases in tropical cattle in the Tambopata and Tahuamanu Provinces in the department of Madre de Dios, Peru.SAMPLE: 156 bovines from 7 cattle farms were sampled. These farms used exclusive grazing for food and natural mating for reproduction and did not have sanitary or vaccination programs.METHODS: The serum of blood samples was subjected to ELISA with commercial kits for the detection of antibodies against Neospora caninum, Mycobacterium avium subsp paratuberculosis (MAP), Leptospira interrogans, pestivirus bovine viral diarr...
Source: American Journal of Veterinary Research - February 9, 2024 Category: Veterinary Research Authors: Silvia E Le ón Trinidad Christian Barrantes Bravo Shefferson Feijoo Narvasta Ethel Huam án Fuertes Gustavo Ampuero Trigoso Francys Canto S áenz Hurley A Quispe-Ccasa Source Type: research
Use of TikTok to improve the knowledge of Peruvian accreditation in Dentistry students
Aten Primaria. 2024 Feb 7;56(4):102812. doi: 10.1016/j.aprim.2023.102812. Online ahead of print.NO ABSTRACTPMID:38330809 | DOI:10.1016/j.aprim.2023.102812 (Source: Atencion Primaria)
Source: Atencion Primaria - February 8, 2024 Category: Primary Care Authors: Marisel Roxana Valenzuela Ramos Gustavo Canales Serme ño Pedro Miguel Dias Monteiro Dario Emiliano Medina Castro Source Type: research
'You have a lot of mirrors': structural and socioecological factors impacting adolescent pregnancy and reproductive health in the Amazon basin, Peru, a qualitative study
This study investigated adolescent reproductive health within Loreto using an ecological systems framework. Forty-one semi-structured interviews were conducted in June 2022: community leaders (n = 12) and adolescent participants between 15 and 17 years of age (pregnant girls, n = 11; never pregnant girls, n = 9; and boys, n = 9). We also conducted focus group discussions with community health workers and educators in October 2022 (three focus groups, n = 15). Adolescent reproductive health is complex with multi-layered factors that put girls at higher risk of pregnancy. We found a paradoxical relationship between expected ...
Source: Culture, Health and Sexuality - February 5, 2024 Category: International Medicine & Public Health Authors: Lisa Labita Woodson Adriana Garcia Saldivar Heidi E Brown Priscilla A Magrath Leslie V Farland Magaly M Blas Purnima Madhivanan Source Type: research
Population structure of Mycobacterium tuberculosis in El Oro: A first insight into Ecuador-Peru tuberculosis transmission
CONCLUSIONS: These results may suggest that TB dynamics in this rural and semi-urban area would not be linked to highly transmitted strains like MTBC L2-Beijing from Peru, but related to TB relapse; although further studies with larger MTBC cultures collection from recent years are needed. Nevertheless, we recommend to reinforce TB surveillance programs in remote rural settings and border regions in Ecuador.PMID:38310744 | DOI:10.1016/j.jiph.2024.01.015 (Source: Rural Remote Health)
Source: Rural Remote Health - February 4, 2024 Category: Rural Health Authors: Bernardo Castro-Rodriguez Kerly Le ón-Ordóñez Greta Franco-Sotomayor Jos é Manuel Benítez-Medina Natalia Jim énez-Pizarro Greta C árdenas-Franco Juan Carlos Granda Juan Luis Aguirre-Mart ínez Solon Alberto Orlando Javier Hermoso de Mendoza Miguel Source Type: research
On a remote Pacific island, clues to El Ni ño’s future are preserved in ancient reefs
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A new way for the heart and brain to ‘talk’ to each other, and Earth’s future weather written in ancient coral reefs
BY
Sarah Crespi
,
Kevin McLean
,
Paul Voosen
Vanuatu—
The 500 residents of Tanovusvus do not typically worry about water. The village hugs the coast of Espiritu Santo, the largest island here in Vanuatu, a tropical archipelago in the western South Pacific Ocean. The lush foliage that surroun...
Source: Science of Aging Knowledge Environment - February 1, 2024 Category: Geriatrics Source Type: research
Notes from the Field: Dengue Outbreak - Peru, 2023
MMWR Morb Mortal Wkly Rep. 2024 Feb 1;73(4):86-88. doi: 10.15585/mmwr.mm7304a4.NO ABSTRACTPMID:38300858 | PMC:PMC10843068 | DOI:10.15585/mmwr.mm7304a4 (Source: MMWR Morb Mortal Wkl...)
Source: MMWR Morb Mortal Wkl... - February 1, 2024 Category: Epidemiology Authors: C ésar V Munayco Betsabet Yadira Valderrama Rosales Susan Yanett Mateo Lizarbe Carmen Rosa Yon Fabian Ricardo Pe ña Sánchez C ésar Henry Vásquez Sánchez Maria Paquita Garc ía Carlos Padilla-Rojas Victor Su árez Liliana S ánchez-González Forrest Source Type: research
Effects of breastfeeding on children ’s gut colonization with multidrug-resistant Enterobacterales in peri-urban Lima, Peru
Volume 16, Issue 1, January-December 2024 . (Source: Gut Microbes)
Source: Gut Microbes - February 1, 2024 Category: Microbiology Authors: Maya L. NadimpalliLuismarcelo Rojas SalvatierraSubhra ChakrabortyJenna M. SwarthoutLilia Z. CabreraAmy J. PickeringMaritza CalderonMayuko SaitoRobert H. GilmanMonica J. Pajueloa Gangarosa Department of Environmental Health, Emory Rollins School of Public Source Type: research
IJERPH, Vol. 21, Pages 166: Task Sharing and Remote Delivery of Brief Interpersonal Counseling for Venezuelan Migrants and Refugees Living in Peru during the COVID-19 Pandemic: A Mixed-Methods Pilot Study
Ponce de Leon
Helen Verdeli
Refugees and migrants experience an elevated risk for mental health problems and face significant barriers to receiving services. Interpersonal counseling (IPC-3) is a three-session intervention that can be delivered by non-specialists to provide psychological support and facilitate referrals for individuals in need of specialized care. We piloted IPC-3 delivered remotely by eight Venezuelan refugee and migrant women living in Peru. These counselors provided IPC-3 to Venezuelan refugee and migrant clients in Peru (n = 32) who reported psychological distress. Clients completed assessments o...
Source: International Journal of Environmental Research and Public Health - January 31, 2024 Category: Environmental Health Authors: M. Claire Greene Mayra Muro Jeremy C. Kane Erin Young Alejandra Paniagua-Avila Lucy Miller-Suchet Maria Nouel Annie G. Bonz Maria Cristobal Matthew Schojan Peter Ventevogel Bryan Cheng Silvia S. Martins Jose Carlos Ponce de Leon Helen Verdeli Tags: Article Source Type: research
Incursion of Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Virus, Brazil, 2023
We report 4 highly pathogenic avian influenza A(H5N1) clade 2.3.4.4.b viruses in samples collected during June 2023 from Royal terns and Cabot's terns in Brazil. Phylodynamic analysis revealed viral movement from Peru to Brazil, indicating a concerning spread of this clade along the Atlantic Americas migratory bird flyway.PMID:38290826 | DOI:10.3201/eid3003.231157 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - January 30, 2024 Category: Infectious Diseases Authors: Andreina Carvalho de Ara újo Laura Morais Nascimento Silva Andrew Yong Cho M árcio Repenning Deyvid Amgarten Ana Paula de Moraes Fernanda Malta Michael Miller Erick G Dorlass Soledad Palameta Daniele Bruna L Oliveira Jansen de Ara újo Clarice Weis Arns Source Type: research
IJERPH, Vol. 21, Pages 154: Knowledge and Attitudes of Parents about Oral Health in the Primary Dentition Stage in a Peruvian High Andean City
a-López
Children’s oral health depends on parents’ knowledge and attitudes. The primary dentition stage, in particular, plays a crucial role in the comprehensive development of children. Therefore, the objective was to evaluate parents’ knowledge and attitudes about oral health in the primary dentition stage in Chachapoyas (Amazonas, NW Peru). A questionnaire was administered to 409 parents from 15 educational institutions, and the data were analyzed using multinomial logistic regression. Among the surveyed parents, 75.3% could identify at least one habit harmful to their chil...
Source: International Journal of Environmental Research and Public Health - January 30, 2024 Category: Environmental Health Authors: Nilton B. Rojas-Brice ño Oscar J. Oc Oc Carrasco Yshoner A. Silva Silva D íaz Carla M. Ordinola Ram írez Oscar Pizarro Salazar Sh írley J. Tuesta-Mendoza Jhonsy O. Silva-L ópez Tags: Article Source Type: research
Association between love breakup and suicidal ideation in Peruvian medical students: a cross-sectional study during the COVID-19 pandemic
ConclusionOur study provides evidence of a significant association between a major love breakup and suicidal ideation. This finding emphasizes the need for further research to better understand this association and inform the development of effective suicide prevention policies in medical education. (Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - January 29, 2024 Category: Psychiatry Source Type: research
Network analysis of pandemic fatigue symptoms in samples from five South American countries
CONCLUSIONS: This study is the first to provide information on how pandemic fatigue symptoms were related during the COVID-19 pandemic.PMID:38279537 | DOI:10.1177/00207640231223430 (Source: The International Journal of Social Psychiatry)
Source: The International Journal of Social Psychiatry - January 27, 2024 Category: Psychiatry Authors: Tom ás Caycho-Rodríguez Julio Torales Jos é Ventura-León Iv án Barrios Marcela Waisman-Campos Alexandra Terrazas-Landivar Laura Viola Lindsey W Vilca Agueda Mu ñoz-Del-Carpio-Toia Source Type: research
Molecular survey of hemoplasmas and Coxiella burnetii in vampire bats from northern Brazil
Comp Immunol Microbiol Infect Dis. 2024 Jan 17;106:102127. doi: 10.1016/j.cimid.2024.102127. Online ahead of print.ABSTRACTIn addition to zoonotic viral pathogens, bats can also harbor bacterial pathogens, including hemoplasmas (hemotropic mycoplasmas) and Coxiella burnetii. The present study aimed to investigate, using molecular techniques, the presence of hemoplasmas and C. burnetii in spleen samples from vampire bats in northern Brazil. For this purpose, between 2017 and 2019, spleen samples were collected from Desmodus rotundus (n = 228) and Diaemus youngii (n = 1) captured in the states of Pará (n = 207), Amazonas (n...
Source: Comparative immunology, microbiology and infectious diseases. - January 26, 2024 Category: Allergy & Immunology Authors: Vict ória Valente Califre de Mello Laryssa Borges de Oliveira Taciana Fernandes Souza Barbosa Coelho Daniel Antonio Braga Lee Eliz Oliveira Franco Rosangela Zacarias Machado Marcos Rog ério André Source Type: research
