SAGES peritoneal dialysis access guideline update 2023
ConclusionsIn the adult population, conditional recommendations were made in favor of: staged hernia repair followed by PD catheter insertion over simultaneous and traditional start over urgent start of PD when medically possible. Furthermore, the panel suggested advanced laparoscopic insertion techniques rather than basic laparoscopic techniques or open insertion. Conditional recommendations were made for either advanced laparoscopic or image-guided percutaneous insertion and for either nonoperative or operative salvage. A recommendation could not be made regarding concomitant clean-contaminated surgery in adults. In the ...
Source: Surgical Endoscopy - November 21, 2023 Category: Surgery Source Type: research
Neonatal surfactant therapy beyond respiratory distress syndrome
Whilst exogenous surfactant therapy is central to the management of newborn infants with respiratory distress syndrome, its use in other neonatal lung diseases remains inconsistent and controversial. Here we discuss the evidence and experience in relation to surfactant therapy in newborns with other lung conditions in which surfactant may be deficient or dysfunctional, including meconium aspiration syndrome, pneumonia, congenital diaphragmatic hernia and pulmonary haemorrhage. We find that, for all of these diseases, administration of exogenous surfactant as bolus therapy is frequently associated with transient improvement...
Source: Seminars in Fetal and Neonatal Medicine - November 21, 2023 Category: Perinatology & Neonatology Authors: Peter A. Dargaville, Egbert Herting, Roger F. Soll Source Type: research
Characterization of the congenital diaphragmatic hernia model in C57BL/6J fetal mice: a step toward lineage tracing experiments
ConclusionModeling CDH in C57BL/6J mouse fetuses is effective in reproducing the classical CDH hallmarks. This model will be critical for lineage tracing experiments. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - November 20, 2023 Category: Surgery Source Type: research
Long-term pulmonary outcome of children with congenital diaphragmatic hernia: functional lung MRI using matrix-pencil decomposition enables side-specific assessment of lung function
ConclusionsData indicate impaired overall lung function with particular limitation of the ipsilateral side in patients with a large CDH. MP-MRI is a promising tool to provide valuable side-specific functional information in the follow-up of patients with CDH.Clinical relevance statementIn patients with congenital diaphragmatic hernia, easily applicable MP-MRI allows specific examination of the lung side affected by the hernia and provides valuable information on ventilation and perfusion with implications for clinical practice, making it a promising tool for routine follow-up.Key Points• Functional matrix pencil decompos...
Source: European Radiology - November 20, 2023 Category: Radiology Source Type: research
Characterization of the congenital diaphragmatic hernia model in C57BL/6J fetal mice: a step toward lineage tracing experiments
ConclusionModeling CDH in C57BL/6J mouse fetuses is effective in reproducing the classical CDH hallmarks. This model will be critical for lineage tracing experiments. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - November 20, 2023 Category: Surgery Source Type: research
The role of point-of-care ultrasound in the management of neonates with congenital diaphragmatic hernia
Pediatr Res. 2023 Nov 17. doi: 10.1038/s41390-023-02889-4. Online ahead of print.ABSTRACTIn the last few years, current evidence has supported the use of point-of-care ultrasound (POCUS) for a number of diagnostic and procedural applications. Considering the valuable information that POCUS can give, we propose a standardized protocol for the management of neonates with a congenital diaphragmatic hernia (CDH-POCUS protocol) in the neonatal intensive care unit. Indeed, POCUS could be a valid tool for the neonatologist through the evaluation of 1) cardiac function and pulmonary hypertension; 2) lung volumes, postoperative ple...
Source: Pediatric Research - November 18, 2023 Category: Pediatrics Authors: Chiara Maddaloni Domenico Umberto De Rose Sara Ronci Flaminia Pugnaloni Ludovica Martini Stefano Caoci Iliana Bersani Andrea Conforti Francesca Campi Roberta Lombardi Irma Capolupo Paolo Tom à Andrea Dotta Flaminia Calzolari Source Type: research
The role of point-of-care ultrasound in the management of neonates with congenital diaphragmatic hernia
Pediatr Res. 2023 Nov 17. doi: 10.1038/s41390-023-02889-4. Online ahead of print.ABSTRACTIn the last few years, current evidence has supported the use of point-of-care ultrasound (POCUS) for a number of diagnostic and procedural applications. Considering the valuable information that POCUS can give, we propose a standardized protocol for the management of neonates with a congenital diaphragmatic hernia (CDH-POCUS protocol) in the neonatal intensive care unit. Indeed, POCUS could be a valid tool for the neonatologist through the evaluation of 1) cardiac function and pulmonary hypertension; 2) lung volumes, postoperative ple...
Source: Pediatric Research - November 18, 2023 Category: Pediatrics Authors: Chiara Maddaloni Domenico Umberto De Rose Sara Ronci Flaminia Pugnaloni Ludovica Martini Stefano Caoci Iliana Bersani Andrea Conforti Francesca Campi Roberta Lombardi Irma Capolupo Paolo Tom à Andrea Dotta Flaminia Calzolari Source Type: research
Novel mutation in ELN gene causes cardiac abnormalities and inguinal hernia: case report
Elastin-driven genetic diseases are a group of complex diseases driven by elastin protein insufficiency and dominant-negative production of aberrant protein, including supravalvular aortic stenosis (SVAS) and ... (Source: BMC Pediatrics)
Source: BMC Pediatrics - November 18, 2023 Category: Pediatrics Authors: Hua-yong Zhang, Min Xiao and Yong Zhang Tags: Case report Source Type: research
The evidence mismatch in pediatric surgical practice
ConclusionsPublished literature concerning common outpatient pediatric surgical conditions is sparse and demonstrates wide variations in practice. All individual practice choices were justified using either risk of complications or patient preference. Most early intervention practices were based on weak or outdated studies and “common wisdom” rather than genuine evidence.Level of evidenceIII. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - November 18, 2023 Category: Surgery Source Type: research
Efficacy and safety of laparoscopic assisted transversus abdominis plane block in the analgesia after pediatric inguinal hernia surgery
Asian J Surg. 2023 Nov 15:S1015-9584(23)01702-5. doi: 10.1016/j.asjsur.2023.10.089. Online ahead of print.NO ABSTRACTPMID:37977926 | DOI:10.1016/j.asjsur.2023.10.089 (Source: Asian Journal of Surgery)
Source: Asian Journal of Surgery - November 17, 2023 Category: Surgery Authors: Huiying Zhang Zehong Huang Chunming Guo Zhongliang Lin Source Type: research
Efficacy and safety of laparoscopic assisted transversus abdominis plane block in the analgesia after pediatric inguinal hernia surgery
Asian J Surg. 2023 Nov 15:S1015-9584(23)01702-5. doi: 10.1016/j.asjsur.2023.10.089. Online ahead of print.NO ABSTRACTPMID:37977926 | DOI:10.1016/j.asjsur.2023.10.089 (Source: Asian Journal of Surgery)
Source: Asian Journal of Surgery - November 17, 2023 Category: Surgery Authors: Huiying Zhang Zehong Huang Chunming Guo Zhongliang Lin Source Type: research
Congenital diaphragmatic hernia: quality improvement using a maximal lung protection strategy and early surgery-improved survival
Conclusion: MLP with early surgery significantly improved survival and additional adverse outcomes of neonates with CDH. Prospective randomized studies are necessary to confirm the findings of the current study.What is Known:• Ventilator-induced lung injury was reported as the main cause of mortality in neonates with congenital diaphragmatic hernia (CDH).• Conventional ventilation is recommended by the European CDH consortium as the first-line ventilation modality; timing of surgery is controversial.What is New:• A maximal lung protection strategy based on 15-Hz high-frequency oscillatory ventilation with low dist...
Source: European Journal of Pediatrics - November 17, 2023 Category: Pediatrics Source Type: research
Letter to the Editor: Laparoscopic Pediatric Inguinal Hernia Repair Does Not Necessarily Require Prophylactic Antibiotic Agents
Surgical Infections,Volume 24, Issue 9, Page 843-844, November 2023. (Source: Surgical Infections)
Source: Surgical Infections - November 17, 2023 Category: Surgery Authors: Yuki Muta Akio Odaka Seiichiro Inoue Yuta Takeuchi Yoshifumi Beck Source Type: research
Anti-inflammatory effects of antenatal administration of stem cell derived extracellular vesicles in the brain of rat fetuses with congenital diaphragmatic hernia
ConclusionThis study shows that the brain of rat fetuses with CDH has signs of inflammation that are abated by the intra-amniotic administration of AFSC-EVs. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - November 13, 2023 Category: Surgery Source Type: research
