Provincial review of adherence to age-specific guidelines for umbilical hernia repair and trends in management
Umbilical hernia (UH) is a common pediatric condition, for which delaying surgical repair for asymptomatic UH until after age 3 is recommended due to a high incidence of spontaneous closure. We aimed to determine the adherence to guidelines, rate of urgent surgical repair, outcomes, cost, and interinstitutional referral patterns of UH repair in the province of Quebec (Canada). (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - February 3, 2024 Category: Surgery Authors: Shadi Hadj-Youssef, F élix Rondeau, Kossi Thomas Golo, Nizar Ghali, Maude Laberge, Patricia Li, Marc Beltempo, Guy Lacroix, Hussein Wissanji Source Type: research

Causes of recurrence of paediatric inguinal hernia after single-port laparoscopic closure
ConclusionThe main cause of recurrence is improper ligation. Tension-free and complete PIH ligation are critical to the success of surgery, which requires avoiding the peritoneum skip area and the subcutaneous and muscular tissues. Redo-laparoscopic surgery was suitable for the treatment of recurrent inguinal hernia (RIH). For giant hernias, direct ligation of the internal ring incorporating the medial umbilical ligament (DIRIM) may be needed. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - February 2, 2024 Category: Surgery Source Type: research

Accuracy of estimated fetal weight assessment in fetuses with congenital diaphragmatic hernia – Is the Hadlock formula a reliable tool?
Introduction and aims of the study: Congenital diaphragmatic hernia (CDH) is defined as organ protrusion from the abdominal to thethoracic cavity. The Hadlock formula is the most commonly used tool for calculating estimated fetalweight (EFW).The anatomical nature of CDH usually leads to underestimation of the abdominal circumference, resulting in underestimation of fetal weight. We investigated whether the EFW error margin differs between infants with isolated CDH and matched controls. Apart from Hadlock, we used a new formula, designed especially for fetuses with CDH, to determine the superiority of either method (Source:...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 1, 2024 Category: OBGYN Authors: Daria Kuchnowska, Przemys ław Kosinski, Albert Stachura, Maciej Gawlak, Piotr Wegrzyn Source Type: research

Predictors of mortality in very low birth weight neonates with congenital diaphragmatic hernia
This study aims to quantify and determine predictors of mortality in VLBW neonates with CDH. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - January 30, 2024 Category: Surgery Authors: Emily Nes, Priyanka V. Chugh, Gregory Keefe, Katherine Culbreath, Kate A. Morrow, Danielle E.Y. Ehret, Roger F. Soll, Jeffrey D. Horbar, Matthew T. Harting, Kevin P. Lally, Biren P. Modi, Tom Jaksic, Erika M. Edwards Source Type: research

Dysregulation of CITED2 in abnormal lung development in the nitrofen rat model
ConclusionOur data suggest that dysregulation of CITED2 contributes to abnormal lung development of CDH, as demonstrated by the distinct spatial –temporal distribution in nitrofen-induced lungs. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - January 30, 2024 Category: Surgery Source Type: research

Surfactant Therapy in Congenital Diaphragmatic Hernia and Fetoscopic Endoluminal Tracheal Occlusion
Congenital diaphragmatic hernia (CDH) is a complex pathology with severe pulmonary morbidity. Administration of surfactant in CDH is controversial, and the advent of fetoscopic endoluminal tracheal occlusion (FETO) has added further complexity. While FETO has been shown to improve survival outcomes, there are risks of prematurity and potential surfactant deficiency. We aim to evaluate the characteristics and outcomes of surfactant administration for CDH infants and elucidate potential benefits or risks in this unique population. (Source: Journal of Surgical Research)
Source: Journal of Surgical Research - January 30, 2024 Category: Surgery Authors: Y. Deniz Sevilmis, Oluyinka O. Olutoye, Sarah Peiffer, Steven C. Mehl, Michael A. Belfort, Christopher J. Rhee, Joseph A. Garcia-Prats, Adam M. Vogel, Timothy C. Lee, Sundeep G. Keswani, Alice King Tags: Pediatric Surgery Source Type: research

Increased Elastase and Matrix Metalloproteinase Levels in the Pulmonary Arteries of Infants with Congenital Diaphragmatic Hernia
Pulmonary vascular disease (PVD) complicated with pulmonary hypertension (PH) is a leading cause of mortality in congenital diaphragmatic hernia (CDH). Unfortunately, CDH patients are often resistant to PH therapy. Using the nitrofen CDH rat model, we previously demonstrated that CDH-associated PVD involves an induction of elastase and matrix metalloproteinase (MMP) activities, increased osteopontin and epidermal growth factor (EGF) levels, and enhanced smooth muscle cell (SMC) proliferation. Here, we aimed to determine whether the levels of the key members of this proteinase-induced pathway are also elevated in the pulmon...
Source: Journal of Pediatric Surgery - January 29, 2024 Category: Surgery Authors: Jui-Hsia Hung, St éphanie Langlois, Meagan Wiebe, Benjamin Wild, Jessica Barré-Dunn, Kyle N. Cowan Source Type: research

Can inguinal hernia be a negative consequence of human evolution?
Surgical repair of inguinal hernia remain the most frequently performed procedure in children1. Despite the well-established facts regarding this congenital anomaly, certain aspects remain unresolved, familiar to pediatric surgeons. The statement, endorsed by numerous authors, "The final chapter of inguinal hernia is yet to be written," underscores the existence of unilluminated aspects alongside widely known facts. The incidence of inguinal hernia in term newborns varies from 1-5%, escalating to 30% in premature infants2. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - January 29, 2024 Category: Surgery Authors: Sinan K ılıç Source Type: research

Risk Factors for Preoperative Pneumothorax in Neonates With Isolated Left-Sided Congenital Diaphragmatic Hernia: An International Cohort Study
We aimed to investigate the clinical characteristics and outcomes of patients with isolated left-sided congenital diaphragmatic hernia (CDH) who developed preoperative pneumothorax and determine its risk factors. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - January 29, 2024 Category: Surgery Authors: Kazunori Masahata, Kouji Nagata, Keita Terui, Takuya Kondo, Ashley H. Ebanks, Matthew T. Harting, Terry L. Buchmiller, Yasunori Sato, Hiroomi Okuyama, Noriaki Usui, Congenital Diaphragmatic Hernia Study Group Source Type: research

Assessment of mediastinal shift angles in congenital pulmonary airway malformation: a new fetal magnetic resonance imaging indicator of congenital lung disease
ConclusionThe mediastinal shift angle has potential to replace the CPAM volume ratio for evaluating the severity of CPAM in  fetal MRI.Graphical Abstract (Source: Pediatric Radiology)
Source: Pediatric Radiology - January 29, 2024 Category: Radiology Source Type: research

Femoral hernia in pediatric population: a diagnostic and surgical challenge
ConclusionDue to the high rate of misdiagnosis, the variety of surgical approaches proposed, and the potential for intraoperative complications, FH poses a challenge for pediatric surgeons and urologists, as confirmed by the literature. It is essential to underline the importance of a proper clinical examination in order to correctly diagnose FH, make the best surgical plan for the patient and prevent post-operative complications. (Source: Hernia)
Source: Hernia - January 25, 2024 Category: Sports Medicine Source Type: research

A Narrative Review of Patient-Reported Outcome Measures and Their Application in Recent Pediatric Surgical Research: Advancing Knowledge and Offering New Perspectives to the Field
Conclusions This review reveals gaps in the application of PROMs in recent pediatric surgical research. Emphasis should be placed on the development and utilization of psychometrically robust PROMs, broadening the scope of covered diseases, conducting impact assessments, and evaluating implementation strategies. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - January 25, 2024 Category: Surgery Authors: Spivack, Olivia K.C. Dellenmark-Blom, Michaela Dingemann, Jens ten Kate, Chantal A. Wallace, Vuokko Bramer, Wichor M. Quitmann, Julia H. Rietman, Andre Tags: Review Article Source Type: research

Femoral hernia in pediatric population: a diagnostic and surgical challenge
ConclusionDue to the high rate of misdiagnosis, the variety of surgical approaches proposed, and the potential for intraoperative complications, FH poses a challenge for pediatric surgeons and urologists, as confirmed by the literature. It is essential to underline the importance of a proper clinical examination in order to correctly diagnose FH, make the best surgical plan for the patient and prevent post-operative complications. (Source: Hernia)
Source: Hernia - January 25, 2024 Category: Sports Medicine Source Type: research