A case of infection-induced thrombotic thrombocytopenic purpura
CONCLUSION: TTP is an acute severe disease with complex etiology, abrupt onset, and dangerous conditions. In this patient with TTP, an important cause of the disease may have been an acute gastrointestinal infection. The plasma examination in another hospital revealed positive results for ADAMTS13 inhibitors, providing strong evidence for the diagnosis of this case. Multiple plasma exchanges and glucocorticoids yielded favorable treatment results and were critical measures of successful treatment of TTP.PMID:37182863 | DOI:10.3233/CH-231784 (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - May 14, 2023 Category: Hematology Authors: Shaohua Cui Chaoyue Liang Lixia Geng Source Type: research

A case of infection-induced thrombotic thrombocytopenic purpura
CONCLUSION: TTP is an acute severe disease with complex etiology, abrupt onset, and dangerous conditions. In this patient with TTP, an important cause of the disease may have been an acute gastrointestinal infection. The plasma examination in another hospital revealed positive results for ADAMTS13 inhibitors, providing strong evidence for the diagnosis of this case. Multiple plasma exchanges and glucocorticoids yielded favorable treatment results and were critical measures of successful treatment of TTP.PMID:37182863 | DOI:10.3233/CH-231784 (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - May 14, 2023 Category: Hematology Authors: Shaohua Cui Chaoyue Liang Lixia Geng Source Type: research

A case of infection-induced thrombotic thrombocytopenic purpura
CONCLUSION: TTP is an acute severe disease with complex etiology, abrupt onset, and dangerous conditions. In this patient with TTP, an important cause of the disease may have been an acute gastrointestinal infection. The plasma examination in another hospital revealed positive results for ADAMTS13 inhibitors, providing strong evidence for the diagnosis of this case. Multiple plasma exchanges and glucocorticoids yielded favorable treatment results and were critical measures of successful treatment of TTP.PMID:37182863 | DOI:10.3233/CH-231784 (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - May 14, 2023 Category: Hematology Authors: Shaohua Cui Chaoyue Liang Lixia Geng Source Type: research

A case of infection-induced thrombotic thrombocytopenic purpura
CONCLUSION: TTP is an acute severe disease with complex etiology, abrupt onset, and dangerous conditions. In this patient with TTP, an important cause of the disease may have been an acute gastrointestinal infection. The plasma examination in another hospital revealed positive results for ADAMTS13 inhibitors, providing strong evidence for the diagnosis of this case. Multiple plasma exchanges and glucocorticoids yielded favorable treatment results and were critical measures of successful treatment of TTP.PMID:37182863 | DOI:10.3233/CH-231784 (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - May 14, 2023 Category: Hematology Authors: Shaohua Cui Chaoyue Liang Lixia Geng Source Type: research

P95 Plasma exchange for HELLP syndrome complicated by persistent microangiopathic haemolytic anaemia resulting in a rapid recovery of renal function
(Source: International Journal of Obstetric Anesthesia)
Source: International Journal of Obstetric Anesthesia - May 1, 2023 Category: Anesthesiology Authors: P. Wyatt, M. Aukland, B. Anderson, S. Fletcher Source Type: research

Better late than never: Diagnosis of recurrent atypical hemolytic uremic syndrome
We present a case of a 50-year-old female who received her first kidney transplant from her mother at the age of 9 years. She experienced recurrent losses of transplants, and only after the loss of her fourth transplant did the diagnosis of aHUS become evident.PMID:37114491 | DOI:10.5414/CN111047 (Source: Clinical Nephrology)
Source: Clinical Nephrology - April 28, 2023 Category: Urology & Nephrology Authors: Sari Aaltonen Anne R äisänen-Sokolowski Kati Kaartinen Source Type: research

Better late than never: Diagnosis of recurrent atypical hemolytic uremic syndrome
We present a case of a 50-year-old female who received her first kidney transplant from her mother at the age of 9 years. She experienced recurrent losses of transplants, and only after the loss of her fourth transplant did the diagnosis of aHUS become evident.PMID:37114491 | DOI:10.5414/CN111047 (Source: Clinical Nephrology)
Source: Clinical Nephrology - April 28, 2023 Category: Urology & Nephrology Authors: Sari Aaltonen Anne R äisänen-Sokolowski Kati Kaartinen Source Type: research

Better late than never: Diagnosis of recurrent atypical hemolytic uremic syndrome
We present a case of a 50-year-old female who received her first kidney transplant from her mother at the age of 9 years. She experienced recurrent losses of transplants, and only after the loss of her fourth transplant did the diagnosis of aHUS become evident.PMID:37114491 | DOI:10.5414/CN111047 (Source: Clinical Nephrology)
Source: Clinical Nephrology - April 28, 2023 Category: Urology & Nephrology Authors: Sari Aaltonen Anne R äisänen-Sokolowski Kati Kaartinen Source Type: research

Better late than never: Diagnosis of recurrent atypical hemolytic uremic syndrome
We present a case of a 50-year-old female who received her first kidney transplant from her mother at the age of 9 years. She experienced recurrent losses of transplants, and only after the loss of her fourth transplant did the diagnosis of aHUS become evident.PMID:37114491 | DOI:10.5414/CN111047 (Source: Clinical Nephrology)
Source: Clinical Nephrology - April 28, 2023 Category: Urology & Nephrology Authors: Sari Aaltonen Anne R äisänen-Sokolowski Kati Kaartinen Source Type: research

A multicenter evaluation of the Technoscreen ADAMTS13 activity semi-quantitative screening test for thrombotic thrombocytopenic purpura diagnosis and exclusion
CONCLUSION: The Technoscreen assay appears to be a reliable screening test for ADAMTS13 activity to exclude TTP in routine clinical practice. However, the assay falsely identified ADAMTS13 deficiency in many cases, partially batch related, which mandates confirmation with a quantitative assay, as well as initial assessment of kits as 'fit for purpose' prior to use for patient testing.PMID:37078536 | DOI:10.1111/ijlh.14077 (Source: International Journal of Laboratory Hematology)
Source: International Journal of Laboratory Hematology - April 20, 2023 Category: Hematology Authors: Jared Stephenson Kent Chapman Soma Mohammed Diane Zebeljan Monica Ahuja Dea Donikian Leonardo Pasalic Penelope Motum Danny Hsu Timothy Brighton Emmanuel J Favaloro Source Type: research

A multicenter evaluation of the Technoscreen ADAMTS13 activity semi-quantitative screening test for thrombotic thrombocytopenic purpura diagnosis and exclusion
CONCLUSION: The Technoscreen assay appears to be a reliable screening test for ADAMTS13 activity to exclude TTP in routine clinical practice. However, the assay falsely identified ADAMTS13 deficiency in many cases, partially batch related, which mandates confirmation with a quantitative assay, as well as initial assessment of kits as 'fit for purpose' prior to use for patient testing.PMID:37078536 | DOI:10.1111/ijlh.14077 (Source: International Journal of Laboratory Hematology)
Source: International Journal of Laboratory Hematology - April 20, 2023 Category: Hematology Authors: Jared Stephenson Kent Chapman Soma Mohammed Diane Zebeljan Monica Ahuja Dea Donikian Leonardo Pasalic Penelope Motum Danny Hsu Timothy Brighton Emmanuel J Favaloro Source Type: research

A multicenter evaluation of the Technoscreen ADAMTS13 activity semi-quantitative screening test for thrombotic thrombocytopenic purpura diagnosis and exclusion
CONCLUSION: The Technoscreen assay appears to be a reliable screening test for ADAMTS13 activity to exclude TTP in routine clinical practice. However, the assay falsely identified ADAMTS13 deficiency in many cases, partially batch related, which mandates confirmation with a quantitative assay, as well as initial assessment of kits as 'fit for purpose' prior to use for patient testing.PMID:37078536 | DOI:10.1111/ijlh.14077 (Source: International Journal of Laboratory Hematology)
Source: International Journal of Laboratory Hematology - April 20, 2023 Category: Hematology Authors: Jared Stephenson Kent Chapman Soma Mohammed Diane Zebeljan Monica Ahuja Dea Donikian Leonardo Pasalic Penelope Motum Danny Hsu Timothy Brighton Emmanuel J Favaloro Source Type: research

A multicenter evaluation of the Technoscreen ADAMTS13 activity semi-quantitative screening test for thrombotic thrombocytopenic purpura diagnosis and exclusion
CONCLUSION: The Technoscreen assay appears to be a reliable screening test for ADAMTS13 activity to exclude TTP in routine clinical practice. However, the assay falsely identified ADAMTS13 deficiency in many cases, partially batch related, which mandates confirmation with a quantitative assay, as well as initial assessment of kits as 'fit for purpose' prior to use for patient testing.PMID:37078536 | DOI:10.1111/ijlh.14077 (Source: International Journal of Laboratory Hematology)
Source: International Journal of Laboratory Hematology - April 20, 2023 Category: Hematology Authors: Jared Stephenson Kent Chapman Soma Mohammed Diane Zebeljan Monica Ahuja Dea Donikian Leonardo Pasalic Penelope Motum Danny Hsu Timothy Brighton Emmanuel J Favaloro Source Type: research

A multicenter evaluation of the Technoscreen ADAMTS13 activity semi-quantitative screening test for thrombotic thrombocytopenic purpura diagnosis and exclusion
CONCLUSION: The Technoscreen assay appears to be a reliable screening test for ADAMTS13 activity to exclude TTP in routine clinical practice. However, the assay falsely identified ADAMTS13 deficiency in many cases, partially batch related, which mandates confirmation with a quantitative assay, as well as initial assessment of kits as 'fit for purpose' prior to use for patient testing.PMID:37078536 | DOI:10.1111/ijlh.14077 (Source: International Journal of Laboratory Hematology)
Source: International Journal of Laboratory Hematology - April 20, 2023 Category: Hematology Authors: Jared Stephenson Kent Chapman Soma Mohammed Diane Zebeljan Monica Ahuja Dea Donikian Leonardo Pasalic Penelope Motum Danny Hsu Timothy Brighton Emmanuel J Favaloro Source Type: research

Calcineurin Inhibitor-Induced Atypical Hemolytic Uremic Syndrome after Heart Transplantation
Calcineurin inhibitors (CNI) are the mainstay of immunosuppression after heart transplantation. Atypical hemolytic uremic syndrome (aHUS), defined as the constellation of microangiopathic hemolytic anemia, thrombocytopenia and renal dysfunction, is a rare complication of CNI use following solid organ transplantation. This is the first case series to describe the clinical features, treatment and outcomes of patients with CNI-induced aHUS after heart transplantation. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2023 Category: Transplant Surgery Authors: J. Patel, I. Mahana, P.H. Lam, M. Hofmeyer, S. Rao, A. Kadakkal, N. Afari-Armah, M. Krishnan, E. Molina, S. Najjar, F. Sheikh, M. Rodrigo, R. Gupta Tags: (490) Source Type: research