Remote or in-clinic? The effect of service delivery mode on hearing aid output: study protocol for a double-blinded, randomised trial in adults with mild to moderate sensorineural hearing loss
ConclusionsThis study will inform the development of best practice guidelines for remote hearing aid fittings. If no clinically significant differences are found between in-clinic and remote fit hearing aids, it has the potential to expand teleaudiology initiatives.Trial registrationAustralian New Zealand Clinical Trial Registry,ACTRN12623000028606p.  Date of registration: 12 January 2023. (Source: Trials)
Source: Trials - April 12, 2024 Category: Research Source Type: clinical trials

STRatIfication of Vulvar SCC by HPV and p53 Status to Guide Excision
Conditions: Vulvar Squamous Cell Carcinoma Interventions: Procedure: Surgery; Other: Active Surveillance Sponsors: Canadian Cancer Trials Group; Australia New Zealand Gynaecological Oncology Group Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 10, 2024 Category: Research Source Type: clinical trials

Australasian Malignant PLeural Effusion (AMPLE)-4 trial: study protocol for a multi-centre randomised trial of topical antibiotics prophylaxis for infections of indwelling pleural catheters
DiscussionResults from this trial will determine the efficacy of mupirocin prophylaxis in patients who require IPC for MPE. It will provide data on infection rates, microbiology, and potentially infection pathways associated with IPC-related infections.Ethics and disseminationSir Charles Gairdner and Osborne Park Health Care Group Human Research Ethics Committee has approved the study (RGS0000005920). Results will be published in peer-reviewed journals and presented at scientific conferences.Trial registrationAustralia New Zealand Clinical Trial Registry ACTRN12623000253606. Registered on 9 March 2023. (Source: Trials)
Source: Trials - April 10, 2024 Category: Research Source Type: clinical trials

The effects of telerehabilitation in adults with complex biventricular congenital heart conditions: protocol for a multi-centre, randomised controlled trial —CH-FIT
DiscussionIf found to be efficacious, telerehabilitation may be an alternative option for delivering exercise, improving health outcomes, and increasing accessibility to exercise programmes. Efficacy data is required to quantify the clinical significance of this delivery mode of exercise.Trial registrationACTRN12622000050752Trial registration date: 17 January 2022Trial registration URL:https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=382635&showOriginal=true&isReview=trueTrial registry name: Australian and New Zealand Clinical Trials Registry (Source: Trials)
Source: Trials - April 5, 2024 Category: Research Source Type: clinical trials

Developing an Utstein-style Danish Drowning Registry: Nationwide Fatal and Nonfatal Drowning Data Since 2016
Conditions: Drowning; Drowning, Near; Drowning; Asphyxia; Drowning and Nonfatal Submersion; Drowning or Immersion of Unknown Intent; Drowning and Submersion, Undetermined Intent; Drowning and Submersion While in Bath-Tub; Drowning and Submersion While in Natural Water; Drowning and Submersion While in Swimming-Pool Interventions: Other: Drowning Sponsors: Prehospital Center, Region Zealand Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 28, 2024 Category: Research Source Type: clinical trials

Patients Treated by the Danish Emergency Medical Services Following Non-drowning Water Rescues From 2016 to 2023
Conditions: Drowning; Drowning, Near; Submersion; Submersion - Accidental; Submersion or Drowning Due to Being Washed Overboard; Submersion or Drowning Due to Being Thrown Overboard; Submersion or Drowning Due to Ship Sinking, Water Skier Injured; Submersion or Drowning Due to Boat Submerging, Swimmer Injured; Submersion or Drowning Due to Boat Overturning, Swimmer Injured; Submersion or Drowning Due to Boat Submerging, Water Skier Injured; Submersion or Drowning Due to Fall From Gangplank, Swimmer Injured; Submersion or Drowning Due to Ship Sinking, Docker or Stevedore Injured; Submersion or Drowning Due to Fall Overboard...
Source: ClinicalTrials.gov - March 25, 2024 Category: Research Source Type: clinical trials

In Situ Simulation Training in Lifeguard Organisations
Conditions: Drowning; Drowning, Near; Drowning and Nonfatal Submersion; Drowning/Submersion; Drowning and Submersion While in Natural Water Interventions: Other: In situ simulation assessment Sponsors: Prehospital Center, Region Zealand Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 20, 2024 Category: Research Source Type: clinical trials

Drowning Incidents Treated by the Danish SAR Helicopters
Conditions: Drowning; Drown; Drowning; Anoxia; Drowning, Near; Drowning and Nonfatal Submersion; Drowning or Immersion of Unknown Intent; Drowning and Submersion, Undetermined Intent; Drowning and Submersion While in Natural Water; Drowning and Submersion Due to Sailboat Sinking; Drowning and Submersion Due to Fall Off Ship Interventions: Other: Drowning incident Sponsors: Prehospital Center, Region Zealand Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 20, 2024 Category: Research Source Type: clinical trials

The Effect of Continuous Glucose Monitoring in Surgical Patients With Diabetes.
Conditions: Diabetes Mellitus; Dysglycemia; Perioperative Complication Interventions: Device: Dexcom G7 Continuous Glucose Monitoring (CGM) System (G7) Sponsors: Christian S. Meyhoff; Rigshospitalet, Denmark; Steno Diabetes Center Copenhagen; Zealand University Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 15, 2024 Category: Research Source Type: clinical trials

Drowning Incidents in Danish Harbours
Conditions: Drowning; Drown; Drowning; Anoxia; Drowning, Near; Drowning; Asphyxia; Drowning and Nonfatal Submersion; Drowning or Immersion of Unknown Intent; Drowning and Submersion, Undetermined Intent; Drowning and Submersion While in Natural Water; Drowning and Submersion Due to Sailboat Sinking; Drowning and Submersion Due to Fall Off Ship Interventions: Other: Drowning Sponsors: Prehospital Center, Region Zealand Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 15, 2024 Category: Research Source Type: clinical trials

Primary or Secondary Drowning
Conditions: Drowning; Drowning; Anoxia; Drowning, Near; Drowning in Swimming Pool; Drowning; Asphyxia; Drowning/Diving/SCUBA Accident; Drowning or Immersion of Unknown Intent; Drowning and Submersion, Undetermined Intent; Drowning and Submersion While in Bath-Tub; Drowning and Submersion While in Natural Water; Drowning and Submersion Due to Sailboat Sinking; Drowning and Submersion Due to Fall Off Ship; Drowning and Submersion While in Swimming-Pool Interventions: Other: Drowning Sponsors: Prehospital Center, Region Zealand Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 15, 2024 Category: Research Source Type: clinical trials

The Emergency Call on Drowning
Conditions: Drowning; Drowning; Anoxia; Drowning, Near; Drowning; Asphyxia; Drowning and Nonfatal Submersion; Drowning or Immersion of Unknown Intent; Drowning and Submersion, Undetermined Intent; Drowning and Submersion While in Bath-Tub; Drowning and Submersion While in Natural Water; Drowning and Submersion Due to Sailboat Sinking; Drowning and Submersion Due to Fall Off Ship; Drowning and Submersion While in Swimming-Pool Interventions: Other: Drowning-related OHCA; Other: Drowning-related non-OHCA Sponsors: Prehospital Center, Region Zealand Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 15, 2024 Category: Research Source Type: clinical trials

Using Machine Learning to Optimise the Danish Drowning Formula
Conditions: Drowning; Drowning and Submersion While in Bath-Tub; Drowning and Submersion While in Natural Water; Drowning and Submersion While in Swimming-Pool; Drowning and Submersion Due to Fall Off Ship; Drowning and Nonfatal Submersion; Drowning, Near; Drowning; Asphyxia Interventions: Other: Drowning incident Sponsors: Prehospital Center, Region Zealand Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 15, 2024 Category: Research Source Type: clinical trials

The efficacy and safety of deucravacitinib compared to methotrexate, in patients with vulvar lichen planus who have failed topical therapy with potent corticosteroids: a study protocol for a single-centre double-blinded randomised controlled trial
DiscussionHigh-quality evidence guiding the management of women with VLP is lacking. Once completed, this will be the first double-blinded RCT to compare systemic treatments in VLP. The results of this study will provide valuable, high-quality data to guide second-line therapy options for VLP that is recalcitrant to potent topical corticosteroids.Trial registrationAustralian New Zealand Clinical Trials Registry ACTRN12623000682640. Registered on 26 June 2023. (Source: Trials)
Source: Trials - March 12, 2024 Category: Research Source Type: clinical trials

Lymphovenous Anastomosis for Breast Cancer Lymphedema
Conditions: Lymphedema; Lymphedema Arm; Breast Cancer Lymphedema; Lymphedema, Secondary; Lymphedema; Surgical; Lymphedema of Upper Limb; Lymphedema, Breast Cancer Interventions: Procedure: Lymphovenous anastomosis (LVA) Sponsors: Odense University Hospital; Vejle Hospital; Zealand University Hospital; Herlev and Gentofte Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 8, 2024 Category: Research Source Type: clinical trials