Upadacitinib in Rheumatoid Arthritis and Inadequate Response to Conventional Synthetic Disease-Modifying Antirheumatic Drugs: Efficacy and Safety Through 5 Years (SELECT-NEXT)
CONCLUSION: The 5-year benefit-risk profile for upadacitinib in RA remains favorable.PMID:38621793 | DOI:10.3899/jrheum.2023-1062 (Source: J Rheumatol)
Source: J Rheumatol - April 15, 2024 Category: Rheumatology Authors: Gerd R Burmester Filip Van den Bosch John Tesser Anna Shmagel Yanxi Liu Nasser Khan Heidi S Camp Alan Kivitz Source Type: research
Upadacitinib in Rheumatoid Arthritis and Inadequate Response to Conventional Synthetic Disease-Modifying Antirheumatic Drugs: Efficacy and Safety Through 5 Years (SELECT-NEXT)
CONCLUSION: The 5-year benefit-risk profile for upadacitinib in RA remains favorable.PMID:38621793 | DOI:10.3899/jrheum.2023-1062 (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 15, 2024 Category: Rheumatology Authors: Gerd R Burmester Filip Van den Bosch John Tesser Anna Shmagel Yanxi Liu Nasser Khan Heidi S Camp Alan Kivitz Source Type: research
Upadacitinib in Rheumatoid Arthritis and Inadequate Response to Conventional Synthetic Disease-Modifying Antirheumatic Drugs: Efficacy and Safety Through 5 Years (SELECT-NEXT)
CONCLUSION: The 5-year benefit-risk profile for upadacitinib in RA remains favorable.PMID:38621793 | DOI:10.3899/jrheum.2023-1062 (Source: J Rheumatol)
Source: J Rheumatol - April 15, 2024 Category: Rheumatology Authors: Gerd R Burmester Filip Van den Bosch John Tesser Anna Shmagel Yanxi Liu Nasser Khan Heidi S Camp Alan Kivitz Source Type: research
Upadacitinib in Rheumatoid Arthritis and Inadequate Response to Conventional Synthetic Disease-Modifying Antirheumatic Drugs: Efficacy and Safety Through 5 Years (SELECT-NEXT)
CONCLUSION: The 5-year benefit-risk profile for upadacitinib in RA remains favorable.PMID:38621793 | DOI:10.3899/jrheum.2023-1062 (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 15, 2024 Category: Rheumatology Authors: Gerd R Burmester Filip Van den Bosch John Tesser Anna Shmagel Yanxi Liu Nasser Khan Heidi S Camp Alan Kivitz Source Type: research
Myocardial metastasis from ZEB1- and TWIST-positive spindle cell carcinoma of the esophagus: A case report
CONCLUSION: To the best of our knowledge, there have been no prior reports of cardiac metastasis of esophageal SCC. This case highlights our experience with a patient with esophageal SCC who progressed rapidly and died from the disease, with the autopsy examination showing cardiac metastasis.PMID:38617457 | PMC:PMC11008411 | DOI:10.3748/wjg.v30.i11.1636 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - April 15, 2024 Category: Gastroenterology Authors: Yoshihiro Shibata Hirofumi Ohmura Kazuki Komatsu Kosuke Sagara Atsuji Matsuyama Ryuji Nakano Eishi Baba Source Type: research
Upadacitinib in Rheumatoid Arthritis and Inadequate Response to Conventional Synthetic Disease-Modifying Antirheumatic Drugs: Efficacy and Safety Through 5 Years (SELECT-NEXT)
CONCLUSION: The 5-year benefit-risk profile for upadacitinib in RA remains favorable.PMID:38621793 | DOI:10.3899/jrheum.2023-1062 (Source: J Rheumatol)
Source: J Rheumatol - April 15, 2024 Category: Rheumatology Authors: Gerd R Burmester Filip Van den Bosch John Tesser Anna Shmagel Yanxi Liu Nasser Khan Heidi S Camp Alan Kivitz Source Type: research
Myocardial metastasis from ZEB1- and TWIST-positive spindle cell carcinoma of the esophagus: A case report
CONCLUSION: To the best of our knowledge, there have been no prior reports of cardiac metastasis of esophageal SCC. This case highlights our experience with a patient with esophageal SCC who progressed rapidly and died from the disease, with the autopsy examination showing cardiac metastasis.PMID:38617457 | PMC:PMC11008411 | DOI:10.3748/wjg.v30.i11.1636 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 15, 2024 Category: Gastroenterology Authors: Yoshihiro Shibata Hirofumi Ohmura Kazuki Komatsu Kosuke Sagara Atsuji Matsuyama Ryuji Nakano Eishi Baba Source Type: research
Upadacitinib in Rheumatoid Arthritis and Inadequate Response to Conventional Synthetic Disease-Modifying Antirheumatic Drugs: Efficacy and Safety Through 5 Years (SELECT-NEXT)
CONCLUSION: The 5-year benefit-risk profile for upadacitinib in RA remains favorable.PMID:38621793 | DOI:10.3899/jrheum.2023-1062 (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 15, 2024 Category: Rheumatology Authors: Gerd R Burmester Filip Van den Bosch John Tesser Anna Shmagel Yanxi Liu Nasser Khan Heidi S Camp Alan Kivitz Source Type: research
Quantification Quality Control Emerges as A Crucial Factor to Enhance Single Cell Proteomics Data Analysis
Mol Cell Proteomics. 2024 Apr 13:100768. doi: 10.1016/j.mcpro.2024.100768. Online ahead of print.ABSTRACTMass spectrometry (MS)-based single-cell proteomics (SCP) provides us the opportunity to unbiasedly explore biological variability within cells without the limitation of antibody availability. This field is rapidly developed with the main focuses on instrument advancement, sample preparation refinement, and signal boosting methods; however, the optimal data processing and analysis are rarely investigated which holds an arduous challenge because of the high proportion of missing values and batch effect. Here, we introduc...
Source: Molecular and Cellular Proteomics : MCP - April 15, 2024 Category: Molecular Biology Authors: Sung-Huan Yu Shiau-Ching Chen Pei-Shan Wu Pei-I Kuo Ting-An Chen Hsiang-Ying Lee Miao-Hsia Lin Source Type: research
Upadacitinib in Rheumatoid Arthritis and Inadequate Response to Conventional Synthetic Disease-Modifying Antirheumatic Drugs: Efficacy and Safety Through 5 Years (SELECT-NEXT)
CONCLUSION: The 5-year benefit-risk profile for upadacitinib in RA remains favorable.PMID:38621793 | DOI:10.3899/jrheum.2023-1062 (Source: J Rheumatol)
Source: J Rheumatol - April 15, 2024 Category: Rheumatology Authors: Gerd R Burmester Filip Van den Bosch John Tesser Anna Shmagel Yanxi Liu Nasser Khan Heidi S Camp Alan Kivitz Source Type: research
Myocardial metastasis from ZEB1- and TWIST-positive spindle cell carcinoma of the esophagus: A case report
CONCLUSION: To the best of our knowledge, there have been no prior reports of cardiac metastasis of esophageal SCC. This case highlights our experience with a patient with esophageal SCC who progressed rapidly and died from the disease, with the autopsy examination showing cardiac metastasis.PMID:38617457 | PMC:PMC11008411 | DOI:10.3748/wjg.v30.i11.1636 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - April 15, 2024 Category: Gastroenterology Authors: Yoshihiro Shibata Hirofumi Ohmura Kazuki Komatsu Kosuke Sagara Atsuji Matsuyama Ryuji Nakano Eishi Baba Source Type: research
Myocardial metastasis from ZEB1- and TWIST-positive spindle cell carcinoma of the esophagus: A case report
CONCLUSION: To the best of our knowledge, there have been no prior reports of cardiac metastasis of esophageal SCC. This case highlights our experience with a patient with esophageal SCC who progressed rapidly and died from the disease, with the autopsy examination showing cardiac metastasis.PMID:38617457 | PMC:PMC11008411 | DOI:10.3748/wjg.v30.i11.1636 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 15, 2024 Category: Gastroenterology Authors: Yoshihiro Shibata Hirofumi Ohmura Kazuki Komatsu Kosuke Sagara Atsuji Matsuyama Ryuji Nakano Eishi Baba Source Type: research
Upadacitinib in Rheumatoid Arthritis and Inadequate Response to Conventional Synthetic Disease-Modifying Antirheumatic Drugs: Efficacy and Safety Through 5 Years (SELECT-NEXT)
CONCLUSION: The 5-year benefit-risk profile for upadacitinib in RA remains favorable.PMID:38621793 | DOI:10.3899/jrheum.2023-1062 (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 15, 2024 Category: Rheumatology Authors: Gerd R Burmester Filip Van den Bosch John Tesser Anna Shmagel Yanxi Liu Nasser Khan Heidi S Camp Alan Kivitz Source Type: research
Quantification Quality Control Emerges as A Crucial Factor to Enhance Single Cell Proteomics Data Analysis
Mol Cell Proteomics. 2024 Apr 13:100768. doi: 10.1016/j.mcpro.2024.100768. Online ahead of print.ABSTRACTMass spectrometry (MS)-based single-cell proteomics (SCP) provides us the opportunity to unbiasedly explore biological variability within cells without the limitation of antibody availability. This field is rapidly developed with the main focuses on instrument advancement, sample preparation refinement, and signal boosting methods; however, the optimal data processing and analysis are rarely investigated which holds an arduous challenge because of the high proportion of missing values and batch effect. Here, we introduc...
Source: Molecular and Cellular Proteomics : MCP - April 15, 2024 Category: Molecular Biology Authors: Sung-Huan Yu Shiau-Ching Chen Pei-Shan Wu Pei-I Kuo Ting-An Chen Hsiang-Ying Lee Miao-Hsia Lin Source Type: research
Upadacitinib in Rheumatoid Arthritis and Inadequate Response to Conventional Synthetic Disease-Modifying Antirheumatic Drugs: Efficacy and Safety Through 5 Years (SELECT-NEXT)
CONCLUSION: The 5-year benefit-risk profile for upadacitinib in RA remains favorable.PMID:38621793 | DOI:10.3899/jrheum.2023-1062 (Source: J Rheumatol)
Source: J Rheumatol - April 15, 2024 Category: Rheumatology Authors: Gerd R Burmester Filip Van den Bosch John Tesser Anna Shmagel Yanxi Liu Nasser Khan Heidi S Camp Alan Kivitz Source Type: research
