Mixed Epithelial Carcinoma Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Research

Malignant mixed epithelial and stromal tumor of the kidney with rhabdomyosarcomatous transformation presenting with gross hematuria
Proc (Bayl Univ Med Cent). 2022 Jul 5;35(6):837-839. doi: 10.1080/08998280.2022.2090788. eCollection 2022.ABSTRACTMalignant rhabdomyosarcoma associated with mixed epithelial and stromal tumor of the kidney (MESTK) is an exceptionally rare clinical phenomenon, with only two reported cases. Here, we describe the case of a middle-aged Middle Eastern woman with a left renal mass diagnosed as malignant MESTK with rhabdomyosarcomatous transformation. The patient initially presented with gross hematuria and was found to have a heterogenous 6.3 × 4.0 cm left renal mass, initially suspected to be renal cell carcinoma. She underwen...
Source: Baylor University Medical Center Proceedings - October 28, 2022 Category: Universities & Medical Training Authors: Soroush Shahrokh Maryam Abolhasani Reza Kaffash Nayeri Source Type: research

Peripheral dentinogenic ghost cell tumor: case report
Peripheral dentinogenic ghost cell tumor (DGCT) is a rare benign mixed epithelial and mesenchymal odontogenic neoplasm, with approximately 52 cases reported in the literature. A 48-year-old woman was referred for evaluation of a painless, slow-growing swelling in the mandible caused by a removable denture that evolved over 1 year. Her medical history was unremarkable. Intraoral examination showed a pinkish, firm nodule, with erythematous areas, in the left mandibular alveolar ridge. Panoramic radiographic examination revealed no signs of bone involvement. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - August 17, 2022 Category: ENT & OMF Authors: Christany Rodrigues Ferreira, Marjhory Fernandes De Moura, H élder Domiciano Dantas Martins, Tácio Candeia Lyra, José Wilson Noleto Ramos, Pollianna Muniz Alves, Cassiano Francisco Weege Nonaka Source Type: research

Diagnosis and Treatment of a Mixed Epithelial Stromal Tumor of the Seminal Vesicle: A Systematic Review
: To perform a systematic review of mixed epithelial stromal tumor (MEST) of the seminal vesicle (SV) to characterize the diagnosis and treatment of this rare condition. (Source: Urology)
Source: Urology - February 25, 2022 Category: Urology & Nephrology Authors: Mustufa Babar, Jubin Matloubieh, Eric Macdonald, Jinrong Cheng, Ahmed Aboumohamed, Kara Watts Tags: Review Source Type: research

IL ‐34 in hepatoblastoma cells potentially promote tumor progression via autocrine and paracrine mechanisms
In conclusion, IL-34 expression in embryonal components may induce macrophage chemotaxis in a paracrine manner, and tumor cell proliferation and chemoresistance in an autocrine manner. IL-34 is a potential therapeutic target for hepatoblastoma. (Source: Cancer Medicine)
Source: Cancer Medicine - February 8, 2022 Category: Cancer & Oncology Authors: Tomoaki Irie, Daiki Yoshii, Yoshihiro Komohara, Yukio Fujiwara, Masashi Kadohisa, Masaki Honda, Shinya Suzu, Toshiharu Matsuura, Kenichi Kohashi, Yoshinao Oda, Taizo Hibi Tags: RESEARCH ARTICLE Source Type: research

Case report: two rare cases of mixed epithelial and stromal tumor of the kidney and a review of the literature
We report one rare case of MESTK, which was diagnosed in a 30-year-old woman. A computed tomography (CT) scan revealed one well-defined, uneven mass in the left kidney. The tissue obtained by fine-needle aspiration showed relatively homogeneous cells. Renal cell carcinoma could not be excluded, and left complete nephrectomy was performed, according to the patient's wishes. Another case of MESTK we present here was diagnosed in an 18-year-old male adolescent, who did not have a history of estrogen treatment, with estrogen treatment seen rarely in the clinical setting. Renal cell carcinoma was suspected, and a left partial n...
Source: Cell Research - February 4, 2022 Category: Cytology Authors: Huangwei Huang Xuewen Jiang Benkang Shi Gang Yin Jianfeng Cui Changsheng Guo Chunxiao Yu Hui Meng Source Type: research

Molecular Analysis of an Intestinal Neuroendocrine/Non-neuroendocrine Neoplasm (MiNEN) Reveals MLH1 Methylation-driven Microsatellite Instability and a Monoclonal Origin: Diagnostic and Clinical Implications
Mixed neuroendocrine/non-neuroendocrine neoplasms (MiNEN) are rare mixed epithelial neoplasms in which a neuroendocrine component is combined with a non-neuroendocrine component. Here, we provide the clinical, pathologic, and molecular report of a 73-year-old-man presenting with an intestinal MiNEN. The lesion was composed of a well-differentiated G3 neuroendocrine tumor and a colloid adenocarcinoma. The molecular characterization was performed using a multigene next-generation sequencing panel. The neoplasm displayed microsatellite instability due to MLH1 promoter methylation. The extended molecular profile documented the...
Source: Applied Immunohistochemistry and Molecular Morphology - February 1, 2022 Category: Chemistry Tags: Research Articles Source Type: research

Report of two primary renal tumors with myxoid features. Differential diagnosis between benign and malignant entities
Pathologica. 2021 Dec;113(6):427-435. doi: 10.32074/1591-951X-180.ABSTRACTRenal mesenchymal neoplasms are rare entities which can have a benign or a malignant behavior. Herein we describe two renal mesenchymal tumors with myxoid stroma, investigating the wide spectrum of differential diagnosis. With our first case we considered some benign entities such as myxoma, myxoid leiomyoma, and mixed epithelial and stromal tumor; with our second case we considered some sarcomas with myxoid features such as myxofibrosarcoma, low-grade fibromyxoid sarcoma, dedifferentiated liposarcoma, and myxoid liposarcoma. During the diagnostic pr...
Source: Pathologica - January 2, 2022 Category: Pathology Authors: Adele Fioravanzo Guido Martignoni Matteo Brunelli Diego Segala Francesco Erdini Source Type: research

Spectrum of incipient (or precursor) lesions in the mucosa of the seminal vesicles
Pathol Res Pract. 2021 Dec 11;229:153737. doi: 10.1016/j.prp.2021.153737. Online ahead of print.ABSTRACTThe seminal vesicle (SV) mucosa can show epithelial and stromal tumors. The epithelial tumors include both cystadenoma and carcinomas, adenocarcinoma being the most common. Squamous carcinoma may arise in the SV (1). Rarely mixed epithelial and stromal tumors (MESTs) can occur. Incipient lesions, i.e., primary precursor or preinvasive lesions giving rise to such tumors in the mucosa of the SVs, have been observed in anecdotal cases.PMID:34952428 | DOI:10.1016/j.prp.2021.153737 (Source: Pathology, Research and Practice)
Source: Pathology, Research and Practice - December 24, 2021 Category: Pathology Authors: Alessia Cimadamore Liang Cheng Antonio Lopez-Beltran Marina Scarpelli Rodolfo Montironi Source Type: research

Imaging findings of uterine adenosarcoma with sarcomatous overgrowth: two case reports, emphasizing restricted diffusion on diffusion weighted imaging
Adenosarcoma is classified as a mixed epithelial and mesenchymal tumor composed of a benign epithelial component and a malignant stromal component. The stromal component in adenosarcoma is usually low grade, a... (Source: BMC Women's Health)
Source: BMC Women's Health - December 16, 2021 Category: OBGYN Authors: Go Nakai, Hiroki Matsutani, Takashi Yamada, Masahide Ohmichi, Kazuhiro Yamamoto and Keigo Osuga Tags: Case report Source Type: research