Interview with Stefany Shaheen: Revolutionizing diabetes care through cell therapies
I had the extraordinary opportunity to chat with Stefany Shaheen, the Chief Strategy Officer of Advanced Regenerative Manufacturing Institute (ARMI) and BioFab USA, about the transformative potential of cell therapies for individuals living with diabetes. Stefany shared her remarkable journey, insights on cell therapies’ current status, approval challenges, and how the diabetes community can contribute to advancing research in this field. A few months before this discussion with Stefany, I had the opportunity to hear Dean Kamen speak at the recent ...
Source: Scott's Diabetes Blog - April 1, 2024 Category: Endocrinology Authors: Scott K. Johnson Tags: Blog Posts Source Type: blogs

Fight Aging! Newsletter, March 25th 2024
This study also reports the expansion of satellite cells in human muscle with CR. This finding is critical to suggest translational relevance to the rodent data observed for more than a decade. Moreover, the increased expression of the plasminogen receptor Plg-RKT observed on human satellite cells during CR provided additional support for the theory that our rodent model is relevant to human biology. « Back to Top Interesting Insight into the Relationship Between TP53, Telomerase, and Telomere Length https://www.fightaging.org/archives/2024/03/interesting-insight-into-the-relationship-between-t...
Source: Fight Aging! - March 24, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Low Socioeconomic Status Correlates with Raised Dementia Risk
It is well known that low socioeconomic status correlates with a raised risk of age-related disease and mortality, though it is challenging to determine which of the possible causes are in fact more or less important. A web of correlations are linked to socioeconomic status: intelligence, access to medical services, education, personality traits, lifestyle choices, and more. Here the focus of the study is on location of residence as a marker of socioeconomic status, and in this context it is interesting to note the studies that have compared the differences in particulate air pollution versus mortality in wealthier versus ...
Source: Fight Aging! - March 21, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

It Seems This Has Become A Complex Public Health Emergency Under Our Very Noses.
This appeared last week and frankly reveals a public health disaster …. The vape ban has utterly failed. What now? Vaping rates have exploded, organised crime controls the trade, and Australia stands on the brink of a public health disaster. Is it time we followed New Zealand ’s lead? By Natasha Robinson March 15, 2024 Australia stands on the brink of a public health disaster. The failure to (Source: Australian Health Information Technology)
Source: Australian Health Information Technology - March 17, 2024 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

Some Views On Digital Health Interoperability From One Of Our Experts
This appeared in New Zealand and I felt it needed some OZ exposure: My View: Interoperability is a team sport Monday, 19 February 2024   VIEW - Grahame Grieve, FHIR product director I started working on FHIR (Fast Healthcare Interoperability Resources) because I believe in better health outcomes and that healthcare has broken processes. As well as being a technical standard, FHIR (Source: Australian Health Information Technology)
Source: Australian Health Information Technology - February 28, 2024 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

Living with pain is social: The Chronic Pain Couple book review
Over the past year or so I’ve kept returning to ‘the social’ part of our multifactorial pain experience.* Pain can be extraordinarily isolating, and our current sociopolitical emphasis maintains a focus on ‘what the individual should do.’ In New Zealand, our accident compensation legislation is a no-fault, 24/7 everywhere, all-the-time innovation but it falls short in critical areas. One is the continued focus on ‘physical findings’ to validate a diagnosis (and to show that the resultant impact on an individual is entirely due to a personal injury caused by accident), and the other...
Source: HealthSkills Weblog - February 25, 2024 Category: Anesthesiology Authors: BronnieLennoxThompson Tags: Chronic pain Coping strategies Professional topics Health pain management Therapeutic approaches Source Type: blogs

Fight Aging! Newsletter, February 26th 2024
In conclusion, mTORC1 signaling contributes to the ISC fate decision, enabling regional control of intestinal cell differentiation in response to nutrition. « Back to Top Reviewing the Development of Senotherapeutics to Treat Aging https://www.fightaging.org/archives/2024/02/reviewing-the-development-of-senotherapeutics-to-treat-aging/ Senescent cells accumulate with age and contribute meaningfully to chronic inflammation and degenerative aging. Destroying these cells produces rapid and sizable reversal of age-related diseases in mice, demonstrating that the presence of senescence cells ...
Source: Fight Aging! - February 25, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

An Update on Kimer Med, Improving on the DRACO Antiviral Technology and Moving Towards the Clinic
The state of anti-viral therapies isn't that great, all things considered. Technology has not yet advanced to the point at which a viral infection can be simply shut down, as is the case for near all bacterial infections. The present anti-viral drugs are either vaccines (useful!) or merely shift the odds somewhat by interfering in some part of the viral life cycle, but nowhere near as effectively as desired. Many persistent viral infections are thought to contribute meaningfully to forms of age-related dysfunction, and there is too little that can be done about that at the present time. This landscape is one of the ...
Source: Fight Aging! - February 23, 2024 Category: Research Authors: Reason Tags: Longevity Industry Source Type: blogs

The difficult balance between evidence-based healthcare … and person-centred self-management
For decades I’ve been an advocate for evidence-based healthcare because the alternative is ’eminence-based healthcare’ (for healthcare, read ‘medicine’ in the original!). Eminence-based healthcare is based on opinion and leverages power based on a hierarchy from within biomedicine (read this for more!). EBHC appealed because in clinical practice I heard the stories of people living with chronic pain who had experienced treatment after treatment of often invasive and typically unhelpful therapies, and EBHC offered a sifting mechanism to filter out the useless from the useful. Where has EBHC...
Source: HealthSkills Weblog - February 18, 2024 Category: Anesthesiology Authors: BronnieLennoxThompson Tags: Chronic pain Clinical reasoning Coping strategies Pain conditions Professional topics Research Science in practice pain management Therapeutic approaches Source Type: blogs

Self-management skills we don ’ t often discuss
I’m back from my summer break (I’m in Aotearoa/New Zealand – we shut down over Christmas/New Year just like the US and UK do over July/August!), and I want to begin with a cracker of a topic: medication management! Now I am not a prescriber. I don’t hold any ability to write prescriptions of any kind, not even exercise ;-). Yet most of the people I’ve seen in clinical practice have started their journey living with pain by being prescribed medications. All medications have side effects, true effects (well… maybe), adverse effects, and the human factor: taking them in the way that o...
Source: HealthSkills Weblog - January 14, 2024 Category: Anesthesiology Authors: BronnieLennoxThompson Tags: Chronic pain Coping strategies Research Science in practice pain management self-management Therapeutic approaches Source Type: blogs

Consider Bypassing Your Health Insurance to Afford Certain Type 1 Diabetes-Related Medicines and Supplies
Since it ' s January (a new year), and about half of all Americans with employer-sponsored healthcare insurance plans have some deductibles to satisfy before their healthcare insurance really kicks-in to cover much of anything and deductibles reset on January 1, I thought perhaps this might be a good time to write about my own experience with high-deductible insurance plans and some intelligent work-arounds which I ' ve discovered to deal with those. Who knows? You might (as I did) find you actually like using a particular brand or variety of insulin which is not " preferred " by your insurance ' s PBM, or maybe you f...
Source: Scott's Web Log - January 11, 2024 Category: Endocrinology Tags: type 1 diabetes 2024 bypass insurance manufacturer coupons PBM ' PBMs unbranded insulin Source Type: blogs

Volpara Health Enters Agreement to be Acquired by Lunit, Inc.
Volpara Health Technologies (Volpara), a global leader in software for the early detection of breast cancer, is pleased to announce it has entered into an agreement to be acquired by Lunit Inc. Under the terms of the agreement, Lunit would acquire all shares of Volpara stock for A$1.15 per share in cash, representing a 47.4% premium to the Company’s closing stock price on December 13, 2023. The transaction is expected to accelerate Volpara’s ability to serve its purpose of saving families from cancer. With the support of Lunit’s in-house radiologists and complementary technologies, Volpara’s repos...
Source: EMR and HIPAA - January 8, 2024 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT Health IT Acquisitions Healthcare M&A Lunit Lunit Inc. Teri Thomas Volpara Volpara Health Technologies Source Type: blogs

Lessons from historical drug prohibitions
New Zealand just rescinded its ban on tobacco smoking at the same time that Donald Trump just suggested the death penalty could cure the drug problem. What did New Zealand learn? And how has drug prohibition worked out in the past? In 1511, the governor of Mecca, Khair Beg, had a serious problem. A powerful Read more… Lessons from historical drug prohibitions originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - December 1, 2023 Category: General Medicine Authors: Tags: Conditions Public Health & Policy Source Type: blogs

Health Care Providers ’ Early Experiences of Assisted Dying in Aotearoa New Zealand: An Evolving Clinical Service
Jeanne Snelling (University of Otago), Jessica E. Young (Victoria University of Wellington), Sophie Beaumont (Victoria University of Wellington), Kate Diesfeld (Auckland University of Technology), et al., Health Care Providers ’ Early Experiences of Assisted Dying in Aotearoa New Zealand: An Evolving... (Source: HealthLawProf Blog)
Source: HealthLawProf Blog - November 26, 2023 Category: Medical Law Authors: Katharine Van Tassel Source Type: blogs

Invasive species in the UK
Invasive species, a term referring to non-native species introduced to new environments, often establish self-sustaining populations with negative impacts on local ecosystems, economies, or human health. These invaders, encompassing plants, animals, fungi, or microorganisms (refer to the foot of this article for examples), typically arrive due to human activities such as trade, travel, or intentional release. In rare cases, invasive species might reach the UK through natural avenues, such as animal migration or wind dispersal. Climate change exacerbates the situation, creating new ecological niches due to shifts in tempera...
Source: David Bradley Sciencebase - Songs, Snaps, Science - November 10, 2023 Category: Science Authors: David Bradley Tags: Biology Environment Science Source Type: blogs