Preventing postnatal depression in new mothers using telephone peer support: protocol for the DAISY (Depression and AnxIety peer Support studY) multi-centre randomised controlled trial
Introduction Postnatal depression affects up to one in six new mothers in Australia each year, with significant impacts on the woman and her family. Prevention strategies can be complicated by a woman’s reluctance to seek professional help. Peer support is a promising but inadequately tested early intervention. Very few trials have reported on the efficacy of peer support in the perinatal period and no study has been undertaken in Australia. We will explore if proactive telephone-based peer (mother-to-mother) support, provided to women identified as being at high risk of postnatal depression, impacts on clinically si...
Source: BMJ Open - May 15, 2024 Category: General Medicine Authors: Shafiei, T., McLachlan, H. L., Dennis, C.-L., Nicholson, J. M., Nguyen, T., Shiell, A., Nguyen, C. D., Grimes, H., Bee, J., Adams, C., Callander, E., Forster, D. A. Tags: Open access, Public health Source Type: research

Treat and release: an observational study of non-conveyed high-acuity dispatches in a Danish emergency medical system
The objective of the study was to assess admission to hospital and mortality in non-conveyed patients. This population-based cohort study included all high-acuity dispatches in Region Zealand, Denmark between 2019 and 2022. The primary outcome was admission within 48  h, and the secondary outcome was 30-day mortality. Descriptive statistical analyses were conducted, and logistic regression models were used to estimate adjusted odds ratios and 95% confidence intervals. A non-conveyance rate of 14% was identified in 95,238 transports. Admission within 48 h was s een in 22% of non-conveyed patients vs. 95% in conveyed patie...
Source: Internal and Emergency Medicine - May 15, 2024 Category: Emergency Medicine Source Type: research

Follow-up after major traumatic injury: a survey of services in Australian and New Zealand public hospitals
Increased survival from traumatic injury has led to a higher demand for follow-up care when patients are discharged from hospital. It is currently unclear how follow-up care following major trauma is provided ... (Source: BMC Health Services Research)
Source: BMC Health Services Research - May 15, 2024 Category: General Medicine Authors: Elizabeth Wake, Jamie Ranse, Don Campbell, Belinda Gabbe and Andrea P. Marshall Tags: Research Source Type: research

Cardiovascular outcomes for people hospitalised with COVID-19 in Australia, and the effect of vaccination: an  observational cohort study
CONCLUSIONS: Although troponin levels were elevated in a considerable proportion of people hospitalised with COVID-19, clinical cardiovascular events were infrequent, and their likelihood was not influenced by vaccination. COVID-19 vaccination, however, was associated with reduced likelihood of in-hospital death and intubation.TRIAL REGISTRATION: Australian and New Zealand Clinical Trials Registry, ACTRN12620000486921 (prospective).PMID:38741458 | DOI:10.5694/mja2.52307 (Source: Medical Journal of Australia)
Source: Medical Journal of Australia - May 14, 2024 Category: General Medicine Authors: Hari P Sritharan Kunwardeep S Bhatia William van Gaal Leonard Kritharides Clara K Chow Ravinay Bhindi Source Type: research

Cardiovascular outcomes for people hospitalised with COVID-19 in Australia, and the effect of vaccination: an  observational cohort study
CONCLUSIONS: Although troponin levels were elevated in a considerable proportion of people hospitalised with COVID-19, clinical cardiovascular events were infrequent, and their likelihood was not influenced by vaccination. COVID-19 vaccination, however, was associated with reduced likelihood of in-hospital death and intubation.TRIAL REGISTRATION: Australian and New Zealand Clinical Trials Registry, ACTRN12620000486921 (prospective).PMID:38741458 | DOI:10.5694/mja2.52307 (Source: Med J Aust)
Source: Med J Aust - May 14, 2024 Category: General Medicine Authors: Hari P Sritharan Kunwardeep S Bhatia William van Gaal Leonard Kritharides Clara K Chow Ravinay Bhindi Source Type: research

Plasma and interstitial fluid antibiotic levels of subcutaneously implanted compounded florfenicol calcium sulfate beads in New Zealand White rabbits (Oryctolagus cuniculus)
Am J Vet Res. 2024 May 18:1-10. doi: 10.2460/ajvr.24.02.0044. Online ahead of print.ABSTRACTOBJECTIVE: To determine antibiotic levels in plasma and interstitial fluid (ISF) after SC placement of compounded florfenicol (FF) calcium sulfate beads (CSBs) in New Zealand White rabbits (Oryctolagus cuniculus).ANIMALS: 6 juvenile female rabbits (n = 5 treatment and 1 control).METHODS: An ultrafiltration probe and CSBs were placed SC in 6 rabbits (n = 5 for FF CSBs and 1 for control CSBs). Plasma (3, 6, 12, 24, and 48 hours and 7, 14, and 21 days) and ISF (daily for 21 days) samples were collected, and FF was measured by HPLC for ...
Source: American Journal of Veterinary Research - May 14, 2024 Category: Veterinary Research Authors: Megan Partyka Stephen Divers Crisanta Cruz-Espindola Alisia A W Weyna Nicole L Gottdenker Laura Burns Kelsey Trumpp Dawn M Boothe Source Type: research

Care, connection, and social distancing: The challenges of baby loss during the COVID-19 pandemic in Aotearoa New Zealand
CONCLUSION: Social isolation is an added challenge for parents experiencing baby loss during a pandemic, which may be mitigated by flexible and compassionate care from healthcare professionals, especially continuity of care midwives.PMID:38744163 | DOI:10.1016/j.wombi.2024.101622 (Source: Women Birth)
Source: Women Birth - May 14, 2024 Category: Midwifery Authors: Billie F Bradford Robin S Cronin Tosin Popoola Nicola Bright Sergio A Silverio Source Type: research

Transgender and gender diverse people with endometriosis: A perspective on affirming gynaecological care
Womens Health (Lond). 2024 Jan-Dec;20:17455057241251974. doi: 10.1177/17455057241251974.ABSTRACTTransgender and gender diverse people presumed female at birth experience gynaecological conditions, such as chronic pelvic pain at elevated rates, estimated to impact between 51% and 72% of this population, compared to rates of up to 26.6% in cisgender women. The negative impact of these conditions is likely amplified due to limited access to safe and affirming healthcare. Despite this high prevalence rate, there is limited research investigating the prevalence, presentation or management options for trans and gender diverse pe...
Source: Pain Physician - May 14, 2024 Category: Anesthesiology Authors: Sam Jeffrey Louis Ashton Tania Ferfolja Mike Armour Source Type: research

Cardiovascular outcomes for people hospitalised with COVID-19 in Australia, and the effect of vaccination: an  observational cohort study
CONCLUSIONS: Although troponin levels were elevated in a considerable proportion of people hospitalised with COVID-19, clinical cardiovascular events were infrequent, and their likelihood was not influenced by vaccination. COVID-19 vaccination, however, was associated with reduced likelihood of in-hospital death and intubation.TRIAL REGISTRATION: Australian and New Zealand Clinical Trials Registry, ACTRN12620000486921 (prospective).PMID:38741458 | DOI:10.5694/mja2.52307 (Source: Medical Journal of Australia)
Source: Medical Journal of Australia - May 14, 2024 Category: General Medicine Authors: Hari P Sritharan Kunwardeep S Bhatia William van Gaal Leonard Kritharides Clara K Chow Ravinay Bhindi Source Type: research

Cardiovascular outcomes for people hospitalised with COVID-19 in Australia, and the effect of vaccination: an  observational cohort study
CONCLUSIONS: Although troponin levels were elevated in a considerable proportion of people hospitalised with COVID-19, clinical cardiovascular events were infrequent, and their likelihood was not influenced by vaccination. COVID-19 vaccination, however, was associated with reduced likelihood of in-hospital death and intubation.TRIAL REGISTRATION: Australian and New Zealand Clinical Trials Registry, ACTRN12620000486921 (prospective).PMID:38741458 | DOI:10.5694/mja2.52307 (Source: Med J Aust)
Source: Med J Aust - May 14, 2024 Category: General Medicine Authors: Hari P Sritharan Kunwardeep S Bhatia William van Gaal Leonard Kritharides Clara K Chow Ravinay Bhindi Source Type: research

Plasma and interstitial fluid antibiotic levels of subcutaneously implanted compounded florfenicol calcium sulfate beads in New Zealand White rabbits (Oryctolagus cuniculus)
Am J Vet Res. 2024 May 18:1-10. doi: 10.2460/ajvr.24.02.0044. Online ahead of print.ABSTRACTOBJECTIVE: To determine antibiotic levels in plasma and interstitial fluid (ISF) after SC placement of compounded florfenicol (FF) calcium sulfate beads (CSBs) in New Zealand White rabbits (Oryctolagus cuniculus).ANIMALS: 6 juvenile female rabbits (n = 5 treatment and 1 control).METHODS: An ultrafiltration probe and CSBs were placed SC in 6 rabbits (n = 5 for FF CSBs and 1 for control CSBs). Plasma (3, 6, 12, 24, and 48 hours and 7, 14, and 21 days) and ISF (daily for 21 days) samples were collected, and FF was measured by HPLC for ...
Source: American Journal of Veterinary Research - May 14, 2024 Category: Veterinary Research Authors: Megan Partyka Stephen Divers Crisanta Cruz-Espindola Alisia A W Weyna Nicole L Gottdenker Laura Burns Kelsey Trumpp Dawn M Boothe Source Type: research

Care, connection, and social distancing: The challenges of baby loss during the COVID-19 pandemic in Aotearoa New Zealand
CONCLUSION: Social isolation is an added challenge for parents experiencing baby loss during a pandemic, which may be mitigated by flexible and compassionate care from healthcare professionals, especially continuity of care midwives.PMID:38744163 | DOI:10.1016/j.wombi.2024.101622 (Source: Women Birth)
Source: Women Birth - May 14, 2024 Category: Midwifery Authors: Billie F Bradford Robin S Cronin Tosin Popoola Nicola Bright Sergio A Silverio Source Type: research

Plasma and interstitial fluid antibiotic levels of subcutaneously implanted compounded florfenicol calcium sulfate beads in New Zealand White rabbits (Oryctolagus cuniculus)
Am J Vet Res. 2024 May 18:1-10. doi: 10.2460/ajvr.24.02.0044. Online ahead of print.ABSTRACTOBJECTIVE: To determine antibiotic levels in plasma and interstitial fluid (ISF) after SC placement of compounded florfenicol (FF) calcium sulfate beads (CSBs) in New Zealand White rabbits (Oryctolagus cuniculus).ANIMALS: 6 juvenile female rabbits (n = 5 treatment and 1 control).METHODS: An ultrafiltration probe and CSBs were placed SC in 6 rabbits (n = 5 for FF CSBs and 1 for control CSBs). Plasma (3, 6, 12, 24, and 48 hours and 7, 14, and 21 days) and ISF (daily for 21 days) samples were collected, and FF was measured by HPLC for ...
Source: American Journal of Veterinary Research - May 14, 2024 Category: Veterinary Research Authors: Megan Partyka Stephen Divers Crisanta Cruz-Espindola Alisia A W Weyna Nicole L Gottdenker Laura Burns Kelsey Trumpp Dawn M Boothe Source Type: research

A CXCR3-Activating Peptide Increases Tear Break Up Time and Corrects Corneal haze in a Rabbit Model of Environmental Dry Eye
CONCLUSIONS: The treatment of environmental DED/KCS with a peptide that activates CXCR3 improved tear quality and reversed corneal pathology by promoting tear stability and likely dampening the corneal inflammation, while not affecting aqueous volume of the tears.PMID:38736523 | PMC:PMC11086663 | DOI:10.26502/fjppr.094 (Source: Cell Research)
Source: Cell Research - May 13, 2024 Category: Cytology Authors: Alan Wells Yadong Wang Hanshuang Shao Peri Sohnen Shivalingappa K Swamynathan Source Type: research

Changes and significance of the fibrinolytic system following two pulmonary thromboembolisms in a rabbit model
In this study, we examined the changes in the fibrinolytic system in a rabbit model of two acute pulmonary thromboembolisms (PTE). Fourteen healthy adult New Zealand white rabbits were divided into three groups: the single PTE group (five rabbits), the double PTE group (five rabbits), and the control group (four rabbits). A rabbit model of acute pulmonary embolism was established, and immunohistochemistry and polymerase chain reaction (PCR) were performed on tissue plasminogen activator (t-PA), plasminogen activator inhibitor-1 (PAI-1) in plasma, and pulmonary embolism tissue. Plasma results: 1) t-PA levels: one hour follo...
Source: Journal of Physiology and Pharmacology - May 13, 2024 Category: Drugs & Pharmacology Authors: D-C Liu B Duan M-N Zhao L Wu Y-Z Cao N-B Liu Z Xue Z-H He J Mi Source Type: research