Peripheral Vascular Disease (PVD) Blogs This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Wireless Lumee Oxygen Platform Cleared in EU
The European Union cleared Profusa’s Wireless Lumee Oxygen Platform, a system designed to measure tissue oxygen levels in patients with diseases such as peripheral artery disease and critical limb ischemia. The wired version of the Lumee was cleared in Europe back in 2016 and the new device fundamentally works the same. It consists of a small hydrogel sensor, which comes with its own injector, that has fluorescent particles attached to its body. An electronic wireless patch is placed over the spot where the sensor is injected under the skin. When the fluorescent molecules come in contact with oxygen they can be ma...
Source: Medgadget - February 7, 2020 Category: Medical Devices Authors: Medgadget Editors Tags: Anesthesiology Cardiac Surgery Cardiology Critical Care Emergency Medicine Vascular Surgery Source Type: blogs

SELUTION SLR Drug Eluting Balloon Cleared by EU
MedAlliance, a Swiss company, won the EU CE Mark clearing its SELUTION SLR sirolimus-eluting balloon for use in treating peripheral vascular disease. This is the first CE Mark that the company has received and the clearance applies to SELUTION SLR devices in sizes from 2.0 x 20mm to 7.0 x 150mm. MedAlliance’s technology allows sirolimus, an antiproliferative drug, to be released comparatively to how many existing drug-eluting stents release this medication. Thanks to tiny identical balls within the balloon, made of a biodegradable polymer mixed with the sirolimus, the medicine seeps into the surrounding tissue...
Source: Medgadget - February 5, 2020 Category: Medical Devices Authors: Medgadget Editors Tags: Cardiology Vascular Surgery Source Type: blogs

Detecting Heart Conditions Faster: The Case for Biomarkers-PLUS-AI | Dean Loizou, Prevencio
BY JESSICA DAMASSA Can artificial intelligence help prevent cardiovascular diseases? Biotech startup, Prevencio, has developed a proprietary panel of biomarkers that uses blood proteins and sophisticated AI algorithms to detect cardiovascular conditions like coronary and peripheral artery disease, aerotic stenosis, risk for stroke and more. Dean Loizou, Prevencio’s VP of Business Development, breaks down the process step-by-step and explains exactly how Prevencio reports its clinically viable scores to doctors. How does the AI fit into all this? We get to that too, plus the details around this startup’s plan...
Source: The Health Care Blog - January 24, 2020 Category: Consumer Health News Authors: Grishma Reddy Tags: Health Tech Jessica DaMassa WTF Health Artificial intelligence Bayer G4A Signing Day Biotech Dean Loizou heart disease Prevencio Source Type: blogs

Interview with Medtronic ’s Mark Pacyna on Approval of IN.PACT AV DCB for Failing AV Fistulae
End-stage renal disease (ESRD) patients experiencing kidney failure typically require hemodialysis in order to artificially remove fluid and waste from blood and maintain appropriate electrolyte concentrations. For many patients on hemodialysis, an arteriovenous (AV) fistula is created to link an artery to a vein. Veins are too fragile for frequent access, but arteries are too deep. Creating an AV fistula makes the vein that is linked to an artery more resilient and capable of providing regular vascular access for dialysis. While effective, and a standard of care for ESRD patients, vessel restenosis can occur over time ...
Source: Medgadget - December 5, 2019 Category: Medical Devices Authors: Medgadget Editors Tags: Exclusive Medicine Vascular Surgery Source Type: blogs

Study supports benefit of statin use for older adults
In this study, the most common reason that patients or their doctors stopped statins was the development of advanced cancer or other major illness. In my practice, I have also cared for many patients who have stopped taking statins or who express reluctance to take statins due to side effects. The most common side effect is muscle ache (typically tenderness or soreness of the large muscle groups, such as the biceps and thighs), which affects about 20% of statin takers and reverses when the statin is discontinued. There is also a slightly increased risk of diabetes with long-term statin use and, very rarely, liver problems....
Source: Harvard Health Blog - October 2, 2019 Category: Consumer Health News Authors: Dara K. Lee Lewis, MD Tags: Drugs and Supplements Health Healthy Aging Heart Health Source Type: blogs

Leg pain when you walk? Don ’t ignore it
Walking is often touted as a perfect exercise to improve multiple aspects of health. But what if walking causes leg pain? Many people shrug off leg pain when they walk as a normal part of aging. In some cases, though, it’s the sign of peripheral artery disease (PAD), which can put heart and brain health at risk. While PAD doesn’t usually run in families, it’s more likely to occur as people age, or among people who smoke or have high blood pressure, high cholesterol, or diabetes. What causes leg pain if you have PAD? People with PAD have fatty deposits in arteries outside the heart — most often in their legs. Pain o...
Source: Harvard Health Blog - September 6, 2019 Category: Consumer Health News Authors: Kelly Bilodeau Tags: Exercise and Fitness Healthy Aging Heart Health Hypertension and Stroke Pain Management Source Type: blogs

Suitable Antigens can Attract T Helper Cells that Act to Promote Blood Vessel Regrowth
The immune system is deeply involved in the intricate, complex processes of tissue regeneration, and the research community has much left to catalog of the countless interactions that take place between immune cells and other cell populations during regeneration. One interesting discovery is that a subclass of T helper cells can encourage growth of blood vessels. Thus, given a way of attracting and retaining the appropriate T helper cells in a tissue suffering ischemia, it may be possible to encourage sufficient regrowth of blood vessels to treat conditions involving inadequate blood flow, such as critical limb ischemia. R...
Source: Fight Aging! - August 15, 2019 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Biomaterial Tricks Immune System to Grow New Blood Vessels
Researchers from Harvard’s Wyss Institute have developed a new biomaterial that can activate T cells to promote vascularization of ischemic tissues. Their work demonstrates that the biomaterial results in local blood vessel development, increased perfusion, and new muscle growth after ischemia. Various compounds have been tested to try to improve angiogenesis in tissues that have undergone ischemia, but they have failed in various ways. New interest has developed in using the body’s own immune system to help aid this process. To this end, the Wyss researchers developed unique biomaterials to modulate the local i...
Source: Medgadget - August 7, 2019 Category: Medical Devices Authors: Siavash Parkhideh Tags: Cardiac Surgery Materials Plastic Surgery Rehab Vascular Surgery Source Type: blogs

Fight Aging! Newsletter, June 24th 2019
This study sought to investigate what could be learned from how these men have fared. The men were born in 1925-1928 and similar health-related data from questionnaires, physical examination, and blood samples are available for all surveys. Survival curves over various variable strata were applied to evaluate the impact of individual risk factors and combinations of risk factors on all-cause deaths. At the end of 2018, 118 (16.0%) of the men had reached 90 years of age. Smoking in 1974 was the strongest single risk factor associated with survival, with observed percentages of men reaching 90 years being 26.3, 25.7, ...
Source: Fight Aging! - June 23, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Extracting Evidence for Causation from the Correlation Between Excess Fat Tissue and Risk of Cardiovascular Disease
Given a good enough data set, there are ways to produce evidence for causation in the observed relationships between patient characteristics and risk of age-related disease. While it is well accepted by now that being overweight does in fact cause a raised risk of all the common age-related diseases, a shorter life expectancy, and a raised lifetime medical expenditure, more data never hurts. Researchers have a good understanding of the mechanisms involved in these relationships. In particular, visceral fat tissue around the abdominal organs generates chronic inflammation, which acts to accelerate tissue decline and age-rel...
Source: Fight Aging! - June 18, 2019 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Brain health rests on heart health: Guidelines for lifestyle changes
Right now the world is experiencing an epidemic that is projected to get much, much worse. It’s an epidemic of dementia, affecting 50 million people and millions more of their caregivers — staggering numbers that are projected to triple by 2050. The dementia crisis is such a massive worldwide issue that the World Health Organization (WHO) announced a strategic public health action plan, including compiling an organized database of quality dementia research and creating guidelines for the prevention of dementia. The guidelines have just been published, a 96-page document that is summarized here, as well as in this post....
Source: Harvard Health Blog - June 12, 2019 Category: Consumer Health News Authors: Monique Tello, MD, MPH Tags: Alzheimer's Disease Brain and cognitive health Exercise and Fitness Healthy Aging Memory Nutrition Source Type: blogs

Cardiovascular risk in cancer survivors
Improvements in cancer care has its impact on better survival of those with early stage disease in several malignancies. In this scenario, cardiovascular disease has become a competing cause of death. It is not just due to chemotherapy induced myocardial disease, but also due to common risk factors for cardiovascular disease in this population. Hypertension, cigarette smoking and loss of cardiovascular fitness are some of them [1]. Weight gain may be also a problem in some. Those who have survived cancer for over 5 years have a 1.3 to 3.6 fold increased risk of cardiovascular mortality. Increased incidence of cardiovascu...
Source: Cardiophile MD - May 21, 2019 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Cardiology Source Type: blogs

Diabetes: What price comfort and habit?
I was in suburban Chicago recently one morning, hoping to get something to eat for breakfast. I’d heard that the Panera chain was now serving breakfast that you could order any way you wanted. It’s called “Panera Bread,” but I thought I’d give it a try, as I’ve safely consumed their salads in past. At the counter, I placed my order for 3 eggs over easy, sausage, and bacon—not perfect, given our inability to scrutinize foods and ingredients in such places, but I was willing to try. Obviously, I turned down the breads/toasts that were included. The middle-aged Hispanic woman behind t...
Source: Wheat Belly Blog - May 15, 2019 Category: Cardiology Authors: Dr. Davis Tags: Wheat Belly diabetes grain-free grains Inflammation sugar undoctored Source Type: blogs

Aspirin for primary prevention of cardiovascular disease, part 2
Update In March 2019, the American College of Cardiology (ACC) and the American Heart Association (AHA) released new guidelines that suggest that most adults without a history of heart disease should not take low-dose daily aspirin to prevent a first heart attack or stroke. Based on the ASPREE, ARRIVE, and ASCEND trials, the ACC/AHA guidelines concluded that the risk of side effects from aspirin, particularly bleeding, outweighed the potential benefit. The new guidelines do not pertain to people with established cardiovascular disease, in whom the benefits of daily aspirin have been found to outweigh the risks. ___________...
Source: Harvard Health Blog - March 14, 2019 Category: Consumer Health News Authors: Deepak Bhatt, MD, MPH Tags: Heart Health Prevention Source Type: blogs

The Essential Checklist for Ankle Dislocations
Immediate relocation of ankle dislocations is necessary to preserve the vascular or neurological integrity of the lower extremity and relieve extreme pain. Literature reviews reveal that early reduction followed by a short period of immobilization (six to 12 weeks) and functional or physical rehabilitation produce good clinical outcomes. (Injury 2017;48[10]:2027).Left ankle dislocation from a football accident. Photo by M. Roberts.Ankle dislocations occur from blunt or traumatic incidents such as sporting events (football, gymnastics), motor vehicle crashes, falling, or jumping. Patients may state that their toes we...
Source: The Procedural Pause - March 1, 2019 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs