Leg pain when you walk? Don ’t ignore it
Walking is often touted as a perfect exercise to improve multiple aspects of health. But what if walking causes leg pain? Many people shrug off leg pain when they walk as a normal part of aging. In some cases, though, it’s the sign of peripheral artery disease (PAD), which can put heart and brain health at risk. While PAD doesn’t usually run in families, it’s more likely to occur as people age, or among people who smoke or have high blood pressure, high cholesterol, or diabetes. What causes leg pain if you have PAD? People with PAD have fatty deposits in arteries outside the heart — most often in their legs. Pain occurs because these deposits block blood flow to the muscles, impairing their ability to work properly. Doctors used to think PAD mostly affected men. But when researchers began to include more women in their studies, they learned that the condition is just as common in women, affecting one in every 10 women over age 50 and one in every five over 60, says Dr. Aruna Pradhan, a cardiologist and assistant professor of medicine at Harvard Medical School. Pay attention to the pattern of leg pain The cramping and pain in the calves, thighs, hips, or buttocks that people with PAD experience during movement is called intermittent claudication. It’s different from exercise-related soreness, because it occurs only during movement and stops after short periods of rest, says Dr. Pradhan. Muscle soreness caused by exercise lasts for hours or days af...
Publication date: Available online 26 February 2020Source: Clinical Lymphoma Myeloma and LeukemiaAuthor(s): Ben Ponvilawan, Nipith Charoenngam, Thanitsara Rittiphairoj, Patompong Ungprasert
Authors: Gavrila IL, Badea RI, Jude C, Socaciu MA, Comsa M, Badea AF Abstract Abdominal ultrasound (US) performed as a "primary imaging procedure" is an important diagnostic tool in gastroenterol-ogy. Expanding the routine investigation to the lower thoracic region might sometimes accelerate the diagnosis in inconclusive manifestations such as pulmonary pathology.US is a valuable tool in evaluating patients with breathing difficulties, chest pain, hypoxia, or chest trauma. This paper presents the particular situation of a patient hospitalized in the gastroenterology depart-ment, where the US identified si...
Authors: Roman A, Palego F, Achimas-Cadariu P, Vlad C, Andries A, Tomuleasa CI, Gata VA, Pintican R, Rada MP, Feier D Abstract AimsThe present study aims to investigate the pain, anxiety and other factors that are associated with percutaneous computed tomography (CT)- and ultrasound (US)-guided biopsies of tumors.Material and MethodsThe study prospectively included 60 consecutive patients, of which 24 underwent CT-guided biopsies and 36 US-guided biopsies. The location of targeted tumors was within the thorax, abdomen, pelvis, and limbs. A questionnaire containing numerical rate scales (0-10) regarding procedural a...
Publication date: Available online 25 February 2020Source: Progress in Neuro-Psychopharmacology and Biological PsychiatryAuthor(s): Su-Ying Cui, Yuan-Li Huang, Xiang-Yu Cui, Hui-Ling Zhao, Xiao Hu, Yu-Tong Liu, Yu Qin, Nurhumar Kurban, Yong-He Zhang
Abstract Organisms encounter a wide range of toxic compounds in their environments, from chemicals that serve anticonsumption or anticompetition functions to pollutants and pesticides. Although we understand many detoxification mechanisms that allow organisms to consume toxins typical of their diet, we know little about why organisms vary in their ability to tolerate entirely novel toxins. We tested whether variation in generalized stress responses, such as antioxidant pathways, may underlie variation in reactions to novel toxins and, if so, their associated costs. We used an artificial diet to present cabbage whi...
Publication date: 25 February 2020Source: Cell Reports, Volume 30, Issue 8Author(s): Maurizio Di Marzo, Humberto Herrera-Ubaldo, Elisabetta Caporali, Ondřej Novák, Miroslav Strnad, Vicente Balanzà, Ignacio Ezquer, Marta A. Mendes, Stefan de Folter, Lucia Colombo
CONCLUSION: All these results indicate that SQC is an effective preventive and protective drug on skeletal muscle of diabetic macrovasculopathy, and could alleviate skeletal muscle tissue damage through affecting biological functions related to cell death and cell adhesion. PMID: 32096754 [PubMed - as supplied by publisher]
Publication date: Available online 25 February 2020Source: Neuroscience LettersAuthor(s): Jie Li, Binke Yuan, Guoxiong Li, Xingqi Lu, Yun Guo, Ying Yang, Minjie Liang, Jianping Ding, Quan Zhou
We report the case of a 6-year-old child with anomalous origin of right coronary artery from aortic left coronary sinus, who underwent elective surgical replacement of stenotic and calcified conduit between the right ventricle and the main pulmonary artery. The surgery was complicated by acute myocardial infarction secondary to coronary extrinsic compression. The patient was successfully treated with urgent percutaneous coronary intervention (simultaneous V-stenting) and cangrelor infusion, subsequently switched to clopidogrel therapy. PMID: 32090666 [PubMed - as supplied by publisher]
This study (NCT03381742) retrospectively analyzed the data from 11 hospitals on 3,043 patients with coronary artery disease, who received C75QD, T90BID, ticagrelor 45 mg BID (T45BID), or ticagrelor 90 mg QD (T90QD). Compared with C75QD, both T45BID and T90QD showed significantly higher inhibition of platelet aggregation (P
More News: Angiography | Aspirin | Blogging | Brain | Cardiology | Cardiovascular | Cholesterol | Diabetes | Diets | Endocrinology | Fruit | Harvard | Health | Heart | Heart Attack | Hypertension | Intermittent Claudication | Neurology | Nutrition | Pain | Pain Management | Peripheral Vascular Disease (PVD) | Smokers | Sports Medicine | Statin Therapy | Stroke | Study | Vegetables | Women | X-Ray