The structures of two polysaccharides from Lepidium meyenii and their immunomodulatory effects via activating NF- κB signaling pathway
Int J Biol Macromol. 2024 Apr 23:131761. doi: 10.1016/j.ijbiomac.2024.131761. Online ahead of print.ABSTRACTLepidium meyenii Walp., also known as the "Peruvian national treasure", is a popular functional food in the daily lives of Peruvian people due to its bioactive with main polysaccharides. However, studies on polysaccharides isolated from Lepidium meyenii were few. Two new highly heterogeneous polysaccharides, MCP-1a and MCP-2b, were isolated and purified from the tuber of Lepidium meyenii. The structure characterization revealed that MCP-1a primarily consisted of D-Glc and had a molecular weight of 6.6 kDa. Its backbo...
Source: International Journal of Biological Macromolecules - April 25, 2024 Category: Biochemistry Authors: Zhou-Wei Wu Xing-Rong Peng Xiao-Cui Liu Luan Wen Xin-Yu Tao Abdulbaset Al-Romaima Ming-Yi Wu Ming-Hua Qiu Source Type: research
Sampling is decisive to determination of < i > Leishmania (Viannia) < /i > species
ConclusionsThe type of clinical sample can directly influence the detection and identification ofLeishmania (Viannia) species. Here, we demonstrated that lancet scraping samples consistently allowed the identification of more leishmaniasis cases compared to filter paper imprints or biopsies. This procedure is inexpensive, painless, and easy to implement at the point of care and avoids the need for anesthesia, surgery, and hospitalization and therefore could be used in resource limited settings for both military and civilian populations. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - April 25, 2024 Category: Tropical Medicine Authors: Maxy B. De los Santos Source Type: research
Increased Prevalence of Antibodies to Hepatitis E Virus in Patients with Neurocysticercosis
Am J Trop Med Hyg. 2024 Apr 23:tpmd230856. doi: 10.4269/ajtmh.23-0856. Online ahead of print.ABSTRACTWe explored the association between serological status for hepatitis E and neurocysticercosis (NCC) in neurologic patients attending a national neurological referral center in Lima, Perú, between the years 2008 and 2012. Anti-hepatitis E antibodies were evaluated in patients with and without NCC, and a control group of rural general population. Anti-hepatitis E IgG was found in 23.8% of patients with NCC, compared with 14.3% in subjects without NCC from a general rural population (P = 0.023) and 14.4% in subjects with neur...
Source: The American Journal of Tropical Medicine and Hygiene - April 23, 2024 Category: Tropical Medicine Authors: Jesus Abanto Arantxa N Sanchez Boluarte Yesenia Castillo Erika Perez Herbert Saavedra Isidro Gonzales Javier A Bustos Florence Abravanel Jacques Izopet Richie G Madden Hector H Garcia Harry R Dalton Source Type: research
Increased Prevalence of Antibodies to Hepatitis E Virus in Patients with Neurocysticercosis
Am J Trop Med Hyg. 2024 Apr 23:tpmd230856. doi: 10.4269/ajtmh.23-0856. Online ahead of print.ABSTRACTWe explored the association between serological status for hepatitis E and neurocysticercosis (NCC) in neurologic patients attending a national neurological referral center in Lima, Perú, between the years 2008 and 2012. Anti-hepatitis E antibodies were evaluated in patients with and without NCC, and a control group of rural general population. Anti-hepatitis E IgG was found in 23.8% of patients with NCC, compared with 14.3% in subjects without NCC from a general rural population (P = 0.023) and 14.4% in subjects with neur...
Source: Am J Trop Med Hyg - April 23, 2024 Category: Infectious Diseases Authors: Jesus Abanto Arantxa N Sanchez Boluarte Yesenia Castillo Erika Perez Herbert Saavedra Isidro Gonzales Javier A Bustos Florence Abravanel Jacques Izopet Richie G Madden Hector H Garcia Harry R Dalton Source Type: research
Effect of spatiotemporal variables on abundance, biting activity and parity of Nyssorhynchus darlingi (Diptera: Culicidae) in peri-Iquitos, Peru
In malaria endemic regions of the Peruvian Amazon, rainfall together with river level and breeding site availability drive fluctuating vector mosquito abundance and human malaria cases, leading to temporal het... (Source: Malaria Journal)
Source: Malaria Journal - April 19, 2024 Category: Infectious Diseases Authors: Sara A. Bickersmith, Marlon P. Saavedra, Catharine Prussing, Rachel E. Lange, Juliana A. Morales, Freddy Alava, Joseph M. Vinetz, Dionicia Gamboa, Marta Moreno and Jan E. Conn Tags: Research Source Type: research
Gastrointestinal bleeding due to disseminated histoplasmosis in a patient under anti-TNF treatment
Rev Esp Enferm Dig. 2024 Apr 18. doi: 10.17235/reed.2024.10432/2024. Online ahead of print.ABSTRACTA 62-year-old woman, originally from Peru, with rheumatoid arthritis under treatment with anti-tumor necrosis factor (anti-TNF) therapy, was admitted due to constitutional syndrome and suspicion of neoplasia. Computed tomography (CT) scan revealed involvement of three segments of the colon, ascites, and likely peritoneal implants. Ascitic fluid analysis showed elevated adenosine deaminase (ADA) levels and lymphocytosis. The patient presented with hematemesis and hematochezia with hemodynamic instability. Upper gastrointestina...
Source: Revista Espanola de Enfermedades Digestivas - April 18, 2024 Category: Gastroenterology Authors: Irene Gonz ález Díaz Cristina Su árez Ferrer Clara Amiama Roig Carmen Amor Costa Source Type: research
Striking Amazonian butterfly is result of ancient hybrid event
When separate species mate, it’s often an evolutionary dead end. Even if breeding succeeds, it can lead to infertile offspring, such as mules, or to the two species gradually merging into one as they interbreed over generations.
An Amazonian butterfly species represents a rare third scenario. In a study out today in
Nature
, researchers report that
Heliconius elevatus
—a red, black, and yellow butterfly found throughout the Amazon—is a genetically unique, reproductively healthy insect that
resulted from an ancient pairing of two other, still-present butterfly species
. The work con...
Source: Science of Aging Knowledge Environment - April 17, 2024 Category: Geriatrics Source Type: research
Occurrence of area postrema syndrome during follow-up: phenotype and influence over NMOSD activity in LATAM in real-world settings
ConclusionsOur findings indicate that 18.3% of NMOSD patients developed APS during the follow-up period, with most patients fulfilling criteria for severe APS. The inflammatory activity decreased after the onset of APS compared to the previous year. (Source: Journal of Neurology)
Source: Journal of Neurology - April 17, 2024 Category: Neurology Source Type: research
Study protocol: improving response to malaria in the Amazon through identification of inter-community networks and human mobility in border regions of Ecuador, Peru and Brazil
This study develops a network survey to quantify the effect of community connectivity and mobility on malaria transmission.
Methods
We measure community connectivity across the study area using a respondent driven sampling design among key informants who are at least 18 years of age. 45 initial communities will be selected: 10 in Brazil, 10 in Ecuador and 25 in Peru. Participants will be recruited in each initial node and administered a survey to obtain data on each community’s mobility patterns. Survey responses will be ranked and the 2–3 most connected communities will then be selected and surveyed. This pro...
Source: BMJ Open - April 15, 2024 Category: General Medicine Authors: Janko, M. M., Araujo, A. L., Ascencio, E. J., Guedes, G. R., Vasco, L. E., Santos, R. O., Damasceno, C. P., Medrano, P. G., Chacon-Uscamaita, P. R., Gunderson, A. K., OMalley, S., Kansara, P. H., Narvaez, M. B., Coombes, C., Pizzitutti, F., Salmon-Mulanov Tags: Open access, Global health Source Type: research
Association Between Abdominal Obesity and Depressive Symptoms in Peruvian Women Aged 18-49 Years: A Sub-analysis of the DHS 2018-2019
CONCLUSIONS: Therefore, although both conditions are common in women of this age group, no significant association was found between AO and depressive symptoms.PMID:38605643 | DOI:10.1017/S1368980024000867 (Source: Public Health Nutrition)
Source: Public Health Nutrition - April 12, 2024 Category: International Medicine & Public Health Authors: Sharon Leon-Zamora David Villarreal-Zegarra Luciana Bellido-Boza Source Type: research
Association Between Abdominal Obesity and Depressive Symptoms in Peruvian Women Aged 18-49 Years: A Sub-analysis of the DHS 2018-2019
CONCLUSIONS: Therefore, although both conditions are common in women of this age group, no significant association was found between AO and depressive symptoms.PMID:38605643 | DOI:10.1017/S1368980024000867 (Source: Public Health Nutrition)
Source: Public Health Nutrition - April 12, 2024 Category: International Medicine & Public Health Authors: Sharon Leon-Zamora David Villarreal-Zegarra Luciana Bellido-Boza Source Type: research
Cancers, Vol. 16, Pages 1476: Helicobacter pylori cagA, vacA, iceA and babA Genotypes from Peruvian Patients with Gastric Intestinal Metaplasia
This study was cross-sectional and included 158 H. pylori clinical isolates; each isolate corresponded to a different Peruvian patient, genotyped by polymerase chain reaction to detect cagA gene and EPIYA motifs, the vacA gene (alleles s1, s2, i1, i2, d1, d2, m1, m2 and subtypes s1a, s1b and s1c), the iceA gene (alleles 1 and 2), and the babA gene (allele 2). We observed that 38.6% presented with IM and that all clinical isolates were CagA positive. The EPIYA-ABC motif was predominant (68.4%), and we observed a high frequency for the vacA gene alleles s1 (94.9%), m1 (81.7%), i1 (63.9%), and d1 (70.9%). Strains with both ic...
Source: Cancers - April 12, 2024 Category: Cancer & Oncology Authors: Jes ús Guzmán Denis Castillo Anabel D. Gonz ález-Siccha Alejandro Bussalleu Alba A. Trespalacios-Rangel Andres G. Lescano Michel Sauvain Tags: Article Source Type: research
Hypertension subtypes at high altitude in Peru: Analysis of the Demographic and Family Health Survey 2016 –2019
ConclusionsResidents at high altitudes in Peru have a lower prevalence rate of ISH and a higher prevalence rate of IDH compared to those living at low altitudes. Further studies are needed to determine the influence of other biological, environmental, and healthcare access factors on this relationship. (Source: PLoS One)
Source: PLoS One - April 12, 2024 Category: Biomedical Science Authors: Brando Ortiz-Saavedra Source Type: research
