A rare case of peritoneal metastases from oropharyngeal squamous cell carcinoma in a young male after completion of chemoradiotherapy
J Cancer Res Ther. 2023 Jan 1;19(Suppl 2):S954-S957. doi: 10.4103/jcrt.jcrt_163_22. Epub 2023 Apr 29.ABSTRACTDistant metastases are frequent in head and neck squamous cell carcinomas (HNSCC), but they are limited to some organs like lungs, bone, mediastinum, liver and brain. Peritoneal metastases (PMs) from HNSCC are extremely rare. A 28-year-old chronic smoker and alcoholic was diagnosed with squamous cell carcinoma of oropharynx. Patient was admitted and was given six cycles of concurrent chemo and radiotherapy (CCRT) and was discharged. Two months later, he presented with abdominal pain and lump. Contrast-enhanced CT re...
Source: Cell Research - February 22, 2024 Category: Cytology Authors: Abhishek Aggarwal Gunjan Jindal Shubhangi Gupta Manisha Ruchandani Source Type: research

Prevalence and spectrum of germline BRCA1 and BRCA2 in a cohort of ovarian cancer patients from the Salento peninsula (Southern Italy): a matter of preventive health
CONCLUSIONS: This study reveals that the prevalence of germline mutations in the BRCA1 and BRCA2 genes was higher than reported by other studies. A broader understanding of the prevalence and role of BRCA mutations in development, response to treatment, and prognosis represents an exciting and developing area of ovarian cancer treatment and prevention.PMID:38386807 | PMC:PMC10883683 | DOI:10.18632/oncotarget.28561 (Source: Oncotarget)
Source: Oncotarget - February 22, 2024 Category: Cancer & Oncology Authors: Elisabetta De Matteis Maria Rosaria Tumolo Paolo Tarantino Mariangela Ciccarese Tiziana Grassi Francesco Bagordo Maria Rita De Giorgio Emanuele Rizzo Graziana Ronzino Source Type: research