Head-to-head comparison of the diagnostic performance between 68Ga-FAPI-04 PET/CT and 18F-FDG PET/CT in colorectal cancer: a systematic review and meta-analysis
This study aimed to compare the detection rates of68Ga-FAPI-04 PET/CT and18F-FDG PET/CT in colorectal cancer. A systematic search of major medical databases was conducted to identify studies up to September 2023. The primary outcome assessed was the detection rate of68Ga-FAPI-04 PET/CT and18F-FDG PET/CT in the primary tumor. Pooled risk ratios with a 95% CI were calculated using random-effect models to adjust for heterogeneity. Eight studies were included in the meta-analysis.68Ga-FAPI-04 PET/CT has higher uptakes in lymph nodes, bone, and peritoneal metastasis compared with18F-FDG PET/CT. The detection rate of68Ga-FAPI-04...
Source: Abdominal Imaging - April 8, 2024 Category: Radiology Source Type: research

Should Cytoreductive Surgery Alone for Peritoneal Metastases of Colorectal Origin be Centralized? A National Study of 4159 Procedures
CONCLUSIONS: Centralization of CRS alone should improve patient selection as well as FTR and POM. After P7, CRS/HIPEC decreased mostly in Cancer centers, without any impact on the number of CRS-alone cases referred to expert centers.PMID:38549002 | DOI:10.1245/s10434-024-15180-5 (Source: Ann Oncol)
Source: Ann Oncol - March 29, 2024 Category: Cancer & Oncology Authors: Barbara Noiret Xavier Lenne Am élie Bruandet Guillaume Piessen Clarisse Eveno Source Type: research

Should Cytoreductive Surgery Alone for Peritoneal Metastases of Colorectal Origin be Centralized? A National Study of 4159 Procedures
CONCLUSIONS: Centralization of CRS alone should improve patient selection as well as FTR and POM. After P7, CRS/HIPEC decreased mostly in Cancer centers, without any impact on the number of CRS-alone cases referred to expert centers.PMID:38549002 | DOI:10.1245/s10434-024-15180-5 (Source: Ann Oncol)
Source: Ann Oncol - March 29, 2024 Category: Cancer & Oncology Authors: Barbara Noiret Xavier Lenne Am élie Bruandet Guillaume Piessen Clarisse Eveno Source Type: research

Gene Expression Profile-Guided Personalized Intraperitoneal Chemotherapy for Gastric Cancer Peritoneal Carcinomatosis
CONCLUSIONS: Developing algorithms of personalized systemic and intraperitoneal chemotherapy in patients with GC with synchronous carcinomatosis, based on the analysis of molecular genetic characteristics of the tumor and metastases, allows to improve the long-term results of combined treatment.PMID:38545480 | PMC:PMC10965258 | DOI:10.14740/wjon1578 (Source: Cancer Control)
Source: Cancer Control - March 28, 2024 Category: Cancer & Oncology Authors: Vitaly A Markovich Sergey A Tuzikov Evgeny O Rodionov Natalia O Popova Matvey M Tsyganov Sergey V Miller Danil V Podolko Irina A Tsydenova Marina K Ibragimova Nikolai V Litviakov Source Type: research

Ovarian Cancer in the Older Manitoban Population-Treatment Tolerance and Cancer-Related Outcomes: A Manitoba Ovarian Cancer Outcomes (MOCO) Group Study
CONCLUSIONS: Our study demonstrated a high rate of chemotherapy dose reduction and discontinuation in the elderly epithelial ovarian cancer population. Further research is needed to identify risk factors for treatment discontinuation and intolerance in this population.PMID:38534935 | DOI:10.3390/curroncol31030102 (Source: Current Oncology)
Source: Current Oncology - March 27, 2024 Category: Cancer & Oncology Authors: Lesley F Roberts Pascal Lambert Mark W Nachtigal Alon D Altman Erin Dean Source Type: research

Ovarian Cancer in the Older Manitoban Population-Treatment Tolerance and Cancer-Related Outcomes: A Manitoba Ovarian Cancer Outcomes (MOCO) Group Study
CONCLUSIONS: Our study demonstrated a high rate of chemotherapy dose reduction and discontinuation in the elderly epithelial ovarian cancer population. Further research is needed to identify risk factors for treatment discontinuation and intolerance in this population.PMID:38534935 | PMC:PMC10969362 | DOI:10.3390/curroncol31030102 (Source: Current Oncology)
Source: Current Oncology - March 27, 2024 Category: Cancer & Oncology Authors: Lesley F Roberts Pascal Lambert Mark W Nachtigal Alon D Altman Erin Dean Source Type: research