Literature review on the bilateral occurrence of invasive lobular breast cancer
Invasive lobular carcinoma (ILC) is a type of breast cancer characterized by the loss of E-cadherin expression, leading to discohesion between tumour cells [1]. This phenomenon explains the multifocal growth pattern and diffuse infiltration observed in ILC [2,3]. ILC is the second most common histological type of invasive breast cancer, following invasive breast cancer of no special type (NST) [4]. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 30, 2024 Category: OBGYN Authors: Griet Verboven, Imke Lodewijkx, Laura Van den Bosch, Manon Huizing, Mireille Van Goethem, Glenn Broeckx, Wiebren A. Tjalma Tags: Full length article Source Type: research
Retrospective cohort study on the bilateral occurrence of invasive lobular breast cancer
Breast cancer is a prevalent and significant health concern globally. It is crucial to conduct research to enhance our understanding of this disease, particularly in Belgium. Belgium holds the highest age-standardized incidence rate for breast cancer worldwide [1]. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 30, 2024 Category: OBGYN Authors: Griet Verboven, Laura Van den Bosch, Imke Lodewijkx, Manon Huizing, Mireille Van Goethem, Glenn Broeckx, Wiebren A. Tjalma Source Type: research
Validity of a Delphi consensus definition of growth restriction in the newborn for identifying neonatal morbidity
Small-for-gestational age (SGA) is defined as a birthweight below a birthweight-percentile threshold, usually the 10th percentile, with the 3rd or 5th percentile used to identify severe SGA. SGA is used as a proxy for growth restriction in the newborn, but SGA newborns can be physiologically small and healthy. This definition also excludes growth restricted newborns who have weights above the 10th percentile. To address these limits, a Delphi study developed a new consensus definition of growth restriction in the newborn based on neonatal anthropometric and clinical parameters, but it has not been evaluated. (Source: Ameri...
Source: American Journal of Obstetrics and Gynecology - April 30, 2024 Category: OBGYN Authors: Isabelle MONIER, Anne EGO, Alice HOCQUETTE, Alexandra BENACHI, Fran çois GOFFINET, Nathalie LELONG, Camille LE RAY, Jennifer ZEITLIN, ENP2021 Study Group Tags: Original Research: Obstetrics Source Type: research
How severity and classification of pulmonary hypertension affect pregnancy outcomes: a systematic review and timeline
Current consensus guidelines recommend that pregnancy is contraindicated in patients with pulmonary hypertension (PH) due to high maternal and fetal morbidity and mortality.1 In this systematic review we evaluated the data behind these recommendations to determine if all forms and severity of PH should be considered an absolute contraindication to pregnancy. Pulmonary hypertension is a complex disease involving multiple etiologies2 which increase pulmonary blood pressure. It is classified by the WHO (World Health Organization) according to the underlying pathology into five groups: 1. (Source: International Journal of Obstetric Anesthesia)
Source: International Journal of Obstetric Anesthesia - April 30, 2024 Category: Anesthesiology Authors: N.C. Cruz, E. Pham, H. Ali, J Nanavati, D Steppan, TM Kolb, AJ Thomas, J Murphy, S Nyhan, MC Grant, J Steppan Tags: Review Article Source Type: research
Intermediate-risk endometrial cancer treated with adjuvant brachytherapy using single dosimetric planning: long-term outcome and toxicity assessment
The incidence of endometrial carcinoma has increased steadily over the past three decades, emerging as the second most commonly diagnosed gynaecological cancer worldwide, and the most common gynaecological malignancy in high-income countries [1]. It is most commonly diagnosed in early stages, where the 5-year specific survival rate reaches 95%. Nevertheless, the number of deaths related to endometrial cancer continues to rise, despite an increase in global cancer survival rates [2]. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 30, 2024 Category: OBGYN Authors: Abel Cordoba, El Hajj Houssein, Alexandre Escande, Cyrielle Scouarnec, Fabrice Narducci, Carlos Martinez Gomez, Eric Leblanc, Delphine Hudry, Camille Pasquesoone, Sophie Taieb, Xavier Mirabel, Eric F. Lartigau, Florence Le Tinier Tags: Full length article Source Type: research
High Rates of Placental Inflammation Among Samples Collected by the MOMI Consortium
The Multi-Omics for Mothers and Infants (MOMI) consortium aims to improve birth outcomes. Preterm birth is a major obstetric complication globally causing significant infant and childhood morbidity and mortality. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - April 30, 2024 Category: OBGYN Authors: Joshua F. ROBINSON, Sayan DAS, Waqasuddin KHAN, Rasheda KHANAM, Joan T. PRICE, Anisur RAHMAN, Salahuddin AHMED, Said Mohammed ALI, Saikat DEB, Brian DEVEALE, Arup DUTTA, Matthew GORMLEY, Steven C. HALL, A.S.M. Tarik HASAN, Aneeta HOTWANI, Mohamed Hamid JU Tags: Original Research: Obstetrics Source Type: research
EUROPEAN ASSOCIATION OF PERINATAL MEDICINE (EAPM) Position statement: Screening, diagnosis and management of congenital anomalies of the umbilical cord
Congenital anomalies of the umbilical cord are associated with an increased risk of pregnancy and perinatal complications. Some anomalies of the cord have a higher prevalence than other fetal structural anomalies. The most common anomalies are the absence of an umbilical artery and velamentous insertion of the cord (with or without vasa previa). These anomalies, even when not associated with fetal structural defects, increase the risk of adverse perinatal outcome including, fetal growth restriction and stillbirth. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 30, 2024 Category: OBGYN Authors: Eric Jauniaux, Cathrine Ebbing, Yinka Oyelese, Rony Maymon, Federico Prefumo, Amar Bhide Tags: Expert Opinion Source Type: research
Reducing Severe Maternal Morbidity for Birthing Persons with Severe Hypertension through a Statewide Quality Improvement Initiative
Hypertensive disorders of pregnancy are a leading preventable cause of severe maternal morbidity and maternal mortality worldwide. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - April 30, 2024 Category: OBGYN Authors: Ann BORDERS, Lauren KEENAN-DEVLIN, Elissa H. OH, Danielle YOUNG, William GROBMAN, Patricia LEE KING Tags: Original Research: Obstetrics Source Type: research
Covid-19 vaccination during pregnancy is not associated with an increased risk of severe post-partum hemorrhage
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - April 30, 2024 Category: OBGYN Authors: Maria C. Magnus, Trine Damsted Rasmussen, Anne K. Örtqvist, Laura L. Oakley, Stine Kjaer Urhoj, Olof Stephansson, Siri E. Håberg Tags: Research Letter Source Type: research
Expectant management of preeclampsia with severe features diagnosed at less than 24 weeks
The recent ACOG practice bulletin offers no guidance on management of preeclampsia with severe features (PreE with SF) less than 24 weeks. Historically, immediate delivery was recommended due to poor perinatal outcomes and high maternal morbidity. Recently, advances in neonatal resuscitation have led to increased survival at peri-viable gestational ages. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - April 30, 2024 Category: OBGYN Authors: Kristen A. CAGINO, Rylee D. TROTTER, Katherine E. LAMBERT, Saloni C. KUMAR, Baha M. SIBAI Tags: Original Research: Obstetrics Source Type: research
Blood pressure cut-offs at 11-13 weeks ’ gestation and risk of preeclampsia
A parallel has been drawn between first trimester placental vascular maturation and maternal cardiovascular adaptations, including blood pressure. Although 140/90 mmHg is well-accepted as the threshold for chronic hypertension in the general obstetric population in early pregnancy, a different threshold could apply to stratify risk of adverse outcomes, such as preeclampsia. This could have implications for interventions, such as the threshold for initiation of antihypertensive therapy and the target blood pressure level. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - April 30, 2024 Category: OBGYN Authors: Laura J. SLADE, Argyro SYNGELAKI, Milly WILSON, Hiten D. MISTRY, Ranjit AKOLEKAR, Peter VON DADELSZEN, Kypros H. NICOLAIDES, Laura A. MAGEE Tags: Original Research: Obstetrics Source Type: research
Agreement between three noninvasive temperature monitoring devices during spinal anaesthesia for caesarean delivery: a prospective observational study
This study aimed to compare a noninvasive core temperature monitor with two readily available peripheral temperature monitors during obstetric spinal anaesthesia. We undertook a prospective observational study including elective and emergency caesarean deliveries, to determine the agreement between affordable reusable surface temperature monitors (Welch Allyn SureTemp ® Plus oral thermometer and the Braun 3-in-1 No Touch infrared thermometer) and the Dräger T-core© (using dual-sensor heat flux technology), in detecting thermoregulatory changes during obstetric spinal anaesthesia. Predetermined clinically relevant limits...
Source: Journal of Clinical Monitoring and Computing - April 30, 2024 Category: Information Technology Source Type: research
Navigating an unexpected diagnosis - experience of a tertiary referral centre with two cases of intraplacental choriocarcinoma
Malays J Pathol. 2024 Apr;46(1):91-94.ABSTRACTIntraplacental choriocarcinoma is a rare tumour, with approximately 62 reported cases. It may manifest as a spectrum of disease ranging from an incidental lesion diagnosed on routine placental examination to disseminated maternal and/or neonatal disease. In this case series, we presented two rare cases of intraplacental choriocarcinoma with extremely varied clinical presentations. The extremely varied clinical presentations of both patients described in the case series complicated the process of arriving at the diagnosis. In both cases, subsequent investigations showed no mater...
Source: Malaysian Journal of Pathology - April 29, 2024 Category: Pathology Authors: C C W Lim L S Punjabi A Bhatia Q J Ng G P Jevon I M Aggarwal Source Type: research
Seroprevalence of < em > Toxocara < /em > spp. in Pregnant Women: A Systematic Review and Meta-Analysis
CONCLUSIONS: In the present study, significant prevalence was reported; however, considering the limited number of studies, it seems that the actual prevalence of the disease is higher. Therefore, it seems necessary to monitor this health problem in pregnant women.PMID:38682081 | PMC:PMC11055642 | DOI:10.1155/2024/1943353 (Source: Infectious Diseases in Obstetrics and Gynecology)
Source: Infectious Diseases in Obstetrics and Gynecology - April 29, 2024 Category: OBGYN Authors: Sara Shayanfar Saeed Bahadory Ali Taghipour Masoud Foroutan Amir Abdoli Source Type: research
Navigating an unexpected diagnosis - experience of a tertiary referral centre with two cases of intraplacental choriocarcinoma
Malays J Pathol. 2024 Apr;46(1):91-94.ABSTRACTIntraplacental choriocarcinoma is a rare tumour, with approximately 62 reported cases. It may manifest as a spectrum of disease ranging from an incidental lesion diagnosed on routine placental examination to disseminated maternal and/or neonatal disease. In this case series, we presented two rare cases of intraplacental choriocarcinoma with extremely varied clinical presentations. The extremely varied clinical presentations of both patients described in the case series complicated the process of arriving at the diagnosis. In both cases, subsequent investigations showed no mater...
Source: Malaysian Journal of Pathology - April 29, 2024 Category: Pathology Authors: C C W Lim L S Punjabi A Bhatia Q J Ng G P Jevon I M Aggarwal Source Type: research
